| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R B Gibb. Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement. Brain research. vol 787. issue 2. 1998-07-10. PMID:9518642. |
in the present study, quantitative in situ hybridization techniques were used to determine whether the levels of trka mrna in the basal forebrain, and nerve growth factor (ngf) mrna and brain-derived neurotrophic factor (bdnf) mrna in the hippocampus, are significantly affected by physiological changes in circulating gonadal steroids. |
1998-07-10 |
2023-08-12 |
Not clear |
| R B Gibb. Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement. Brain research. vol 787. issue 2. 1998-07-10. PMID:9518642. |
in gonadally intact animals, significant fluctuations in the levels of trka mrna in the medial septum (ms), and bdnf mrna in regions ca1 and ca3/4 of the hippocampus, were detected across the estrous cycle. |
1998-07-10 |
2023-08-12 |
Not clear |
| R B Gibb. Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement. Brain research. vol 787. issue 2. 1998-07-10. PMID:9518642. |
these data demonstrate that levels of trka mrna in the ms, and bdnf mrna in the hippocampus, are affected by physiological changes in the levels of circulating gonadal steroids and are elevated in response to acute hormone replacement. |
1998-07-10 |
2023-08-12 |
Not clear |
| J L Venero, F Heft. Regionally specific induction of BDNF and truncated trkB.T1 receptors in the hippocampal formation after intraseptal injection of kainic acid. Brain research. vol 790. issue 1-2. 1998-07-07. PMID:9593933. |
the septo-hippocampal cholinergic and gabaergic systems were lesioned with single unilateral injections of kainic acid (ka) into the septum to further characterize the role of these afferents in the regulation of hippocampal brain-derived neurotrophic factor (bdnf) expression. |
1998-07-07 |
2023-08-12 |
Not clear |
| J L Venero, F Heft. Regionally specific induction of BDNF and truncated trkB.T1 receptors in the hippocampal formation after intraseptal injection of kainic acid. Brain research. vol 790. issue 1-2. 1998-07-07. PMID:9593933. |
the lesion resulted in a complete loss of ca3 pyramidal cells, and robust increases in bdnf mrna levels in hippocampal granular dentate cells and in the amygdala. |
1998-07-07 |
2023-08-12 |
Not clear |
| J L Venero, F Heft. Regionally specific induction of BDNF and truncated trkB.T1 receptors in the hippocampal formation after intraseptal injection of kainic acid. Brain research. vol 790. issue 1-2. 1998-07-07. PMID:9593933. |
the prolonged induction of bdnf mrna levels suggests an important role of this neurotrophin, possibly mediated by truncated trkb receptors, in the regulation of hippocampal plasticity following injury. |
1998-07-07 |
2023-08-12 |
Not clear |
| H van Praag, P M Qu, R C Elliott, H Wu, C F Dreyfus, I B Blac. Unilateral hippocampal lesions in newborn and adult rats: effects on spatial memory and BDNF gene expression. Behavioural brain research. vol 92. issue 1. 1998-06-26. PMID:9588682. |
unilateral hippocampal lesions in newborn and adult rats: effects on spatial memory and bdnf gene expression. |
1998-06-26 |
2023-08-12 |
rat |
| H van Praag, P M Qu, R C Elliott, H Wu, C F Dreyfus, I B Blac. Unilateral hippocampal lesions in newborn and adult rats: effects on spatial memory and BDNF gene expression. Behavioural brain research. vol 92. issue 1. 1998-06-26. PMID:9588682. |
in addition, nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) mrna levels were assayed in the remaining (contralateral) hippocampus. |
1998-06-26 |
2023-08-12 |
rat |
| I Ferrer, J Ballabriga, E Martí, E Pérez, J Alberch, E Arena. BDNF up-regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia. Brain pathology (Zurich, Switzerland). vol 8. issue 2. 1998-06-12. PMID:9546284. |
bdnf expression, as revealed by immunohistochemistry, is found in the pre-subiculum, ca1, ca3, and dentate gyrus of the hippocampus. |
1998-06-12 |
2023-08-12 |
Not clear |
| K Morimoto, K Sato, S Sato, N Yamada, T Hayabar. Time-dependent changes in neurotrophic factor mRNA expression after kindling and long-term potentiation in rats. Brain research bulletin. vol 45. issue 6. 1998-06-08. PMID:9566504. |
these results suggest that bdnf and ngf are involved in enhancement of synaptic efficacy in the granule cells of the dentate gyrus in the hippocampus in kindling, not related to the neuronal excitability associated with seizure activity. |
1998-06-08 |
2023-08-12 |
rat |
| H G Lüesse, T Roskoden, R Linke, U Otten, K Heese, H Schwegle. Modulation of mRNA expression of the neurotrophins of the nerve growth factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. I. Expression of nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin 4 mRNA. Experimental brain research. vol 119. issue 1. 1998-05-21. PMID:9521530. |
in hippocampus of hyperthyroid rats, as compared to controls, we found higher levels of bdnf and nt-3 mrna over the total investigation period, whereas in the septum a thyroxine-dependent increase in nt-3 mrna expression was observed. |
1998-05-21 |
2023-08-12 |
rat |
| F Q Liang, R Walline, D J Earnes. Circadian rhythm of brain-derived neurotrophic factor in the rat suprachiasmatic nucleus. Neuroscience letters. vol 242. issue 2. 1998-05-14. PMID:9533401. |
in contrast, the hippocampus showed no sign of circadian rhythmicity in its expression of bdnf mrna and protein. |
1998-05-14 |
2023-08-12 |
rat |
| S Linnarsson, A Björklund, P Ernfor. Learning deficit in BDNF mutant mice. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517463. |
brain-derived neurotrophic factor (bdnf) has been implicated in the regulation of high-frequency synaptic transmission and long-term potentiation in the hippocampus, processes that are also thought to be involved in the learning of spatial tasks such as the morris water maze. |
1998-04-24 |
2023-08-12 |
mouse |
| P E Hughes, D Young, K M Preston, Q Yan, M Draguno. Differential regulation by MK801 of immediate-early genes, brain-derived neurotrophic factor and trk receptor mRNA induced by a kindling after-discharge. Brain research. Molecular brain research. vol 53. issue 1-2. 1998-04-20. PMID:9473635. |
to further examine the link between kindling, changes in gene expression and the nmda receptor, we examined the effects of mk801 on neuronal induction of immediate-early genes, brain-derived neurotrophic factor (bdnf) and trk receptor mrna expression produced by a single electrically induced hippocampal after-discharge in rats. |
1998-04-20 |
2023-08-12 |
rat |
| E Bednarski, J C Lauterborn, C M Gall, G Lync. Lysosomal dysfunction reduces brain-derived neurotrophic factor expression. Experimental neurology. vol 150. issue 1. 1998-04-14. PMID:9514826. |
brain-derived neurotrophic factor (bdnf) expression in hippocampus and cortex is considerably reduced in alzheimer's disease. |
1998-04-14 |
2023-08-12 |
Not clear |
| E Bednarski, J C Lauterborn, C M Gall, G Lync. Lysosomal dysfunction reduces brain-derived neurotrophic factor expression. Experimental neurology. vol 150. issue 1. 1998-04-14. PMID:9514826. |
cultured hippocampal slices were incubated with n- cbz-l-phenylalanyl-l-alanine-diazomethylketone (zpad), an inhibitor of cathepsins b and l, for 6 days and processed for in situ hybridization using radiolabeled crna probes against bdnf mrna. |
1998-04-14 |
2023-08-12 |
Not clear |
| J S Rudge, P E Mather, E M Pasnikowski, N Cai, T Corcoran, A Acheson, K Anderson, R M Lindsay, S J Wiegan. Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Experimental neurology. vol 149. issue 2. 1998-03-31. PMID:9500963. |
endogenous bdnf protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous bdnf is not neuroprotective. |
1998-03-31 |
2023-08-12 |
rat |
| J S Rudge, P E Mather, E M Pasnikowski, N Cai, T Corcoran, A Acheson, K Anderson, R M Lindsay, S J Wiegan. Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Experimental neurology. vol 149. issue 2. 1998-03-31. PMID:9500963. |
we show here that bdnf protein is increased after excitotoxic insult in specific areas of the hippocampus, reaching maximal levels 24 h after the insult. |
1998-03-31 |
2023-08-12 |
rat |
| J S Rudge, P E Mather, E M Pasnikowski, N Cai, T Corcoran, A Acheson, K Anderson, R M Lindsay, S J Wiegan. Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Experimental neurology. vol 149. issue 2. 1998-03-31. PMID:9500963. |
bdnf protein levels in the hippocampus increase in direct relation to the severity of seizure. |
1998-03-31 |
2023-08-12 |
rat |
| J S Rudge, P E Mather, E M Pasnikowski, N Cai, T Corcoran, A Acheson, K Anderson, R M Lindsay, S J Wiegan. Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Experimental neurology. vol 149. issue 2. 1998-03-31. PMID:9500963. |
up to 7 days after injection of kainic acid, levels of full-length trkb protein were unchanged, whereas levels of truncated trkb protein were significantly increased by 12 h. to determine whether elevations in bdnf protein levels are potentially beneficial to hippocampal neurons exposed to an excitotoxic stress, we infused exogenous bdnf prior to and during the period of neuronal death caused by kainic acid. |
1998-03-31 |
2023-08-12 |
rat |