| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Morimoto, K Sato, S Sato, N Yamada, T Hayabar. Time-dependent changes in neurotrophic factor mRNA expression after kindling and long-term potentiation in rats. Brain research bulletin. vol 45. issue 6. 1998-06-08. PMID:9566504. |
these results suggest that bdnf and ngf are involved in enhancement of synaptic efficacy in the granule cells of the dentate gyrus in the hippocampus in kindling, not related to the neuronal excitability associated with seizure activity. |
1998-06-08 |
2023-08-12 |
rat |
| H G Lüesse, T Roskoden, R Linke, U Otten, K Heese, H Schwegle. Modulation of mRNA expression of the neurotrophins of the nerve growth factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. I. Expression of nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin 4 mRNA. Experimental brain research. vol 119. issue 1. 1998-05-21. PMID:9521530. |
in hippocampus of hyperthyroid rats, as compared to controls, we found higher levels of bdnf and nt-3 mrna over the total investigation period, whereas in the septum a thyroxine-dependent increase in nt-3 mrna expression was observed. |
1998-05-21 |
2023-08-12 |
rat |
| F Q Liang, R Walline, D J Earnes. Circadian rhythm of brain-derived neurotrophic factor in the rat suprachiasmatic nucleus. Neuroscience letters. vol 242. issue 2. 1998-05-14. PMID:9533401. |
in contrast, the hippocampus showed no sign of circadian rhythmicity in its expression of bdnf mrna and protein. |
1998-05-14 |
2023-08-12 |
rat |
| S Linnarsson, A Björklund, P Ernfor. Learning deficit in BDNF mutant mice. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517463. |
brain-derived neurotrophic factor (bdnf) has been implicated in the regulation of high-frequency synaptic transmission and long-term potentiation in the hippocampus, processes that are also thought to be involved in the learning of spatial tasks such as the morris water maze. |
1998-04-24 |
2023-08-12 |
mouse |
| P E Hughes, D Young, K M Preston, Q Yan, M Draguno. Differential regulation by MK801 of immediate-early genes, brain-derived neurotrophic factor and trk receptor mRNA induced by a kindling after-discharge. Brain research. Molecular brain research. vol 53. issue 1-2. 1998-04-20. PMID:9473635. |
to further examine the link between kindling, changes in gene expression and the nmda receptor, we examined the effects of mk801 on neuronal induction of immediate-early genes, brain-derived neurotrophic factor (bdnf) and trk receptor mrna expression produced by a single electrically induced hippocampal after-discharge in rats. |
1998-04-20 |
2023-08-12 |
rat |
| E Bednarski, J C Lauterborn, C M Gall, G Lync. Lysosomal dysfunction reduces brain-derived neurotrophic factor expression. Experimental neurology. vol 150. issue 1. 1998-04-14. PMID:9514826. |
brain-derived neurotrophic factor (bdnf) expression in hippocampus and cortex is considerably reduced in alzheimer's disease. |
1998-04-14 |
2023-08-12 |
Not clear |
| E Bednarski, J C Lauterborn, C M Gall, G Lync. Lysosomal dysfunction reduces brain-derived neurotrophic factor expression. Experimental neurology. vol 150. issue 1. 1998-04-14. PMID:9514826. |
cultured hippocampal slices were incubated with n- cbz-l-phenylalanyl-l-alanine-diazomethylketone (zpad), an inhibitor of cathepsins b and l, for 6 days and processed for in situ hybridization using radiolabeled crna probes against bdnf mrna. |
1998-04-14 |
2023-08-12 |
Not clear |
| J S Rudge, P E Mather, E M Pasnikowski, N Cai, T Corcoran, A Acheson, K Anderson, R M Lindsay, S J Wiegan. Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Experimental neurology. vol 149. issue 2. 1998-03-31. PMID:9500963. |
endogenous bdnf protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous bdnf is not neuroprotective. |
1998-03-31 |
2023-08-12 |
rat |
| J S Rudge, P E Mather, E M Pasnikowski, N Cai, T Corcoran, A Acheson, K Anderson, R M Lindsay, S J Wiegan. Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Experimental neurology. vol 149. issue 2. 1998-03-31. PMID:9500963. |
we show here that bdnf protein is increased after excitotoxic insult in specific areas of the hippocampus, reaching maximal levels 24 h after the insult. |
1998-03-31 |
2023-08-12 |
rat |
| J S Rudge, P E Mather, E M Pasnikowski, N Cai, T Corcoran, A Acheson, K Anderson, R M Lindsay, S J Wiegan. Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Experimental neurology. vol 149. issue 2. 1998-03-31. PMID:9500963. |
bdnf protein levels in the hippocampus increase in direct relation to the severity of seizure. |
1998-03-31 |
2023-08-12 |
rat |
| J S Rudge, P E Mather, E M Pasnikowski, N Cai, T Corcoran, A Acheson, K Anderson, R M Lindsay, S J Wiegan. Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Experimental neurology. vol 149. issue 2. 1998-03-31. PMID:9500963. |
up to 7 days after injection of kainic acid, levels of full-length trkb protein were unchanged, whereas levels of truncated trkb protein were significantly increased by 12 h. to determine whether elevations in bdnf protein levels are potentially beneficial to hippocampal neurons exposed to an excitotoxic stress, we infused exogenous bdnf prior to and during the period of neuronal death caused by kainic acid. |
1998-03-31 |
2023-08-12 |
rat |
| Y Nakagami, H Saito, N Matsuk. Basic fibroblast growth factor and brain-derived neurotrophic factor promote survival and neuronal circuit formation in organotypic hippocampal culture. Japanese journal of pharmacology. vol 75. issue 4. 1998-03-24. PMID:9469637. |
optical recording also demonstrated that addition of 10 ng/ml bfgf or 50 ng/ml bdnf enhanced optical signals in all hippocampal areas significantly. |
1998-03-24 |
2023-08-12 |
Not clear |
| Y Nakagami, H Saito, N Matsuk. Basic fibroblast growth factor and brain-derived neurotrophic factor promote survival and neuronal circuit formation in organotypic hippocampal culture. Japanese journal of pharmacology. vol 75. issue 4. 1998-03-24. PMID:9469637. |
these data strongly suggest that bfgf and bdnf promote the formation of neuronal circuits as well as survival and that optical recording of organotypic hippocampal slices would be a useful technique that enables us to analyze neuronal circuit formation easily. |
1998-03-24 |
2023-08-12 |
Not clear |
| T F Hsieh, S Simler, M Vergnes, P Gass, C Marescaux, S J Wiegand, M Zimmermann, T Herdege. BDNF restores the expression of Jun and Fos inducible transcription factors in the rat brain following repetitive electroconvulsive seizures. Experimental neurology. vol 149. issue 1. 1998-03-06. PMID:9454625. |
in order to study the maintenance of c-fos expression during repetitive seizures, brain-derived neurotrophic factor (bdnf) was applied in parallel for 5 or 10 days via miniosmotic pumps and permanent cannula targeted at the hippocampus or the parietal cortex. |
1998-03-06 |
2023-08-12 |
rat |
| T F Hsieh, S Simler, M Vergnes, P Gass, C Marescaux, S J Wiegand, M Zimmermann, T Herdege. BDNF restores the expression of Jun and Fos inducible transcription factors in the rat brain following repetitive electroconvulsive seizures. Experimental neurology. vol 149. issue 1. 1998-03-06. PMID:9454625. |
bdnf had no effect on the expression patterns in the hippocampus. |
1998-03-06 |
2023-08-12 |
rat |
| N Sakai, M Yamada, T Numakawa, A Ogura, H Hatanak. BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons. Brain research. vol 778. issue 2. 1998-03-03. PMID:9459549. |
bdnf potentiates spontaneous ca2+ oscillations in cultured hippocampal neurons. |
1998-03-03 |
2023-08-12 |
rat |
| N Sakai, M Yamada, T Numakawa, A Ogura, H Hatanak. BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons. Brain research. vol 778. issue 2. 1998-03-03. PMID:9459549. |
we monitored changes in the intracellular calcium (ca2+) levels induced by bdnf using a fluorescence ca2+ indicator (fluo-3) by means of confocal laser microscopy in rat cultured hippocampal neurons. |
1998-03-03 |
2023-08-12 |
rat |
| N Sakai, M Yamada, T Numakawa, A Ogura, H Hatanak. BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons. Brain research. vol 778. issue 2. 1998-03-03. PMID:9459549. |
bdnf may have the potential to modulate spontaneous ca2+ oscillations to regulate neuronal plasticity in developing hippocampal neurons. |
1998-03-03 |
2023-08-12 |
rat |
| A Kadari, J M Windisch, T Ebendal, R Schneider, C Humpe. Cell death of adult pyramidal CA1 neurons after intraventricular injection of a novel peptide derived from trkA. Journal of neuroscience research. vol 50. issue 3. 1998-02-19. PMID:9364325. |
since the highest concentration of neurotrophins [ngf, brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3)] is found in the hippocampus, the peptides were injected into the 3rd ventricle of anesthetized adult rats. |
1998-02-19 |
2023-08-12 |
rat |
| R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
alterations in bdnf and nt-3 mrnas in rat hippocampus after experimental brain trauma. |
1998-02-17 |
2023-08-12 |
rat |