| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W J Tyler, L D Pozzo-Mille. BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 12. 2001-07-12. PMID:11404410. |
in agreement with the hypothesis that an increased docked vesicle density enhances quantal neurotransmitter release, bdnf increased the frequency, but not the amplitude, of ampa receptor-mediated miniature epscs (mepscs) recorded from ca1 pyramidal neurons in hippocampal slices. |
2001-07-12 |
2023-08-12 |
rat |
| Y Liu, C D Fowler, L J Young, Q Yan, T R Insel, Z Wan. Expression and estrogen regulation of brain-derived neurotrophic factor gene and protein in the forebrain of female prairie voles. The Journal of comparative neurology. vol 433. issue 4. 2001-06-28. PMID:11304714. |
ovariectomized prairie voles that were treated with estradiol benzoate had a higher level of bdnf mrna labeling in the dentate gyrus and ca3 region of the hippocampus, as well as in the basolateral nucleus of the amygdala, than did ovariectomized voles that were treated with vehicle. |
2001-06-28 |
2023-08-12 |
rat |
| G Aakalu, W B Smith, N Nguyen, C Jiang, E M Schuma. Dynamic visualization of local protein synthesis in hippocampal neurons. Neuron. vol 30. issue 2. 2001-06-28. PMID:11395009. |
in cultured hippocampal neurons, we show that bdnf, a growth factor involved in synaptic plasticity, stimulates protein synthesis of the reporter in intact, mechanically, or "optically" isolated dendrites. |
2001-06-28 |
2023-08-12 |
Not clear |
| C Collin, C Vicario-Abejon, M E Rubio, R J Wenthold, R D McKay, M Sega. Neurotrophins act at presynaptic terminals to activate synapses among cultured hippocampal neurons. The European journal of neuroscience. vol 13. issue 7. 2001-06-21. PMID:11298787. |
we have recently demonstrated that embryonic e16 hippocampal neurons grown in cultures are unable to form fast synaptic connections unless treated with bdnf or nt-3. |
2001-06-21 |
2023-08-12 |
Not clear |
| I Brünig, S Penschuck, B Berninger, J Benson, J M Fritsch. BDNF reduces miniature inhibitory postsynaptic currents by rapid downregulation of GABA(A) receptor surface expression. The European journal of neuroscience. vol 13. issue 7. 2001-06-21. PMID:11298792. |
using primary cultures of rat hippocampal neurons, we investigated the effects of bdnf on gabaergic miniature inhibitory postsynaptic currents (mipscs) and on the localization of gabaa receptors. |
2001-06-21 |
2023-08-12 |
rat |
| G S Pollock, E Vernon, M E Forbes, Q Yan, Y T Ma, T Hsieh, R Robichon, D O Frost, J E Johnso. Effects of early visual experience and diurnal rhythms on BDNF mRNA and protein levels in the visual system, hippocampus, and cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 11. 2001-06-21. PMID:11356880. |
effects of early visual experience and diurnal rhythms on bdnf mrna and protein levels in the visual system, hippocampus, and cerebellum. |
2001-06-21 |
2023-08-12 |
Not clear |
| G S Pollock, E Vernon, M E Forbes, Q Yan, Y T Ma, T Hsieh, R Robichon, D O Frost, J E Johnso. Effects of early visual experience and diurnal rhythms on BDNF mRNA and protein levels in the visual system, hippocampus, and cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 11. 2001-06-21. PMID:11356880. |
we report that rearing in constant light or dr alters bdnf mrna and protein levels in the retina, superior colliculus (sc), v1, hippocampus (hipp), and cerebellum (cbl), although the changes in mrna and protein are not always correlated. |
2001-06-21 |
2023-08-12 |
Not clear |
| G S Pollock, E Vernon, M E Forbes, Q Yan, Y T Ma, T Hsieh, R Robichon, D O Frost, J E Johnso. Effects of early visual experience and diurnal rhythms on BDNF mRNA and protein levels in the visual system, hippocampus, and cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 11. 2001-06-21. PMID:11356880. |
by contrast, in hipp and cbl, the tissue concentration of bdnf protein is higher during the dark phase. |
2001-06-21 |
2023-08-12 |
Not clear |
| A Russo-Neustadt, T Ha, R Ramirez, J P Kessla. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behavioural brain research. vol 120. issue 1. 2001-05-31. PMID:11173088. |
it has been reported that chronic antidepressant treatment leads to an up-regulation of brain-derived neurotrophic factor (bdnf) mrna levels in the hippocampus, and that physical activity (voluntary running) enhances this effect. |
2001-05-31 |
2023-08-12 |
rat |
| A Russo-Neustadt, T Ha, R Ramirez, J P Kessla. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behavioural brain research. vol 120. issue 1. 2001-05-31. PMID:11173088. |
animals receiving the combined intervention showed an increase in hippocampal bdnf mrna well above baseline. |
2001-05-31 |
2023-08-12 |
rat |
| A Russo-Neustadt, T Ha, R Ramirez, J P Kessla. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behavioural brain research. vol 120. issue 1. 2001-05-31. PMID:11173088. |
enhanced swimming time correlated with increased levels of bdnf mrna in one hippocampal sub-region (ca4-hilus). |
2001-05-31 |
2023-08-12 |
rat |
| M Zocher, S Czub, J Schulte-Mönting, J C de La Torre, C Saude. Alterations in neurotrophin and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection. Journal of neurovirology. vol 6. issue 6. 2001-05-17. PMID:11175319. |
we have used rnase protection assay to measure mrna levels of the neurotrophins nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), and neurotrophin-3 (nt-3), and their trkc and trkb receptors, as well as the growth factors insulin-like growth factor i (igf-1) and basic fibroblast growth factor (bfgf), in the cerebellum and hippocampus of bdv-infected and control rats at different time points p.i. |
2001-05-17 |
2023-08-12 |
rat |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
a high level of hippocampal brain-derived neurotrophic factor (bdnf) in normally aged as compared with young rats suggests that it is important to maintain a considerable level of hippocampal bdnf during aging in order to keep normal hippocampal functions. |
2001-05-03 |
2023-08-12 |
mouse |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
kainic acid and ampa, but not nmda, caused remarkable increases in bdnf protein in the rat hippocampus and entorhinal cortex. |
2001-05-03 |
2023-08-12 |
mouse |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
picrotoxin, ptz and lindane stimulated bdnf production in the entorhinal cortex and also in the hippocampus of rats showing very severe convulsions. |
2001-05-03 |
2023-08-12 |
mouse |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
kainic acid stimulated bdnf synthesis in presynaptic hippocampal granule neurons, but not in postsynaptic neurons with its receptors, while ptz and bay-k 8644 produced the same effects in postsynaptic neurons in the entorhinal cortex (in granule neurons in the hippocampus) and in the whole cortex, respectively. |
2001-05-03 |
2023-08-12 |
mouse |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
in addition, bdnf levels in the hippocampus of mice deficient in d-myo-inositol-1,4,5-triphosphate receptor gene were scarcely different from those in the same region of controls, suggesting little involvement of intracellular calcium increase through this receptor. |
2001-05-03 |
2023-08-12 |
mouse |
| b' L Tapia-Arancibia, F Rage, L Givalois, P Dingeon, S Arancibia, F Beaug\\xc3\\xa. Effects of alcohol on brain-derived neurotrophic factor mRNA expression in discrete regions of the rat hippocampus and hypothalamus. Journal of neuroscience research. vol 63. issue 2. 2001-04-26. PMID:11169630.' |
following 12 hr of alcohol withdrawal, a significant increase in bdnf mrna expression was observed in the dentate gyrus and ca3 region of hippocampus and in the hypothalamic supraoptic nucleus. |
2001-04-26 |
2023-08-12 |
rat |
| G Biagini, M Avoli, J Marcinkiewicz, M Marcinkiewic. Brain-derived neurotrophic factor superinduction parallels anti-epileptic--neuroprotective treatment in the pilocarpine epilepsy model. Journal of neurochemistry. vol 76. issue 6. 2001-04-12. PMID:11259499. |
in addition, 2 and 24 h after pilocarpine injection, the levels of bdnf mrna were moderately increased in the unprotected group, but 'superinduced' in protected animals, especially in the neocortex and hippocampus. |
2001-04-12 |
2023-08-12 |
rat |
| N Durany, T Michel, J Kurt, F F Cruz-Sánchez, J Cervás-Navarro, P Riedere. Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 8. 2001-03-22. PMID:11156744. |
in the present study, we investigated the levels of brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) in post-mortem brain tissue of alzheimer's disease (ad) patients, and we observed a significant increase of bdnf concentration in hippocampus and parietal cortex of ad patients, as well as a negative correlation between nt-3 levels and age in hippocampus and putamen of control subjects, and for bdnf in frontal cortex. |
2001-03-22 |
2023-08-12 |
human |