| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
here we report a mechanism by which bdnf modulates hippocampal ltp. |
1996-07-25 |
2023-08-12 |
Not clear |
| A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
exogenous bdnf promoted the induction of ltp by tetanic stimulation in young (postnatal day 12-13) hippocampal slices, which in the absence of bdnf show only short-term potentiation (stp). |
1996-07-25 |
2023-08-12 |
Not clear |
| A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
a trkb-igg fusion protein, which scavenges endogenous bdnf, reduced the synaptic responses to tetanus as well as the magnitude of ltp in adult hippocampus. |
1996-07-25 |
2023-08-12 |
Not clear |
| A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
our results suggest that bdnf may regulate ltp in developing and adult hippocampus by enhancing synaptic responses to tetanic stimulation. |
1996-07-25 |
2023-08-12 |
Not clear |
| B Knusel, D R Kaplan, F Heft. Intraparenchymal NGF injections in adult and aged rats induce long-lasting Trk tyrosine phosphorylation. Experimental neurology. vol 139. issue 1. 1996-07-11. PMID:8635559. |
a similar result was obtained with 1 week of daily injections of bdnf into the hippocampus. |
1996-07-11 |
2023-08-12 |
rat |
| G Mudò, X H Jiang, T Timmusk, M Bindoni, N Belluard. Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. Epilepsia. vol 37. issue 2. 1996-07-09. PMID:8635431. |
the noncompetitive n-methyl-d-aspartate (nmda) antagonist ketamine blocked ngf, bdnf, and trkb mrna increases in the hippocampus and cerebral cortex, but not in the amygdala and piriform cortex. |
1996-07-09 |
2023-08-12 |
rat |
| M A Smith, S Makino, R Kvetnanský, R M Pos. Effects of stress on neurotrophic factor expression in the rat brain. Annals of the New York Academy of Sciences. vol 771. 1996-04-17. PMID:8597402. |
decreased bdnf may contribute to hippocampal damage that occurs during chronic stress or aging. |
1996-04-17 |
2023-08-12 |
rat |
| Y Larmet, S Reibel, J Carnahan, H Nawa, C Marescaux, A Depauli. Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat. Neuroreport. vol 6. issue 14. 1996-02-22. PMID:8547602. |
the physiological significance of this increase was investigated by chronic intrahippocampal perfusion of bdnf in the model of dorsal hippocampal kindling in the rat. |
1996-02-22 |
2023-08-12 |
rat |
| S Marty, P Carroll, A Cellerino, E Castrén, V Staiger, H Thoenen, D Lindhol. Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 2. 1996-02-22. PMID:8551351. |
the aim of this study was to investigate the effects of bdnf on the differentiation of hippocampal nonpyramidal neurons using organotypic slice cultures prepared from postnatal rats. |
1996-02-22 |
2023-08-12 |
mouse |
| S Marty, P Carroll, A Cellerino, E Castrén, V Staiger, H Thoenen, D Lindhol. Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 2. 1996-02-22. PMID:8551351. |
in addition, bdnf increased calretinin immunoreactivity in cajal-retzius cells situated around the hippocampal fissure. |
1996-02-22 |
2023-08-12 |
mouse |
| M M Dugich-Djordjevic, C Peterson, F Isono, F Ohsawa, H R Widmer, T L Denton, G L Bennett, F Heft. Immunohistochemical visualization of brain-derived neurotrophic factor in the rat brain. The European journal of neuroscience. vol 7. issue 9. 1996-01-31. PMID:8528456. |
bdnf was localized in all subpopulations of hippocampal neurons. |
1996-01-31 |
2023-08-12 |
rat |
| M Nibuya, S Morinobu, R S Duma. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472505. |
chronic (21 d), but not acute (1 d), administration of several different antidepressant drugs, including tranylcypromine, sertraline, desipramine, or mianserin, significantly increased bdnf mrna and all but mianserin increased trkb mrna in hippocampus. |
1995-12-26 |
2023-08-12 |
rat |
| M Nibuya, S Morinobu, R S Duma. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472505. |
furthermore, chronic administration of ecs or antidepressant drugs completely blocked the down-regulation of bdnf mrna in the hippocampus in response to restraint stress. |
1995-12-26 |
2023-08-12 |
rat |
| Z Kokaia, Q Zhao, M Kokaia, E Elmér, M Metsis, M L Smith, B K Siesjö, O Lindval. Regulation of brain-derived neurotrophic factor gene expression after transient middle cerebral artery occlusion with and without brain damage. Experimental neurology. vol 136. issue 1. 1995-12-14. PMID:7589336. |
analysis of different bdnf transcripts showed that mcao induced a marked increase of exon iii mrna but only small increases of exon i and ii mrnas in cortex and hippocampus. |
1995-12-14 |
2023-08-12 |
rat |
| J Carnahan, H Naw. Regulation of neuropeptide expression in the brain by neurotrophins. Potential role in vivo. Molecular neurobiology. vol 10. issue 2-3. 1995-11-29. PMID:7576304. |
neurotrophins administered into neonatal brain exhibited slightly different potencies for increasing these neuropeptides: the most marked increase in neuropeptide y levels was obtained in the neocortex by nt-5, whereas in the striatum and hippocampus by bdnf, although all three neurotrophins increased somatostatin similarly in all the brain regions examined. |
1995-11-29 |
2023-08-12 |
rat |
| H Nawa, J Carnahan, C Gal. BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels. The European journal of neuroscience. vol 7. issue 7. 1995-11-07. PMID:7551179. |
the highest levels of bdnf in adult rat brain were found in the hippocampus, followed by the hypothalamus, neocortex, cerebellum, thalamus and striatum. |
1995-11-07 |
2023-08-12 |
rat |
| M Korte, P Carroll, E Wolf, G Brem, H Thoenen, T Bonhoeffe. Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 19. 1995-10-23. PMID:7568031. |
these results suggest that bdnf might have a functional role in the expression of ltp in the hippocampus. |
1995-10-23 |
2023-08-12 |
mouse |
| B Berninger, S Marty, F Zafra, M da Penha Berzaghi, H Thoenen, D Lindhol. GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development (Cambridge, England). vol 121. issue 8. 1995-10-13. PMID:7671799. |
gabaergic stimulation switches from enhancing to repressing bdnf expression in rat hippocampal neurons during maturation in vitro. |
1995-10-13 |
2023-08-12 |
rat |
| B Berninger, S Marty, F Zafra, M da Penha Berzaghi, H Thoenen, D Lindhol. GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development (Cambridge, England). vol 121. issue 8. 1995-10-13. PMID:7671799. |
here we show, that gaba and the gabaa receptor agonist muscimol induce c-fos immunoreactivity and increase bdnf mrna expression in embryonic hippocampal neurons cultured for 5 days. |
1995-10-13 |
2023-08-12 |
rat |
| B Berninger, S Marty, F Zafra, M da Penha Berzaghi, H Thoenen, D Lindhol. GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development (Cambridge, England). vol 121. issue 8. 1995-10-13. PMID:7671799. |
the differential regulation of c-fos and bdnf expression by gaba and muscimol in developing and mature hippocampal neurons is due to a switch in the ability of gabaa receptors to activate voltage-gated ca2+ channels. |
1995-10-13 |
2023-08-12 |
rat |