Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Draguno. A role for immediate-early transcription factors in learning and memory. Behavior genetics. vol 26. issue 3. 1996-09-18. PMID:8754252. |
the ltp studies suggest that synaptic modifications occurring during nmda-receptor-mediated hippocampal ltp and ltd are stabilized by the protein products of the krox family of iegs (as well as by brain-derived neurotrophic factor, bdnf). |
1996-09-18 |
2023-08-12 |
Not clear |
N Rocamora, E Welker, M Pascual, E Sorian. Upregulation of BDNF mRNA expression in the barrel cortex of adult mice after sensory stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 14. 1996-08-30. PMID:8699252. |
upregulation of brain-derived neurotrophic factor (bdnf) mrna expression by neuronal activity has been reported in cultured hippocampal cells and in different in vivo excitotoxic paradigms. |
1996-08-30 |
2023-08-12 |
mouse |
S L Patterson, T Abel, T A Deuel, K C Martin, J C Rose, E R Kande. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. vol 16. issue 6. 1996-08-02. PMID:8663990. |
recombinant bdnf rescues deficits in basal synaptic transmission and hippocampal ltp in bdnf knockout mice. |
1996-08-02 |
2023-08-12 |
mouse |
S L Patterson, T Abel, T A Deuel, K C Martin, J C Rose, E R Kande. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. vol 16. issue 6. 1996-08-02. PMID:8663990. |
brain-derived neurotrophic factor (bdnf) is expressed at high levels in hippocampal neurons, and its expression is modulated by neural activity. |
1996-08-02 |
2023-08-12 |
mouse |
S L Patterson, T Abel, T A Deuel, K C Martin, J C Rose, E R Kande. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. vol 16. issue 6. 1996-08-02. PMID:8663990. |
we here demonstrate that treatment of hippocampal slices from bdnf knockout mice with recombinant bdnf completely reverses deficits in long-term potentiation and significantly improves deficits in basal synaptic transmission at the schaffer collateral-ca1 synapse. |
1996-08-02 |
2023-08-12 |
mouse |
S L Patterson, T Abel, T A Deuel, K C Martin, J C Rose, E R Kande. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. vol 16. issue 6. 1996-08-02. PMID:8663990. |
thus, bdnf has an acute role in hippocampal synaptic function. |
1996-08-02 |
2023-08-12 |
mouse |
N Rocamora, M Pascual, L Acsàdy, L de Lecea, T F Freund, E Sorian. Expression of NGF and NT3 mRNAs in hippocampal interneurons innervated by the GABAergic septohippocampal pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 12. 1996-07-30. PMID:8656293. |
we used in situ hybridization for the detection of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), and neurotrophin 3 (nt3) mrnas combined with immunocytochemistry against the calcium-binding proteins parvalbumin (parv), calbindin 28k (calb), and calretinin (calr) to determine the expression of neurotrophins in functionally distinct subsets of hippocampal interneurons. |
1996-07-30 |
2023-08-12 |
Not clear |
N Rocamora, M Pascual, L Acsàdy, L de Lecea, T F Freund, E Sorian. Expression of NGF and NT3 mRNAs in hippocampal interneurons innervated by the GABAergic septohippocampal pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 12. 1996-07-30. PMID:8656293. |
small subsets of parv- and calr-positive cells expressed nt3 mrna, but we did not find hippocampal interneurons expressing bdnf mrna. |
1996-07-30 |
2023-08-12 |
Not clear |
A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
in developing hippocampus, the expression of brain derived neurotrophic factor (bdnf) and its receptor trkb increases in parallel with the ability to undergo long-term potentiation (ltp). |
1996-07-25 |
2023-08-12 |
Not clear |
A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
here we report a mechanism by which bdnf modulates hippocampal ltp. |
1996-07-25 |
2023-08-12 |
Not clear |
A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
exogenous bdnf promoted the induction of ltp by tetanic stimulation in young (postnatal day 12-13) hippocampal slices, which in the absence of bdnf show only short-term potentiation (stp). |
1996-07-25 |
2023-08-12 |
Not clear |
A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
a trkb-igg fusion protein, which scavenges endogenous bdnf, reduced the synaptic responses to tetanus as well as the magnitude of ltp in adult hippocampus. |
1996-07-25 |
2023-08-12 |
Not clear |
A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
our results suggest that bdnf may regulate ltp in developing and adult hippocampus by enhancing synaptic responses to tetanic stimulation. |
1996-07-25 |
2023-08-12 |
Not clear |
B Knusel, D R Kaplan, F Heft. Intraparenchymal NGF injections in adult and aged rats induce long-lasting Trk tyrosine phosphorylation. Experimental neurology. vol 139. issue 1. 1996-07-11. PMID:8635559. |
a similar result was obtained with 1 week of daily injections of bdnf into the hippocampus. |
1996-07-11 |
2023-08-12 |
rat |
G Mudò, X H Jiang, T Timmusk, M Bindoni, N Belluard. Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. Epilepsia. vol 37. issue 2. 1996-07-09. PMID:8635431. |
the noncompetitive n-methyl-d-aspartate (nmda) antagonist ketamine blocked ngf, bdnf, and trkb mrna increases in the hippocampus and cerebral cortex, but not in the amygdala and piriform cortex. |
1996-07-09 |
2023-08-12 |
rat |
M A Smith, S Makino, R Kvetnanský, R M Pos. Effects of stress on neurotrophic factor expression in the rat brain. Annals of the New York Academy of Sciences. vol 771. 1996-04-17. PMID:8597402. |
decreased bdnf may contribute to hippocampal damage that occurs during chronic stress or aging. |
1996-04-17 |
2023-08-12 |
rat |
Y Larmet, S Reibel, J Carnahan, H Nawa, C Marescaux, A Depauli. Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat. Neuroreport. vol 6. issue 14. 1996-02-22. PMID:8547602. |
the physiological significance of this increase was investigated by chronic intrahippocampal perfusion of bdnf in the model of dorsal hippocampal kindling in the rat. |
1996-02-22 |
2023-08-12 |
rat |
S Marty, P Carroll, A Cellerino, E Castrén, V Staiger, H Thoenen, D Lindhol. Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 2. 1996-02-22. PMID:8551351. |
the aim of this study was to investigate the effects of bdnf on the differentiation of hippocampal nonpyramidal neurons using organotypic slice cultures prepared from postnatal rats. |
1996-02-22 |
2023-08-12 |
mouse |
S Marty, P Carroll, A Cellerino, E Castrén, V Staiger, H Thoenen, D Lindhol. Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 2. 1996-02-22. PMID:8551351. |
in addition, bdnf increased calretinin immunoreactivity in cajal-retzius cells situated around the hippocampal fissure. |
1996-02-22 |
2023-08-12 |
mouse |
M M Dugich-Djordjevic, C Peterson, F Isono, F Ohsawa, H R Widmer, T L Denton, G L Bennett, F Heft. Immunohistochemical visualization of brain-derived neurotrophic factor in the rat brain. The European journal of neuroscience. vol 7. issue 9. 1996-01-31. PMID:8528456. |
bdnf was localized in all subpopulations of hippocampal neurons. |
1996-01-31 |
2023-08-12 |
rat |