| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Frerking, R C Malenka, R A Nicol. Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus. Journal of neurophysiology. vol 80. issue 6. 1999-02-10. PMID:9862938. |
brain-derived neurotrophic factor (bdnf) modulates inhibitory, but not excitatory, transmission in the ca1 region of the hippocampus. |
1999-02-10 |
2023-08-12 |
Not clear |
| M Frerking, R C Malenka, R A Nicol. Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus. Journal of neurophysiology. vol 80. issue 6. 1999-02-10. PMID:9862938. |
brain-derived neurotrophic factor (bdnf) has been reported to have rapid effects on synaptic transmission in the hippocampus. |
1999-02-10 |
2023-08-12 |
Not clear |
| M Frerking, R C Malenka, R A Nicol. Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus. Journal of neurophysiology. vol 80. issue 6. 1999-02-10. PMID:9862938. |
we conclude that bdnf has a selective depressant action on inhibitory transmission in the hippocampus, due at least in part to a presynaptic mechanism. |
1999-02-10 |
2023-08-12 |
Not clear |
| R Katoh-Semba, R Semba, I K Takeuchi, K Kat. Age-related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: a comparison to those of nerve growth factor and neurotrophin-3. Neuroscience research. vol 31. issue 3. 1999-02-05. PMID:9809668. |
the concentration of bdnf increased with age in the rat hippocampus while it decreased in the rat cerebral cortex. |
1999-02-05 |
2023-08-12 |
mouse |
| R Katoh-Semba, R Semba, I K Takeuchi, K Kat. Age-related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: a comparison to those of nerve growth factor and neurotrophin-3. Neuroscience research. vol 31. issue 3. 1999-02-05. PMID:9809668. |
the level of bdnf in the hippocampus from aged rats was about 260%, of that in the same region from young adult rats. |
1999-02-05 |
2023-08-12 |
mouse |
| R Katoh-Semba, R Semba, I K Takeuchi, K Kat. Age-related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: a comparison to those of nerve growth factor and neurotrophin-3. Neuroscience research. vol 31. issue 3. 1999-02-05. PMID:9809668. |
a strong staining with antibodies specific for bdnf was observed in the hilus of the dentate gyrus in the hippocampus from aged rats. |
1999-02-05 |
2023-08-12 |
mouse |
| R Katoh-Semba, R Semba, I K Takeuchi, K Kat. Age-related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: a comparison to those of nerve growth factor and neurotrophin-3. Neuroscience research. vol 31. issue 3. 1999-02-05. PMID:9809668. |
patterns of age-related changes in the level of bdnf in the mouse hippocampus. |
1999-02-05 |
2023-08-12 |
mouse |
| R Katoh-Semba, R Semba, I K Takeuchi, K Kat. Age-related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: a comparison to those of nerve growth factor and neurotrophin-3. Neuroscience research. vol 31. issue 3. 1999-02-05. PMID:9809668. |
in senescence-accelerated mice with memory disturbances, no marked increases in levels of ngf and bdnf in the hippocampus and in the level of nt-3 in the cerebral cortex were found. |
1999-02-05 |
2023-08-12 |
mouse |
| R Katoh-Semba, R Semba, I K Takeuchi, K Kat. Age-related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: a comparison to those of nerve growth factor and neurotrophin-3. Neuroscience research. vol 31. issue 3. 1999-02-05. PMID:9809668. |
thus, increases in levels of bdnf and nt-3 occurred in the murine hippocampus and cerebral cortex, respectively, during normal aging, but not during aging of mice with pathological changes. |
1999-02-05 |
2023-08-12 |
mouse |
| F Boris-Möller, F Kamme, T Wieloc. The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat. Brain research. Molecular brain research. vol 63. issue 1. 1999-01-21. PMID:9838092. |
the expression of the mrnas of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin 3 (nt3) and the neurotrophin receptor, trkb, was studied in the rat hippocampus by in situ hybridization following normothermic (37 degreesc) and protective hypothermic (33 degreesc) transient cerebral ischemia of 15 min duration. |
1999-01-21 |
2023-08-12 |
rat |
| F Boris-Möller, F Kamme, T Wieloc. The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat. Brain research. Molecular brain research. vol 63. issue 1. 1999-01-21. PMID:9838092. |
we conclude that, the expressions of ngf, bdnf, nt3 or trkb mrna in ischemia-sensitive hippocampal subregions are not increased by protective hypothermia. |
1999-01-21 |
2023-08-12 |
rat |
| M J Schaaf, J de Jong, E R de Kloet, E Vreugdenhi. Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain research. vol 813. issue 1. 1999-01-20. PMID:9824681. |
downregulation of bdnf mrna and protein in the rat hippocampus by corticosterone. |
1999-01-20 |
2023-08-12 |
rat |
| M J Schaaf, J de Jong, E R de Kloet, E Vreugdenhi. Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain research. vol 813. issue 1. 1999-01-20. PMID:9824681. |
previously, we showed that corticosterone regulates bdnf mrna levels in the hippocampus. |
1999-01-20 |
2023-08-12 |
rat |
| M J Schaaf, J de Jong, E R de Kloet, E Vreugdenhi. Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain research. vol 813. issue 1. 1999-01-20. PMID:9824681. |
at 3, 6, 12 and 24 h after administration bdnf and trkb mrna levels in hippocampal subfields were measured by in situ hybridization. |
1999-01-20 |
2023-08-12 |
rat |
| M J Schaaf, J de Jong, E R de Kloet, E Vreugdenhi. Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain research. vol 813. issue 1. 1999-01-20. PMID:9824681. |
in conclusion, we have found a transient, dose-dependent decrease in bdnf mrna and protein in the hippocampus, which may underly changes in neuronal plasticity in the hippocampus after short-term changes in corticosterone concentrations. |
1999-01-20 |
2023-08-12 |
rat |
| R S Duman, V A Vaidy. Molecular and cellular actions of chronic electroconvulsive seizures. The journal of ECT. vol 14. issue 3. 1998-12-23. PMID:9773357. |
chronic ecs is also reported to induce sprouting of hippocampal neurons, and studies in bdnf mutant mice indicated that this sprouting is partially dependent on upregulation of bdnf. |
1998-12-23 |
2023-08-12 |
mouse |
| R S Duman, V A Vaidy. Molecular and cellular actions of chronic electroconvulsive seizures. The journal of ECT. vol 14. issue 3. 1998-12-23. PMID:9773357. |
increased expression of bdnf and sprouting could also contribute to the altered electrophysiologic properties of hippocampal neurons. |
1998-12-23 |
2023-08-12 |
mouse |
| V Lessman. Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS. General pharmacology. vol 31. issue 5. 1998-12-23. PMID:9809461. |
the neurotrophins ngf, bdnf, and nt-3 and the bdnf and nt-3 selective receptors (trkb, trkc) are expressed at high levels in neurons of the basal forebrain, the hippocampus, and the neocortex of the mammalian brain. |
1998-12-23 |
2023-08-12 |
Not clear |
| V Lessman. Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS. General pharmacology. vol 31. issue 5. 1998-12-23. PMID:9809461. |
in addition, long-term potentiation (a potential cellular correlate for learning and memory formation in mammals) in the rodent hippocampus depends on endogenous supply of neurons with bdnf. |
1998-12-23 |
2023-08-12 |
Not clear |
| T Tsukahara, K Iihara, N Hashimoto, T Nishijima, T Taniguch. Increases in levels of brain-derived neurotrophic factor mRNA and its promoters after transient forebrain ischemia in the rat brain. Neurochemistry international. vol 33. issue 2. 1998-12-11. PMID:9761465. |
the alterations in bdnf gene expression in the hippocampus and in the cerebral cortex were examined by in situ hybridization using a mouse bdnf cdna probe and cdna probes including exon-specific promoters. |
1998-12-11 |
2023-08-12 |
mouse |