| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W R Schäbitz, S Schwab, M Spranger, W Hack. Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 17. issue 5. 1997-07-01. PMID:9183287. |
in vivo, bdnf rescues motorneurons, hippocampal, and substantia nigral dopaminergic cells from traumatic and toxic brain injury. |
1997-07-01 |
2023-08-12 |
rat |
| K Wu, J L Xu, P C Suen, E Levine, Y Y Huang, H T Mount, S Y Lin, I B Blac. Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density. Brain research. Molecular brain research. vol 43. issue 1-2. 1997-05-29. PMID:9037544. |
recently, brain-derived neurotrophic factor (bdnf) was shown to elicit rapid increases in synaptic activity of cultured hippocampal neurons by enhancing responsiveness to excitatory input. |
1997-05-29 |
2023-08-12 |
rat |
| T Tanaka, H Saito, N Matsuk. Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 9. 1997-05-22. PMID:9096132. |
inhibition of gabaa synaptic responses by brain-derived neurotrophic factor (bdnf) in rat hippocampus. |
1997-05-22 |
2023-08-12 |
rat |
| J P Fawcett, R Aloyz, J H McLean, S Pareek, F D Miller, P S McPherson, R A Murph. Detection of brain-derived neurotrophic factor in a vesicular fraction of brain synaptosomes. The Journal of biological chemistry. vol 272. issue 14. 1997-05-08. PMID:9082996. |
the mrna encoding brain-derived neurotrophic factor (bdnf) is widely distributed in central nervous system neurons, including in hippocampus and cortex. |
1997-05-08 |
2023-08-12 |
rat |
| J P Fawcett, R Aloyz, J H McLean, S Pareek, F D Miller, P S McPherson, R A Murph. Detection of brain-derived neurotrophic factor in a vesicular fraction of brain synaptosomes. The Journal of biological chemistry. vol 272. issue 14. 1997-05-08. PMID:9082996. |
immunocytochemistry detects diffuse and punctate bdnf staining within cell bodies and processes of cortical neurons from kainic acid-treated rats, as well as in mossy fiber terminals of rat hippocampus. |
1997-05-08 |
2023-08-12 |
rat |
| G W Mathern, T L Babb, P E Micevych, C E Blanco, J K Pretoriu. Granule cell mRNA levels for BDNF, NGF, and NT-3 correlate with neuron losses or supragranular mossy fiber sprouting in the chronically damaged and epileptic human hippocampus. Molecular and chemical neuropathology. vol 30. issue 1-2. 1997-05-06. PMID:9138429. |
granule cell mrna levels for bdnf, ngf, and nt-3 correlate with neuron losses or supragranular mossy fiber sprouting in the chronically damaged and epileptic human hippocampus. |
1997-05-06 |
2023-08-12 |
human |
| M Hayashi, A Yamashita, K Shimiz. Somatostatin and brain-derived neurotrophic factor mRNA expression in the primate brain: decreased levels of mRNAs during aging. Brain research. vol 749. issue 2. 1997-05-06. PMID:9138728. |
bdnf mrna was expressed in the various cerebral subdivisions and in the hippocampus. |
1997-05-06 |
2023-08-12 |
monkey |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
administration of a hallucinogenic 5-ht2a /2c receptor agonist, but not a 5-ht1a receptor agonist, resulted in a significant but differential regulation of bdnf mrna levels in hippocampus and neocortex. |
1997-04-28 |
2023-08-12 |
Not clear |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
in the hippocampus, the 5-ht2a /2c receptor agonist significantly decreased bdnf mrna expression in the dentate gyrus granule cell layer but did not influence expression of the neurotrophin in the ca subfields. |
1997-04-28 |
2023-08-12 |
Not clear |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
the effect of the 5-ht2a /2c receptor agonist on bdnf mrna in both the hippocampus and the neocortex was blocked by pretreatment with a selective 5-ht2a, but not 5-ht2c, receptor antagonist. |
1997-04-28 |
2023-08-12 |
Not clear |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
the expression of bdnf mrna in the hippocampus is reported to be decreased by stress, raising the possibility that the 5-ht2a receptor mediates this effect. |
1997-04-28 |
2023-08-12 |
Not clear |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
pretreatment with ketanserin, a 5-ht2a /2c receptor antagonist, significantly blocked the stress-induced downregulation of bdnf mrna in hippocampus, in support of this hypothesis. |
1997-04-28 |
2023-08-12 |
Not clear |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
the results of this study raise the possibility that regulation of bdnf expression by hallucinogenic 5-ht2a receptor agonists leads to adaptations of synaptic strength in the hippocampus and the neocortex that may mediate some of the acute and long-term behavioral effects of these agents. |
1997-04-28 |
2023-08-12 |
Not clear |
| M Korte, V Staiger, O Griesbeck, H Thoenen, T Bonhoeffe. The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments. Journal of physiology, Paris. vol 90. issue 3-4. 1997-04-24. PMID:9116659. |
these results suggest that bdnf has an important functional role in the expression of ltp in the hippocampus. |
1997-04-24 |
2023-08-12 |
mouse |
| A Androutsellis-Theotokis, W J McCormack, H F Bradford, G M Stern, F B Pliego-River. The depolarisation-induced release of [125I]BDNF from brain tissue. Brain research. vol 743. issue 1-2. 1997-04-17. PMID:9017228. |
rat brain slices from cerebral cortex and synaptosomes from cerebral cortex and hippocampus were preloaded with [125i]bdnf. |
1997-04-17 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
synthesis of the neurotrophic factor brain-derived neurotrophic factor (bdnf) and its receptor trkb in the hippocampus have been proposed to be influenced by endogenous glutamate. |
1997-04-16 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
to test this hypothesis we have investigated if increases in bdnf and trkb mrnas are associated with changes in the synaptic release of glutamate in the dorsal hippocampus in the conscious rat by combining the technique of in vivo microdialysis with in situ hybridization histochemistry. |
1997-04-16 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
levels of bdnf and trkb mrnas were increased in the hippocampus in a dose-dependent fashion following the stimulations. |
1997-04-16 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
the extracellular levels of glutamate in individual animals correlated to the levels of bdnf and trkb mrnas in the dorsal ca1 region of the hippocampus. |
1997-04-16 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
this study provides for the first time evidence of an entorhinal cortex influenced concentration-dependent relationship between the release of endogenous glutamate in vivo and neuronal expression of mrnas for bdnf and its receptor trkb in the hippocampus. |
1997-04-16 |
2023-08-12 |
rat |