| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E S Levine, J E Kol. Brain-derived neurotrophic factor increases activity of NR2B-containing N-methyl-D-aspartate receptors in excised patches from hippocampal neurons. Journal of neuroscience research. vol 62. issue 3. 2000-12-22. PMID:11054804. |
in the present study, we used excised membrane patches from cultured hippocampal neurons to determine whether bdnf directly modulates postsynaptic nmda receptor activity. |
2000-12-22 |
2023-08-12 |
Not clear |
| P Baldelli, P E Forni, E Carbon. BDNF, NT-3 and NGF induce distinct new Ca2+ channel synthesis in developing hippocampal neurons. The European journal of neuroscience. vol 12. issue 11. 2000-12-22. PMID:11069598. |
bdnf, nt-3 and ngf induce distinct new ca2+ channel synthesis in developing hippocampal neurons. |
2000-12-22 |
2023-08-12 |
Not clear |
| P Baldelli, P E Forni, E Carbon. BDNF, NT-3 and NGF induce distinct new Ca2+ channel synthesis in developing hippocampal neurons. The European journal of neuroscience. vol 12. issue 11. 2000-12-22. PMID:11069598. |
here we show that bdnf, ngf and nt-3 (10-100 ng/ml) exhibit a selective long-term up-regulation of voltage-gated ca2+ current densities in developing hippocampal neurons of 6-20 days in culture. |
2000-12-22 |
2023-08-12 |
Not clear |
| H Kawakami, A Nitta, Y Matsuyama, M Kamiya, K Satake, K Sato, K Kondou, H Iwata, S Furukaw. Increase in neurotrophin-3 expression followed by Purkinje cell degeneration in the adult rat cerebellum after spinal cord transection. Journal of neuroscience research. vol 62. issue 5. 2000-12-22. PMID:11104504. |
changes in brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) contents following thoracic spinal cord transection were investigated in the cerebral cortex, hippocampus, and cerebellum of rats. |
2000-12-22 |
2023-08-12 |
rat |
| H Sei, D Saitoh, K Yamamoto, K Morita, Y Morit. Differential effect of short-term REM sleep deprivation on NGF and BDNF protein levels in the rat brain. Brain research. vol 877. issue 2. 2000-12-14. PMID:10986357. |
we therefore investigated the effects of selective rem sleep deprivation (rsd) on ngf and bdnf proteins in the hippocampus, cerebellum and brainstem in the rat. |
2000-12-14 |
2023-08-12 |
rat |
| H Sei, D Saitoh, K Yamamoto, K Morita, Y Morit. Differential effect of short-term REM sleep deprivation on NGF and BDNF protein levels in the rat brain. Brain research. vol 877. issue 2. 2000-12-14. PMID:10986357. |
conversely, in the hippocampus, ngf was significantly decreased while bdnf was not changed. |
2000-12-14 |
2023-08-12 |
rat |
| M G Murer, Q Yan, R Raisman-Vozar. Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease. Progress in neurobiology. vol 63. issue 1. 2000-12-07. PMID:11040419. |
bdnf has been found to promote survival of all major neuronal types affected in alzheimer's disease and parkinson's disease, like hippocampal and neocortical neurons, cholinergic septal and basal forebrain neurons, and nigral dopaminergic neurons. |
2000-12-07 |
2023-08-12 |
human |
| D D Murphy, M Sega. Progesterone prevents estradiol-induced dendritic spine formation in cultured hippocampal neurons. Neuroendocrinology. vol 72. issue 3. 2000-11-21. PMID:11025407. |
estradiol has been shown to cause an increase in dendritic spine density in cultured hippocampal neurons, an effect mediated by downregulation of brain-derived neurotrophic factor (bdnf) and glutamic acid decarboxylase (gad), and the subsequent phosphorylation of camp response element binding protein (creb) in response to enhanced activity levels. |
2000-11-21 |
2023-08-12 |
Not clear |
| M C Hoene. Role played by sodium in activity-dependent secretion of neurotrophins - revisited. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998093. |
we now report that rapid sodium influx initiated by monensin or ouabain did not induce brain-derived neurotrophic factor (bdnf) secretion from either native hippocampal slices or bdnf-transduced hippocampal neuronal cultures. |
2000-11-07 |
2023-08-12 |
Not clear |
| A C Hansson, A Cintra, N Belluardo, W Sommer, M Bhatnagar, M Bader, D Ganten, K Fux. Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat. The European journal of neuroscience. vol 12. issue 8. 2000-10-19. PMID:10971634. |
gene expression of basic fibroblast growth factor (bfgf) and its high-affinity receptors [fibroblast growth factor receptor subtypes 1-3 (fgf-r1, fgf-r2, fgf-r3)], as well as brain-derived growth factor (bdnf) and neurotrophin-3 (nt-3) was analysed at 4 h after the hormone injection in ca1-ca4 (cornus of ammon areas of the hippocampus) and dentate gyrus of the dorsal hippocampus and in neocortex by means of in situ hybridization. |
2000-10-19 |
2023-08-12 |
rat |
| A C Hansson, A Cintra, N Belluardo, W Sommer, M Bhatnagar, M Bader, D Ganten, K Fux. Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat. The European journal of neuroscience. vol 12. issue 8. 2000-10-19. PMID:10971634. |
fgf-r2 expression in the hippocampus seems to be regulated only by mr, while bdnf expression appears to depend on both receptors. |
2000-10-19 |
2023-08-12 |
rat |
| M Skup, J Czarkowska-Bauch, A Dwornik, M Macias, D Sulejczak, M Wiate. Locomotion induces changes in Trk B receptors in small diameter cells of the spinal cord. Acta neurobiologiae experimentalis. vol 60. issue 3. 2000-10-19. PMID:11016079. |
physical exercise increases bdnf neurotrophin gene expression in the rat hippocampus (4). |
2000-10-19 |
2023-08-12 |
rat |
| B Xu, W Gottschalk, A Chow, R I Wilson, E Schnell, K Zang, D Wang, R A Nicoll, B Lu, L F Reichard. The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995833. |
the neurotrophin bdnf has been shown to modulate long-term potentiation (ltp) at schaffer collateral-ca1 hippocampal synapses. |
2000-10-18 |
2023-08-12 |
mouse |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
the radial arm maze training resulted in a significant increase in the bdnf mrna expression in the hippocampus, although the expression in the frontal cortex did not change. |
2000-10-18 |
2023-08-12 |
rat |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
when spatial learning was inhibited by treatment with 7-nitroindazole, an inhibitor of brain nitric oxide synthase, the increase in the hippocampal bdnf mrna did not occur. |
2000-10-18 |
2023-08-12 |
rat |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
treatment with antisense, but not sense, bdnf oligonucleotide was associated with a significant reduction of bdnf mrna and protein levels in the hippocampus. |
2000-10-18 |
2023-08-12 |
rat |
| A M Lindén, J Väisänen, M Lakso, H Nawa, G Wong, E Castré. Expression of neurotrophins BDNF and NT-3, and their receptors in rat brain after administration of antipsychotic and psychotrophic agents. Journal of molecular neuroscience : MN. vol 14. issue 1-2. 2000-10-17. PMID:10854034. |
finally, we confirmed that the effects of mk-801 on bdnf mrna were reflected in the respective changes in bdnf protein levels: mk-801 significantly increased anti-bdnf reactivity in the entorhinal cortex (126 +/- 7% of control) while concomitantly decreasing in the hippocampus (71 +/- 2% of control). |
2000-10-17 |
2023-08-12 |
rat |
| S Reibel, Y Larmet, J Carnahan, C Marescaux, A Depauli. Endogenous control of hippocampal epileptogenesis: a molecular cascade involving brain-derived neurotrophic factor and neuropeptide Y. Epilepsia. vol 41 Suppl 6. 2000-10-17. PMID:10999534. |
seizures increase the expression of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2000-10-17 |
2023-08-12 |
Not clear |
| M Sitcoske O'Shea, J B Rosen, R M Post, S R Weis. Specific amygdaloid nuclei are involved in suppression or propagation of epileptiform activity during transition stage between oral automatisms and generalized clonic seizures. Brain research. vol 873. issue 1. 2000-10-12. PMID:10915805. |
the results demonstrate that: (1) the threshold to elicit an afterdischarge from the bl was lower than that of either the medial (cem) or lateral (cel) subdivisions of the ce, which did not differ from each other; (2) the patterns of mrna expression for c-fos, ngfi-a and bdnf were highly similar to each other when the stimulation site was the bl or the cel, and included mainly limbic cortical and subcortical areas ipsilateral to the electrode; (3) c-fos was the only probe to be expressed in the contralateral hemisphere following the first motor seizure, and the pattern of its expression reflected a subset of structures recruited in the ipsilateral hemisphere including the claustrum, insular and perirhinal cortices; (4) unexpectedly, stimulation of the cem elicited seizures and afterdischarges of shorter duration than those evoked by stimulation of the bl or cel, and failed to increase mrna expression for any of the probes in the hippocampus or in the contralateral hemisphere. |
2000-10-12 |
2023-08-12 |
rat |
| J Du, L Feng, F Yang, B L. Activity- and Ca(2+)-dependent modulation of surface expression of brain-derived neurotrophic factor receptors in hippocampal neurons. The Journal of cell biology. vol 150. issue 6. 2000-10-12. PMID:10995446. |
here we report that the number of bdnf receptor trkb on the surface of hippocampal neurons can be enhanced by high frequency neuronal activity and synaptic transmission, and this effect is mediated by ca(2+) influx. |
2000-10-12 |
2023-08-12 |
Not clear |