| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Lindholm, M da Penha Berzaghi, J Cooper, H Thoenen, E Castré. Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 8. 1995-06-14. PMID:7747601. |
here we show that bdnf and neutrotrophin-4 (nt-4), but not nt-3 itself, up-regulate nt-3 mrna in cultured hippocampal neurons. |
1995-06-14 |
2023-08-12 |
rat |
| D Lindholm, M da Penha Berzaghi, J Cooper, H Thoenen, E Castré. Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 8. 1995-06-14. PMID:7747601. |
in the rat hippocampus, the muscarinic receptor agonist, pilocarpine increased bdnf mrna levels rapidly and those of nt-3 with a delay of several hours. |
1995-06-14 |
2023-08-12 |
rat |
| D Lindholm, M da Penha Berzaghi, J Cooper, H Thoenen, E Castré. Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 8. 1995-06-14. PMID:7747601. |
injection of bdnf into neonatal rats elevated nt-3 mrna in the hippocampus which demonstrates that bdnf is able to enhance nt-3 expression in vivo. |
1995-06-14 |
2023-08-12 |
rat |
| M Singh, E M Meyer, J W Simpkin. The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats. Endocrinology. vol 136. issue 5. 1995-05-23. PMID:7720680. |
twenty-eight weeks after ovx, there were also reductions in bdnf mrna in all subregions of the hippocampus except ca1 (ca2 by 38%, ca3 by 44%, ca4 by 39%, and dentate gyrus by 37%), whereas e2 replacement was effective in elevating bdnf mrna levels in the ca3, ca4, and dentate gyrus subregions. |
1995-05-23 |
2023-08-12 |
rat |
| M Singh, E M Meyer, J W Simpkin. The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats. Endocrinology. vol 136. issue 5. 1995-05-23. PMID:7720680. |
further, at the time point studied, e2 replacement is more effective in maintaining bdnf mrna in the hippocampus than in the cortex, suggesting a regional difference in the ovarian steroid requirement for expression of bdnf. |
1995-05-23 |
2023-08-12 |
rat |
| V Lessmann, K Gottmann, R Heuman. BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones. Neuroreport. vol 6. issue 1. 1995-05-09. PMID:7703418. |
bdnf and nt-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones. |
1995-05-09 |
2023-08-12 |
rat |
| V Lessmann, K Gottmann, R Heuman. BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones. Neuroreport. vol 6. issue 1. 1995-05-09. PMID:7703418. |
the effects of bdnf and nt-4/5 on ampa receptor-mediated synaptic transmission were investigated with the patch clamp technique applied to embryonic and post-natal rat hippocampal neurones, cultured in serum-free medium. |
1995-05-09 |
2023-08-12 |
rat |
| M A Smith, S Makino, R Kvetnansky, R M Pos. Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 3 Pt 1. 1995-04-20. PMID:7891134. |
we found that single or repeated immobilization markedly reduced brain-derived neurotrophic factor (bdnf) mrna levels in the dentate gyrus and hippocampus. |
1995-04-20 |
2023-08-12 |
rat |
| M A Smith, S Makino, R Kvetnansky, R M Pos. Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 3 Pt 1. 1995-04-20. PMID:7891134. |
these findings demonstrate that bdnf and nt-3 are stress-responsive genes and raise the possibility that alterations in the expression of these or other growth factors might be important in producing some of the physiological and pathophysiological effects of stress in the hippocampus. |
1995-04-20 |
2023-08-12 |
rat |
| H Kang, E M Schuma. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science (New York, N.Y.). vol 267. issue 5204. 1995-04-12. PMID:7886457. |
to test whether the neurotrophins also function in the mature nervous system, the effects of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), and neurotrophic factor 3 (nt-3) on the strength of synaptic transmission in hippocampal slices were determined. |
1995-04-12 |
2023-08-12 |
Not clear |
| M A Burke, W C Mobley, J Cho, S J Wiegand, R M Lindsay, E J Mufson, J H Kordowe. Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins. Experimental neurology. vol 130. issue 2. 1995-03-27. PMID:7867749. |
in the present study, we examined whether infusions of nerve growth factor (ngf) or brain-derived neurotrophic factor (bdnf) could prevent the loss of cholinergic septal/diagonal band neurons following excitotoxic lesions of their target neurons within the hippocampus. |
1995-03-27 |
2023-08-12 |
rat |
| M A Burke, W C Mobley, J Cho, S J Wiegand, R M Lindsay, E J Mufson, J H Kordowe. Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins. Experimental neurology. vol 130. issue 2. 1995-03-27. PMID:7867749. |
in addition, both ngf and bdnf induced a sprouting of cholinergic processes within the residual hippocampal remnant ipsilateral to the infusions. |
1995-03-27 |
2023-08-12 |
rat |
| J F Bishop, G P Mueller, M M Mouradia. Alternate 5' exons in the rat brain-derived neurotrophic factor gene: differential patterns of expression across brain regions. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854051. |
to investigate bdnf 5' exons expressed in the adult rat brain, we subjected rna from cerebellum to 5'-race analysis and compared the resulting clones to previously reported 5' exon sequences from rat brain and hippocampus. |
1995-03-16 |
2023-08-12 |
rat |
| J F Bishop, G P Mueller, M M Mouradia. Alternate 5' exons in the rat brain-derived neurotrophic factor gene: differential patterns of expression across brain regions. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854051. |
quantitative pcr analysis of bdnf mrnas containing each of the five upstream exons indicated that each of the alternate transcripts is most abundant in the hippocampus, intermediate in the substantia nigra and cerebellum and least abundant in the striatum. |
1995-03-16 |
2023-08-12 |
rat |
| H M Chao, B S McEwe. Glucocorticoids and the expression of mRNAs for neurotrophins, their receptors and GAP-43 in the rat hippocampus. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854057. |
the genes encoding brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), and basic fibroblast growth factor (bfgf) are all expressed in the adult rat hippocampus. |
1995-03-16 |
2023-08-12 |
rat |
| R C Elliott, C E Inturrisi, I B Black, C F Dreyfu. An improved method detects differential NGF and BDNF gene expression in response to depolarization in cultured hippocampal neurons. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854070. |
an improved method detects differential ngf and bdnf gene expression in response to depolarization in cultured hippocampal neurons. |
1995-03-16 |
2023-08-12 |
rat |
| R C Elliott, C E Inturrisi, I B Black, C F Dreyfu. An improved method detects differential NGF and BDNF gene expression in response to depolarization in cultured hippocampal neurons. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854070. |
to define the temporal profiles of trophin gene expression we examined nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) mrnas in dissociated cell cultures of rat hippocampus using an improved solution hybridization technique. |
1995-03-16 |
2023-08-12 |
rat |
| N Rocamora, L Massieu, H W Boddeke, J M Palacios, G Mengo. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNAs in adult rat brain after intrahippocampal injection of quinolinic acid. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854071. |
as in other excitatory paradigms, nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) mrna levels increased dramatically and transiently in dentate gyrus after the administration of 120 nmol of quin to the left hippocampus. |
1995-03-16 |
2023-08-12 |
rat |
| N Rocamora, L Massieu, H W Boddeke, J M Palacios, G Mengo. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNAs in adult rat brain after intrahippocampal injection of quinolinic acid. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854071. |
pretreatment with the non-competitive nmda antagonist mk-801 (2 mg/kg, 30 min before the insult), partially blocked the increase in both bdnf and ngf mrnas, as well as the decrease in nt3, in the contralateral hippocampus. |
1995-03-16 |
2023-08-12 |
rat |
| N Rocamora, L Massieu, H W Boddeke, J M Palacios, G Mengo. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNAs in adult rat brain after intrahippocampal injection of quinolinic acid. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854071. |
treatment with the ampa/kainate antagonist nbqx (30 mg/kg, 15 and 5 min before, and 10 min after the insult) did not influence the effect of quin upon ngf or bdnf mrna levels, although it partially prevented the hippocampal contralateral decrease in nt3 mrna. |
1995-03-16 |
2023-08-12 |
rat |