| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
we have shown previously that chronic infusion of bdnf in the hippocampus induces a long-term delay in hippocampal kindling progression. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
although bdnf has been shown to enhance the excitability of this structure upon acute application, long-term transcriptional regulations leading to increased inhibition within the hippocampus may account for its suppressive effects on epileptogenesis. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
therefore, the long-term consequences of a 7-day chronic intrahippocampal infusion of bdnf (12 microg/day) were investigated up to 2 weeks after the end of the infusion, on the expression of neurotransmitters contained in inhibitory hippocampal interneurons and which display anti-epileptic properties. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
conversely, bdnf induces a long-lasting increase of neuropeptide y (npy) in the hippocampus, measured by immunohistochemistry and radioimmunoassay, outlasting the end of the infusion by at least 7 days. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
the enduring increase of neuropeptide y expression induced by bdnf in the hippocampus suggests that this neurotrophin can trigger long-term genomic effects, which may contribute to the neuroplasticity of this structure, in particular during epileptogenesis. |
2000-05-25 |
2023-08-12 |
rat |
| F Asztely, M Kokaia, K Olofsdotter, U Ortegren, O Lindval. Afferent-specific modulation of short-term synaptic plasticity by neurotrophins in dentate gyrus. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712646. |
using field recordings and whole-cell patch-clamp recordings in hippocampal slices, we found that paired-pulse (pp) depression at mpp-granule cell synapses was impaired in bdnf knock-out (+/-) mice, but pp facilitation at lpp synapses to the same cells was not impaired. |
2000-05-25 |
2023-08-12 |
mouse |
| K Heese, U Otten, P Mathivet, M Raiteri, C Marescaux, R Bernascon. GABA(B) receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats. Neuropharmacology. vol 39. issue 3. 2000-05-16. PMID:10698011. |
in this study we show that single, physiologically-active and non-convulsive doses of the three gaba(b) receptor antagonists cgp 36742, cgp 56433a and cgp 56999a increase ngf and bdnf mrna levels by 200-400% and protein levels by 200-250% in rat neocortex, hippocampus as well as spinal cord. |
2000-05-16 |
2023-08-12 |
rat |
| M J Schaaf, R Duurland, E R de Kloet, E Vreugdenhi. Circadian variation in BDNF mRNA expression in the rat hippocampus. Brain research. Molecular brain research. vol 75. issue 2. 2000-04-21. PMID:10686357. |
circadian variation in bdnf mrna expression in the rat hippocampus. |
2000-04-21 |
2023-08-12 |
rat |
| M J Schaaf, R Duurland, E R de Kloet, E Vreugdenhi. Circadian variation in BDNF mRNA expression in the rat hippocampus. Brain research. Molecular brain research. vol 75. issue 2. 2000-04-21. PMID:10686357. |
bdnf mrna levels in the hippocampus were studied during the circadian cycle by in situ hybridization. |
2000-04-21 |
2023-08-12 |
rat |
| G Fan, C Egles, Y Sun, L Minichiello, J J Renger, R Klein, G Liu, R Jaenisc. Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities. Nature neuroscience. vol 3. issue 4. 2000-04-21. PMID:10725924. |
although the bdnfnt4-ki/nt4-ki and wild-type bdnf+/+ alleles yielded similar levels of nt4 and bdnf proteins, nt4 supported more sensory neurons than bdnf and promoted functional synapse formation in cultured hippocampal neurons. |
2000-04-21 |
2023-08-12 |
mouse |
| C Aoki, K Wu, A Elste, G w Len, S y Lin, G McAuliffe, I B Blac. Localization of brain-derived neurotrophic factor and TrkB receptors to postsynaptic densities of adult rat cerebral cortex. Journal of neuroscience research. vol 59. issue 3. 2000-03-16. PMID:10679783. |
brain-derived neurotrophic factor (bdnf) rapidly increases synaptic transmission in hippocampal neurons, and enhances long-term potentiation (ltp), a cellular and molecular model of learning and memory. |
2000-03-16 |
2023-08-12 |
rat |
| F J Rubio, Z Kokaia, A del Arco, M I García-Simón, E Y Snyder, O Lindvall, J Satrústegui, A Martínez-Serran. BDNF gene transfer to the mammalian brain using CNS-derived neural precursors. Gene therapy. vol 6. issue 11. 2000-02-24. PMID:10602381. |
conversely, and ruling out unspecific effects, expression of an antisense version of bdnf resulted in compromised survival of cerebellum-derived cells, and in a lethal phenotype in hippocampal progenitors. |
2000-02-24 |
2023-08-12 |
rat |
| D Han, K Yamada, K Senzaki, H Xiong, H Nawa, T Nabeshim. Involvement of nitric oxide in pentylenetetrazole-induced kindling in rats. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646532. |
a significant increase in bdnf levels was observed in the hippocampus of the kindled rats, which returned to the control levels following seizures induced by ptz. |
2000-02-10 |
2023-08-12 |
rat |
| D Han, K Yamada, K Senzaki, H Xiong, H Nawa, T Nabeshim. Involvement of nitric oxide in pentylenetetrazole-induced kindling in rats. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646532. |
7-ni reduced the hippocampal bdnf levels in control rats and suppressed the increase of bdnf levels in the kindled rats. |
2000-02-10 |
2023-08-12 |
rat |
| L A Mamounas, C A Altar, M E Blue, D R Kaplan, L Tessarollo, W E Lyon. BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 2. 2000-02-09. PMID:10632606. |
bdnf also encouraged the regrowth of the 5-ht plexus in the hippocampus, but only in those lamina where 5-ht axons normally ramify. |
2000-02-09 |
2023-08-12 |
rat |
| K Fujimaki, S Morinobu, R S Duma. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 1. 2000-01-28. PMID:10633490. |
administration of a camp phosphodiesterase 4 inhibitor enhances antidepressant-induction of bdnf mrna in rat hippocampus. |
2000-01-28 |
2023-08-12 |
rat |
| K Fujimaki, S Morinobu, R S Duma. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 1. 2000-01-28. PMID:10633490. |
coadministration of rolipram or ro 20-1724 with an antidepressant (either desipramine or org 4428) for 21 d resulted in a significant induction of bdnf mrna in hippocampus relative to administration of vehicle. |
2000-01-28 |
2023-08-12 |
rat |
| K Fujimaki, S Morinobu, R S Duma. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 1. 2000-01-28. PMID:10633490. |
in situ hybridization analysis demonstrated that the induction of bdnf mrna in response to the repeated coadministration paradigm occurs in the dentate gyrus granule and ca1 and ca3 pyramidal cell layers of hippocampus. |
2000-01-28 |
2023-08-12 |
rat |
| W E Lyons, L A Mamounas, G A Ricaurte, V Coppola, S W Reid, S H Bora, C Wihler, V E Koliatsos, L Tessaroll. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 26. 2000-01-27. PMID:10611369. |
however, young adult bdnf(+/-) mice show a blunted c-fos induction by the specific serotonin releaser-uptake inhibitor dexfenfluramine and alterations in the expression of several 5-ht receptors in the cortex, hippocampus, and hypothalamus. |
2000-01-27 |
2023-08-12 |
mouse |
| J C Lauterborn, G Lynch, P Vanderklish, A Arai, C M Gal. Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 1. 2000-01-27. PMID:10627576. |
finally, intraperitoneal injections of cx546 increased hippocampal bdnf mrna levels in aged rats and middle-aged mice. |
2000-01-27 |
2023-08-12 |
mouse |