| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Y Ip, Y Li, G D Yancopoulos, R M Lindsa. Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 8. 1993-09-02. PMID:7688038. |
while we observed no major effect of any of the neurotrophins upon the survival of e18 hippocampal neurons, bdnf, nt-3, and nt-4, but not ngf, produced marked increases in the number of neurons expressing detectable levels of either calbindin or ache. |
1993-09-02 |
2023-08-12 |
rat |
| Z Kokaia, J Bengzon, M Metsis, M Kokaia, H Persson, O Lindval. Coexpression of neurotrophins and their receptors in neurons of the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 14. 1993-08-30. PMID:8341689. |
using double-label in situ hybridization, we demonstrate that mrnas for bdnf and its high-affinity receptor trkb are coexpressed in hippocampal and cortical neurons. |
1993-08-30 |
2023-08-12 |
Not clear |
| M Knipper, A Beck, J Rylett, H Bree. Neurotrophin induced second messenger responses in rat brain synaptosomes. Neuroreport. vol 4. issue 5. 1993-07-22. PMID:8390308. |
neurotrophins (ngf, bdnf) elicit significant elevation of camp as well as ip3-concentrations in either membrane preparations or intact isolated nerve endings from rat brain hippocampus. |
1993-07-22 |
2023-08-12 |
rat |
| C Cosi, P E Spoerri, M C Comelli, D Guidolin, S D Skape. Glucocorticoids depress activity-dependent expression of BDNF mRNA in hippocampal neurones. Neuroreport. vol 4. issue 5. 1993-07-22. PMID:8513132. |
glucocorticoids depress activity-dependent expression of bdnf mrna in hippocampal neurones. |
1993-07-22 |
2023-08-12 |
rat |
| C Cosi, P E Spoerri, M C Comelli, D Guidolin, S D Skape. Glucocorticoids depress activity-dependent expression of BDNF mRNA in hippocampal neurones. Neuroreport. vol 4. issue 5. 1993-07-22. PMID:8513132. |
here we show that dexamethasone, a synthetic glucocorticoid, prevents activity-dependent increases of brain-derived neurotrophic factor (bdnf) mrna in cultures of rat hippocampal neurones. |
1993-07-22 |
2023-08-12 |
rat |
| J B Pan, L M Monteggia, T Giordan. Altered levels and splicing of the amyloid precursor protein in the adult rat hippocampus after treatment with DMSO or retinoic acid. Brain research. Molecular brain research. vol 18. issue 3. 1993-06-24. PMID:7684485. |
on the abundance of app, the ratio of the three major isoforms, and the relative abundance of nerve growth factor (ngf), brain derived neurotrophic factor (bdnf), and neurotrophin-3 (nt-3) were determined by rtpcr in the hippocampus of aged rats. |
1993-06-24 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, K D Beck, C E Finch, S A Johnson, F Heft. BDNF and trkB mRNA expression in the hippocampal formation of aging rats. Neurobiology of aging. vol 14. issue 2. 1993-06-10. PMID:8487914. |
northern blot analysis of hippocampal rna from male fischer 344 confirmed that neither bdnf mrna nor trkb mrna levels changed with age. |
1993-06-10 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, K D Beck, C E Finch, S A Johnson, F Heft. BDNF and trkB mRNA expression in the hippocampal formation of aging rats. Neurobiology of aging. vol 14. issue 2. 1993-06-10. PMID:8487914. |
these findings suggest that age-related neurodegenerative changes, including the atrophy of the cholinergic septo-hippocampal pathway, are not the result of changes in hippocampal bdnf or trkb mrna expression. |
1993-06-10 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, K D Beck, C E Finch, S A Johnson, F Heft. BDNF and trkB mRNA expression in the hippocampal formation of aging rats. Neurobiology of aging. vol 14. issue 2. 1993-06-10. PMID:8487914. |
these findings indicate that altered hippocampal synaptic plasticity which occurs in the aged rat brain is not a reflection of changes in the expression of bdnf or trkb receptor mrna. |
1993-06-10 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, F Heft. BDNF and trkB mRNA expression in the rat hippocampus following entorhinal cortex lesions. Neuroreport. vol 4. issue 2. 1993-04-22. PMID:8453058. |
bdnf and trkb mrna expression in the rat hippocampus following entorhinal cortex lesions. |
1993-04-22 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, F Heft. BDNF and trkB mRNA expression in the rat hippocampus following entorhinal cortex lesions. Neuroreport. vol 4. issue 2. 1993-04-22. PMID:8453058. |
our findings indicate that hippocampal neuron sprouting which occurs in response to ecls is not the result of changes in the expression of the bdnf or trkb mrna. |
1993-04-22 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, F Heft. Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: evidence from lesion and chronic cholinergic drug treatment studies. Neuroscience. vol 52. issue 3. 1993-04-15. PMID:8450959. |
quantitative northern blot analysis indicated that hippocampal bdnf mrna was decreased by 29 and 68%, three weeks after partial or full unilateral fimbrial transections, respectively. |
1993-04-15 |
2023-08-12 |
rat |
| T Giordano, J B Pan, D Casuto, S Watanabe, S P Arneri. Thyroid hormone regulation of NGF, NT-3 and BDNF RNA in the adult rat brain. Brain research. Molecular brain research. vol 16. issue 3-4. 1993-04-01. PMID:1337933. |
on the relative abundances of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), and neurotrophin-3 (nt-3) rna were determined by rtpcr in the cortex and hippocampus of young adult rats. |
1993-04-01 |
2023-08-11 |
rat |
| T Giordano, J B Pan, D Casuto, S Watanabe, S P Arneri. Thyroid hormone regulation of NGF, NT-3 and BDNF RNA in the adult rat brain. Brain research. Molecular brain research. vol 16. issue 3-4. 1993-04-01. PMID:1337933. |
despite enhanced abundance of ngf in the hippocampus, chat activity was unchanged, whereas chat activity was modestly increased by 28% in the cortex without corresponding changes in ngf, nt-3 or bdnf. |
1993-04-01 |
2023-08-11 |
rat |
| J P Merlio, P Ernfors, Z Kokaia, D S Middlemas, J Bengzon, M Kokaia, M L Smith, B K Siesjö, T Hunter, O Lindval. Increased production of the TrkB protein tyrosine kinase receptor after brain insults. Neuron. vol 10. issue 2. 1993-03-26. PMID:8439408. |
these data suggest that bdnf and its receptor may play a local role within the hippocampus in kindling-associated neural plasticity and in neuronal protection following epileptic, ischemic, and hypoglycemic insults. |
1993-03-26 |
2023-08-12 |
Not clear |
| C A Altar, M R Criden, R M Lindsay, P S DiStefan. Characterization and topography of high-affinity 125I-neurotrophin-3 binding to mammalian brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 2. 1993-03-04. PMID:8426234. |
microdensitometry confirmed graphically and by hill analysis the monophasic displacement of 125i-nt-3 and the biphasic displacement of 125i-nt-3 binding by bdnf in hippocampus, caudate-putamen, neocortex, and olfactory tubercle. |
1993-03-04 |
2023-08-12 |
human |
| S R D'Mello, C Jiang, C Lamberti, S C Martin, G Heinric. Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts. Journal of neuroscience research. vol 33. issue 4. 1993-02-12. PMID:1336558. |
northern blot hybridization analysis revealed 4 discrete bdnf mrna species in l929 cells and rat hippocampus after induction of seizures with kainic acid. |
1993-02-12 |
2023-08-11 |
mouse |
| J D Roback, S J Diede, M Downen, H J Lee, J Kwon, T H Large, U Otten, B H Waine. Expression of neurotrophins and the low-affinity NGF receptor in septal and hippocampal reaggregate cultures: local physiologic effects of NGF synthesized in the septal region. Brain research. Developmental brain research. vol 70. issue 1. 1993-02-03. PMID:1473271. |
ngf, bdnf, nt-3 and lngfr were each expressed in septal and hippocampal reaggregates as well as the native septum and hippocampus. |
1993-02-03 |
2023-08-11 |
mouse |
| S L Patterson, L M Grover, P A Schwartzkroin, M Bothwel. Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron. vol 9. issue 6. 1993-01-21. PMID:1463608. |
neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing ltp in ca1 evokes increases in bdnf and nt-3 mrnas. |
1993-01-21 |
2023-08-11 |
rat |
| F Zafra, D Lindholm, E Castrén, J Hartikka, H Thoene. Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 12. 1993-01-15. PMID:1281495. |
brain-derived neurotrophic factor (bdnf) and ngf are both expressed by neurons in the hippocampus. |
1993-01-15 |
2023-08-11 |
rat |