| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Timmusk, H Persson, M Metsi. Analysis of transcriptional initiation and translatability of brain-derived neurotrophic factor mRNAs in the rat brain. Neuroscience letters. vol 177. issue 1-2. 1995-02-10. PMID:7824176. |
in the present study, using rnase protection analysis, we show that the same major transcription initiation sites are used for each bdnf exon mrna in different brain regions and that in addition to hippocampus and cerebral cortex, kainate differentially induces the expression of bdnf exon mrnas in thalamus, cerebellum and striatum. |
1995-02-10 |
2023-08-12 |
rat |
| S D Croll, S J Wiegand, K D Anderson, R M Lindsay, H Naw. Regulation of neuropeptides in adult rat forebrain by the neurotrophins BDNF and NGF. The European journal of neuroscience. vol 6. issue 8. 1994-12-30. PMID:7981876. |
to test this hypothesis directly, bdnf or ngf was infused into the hippocampus and cortex of adult rats. |
1994-12-30 |
2023-08-12 |
rat |
| S D Croll, S J Wiegand, K D Anderson, R M Lindsay, H Naw. Regulation of neuropeptides in adult rat forebrain by the neurotrophins BDNF and NGF. The European journal of neuroscience. vol 6. issue 8. 1994-12-30. PMID:7981876. |
bdnf produced elevations of peptide and mrna for neuropeptide y and cholecystokinin in hippocampus and cortex, and somatostatin in cortex. |
1994-12-30 |
2023-08-12 |
rat |
| S D Croll, S J Wiegand, K D Anderson, R M Lindsay, H Naw. Regulation of neuropeptides in adult rat forebrain by the neurotrophins BDNF and NGF. The European journal of neuroscience. vol 6. issue 8. 1994-12-30. PMID:7981876. |
in contrast, bdnf decreased dynorphin peptide and mrna in hippocampus. |
1994-12-30 |
2023-08-12 |
rat |
| T Timmusk, M Metsi. Regulation of BDNF promoters in the rat hippocampus. Neurochemistry international. vol 25. issue 1. 1994-12-20. PMID:7950963. |
regulation of bdnf promoters in the rat hippocampus. |
1994-12-20 |
2023-08-12 |
rat |
| T Timmusk, M Metsi. Regulation of BDNF promoters in the rat hippocampus. Neurochemistry international. vol 25. issue 1. 1994-12-20. PMID:7950963. |
we have analyzed the hippocampal expression pattern of bdnf mrna's containing different 5' exons during postnatal development. |
1994-12-20 |
2023-08-12 |
rat |
| T Timmusk, M Metsi. Regulation of BDNF promoters in the rat hippocampus. Neurochemistry international. vol 25. issue 1. 1994-12-20. PMID:7950963. |
induction of different bdnf promoters after treatment with kainic acid combined with glutamate antagonists mk801 and nbqx discloses the differential participation of different glutamate receptor subtypes in regulation of the bdnf gene in the hippocampus. |
1994-12-20 |
2023-08-12 |
rat |
| M Knipper, M da Penha Berzaghi, A Blöchl, H Breer, H Thoenen, D Lindhol. Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. The European journal of neuroscience. vol 6. issue 4. 1994-08-11. PMID:8025717. |
in the rat hippocampus, nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) are synthesized by neurons in an activity-dependent manner. |
1994-08-11 |
2023-08-12 |
rat |
| M Knipper, M da Penha Berzaghi, A Blöchl, H Breer, H Thoenen, D Lindhol. Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. The European journal of neuroscience. vol 6. issue 4. 1994-08-11. PMID:8025717. |
here we demonstrate that ngf and bdnf mrna and ngf protein are up-regulated in the rat hippocampus by the activation of muscarinic receptors. |
1994-08-11 |
2023-08-12 |
rat |
| M Knipper, M da Penha Berzaghi, A Blöchl, H Breer, H Thoenen, D Lindhol. Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. The European journal of neuroscience. vol 6. issue 4. 1994-08-11. PMID:8025717. |
conversely, ngf and bdnf enhance the release of acetylcholine (ach) from rat hippocampal synaptosomes containing the nerve endings of the septal cholinergic neurons. |
1994-08-11 |
2023-08-12 |
rat |
| M Knipper, M da Penha Berzaghi, A Blöchl, H Breer, H Thoenen, D Lindhol. Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. The European journal of neuroscience. vol 6. issue 4. 1994-08-11. PMID:8025717. |
the reciprocal regulation of ach, ngf and bdnf in the hippocampus suggests a novel molecular framework by which the neurotrophins might influence synaptic plasticity. |
1994-08-11 |
2023-08-12 |
rat |
| V E Koliatsos, D L Price, G K Gouras, M H Cayouette, L E Burton, J W Winslo. Highly selective effects of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 on intact and injured basal forebrain magnocellular neurons. The Journal of comparative neurology. vol 343. issue 2. 1994-08-10. PMID:8027442. |
ngf, bdnf, and nt-3 are enriched in hippocampus. |
1994-08-10 |
2023-08-12 |
human |
| T Beck, D Lindholm, E Castrén, A Wre. Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 14. issue 4. 1994-07-27. PMID:8014217. |
a continuous intraventricular infusion of bdnf for 7 days starting immediately before the onset of ischemia significantly increased the number of pyramidal cells in the vulnerable ca1 sector of the hippocampus. |
1994-07-27 |
2023-08-12 |
rat |
| B Cheng, M P Mattso. NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults. Brain research. vol 640. issue 1-2. 1994-07-21. PMID:7911729. |
in the present study, nt-3 and bdnf attenuated glucose deprivation-induced neuronal damage dose-dependently in rat hippocampal, septal and cortical cultures. |
1994-07-21 |
2023-08-12 |
rat |
| B Cheng, M P Mattso. NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults. Brain research. vol 640. issue 1-2. 1994-07-21. PMID:7911729. |
trkb (bdnf receptor) and trkc (nt-3 receptor) proteins were present in hippocampal, cortical and septal cultures where they were localized to neuronal cell bodies and neurites. |
1994-07-21 |
2023-08-12 |
rat |
| J L Venero, K D Beck, F Heft. 6-Hydroxydopamine lesions reduce BDNF mRNA levels in adult rat brain substantia nigra. Neuroreport. vol 5. issue 4. 1994-07-20. PMID:8003668. |
cellular levels of bdnf mrna were lower than those in bdnf expressing cortical and hippocampal neurons. |
1994-07-20 |
2023-08-12 |
rat |
| T Massamiri, M Khrestchatisky, Y Ben-Ar. Induction of c-fos mRNA expression in an in vitro hippocampal slice model of adult rats after kainate but not gamma-aminobutyric acid or bicuculline treatment. Neuroscience letters. vol 166. issue 1. 1994-06-20. PMID:8190362. |
our results also demonstrate a lack of induction of c-fos, zifl268 and bdnf after short-time treatment of either adult or newborn hippocampal slices with gaba or bicuculline. |
1994-06-20 |
2023-08-12 |
rat |
| T Tsukahara, Y Yonekawa, K Tanaka, O Ohara, S Wantanabe, T Kimura, T Nishijima, T Taniguch. The role of brain-derived neurotrophic factor in transient forebrain ischemia in the rat brain. Neurosurgery. vol 34. issue 2. 1994-06-08. PMID:8177394. |
the alterations in the bdnf messenger ribonucleic acid content in the hippocampus and the cerebral cortex were examined by northern blot analysis, using a phosphorus-32-labeled mouse bdnf complementary deoxyribonucleic acid probe. |
1994-06-08 |
2023-08-12 |
mouse |
| M Nakayama, Y Gahara, T Kitamura, O Ohar. Distinctive four promoters collectively direct expression of brain-derived neurotrophic factor gene. Brain research. Molecular brain research. vol 21. issue 3-4. 1994-06-01. PMID:8170345. |
although the analyses of the promoter usage pattern clarified many characteristic features in controlling these promoter activities, the most notable finding was that administration of kainic acid resulted in great activation of two out of the four promoters in hippocampal neurons in a regionally different manner and thus indicated the presence of two distinct signal transduction pathways for kainate-induced activation of bdnf gene expression in neurons. |
1994-06-01 |
2023-08-12 |
Not clear |
| C Wetmore, L Olson, A J Bea. Regulation of brain-derived neurotrophic factor (BDNF) expression and release from hippocampal neurons is mediated by non-NMDA type glutamate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 3 Pt 2. 1994-04-08. PMID:8126563. |
regulation of brain-derived neurotrophic factor (bdnf) expression and release from hippocampal neurons is mediated by non-nmda type glutamate receptors. |
1994-04-08 |
2023-08-12 |
Not clear |