| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F J Rubio, Z Kokaia, A del Arco, M I García-Simón, E Y Snyder, O Lindvall, J Satrústegui, A Martínez-Serran. BDNF gene transfer to the mammalian brain using CNS-derived neural precursors. Gene therapy. vol 6. issue 11. 2000-02-24. PMID:10602381. |
conversely, and ruling out unspecific effects, expression of an antisense version of bdnf resulted in compromised survival of cerebellum-derived cells, and in a lethal phenotype in hippocampal progenitors. |
2000-02-24 |
2023-08-12 |
rat |
| D Han, K Yamada, K Senzaki, H Xiong, H Nawa, T Nabeshim. Involvement of nitric oxide in pentylenetetrazole-induced kindling in rats. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646532. |
a significant increase in bdnf levels was observed in the hippocampus of the kindled rats, which returned to the control levels following seizures induced by ptz. |
2000-02-10 |
2023-08-12 |
rat |
| D Han, K Yamada, K Senzaki, H Xiong, H Nawa, T Nabeshim. Involvement of nitric oxide in pentylenetetrazole-induced kindling in rats. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646532. |
7-ni reduced the hippocampal bdnf levels in control rats and suppressed the increase of bdnf levels in the kindled rats. |
2000-02-10 |
2023-08-12 |
rat |
| L A Mamounas, C A Altar, M E Blue, D R Kaplan, L Tessarollo, W E Lyon. BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 2. 2000-02-09. PMID:10632606. |
bdnf also encouraged the regrowth of the 5-ht plexus in the hippocampus, but only in those lamina where 5-ht axons normally ramify. |
2000-02-09 |
2023-08-12 |
rat |
| K Fujimaki, S Morinobu, R S Duma. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 1. 2000-01-28. PMID:10633490. |
administration of a camp phosphodiesterase 4 inhibitor enhances antidepressant-induction of bdnf mrna in rat hippocampus. |
2000-01-28 |
2023-08-12 |
rat |
| K Fujimaki, S Morinobu, R S Duma. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 1. 2000-01-28. PMID:10633490. |
coadministration of rolipram or ro 20-1724 with an antidepressant (either desipramine or org 4428) for 21 d resulted in a significant induction of bdnf mrna in hippocampus relative to administration of vehicle. |
2000-01-28 |
2023-08-12 |
rat |
| K Fujimaki, S Morinobu, R S Duma. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 1. 2000-01-28. PMID:10633490. |
in situ hybridization analysis demonstrated that the induction of bdnf mrna in response to the repeated coadministration paradigm occurs in the dentate gyrus granule and ca1 and ca3 pyramidal cell layers of hippocampus. |
2000-01-28 |
2023-08-12 |
rat |
| W E Lyons, L A Mamounas, G A Ricaurte, V Coppola, S W Reid, S H Bora, C Wihler, V E Koliatsos, L Tessaroll. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 26. 2000-01-27. PMID:10611369. |
however, young adult bdnf(+/-) mice show a blunted c-fos induction by the specific serotonin releaser-uptake inhibitor dexfenfluramine and alterations in the expression of several 5-ht receptors in the cortex, hippocampus, and hypothalamus. |
2000-01-27 |
2023-08-12 |
mouse |
| J C Lauterborn, G Lynch, P Vanderklish, A Arai, C M Gal. Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 1. 2000-01-27. PMID:10627576. |
finally, intraperitoneal injections of cx546 increased hippocampal bdnf mrna levels in aged rats and middle-aged mice. |
2000-01-27 |
2023-08-12 |
mouse |
| R R Hicks, V B Martin, L Zhang, K B Seroog. Mild experimental brain injury differentially alters the expression of neurotrophin and neurotrophin receptor mRNAs in the hippocampus. Experimental neurology. vol 160. issue 2. 2000-01-14. PMID:10619564. |
we have previously demonstrated that following experimental brain trauma of moderate severity (2.0-2.1 atm), mrna levels of bdnf and its high-affinity receptor, trkb, are increased bilaterally in the hippocampus for several hours, whereas nt-3 mrna expression is decreased. |
2000-01-14 |
2023-08-12 |
rat |
| R R Hicks, V B Martin, L Zhang, K B Seroog. Mild experimental brain injury differentially alters the expression of neurotrophin and neurotrophin receptor mRNAs in the hippocampus. Experimental neurology. vol 160. issue 2. 2000-01-14. PMID:10619564. |
in the present study, we used in situ hybridization to compare bdnf, trkb, nt-3, and trkc mrna expression in rat hippocampus at 3 or 6 h after a lateral fluid percussion brain injury (fpi) of mild severity (1.0 atm) to sham-injured controls at equivalent time points. |
2000-01-14 |
2023-08-12 |
rat |
| R R Hicks, V B Martin, L Zhang, K B Seroog. Mild experimental brain injury differentially alters the expression of neurotrophin and neurotrophin receptor mRNAs in the hippocampus. Experimental neurology. vol 160. issue 2. 2000-01-14. PMID:10619564. |
mild fpi induced significant increases in hybridization levels for bdnf and trkb mrnas, and a decrease in nt-3 mrna in the hippocampus. |
2000-01-14 |
2023-08-12 |
rat |
| N C Berchtold, H S Oliff, P Isackson, C W Cotma. Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript. Brain research. Molecular brain research. vol 71. issue 1. 1999-12-22. PMID:10407182. |
hippocampal bdnf mrna shows a diurnal regulation, primarily in the exon iii transcript. |
1999-12-22 |
2023-08-12 |
rat |
| N C Berchtold, H S Oliff, P Isackson, C W Cotma. Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript. Brain research. Molecular brain research. vol 71. issue 1. 1999-12-22. PMID:10407182. |
endogenous expression levels of brain-derived neurotrophic factor (bdnf) mrna were assessed using in situ hybridization to investigate whether there is a natural diurnal fluctuation in bdnf mrna expression in the hippocampus of rats housed with a normal (12:12 h) light/dark cycle. |
1999-12-22 |
2023-08-12 |
rat |
| N C Berchtold, H S Oliff, P Isackson, C W Cotma. Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript. Brain research. Molecular brain research. vol 71. issue 1. 1999-12-22. PMID:10407182. |
bdnf expression was increased during lights out (dark-cycle) to 134%-158% of light-cycle levels in hippocampal regions ca1, ca3, and hilus. |
1999-12-22 |
2023-08-12 |
rat |
| N C Berchtold, H S Oliff, P Isackson, C W Cotma. Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript. Brain research. Molecular brain research. vol 71. issue 1. 1999-12-22. PMID:10407182. |
in addition to exon iii, dark-cycle exon ii mrna levels were elevated in all hippocampal subfields, to 140-180% of light-cycle levels, suggesting that the endogenous fluctuation in bdnf expression results predominantly from activation of the promoters linked to exons ii and iii. |
1999-12-22 |
2023-08-12 |
rat |
| T Numakawa, N Takei, S Yamagishi, N Sakai, H Hatanak. Neurotrophin-elicited short-term glutamate release from cultured cerebellar granule neurons. Brain research. vol 842. issue 2. 1999-12-21. PMID:10526139. |
rapid and transient glutamate and aspartate releases induced by bdnf were observed from cultured cortical, hippocampal, striatal and cerebellar neurons. |
1999-12-21 |
2023-08-12 |
Not clear |
| A Nitta, M Ito, H Fukumitsu, M Ohmiya, H Ito, A Sometani, H Nomoto, Y Furukawa, S Furukaw. 4-methylcatechol increases brain-derived neurotrophic factor content and mRNA expression in cultured brain cells and in rat brain in vivo. The Journal of pharmacology and experimental therapeutics. vol 291. issue 3. 1999-12-20. PMID:10565852. |
first, we found that ventricularly administered 4-mc facilitated an increase in the bdnf content in the cerebral cortex and hippocampus in association with its diffusion into the brain parenchyma. |
1999-12-20 |
2023-08-12 |
rat |
| S D Croll, C R Chesnutt, N A Greene, R M Lindsay, S J Wiegan. Peptide immunoreactivity in aged rat cortex and hippocampus as a function of memory and BDNF infusion. Pharmacology, biochemistry, and behavior. vol 64. issue 3. 1999-12-13. PMID:10548280. |
peptide immunoreactivity in aged rat cortex and hippocampus as a function of memory and bdnf infusion. |
1999-12-13 |
2023-08-12 |
rat |
| S D Croll, C R Chesnutt, N A Greene, R M Lindsay, S J Wiegan. Peptide immunoreactivity in aged rat cortex and hippocampus as a function of memory and BDNF infusion. Pharmacology, biochemistry, and behavior. vol 64. issue 3. 1999-12-13. PMID:10548280. |
brain-derived neurotrophic factor (bdnf) modulates neuropeptide levels in hippocampus and cortex of young adult rats. |
1999-12-13 |
2023-08-12 |
rat |