| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Marty, B Onténient. BDNF and NT-4 differentiate two pathways in the modulation of neuropeptide protein levels in postnatal hippocampal interneurons. The European journal of neuroscience. vol 11. issue 5. 1999-05-26. PMID:10215918. |
these results indicate that although neuronal activity plays a major role in determining neuropeptide protein levels in postnatal hippocampal interneurons, its effects on different neuropeptides might be exerted through different mechanisms, with or without the mediation of bdnf or nt-4. |
1999-05-26 |
2023-08-12 |
rat |
| S J French, T Humby, C H Horner, M V Sofroniew, M Rattra. Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine. Brain research. Molecular brain research. vol 67. issue 1. 1999-05-21. PMID:10101239. |
pilocarpine caused a transient increase in hippocampal brain-derived neurotrophic factor (bdnf) levels, with carbachol and nicotine showing the same trend. |
1999-05-21 |
2023-08-12 |
Not clear |
| D R Lee, R Semba, H Kondo, S Goto, K Nakan. Decrease in the levels of NGF and BDNF in brains of mice fed a tryptophan-deficient diet. Bioscience, biotechnology, and biochemistry. vol 63. issue 2. 1999-05-20. PMID:10192916. |
feeding the mice a trp-deficient diet for 2 weeks significantly decreased in the hippocampal level of ngf but not those of bdnf and nt-3, as compared with feeding an adequate trp diet. |
1999-05-20 |
2023-08-12 |
mouse |
| A K Shetty, D A Turne. Neurite outgrowth from progeny of epidermal growth factor-responsive hippocampal stem cells is significantly less robust than from fetal hippocampal cells following grafting onto organotypic hippocampal slice cultures: effect of brain-derived neurotrophic factor. Journal of neurobiology. vol 38. issue 3. 1999-05-07. PMID:10022581. |
application of brain-derived neurotrophic factor (bdnf) (5 ng in 0.5 microl) to slices on day 1 after grafting significantly enhanced neurite outgrowth from neurosphere cells, but overall neurite outgrowth from neurosphere cells remained decreased compared to that from fetal hippocampal cells. |
1999-05-07 |
2023-08-12 |
mouse |
| V A Vaidya, R M Terwilliger, R S Duma. Role of 5-HT2A receptors in the stress-induced down-regulation of brain-derived neurotrophic factor expression in rat hippocampus. Neuroscience letters. vol 262. issue 1. 1999-05-06. PMID:10076858. |
immobilization stress decreases the expression of bdnf mrna in the rat hippocampus, and this effect could contribute to the atrophy of hippocampal neurons. |
1999-05-06 |
2023-08-12 |
rat |
| V A Vaidya, R M Terwilliger, R S Duma. Role of 5-HT2A receptors in the stress-induced down-regulation of brain-derived neurotrophic factor expression in rat hippocampus. Neuroscience letters. vol 262. issue 1. 1999-05-06. PMID:10076858. |
the results demonstrate that 5-ht2a receptors mediate, at least in part, the stress-induced down-regulation of bdnf expression in the rat hippocampus. |
1999-05-06 |
2023-08-12 |
rat |
| S Morinobu, K Fujimaki, N Okuyama, M Takahashi, R S Duma. Stimulation of adenylyl cyclase and induction of brain-derived neurotrophic factor and TrkB mRNA by NKH477, a novel and potent forskolin derivative. Journal of neurochemistry. vol 72. issue 5. 1999-05-06. PMID:10217303. |
in addition, administration of nkh477 at the 1 mg/kg dose increased the expression of bdnf and trkb mrna in frontal cortex and hippocampus. |
1999-05-06 |
2023-08-12 |
rat |
| N Belluardo, G Mudò, G Caniglia, M Corsaro, Q Cheng, F Frasca, A Belfiore, D F Condorell. Expression of neurotrophins, GDNF, and their receptors in rat thyroid tissue. Cell and tissue research. vol 295. issue 3. 1999-04-13. PMID:10022966. |
in thyroid tissue the nt-3 mrna level was threefold lower and the nt-4 mrna level sixfold higher than those detected in adult rat hippocampus, while bdnf mrna was undetectable. |
1999-04-13 |
2023-08-12 |
rat |
| S J Mowla, S Pareek, H F Farhadi, K Petrecca, J P Fawcett, N G Seidah, S J Morris, W S Sossin, R A Murph. Differential sorting of nerve growth factor and brain-derived neurotrophic factor in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 6. 1999-04-13. PMID:10066260. |
to determine whether sorting differences are intrinsic to the neurotrophins or reflect differences between cell types, we compared ngf and bdnf processing in cultured hippocampal neurons using a vaccinia virus expression system. |
1999-04-13 |
2023-08-12 |
Not clear |
| S Kinoshita, H Yasuda, N Taniguchi, R Katoh-Semba, H Hatanaka, T Tsumot. Brain-derived neurotrophic factor prevents low-frequency inputs from inducing long-term depression in the developing visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 6. 1999-04-13. PMID:10066265. |
brain-derived neurotrophic factor (bdnf) is reported to enhance synaptic transmission and to play a role in long-term potentiation in hippocampus and neocortex. |
1999-04-13 |
2023-08-12 |
rat |
| E Castrén, B Berninger, A Leingärtner, D Lindhol. Regulation of brain-derived neurotrophic factor mRNA levels in hippocampus by neuronal activity. Progress in brain research. vol 117. 1999-03-11. PMID:9932400. |
we have investigated the pathways through which neuronal activity stimulated by kainic acid regulates bdnf mrna levels in cultured hippocampal neurons and transgenic mice. |
1999-03-11 |
2023-08-12 |
mouse |
| E Castrén, B Berninger, A Leingärtner, D Lindhol. Regulation of brain-derived neurotrophic factor mRNA levels in hippocampus by neuronal activity. Progress in brain research. vol 117. 1999-03-11. PMID:9932400. |
increase in the bdnf mrna levels by kainic acid was not blocked by the protein synthesis inhibitor cycloheximide demonstrating that bdnf is regulated as an immediate early gene in hippocampal neurons. |
1999-03-11 |
2023-08-12 |
mouse |
| J P Kesslak, V So, J Choi, C W Cotman, F Gomez-Pinill. Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance? Behavioral neuroscience. vol 112. issue 4. 1999-03-09. PMID:9733207. |
in this study, rats trained to locate a submerged platform in a water maze had elevated levels of bdnf messenger ribonucleic acid (mrna) in the hippocampus (p < .05), a structure associated with spatial memory. |
1999-03-09 |
2023-08-12 |
rat |
| D Wu, W M Pardridg. Neuroprotection with noninvasive neurotrophin delivery to the brain. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 1. 1999-03-01. PMID:9874805. |
brain-derived neurotrophic factor (bdnf) is neuroprotective in the ischemic hippocampus if the neurotrophin is injected directly into the brain. |
1999-03-01 |
2023-08-12 |
rat |
| W Tokuyama, T Hashimoto, Y X Li, H Okuno, Y Miyashit. Highest trkB mRNA expression in the entorhinal cortex among hippocampal subregions in the adult rat: contrasting pattern with BDNF mRNA expression. Brain research. Molecular brain research. vol 62. issue 2. 1999-02-18. PMID:9813329. |
highest trkb mrna expression in the entorhinal cortex among hippocampal subregions in the adult rat: contrasting pattern with bdnf mrna expression. |
1999-02-18 |
2023-08-12 |
rat |
| W Tokuyama, T Hashimoto, Y X Li, H Okuno, Y Miyashit. Highest trkB mRNA expression in the entorhinal cortex among hippocampal subregions in the adult rat: contrasting pattern with BDNF mRNA expression. Brain research. Molecular brain research. vol 62. issue 2. 1999-02-18. PMID:9813329. |
brain-derived neurotrophic factor (bdnf) and its receptor, trkb, regulate synaptic functions in the hippocampus of the adult rodent. |
1999-02-18 |
2023-08-12 |
rat |
| W Tokuyama, T Hashimoto, Y X Li, H Okuno, Y Miyashit. Highest trkB mRNA expression in the entorhinal cortex among hippocampal subregions in the adult rat: contrasting pattern with BDNF mRNA expression. Brain research. Molecular brain research. vol 62. issue 2. 1999-02-18. PMID:9813329. |
in previous studies, in situ hybridization methods have been used to evaluate regional differences in bdnf and trkb mrna expression levels in hippocampal subregions. |
1999-02-18 |
2023-08-12 |
rat |
| W Tokuyama, T Hashimoto, Y X Li, H Okuno, Y Miyashit. Highest trkB mRNA expression in the entorhinal cortex among hippocampal subregions in the adult rat: contrasting pattern with BDNF mRNA expression. Brain research. Molecular brain research. vol 62. issue 2. 1999-02-18. PMID:9813329. |
the expression level of bdnf mrna was highest in the dg among the hippocampal subregions and low in the entorhinal cortex and the ca1, whereas the trkb fl mrna expression level was highest in the entorhinal cortex, low in the dg and lowest in the ca3. |
1999-02-18 |
2023-08-12 |
rat |
| S D Croll, N Y Ip, R M Lindsay, S J Wiegan. Expression of BDNF and trkB as a function of age and cognitive performance. Brain research. vol 812. issue 1-2. 1999-02-10. PMID:9813325. |
the expression of the neurotrophic factor bdnf increases during learning-related events and is decreased in the hippocampus of alzheimer's disease patients, suggesting that it plays a role in learning, memory, and/or age-related memory deficits. |
1999-02-10 |
2023-08-12 |
rat |
| M Frerking, R C Malenka, R A Nicol. Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus. Journal of neurophysiology. vol 80. issue 6. 1999-02-10. PMID:9862938. |
brain-derived neurotrophic factor (bdnf) modulates inhibitory, but not excitatory, transmission in the ca1 region of the hippocampus. |
1999-02-10 |
2023-08-12 |
Not clear |