| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Zhang, H S Dhillon, S Barron, R R Hicks1, R M Prasad, K B Seroog. Effects of chronic ethanol administration on expression of BDNF and trkB mRNAs in rat hippocampus after experimental brain injury. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925157. |
effects of chronic ethanol administration on expression of bdnf and trkb mrnas in rat hippocampus after experimental brain injury. |
2000-10-04 |
2023-08-12 |
rat |
| L Zhang, H S Dhillon, S Barron, R R Hicks1, R M Prasad, K B Seroog. Effects of chronic ethanol administration on expression of BDNF and trkB mRNAs in rat hippocampus after experimental brain injury. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925157. |
in the present study, we examined the effects of 6 weeks of chronic ethanol administration on lateral fluid percussion (fp) brain injury-induced alterations in expression of mrnas for the neurotrophin brain-derived neurotrophic factor (bdnf) and its high affinity receptor, trkb, in rat hippocampus. |
2000-10-04 |
2023-08-12 |
rat |
| L Zhang, H S Dhillon, S Barron, R R Hicks1, R M Prasad, K B Seroog. Effects of chronic ethanol administration on expression of BDNF and trkB mRNAs in rat hippocampus after experimental brain injury. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925157. |
in both the control- (pair-fed isocaloric sucrose) diet and the chronic ethanol-diet groups, unilateral fp brain injury induced a bilateral increase in levels of both bdnf and trkb mrnas in the dentate gyrus granule cell layer, and of bdnf mrna in hippocampal region ca3. |
2000-10-04 |
2023-08-12 |
rat |
| S A Nanda, K J Mac. Seizures and sensory stimulation result in different patterns of brain derived neurotrophic factor protein expression in the barrel cortex and hippocampus. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891580. |
in order to investigate the activity-dependent regulation of the bdnf gene, bdnf expression was examined within the rat somatosensory cortex (ssc) and hippocampus following vibrissae stimulation, kainic acid induced seizure, and pentylenetetrazol (ptz) induced seizure. |
2000-09-25 |
2023-08-12 |
rat |
| S A Nanda, K J Mac. Seizures and sensory stimulation result in different patterns of brain derived neurotrophic factor protein expression in the barrel cortex and hippocampus. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891580. |
both unilateral whisker stimulation (a model of experience dependent plasticity) and kainic acid induced seizure were able to increase the levels of bdnf protein within the ssc and hippocampus. |
2000-09-25 |
2023-08-12 |
rat |
| S A Nanda, K J Mac. Seizures and sensory stimulation result in different patterns of brain derived neurotrophic factor protein expression in the barrel cortex and hippocampus. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891580. |
finally, whisker stimulation resulted in an unexpected increase in bdnf mrna and protein levels within the hippocampus. |
2000-09-25 |
2023-08-12 |
rat |
| T Saarelainen, J A Lukkarinen, S Koponen, O H Gröhn, J Jolkkonen, E Koponen, A Haapasalo, L Alhonen, G Wong, J Koistinaho, R A Kauppinen, E Castré. Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons show increased susceptibility to cortical injury after focal cerebral ischemia. Molecular and cellular neurosciences. vol 16. issue 2. 2000-09-21. PMID:10924253. |
in order to test this hypothesis experimentally, we have produced transgenic mouse lines that overexpress the dominant-negative truncated splice variant of bdnf receptor trkb (trkb.t1) in postnatal cortical and hippocampal neurons. |
2000-09-21 |
2023-08-12 |
mouse |
| B Vollmayr, S Keck, F A Henn, P Schlos. Acute stress decreases serotonin transporter mRNA in the raphe pontis but not in other raphe nuclei of the rat. Neuroscience letters. vol 290. issue 2. 2000-09-21. PMID:10936689. |
acute stress led to a significant decrease of bdnf mrna in the hippocampus and of sert mrna in the raphe pontis, but not in other raphe nuclei investigated. |
2000-09-21 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
corticosterone effects on bdnf expression in the hippocampus. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
in this review, the question is addressed if the corticosterone effects on memory processes are mediated by alterations in the expression of the neurotrophin brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
first, studies are described investigating the effect of corticosterone on bdnf expression in the rat hippocampus. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
studies show that during water maze training, corticosterone levels rise significantly, but the bdnf expression is not suppressed in any hippocampal subfield. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
therefore, we suggest that the resistance of the hippocampal bdnf expression to suppression by corticosterone, as seen after water maze training, may contribute to an optimal memory performance. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
corticosterone effects on bdnf mrna expression in the rat hippocampus during morris water maze training. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
in the present study we have investigated the effect of corticosterone on hippocampal bdnf mrna expression after training in the morris water maze in young adult wistar rats. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
therefore, we first studied bdnf mrna levels in the hippocampus in relation to corticosterone levels at several time points after 4 training trials in the morris water maze. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
corticosterone levels were significantly increased after this procedure, and hippocampal bdnf mrna levels only displayed a minor change: an increase in ca1 at 1 hr after training. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
however, in a previous study we observed dramatically decreased hippocampal bdnf mrna levels in dentate gyrus and ca1 at 3 hr after injection of corticosterone. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
in order to analyze this discrepancy, we subsequently investigated if hippocampal bdnf mrna expression is affected by corticosterone at 3 hr after water maze training. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
adx animals which were subjected to water maze training displayed similar hippocampal bdnf mrna levels 3 hr after training compared to control adx animals. |
2000-09-14 |
2023-08-12 |
rat |