| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Cellerino, P Carroll, H Thoenen, Y A Bard. Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor. Molecular and cellular neurosciences. vol 9. issue 5-6. 1998-01-08. PMID:9361277. |
intraventricular injections of bdnf into the ventricles of wild-type mice at p10 and p12 up-regulated expression of plp in the hippocampus at p14. |
1998-01-08 |
2023-08-12 |
mouse |
| E Tongiorgi, M Righi, A Cattane. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 24. 1998-01-07. PMID:9391005. |
activity-dependent dendritic targeting of bdnf and trkb mrnas in hippocampal neurons. |
1998-01-07 |
2023-08-12 |
Not clear |
| E Tongiorgi, M Righi, A Cattane. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 24. 1998-01-07. PMID:9391005. |
we show that in cultured hippocampal neurons, the mrnas for bdnf and trkb have a somatodendritic localization, and we quantify the extent of their dendritic mrna localization. |
1998-01-07 |
2023-08-12 |
Not clear |
| E Tongiorgi, M Righi, A Cattane. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 24. 1998-01-07. PMID:9391005. |
at the protein level, a brief stimulation of hippocampal neurons with 10 mm kcl leads to a marked increase of bdnf and trkb immunofluorescence density in the distal portion of dendrites, which also occurs, even if at lower levels, when transport is inhibited by nocodazole. |
1998-01-07 |
2023-08-12 |
Not clear |
| S Finkbeiner, S F Tavazoie, A Maloratsky, K M Jacobs, K M Harris, M E Greenber. CREB: a major mediator of neuronal neurotrophin responses. Neuron. vol 19. issue 5. 1997-12-29. PMID:9390517. |
to understand how neurotrophins elicit such diverse responses, we elucidated signaling pathways by which brain-derived neurotrophic factor (bdnf) activates gene expression in cultured neurons and hippocampal slices. |
1997-12-29 |
2023-08-12 |
Not clear |
| C R Jarvis, Z G Xiong, J R Plant, D Churchill, W Y Lu, B A MacVicar, J F MacDonal. Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons. Journal of neurophysiology. vol 78. issue 5. 1997-12-22. PMID:9356388. |
patch-clamp and calcium imaging techniques were used to assess the acute effects of the neurotrophins, brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), and nerve growth factor (ngf), on the responses of cultured and acutely isolated hippocampal and cultured striatal neurons to the glutamate receptor agonist n-methyl--aspartic acid (nmda). |
1997-12-22 |
2023-08-12 |
rat |
| C R Jarvis, Z G Xiong, J R Plant, D Churchill, W Y Lu, B A MacVicar, J F MacDonal. Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons. Journal of neurophysiology. vol 78. issue 5. 1997-12-22. PMID:9356388. |
bdnf also reversibly increased the probability of opening of nmda channels recorded from outside-out patches taken from cultured hippocampal neurons. |
1997-12-22 |
2023-08-12 |
rat |
| M A Smith, G Cizz. Stress-induced changes in brain-derived neurotrophic factor expression are attenuated in aged Fischer 344/N rats. Neurobiology of aging. vol 17. issue 6. 1997-12-04. PMID:9363796. |
the ability of acute immobilization stress (2 h) to modulate bdnf mrna levels in old rats was significantly reduced both in the hippocampus (a smaller decrease in bdnf) and the pvn (a smaller increase in bdnf) compared to young rats. |
1997-12-04 |
2023-08-12 |
rat |
| H Andersson, E Lindqvist, L Olso. Downregulation of brain-derived neurotrophic factor mRNA in adult rat brain after acute administration of methylmercury. Molecular and chemical neuropathology. vol 31. issue 3. 1997-11-26. PMID:9336765. |
decreases in brain-derived neurotrophic (bdnf) mrna labeling intensities were seen in the dentate gyrus (dg; 44% of controls), and in the ca1 (72% of controls) and ca3c (70% of controls) cell layers of hippocampus after 8 mg mehg/kg (ip) at 4 h, and at 1 h only in the dg. |
1997-11-26 |
2023-08-12 |
rat |
| H Andersson, E Lindqvist, L Olso. Downregulation of brain-derived neurotrophic factor mRNA in adult rat brain after acute administration of methylmercury. Molecular and chemical neuropathology. vol 31. issue 3. 1997-11-26. PMID:9336765. |
no significant changes could be detected in mrna levels of the bdnf high-affinity receptor trkb or neurotrophin-3 mrna at either 1 h, 4 h, or 3 d. cresyl violet staining and gfap immunohistochemistry did not reveal any major neuropathology in hippocampus at 2 wk. |
1997-11-26 |
2023-08-12 |
rat |
| P R Blanquet, Y Lamou. Brain-derived neurotrophic factor increases Ca2+/calmodulin-dependent protein kinase 2 activity in hippocampus. The Journal of biological chemistry. vol 272. issue 39. 1997-10-23. PMID:9305859. |
here we show that brain-derived neurotrophic factor (bdnf) stimulates both the phosphorylation of the ca2+/calmodulin-dependent protein kinase 2 (camk2) and its kinase activity in rat hippocampal slices. |
1997-10-23 |
2023-08-12 |
rat |
| H E Scharfma. Hyperexcitability in combined entorhinal/hippocampal slices of adult rat after exposure to brain-derived neurotrophic factor. Journal of neurophysiology. vol 78. issue 2. 1997-10-23. PMID:9307136. |
effects of brain-derived neurotrophic factor (bdnf) in area ca3, the dentate gyrus, and medial entorhinal cortex were examined electrophysiologically by bath application of bdnf in slices containing the hippocampus and entorhinal cortex. |
1997-10-23 |
2023-08-12 |
rat |
| Y K Kwo. Expression of brain-derived neurotrophic factor mRNA stimulated by basic fibroblast growth factor and platelet-derived growth factor in rat hippocampal cell line. Molecules and cells. vol 7. issue 3. 1997-10-06. PMID:9264017. |
bdnf mrna is expressed at high levels in hippocampus and bdnf serves as a trophic factor in primary cultures of rat hippocampus. |
1997-10-06 |
2023-08-12 |
rat |
| Y K Kwo. Expression of brain-derived neurotrophic factor mRNA stimulated by basic fibroblast growth factor and platelet-derived growth factor in rat hippocampal cell line. Molecules and cells. vol 7. issue 3. 1997-10-06. PMID:9264017. |
this report demonstrates that hib5 cells express a functionally active pdgf beta receptor and that pdgf and bfgf stimulate the expression of bdnf within 2 h. these results propose that bdnf is a candidate mediator of trophic effects of pdgf and bfgf in the hippocampal stem cell line hib5. |
1997-10-06 |
2023-08-12 |
rat |
| C A Willson, I Hani. Brain-derived neurotrophic factor induced stimulation of septal choline acetyltransferase activity in ethylcholine mustard aziridinium treated rats. Neuroscience letters. vol 229. issue 3. 1997-09-24. PMID:9237480. |
bdnf infusion (at a dose range of 0.1-171 microg) into either the lateral ventricle or hippocampus of af64a-treated rats for 14 days increased septal chat activity (26% and 41%, respectively). |
1997-09-24 |
2023-08-12 |
rat |
| C A Willson, I Hani. Brain-derived neurotrophic factor induced stimulation of septal choline acetyltransferase activity in ethylcholine mustard aziridinium treated rats. Neuroscience letters. vol 229. issue 3. 1997-09-24. PMID:9237480. |
bdnf did not reverse the decrease in hippocampal chat activity (20-60%) produced by af64a. |
1997-09-24 |
2023-08-12 |
rat |
| S Lee, J Williamson, E W Lothman, F G Szele, M F Chesselet, S Von Hagen, R M Sapolsky, M P Mattson, S Christako. Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment. Brain research. Molecular brain research. vol 47. issue 1-2. 1997-09-17. PMID:9221916. |
early induction of mrna for calbindin-d28k and bdnf but not nt-3 in rat hippocampus after kainic acid treatment. |
1997-09-17 |
2023-08-12 |
rat |
| S Lee, J Williamson, E W Lothman, F G Szele, M F Chesselet, S Von Hagen, R M Sapolsky, M P Mattson, S Christako. Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment. Brain research. Molecular brain research. vol 47. issue 1-2. 1997-09-17. PMID:9221916. |
the influence of kainic acid (ka), which induces acute seizures, on expression of mrna for the calcium-binding protein, calbindin-d28k, brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3) and early-response genes [c-fos, zif268 (ngfi-a), nur77 (ngfi-b)] was examined in rat hippocampus by northern blot analysis. |
1997-09-17 |
2023-08-12 |
rat |
| H Andersson, C Wetmore, E Lindqvist, J Luthman, L Olso. Trimethyltin exposure in the rat induces delayed changes in brain-derived neurotrophic factor, fos and heat shock protein 70. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9215997. |
no significant alterations in the bdnf mrna were detected in hippocampus and cerebral cortex 1 and 4 h after 8 mg tmt/kg. |
1997-09-09 |
2023-08-12 |
rat |
| H Andersson, C Wetmore, E Lindqvist, J Luthman, L Olso. Trimethyltin exposure in the rat induces delayed changes in brain-derived neurotrophic factor, fos and heat shock protein 70. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9215997. |
no significant change in bdnf immunoreactivity was seen in hippocampus or cerebral cortex 3 days after tmt. |
1997-09-09 |
2023-08-12 |
rat |