| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Skup, J Czarkowska-Bauch, A Dwornik, M Macias, D Sulejczak, M Wiate. Locomotion induces changes in Trk B receptors in small diameter cells of the spinal cord. Acta neurobiologiae experimentalis. vol 60. issue 3. 2000-10-19. PMID:11016079. |
physical exercise increases bdnf neurotrophin gene expression in the rat hippocampus (4). |
2000-10-19 |
2023-08-12 |
rat |
| B Xu, W Gottschalk, A Chow, R I Wilson, E Schnell, K Zang, D Wang, R A Nicoll, B Lu, L F Reichard. The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995833. |
the neurotrophin bdnf has been shown to modulate long-term potentiation (ltp) at schaffer collateral-ca1 hippocampal synapses. |
2000-10-18 |
2023-08-12 |
mouse |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
the radial arm maze training resulted in a significant increase in the bdnf mrna expression in the hippocampus, although the expression in the frontal cortex did not change. |
2000-10-18 |
2023-08-12 |
rat |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
when spatial learning was inhibited by treatment with 7-nitroindazole, an inhibitor of brain nitric oxide synthase, the increase in the hippocampal bdnf mrna did not occur. |
2000-10-18 |
2023-08-12 |
rat |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
treatment with antisense, but not sense, bdnf oligonucleotide was associated with a significant reduction of bdnf mrna and protein levels in the hippocampus. |
2000-10-18 |
2023-08-12 |
rat |
| A M Lindén, J Väisänen, M Lakso, H Nawa, G Wong, E Castré. Expression of neurotrophins BDNF and NT-3, and their receptors in rat brain after administration of antipsychotic and psychotrophic agents. Journal of molecular neuroscience : MN. vol 14. issue 1-2. 2000-10-17. PMID:10854034. |
finally, we confirmed that the effects of mk-801 on bdnf mrna were reflected in the respective changes in bdnf protein levels: mk-801 significantly increased anti-bdnf reactivity in the entorhinal cortex (126 +/- 7% of control) while concomitantly decreasing in the hippocampus (71 +/- 2% of control). |
2000-10-17 |
2023-08-12 |
rat |
| S Reibel, Y Larmet, J Carnahan, C Marescaux, A Depauli. Endogenous control of hippocampal epileptogenesis: a molecular cascade involving brain-derived neurotrophic factor and neuropeptide Y. Epilepsia. vol 41 Suppl 6. 2000-10-17. PMID:10999534. |
seizures increase the expression of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2000-10-17 |
2023-08-12 |
Not clear |
| M Sitcoske O'Shea, J B Rosen, R M Post, S R Weis. Specific amygdaloid nuclei are involved in suppression or propagation of epileptiform activity during transition stage between oral automatisms and generalized clonic seizures. Brain research. vol 873. issue 1. 2000-10-12. PMID:10915805. |
the results demonstrate that: (1) the threshold to elicit an afterdischarge from the bl was lower than that of either the medial (cem) or lateral (cel) subdivisions of the ce, which did not differ from each other; (2) the patterns of mrna expression for c-fos, ngfi-a and bdnf were highly similar to each other when the stimulation site was the bl or the cel, and included mainly limbic cortical and subcortical areas ipsilateral to the electrode; (3) c-fos was the only probe to be expressed in the contralateral hemisphere following the first motor seizure, and the pattern of its expression reflected a subset of structures recruited in the ipsilateral hemisphere including the claustrum, insular and perirhinal cortices; (4) unexpectedly, stimulation of the cem elicited seizures and afterdischarges of shorter duration than those evoked by stimulation of the bl or cel, and failed to increase mrna expression for any of the probes in the hippocampus or in the contralateral hemisphere. |
2000-10-12 |
2023-08-12 |
rat |
| J Du, L Feng, F Yang, B L. Activity- and Ca(2+)-dependent modulation of surface expression of brain-derived neurotrophic factor receptors in hippocampal neurons. The Journal of cell biology. vol 150. issue 6. 2000-10-12. PMID:10995446. |
here we report that the number of bdnf receptor trkb on the surface of hippocampal neurons can be enhanced by high frequency neuronal activity and synaptic transmission, and this effect is mediated by ca(2+) influx. |
2000-10-12 |
2023-08-12 |
Not clear |
| L Zhang, H S Dhillon, S Barron, R R Hicks1, R M Prasad, K B Seroog. Effects of chronic ethanol administration on expression of BDNF and trkB mRNAs in rat hippocampus after experimental brain injury. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925157. |
effects of chronic ethanol administration on expression of bdnf and trkb mrnas in rat hippocampus after experimental brain injury. |
2000-10-04 |
2023-08-12 |
rat |
| L Zhang, H S Dhillon, S Barron, R R Hicks1, R M Prasad, K B Seroog. Effects of chronic ethanol administration on expression of BDNF and trkB mRNAs in rat hippocampus after experimental brain injury. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925157. |
in the present study, we examined the effects of 6 weeks of chronic ethanol administration on lateral fluid percussion (fp) brain injury-induced alterations in expression of mrnas for the neurotrophin brain-derived neurotrophic factor (bdnf) and its high affinity receptor, trkb, in rat hippocampus. |
2000-10-04 |
2023-08-12 |
rat |
| L Zhang, H S Dhillon, S Barron, R R Hicks1, R M Prasad, K B Seroog. Effects of chronic ethanol administration on expression of BDNF and trkB mRNAs in rat hippocampus after experimental brain injury. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925157. |
in both the control- (pair-fed isocaloric sucrose) diet and the chronic ethanol-diet groups, unilateral fp brain injury induced a bilateral increase in levels of both bdnf and trkb mrnas in the dentate gyrus granule cell layer, and of bdnf mrna in hippocampal region ca3. |
2000-10-04 |
2023-08-12 |
rat |
| S A Nanda, K J Mac. Seizures and sensory stimulation result in different patterns of brain derived neurotrophic factor protein expression in the barrel cortex and hippocampus. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891580. |
in order to investigate the activity-dependent regulation of the bdnf gene, bdnf expression was examined within the rat somatosensory cortex (ssc) and hippocampus following vibrissae stimulation, kainic acid induced seizure, and pentylenetetrazol (ptz) induced seizure. |
2000-09-25 |
2023-08-12 |
rat |
| S A Nanda, K J Mac. Seizures and sensory stimulation result in different patterns of brain derived neurotrophic factor protein expression in the barrel cortex and hippocampus. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891580. |
both unilateral whisker stimulation (a model of experience dependent plasticity) and kainic acid induced seizure were able to increase the levels of bdnf protein within the ssc and hippocampus. |
2000-09-25 |
2023-08-12 |
rat |
| S A Nanda, K J Mac. Seizures and sensory stimulation result in different patterns of brain derived neurotrophic factor protein expression in the barrel cortex and hippocampus. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891580. |
finally, whisker stimulation resulted in an unexpected increase in bdnf mrna and protein levels within the hippocampus. |
2000-09-25 |
2023-08-12 |
rat |
| T Saarelainen, J A Lukkarinen, S Koponen, O H Gröhn, J Jolkkonen, E Koponen, A Haapasalo, L Alhonen, G Wong, J Koistinaho, R A Kauppinen, E Castré. Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons show increased susceptibility to cortical injury after focal cerebral ischemia. Molecular and cellular neurosciences. vol 16. issue 2. 2000-09-21. PMID:10924253. |
in order to test this hypothesis experimentally, we have produced transgenic mouse lines that overexpress the dominant-negative truncated splice variant of bdnf receptor trkb (trkb.t1) in postnatal cortical and hippocampal neurons. |
2000-09-21 |
2023-08-12 |
mouse |
| B Vollmayr, S Keck, F A Henn, P Schlos. Acute stress decreases serotonin transporter mRNA in the raphe pontis but not in other raphe nuclei of the rat. Neuroscience letters. vol 290. issue 2. 2000-09-21. PMID:10936689. |
acute stress led to a significant decrease of bdnf mrna in the hippocampus and of sert mrna in the raphe pontis, but not in other raphe nuclei investigated. |
2000-09-21 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
corticosterone effects on bdnf expression in the hippocampus. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
in this review, the question is addressed if the corticosterone effects on memory processes are mediated by alterations in the expression of the neurotrophin brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
first, studies are described investigating the effect of corticosterone on bdnf expression in the rat hippocampus. |
2000-09-15 |
2023-08-12 |
rat |