| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Russo-Neustadt, T Ha, R Ramirez, J P Kessla. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behavioural brain research. vol 120. issue 1. 2001-05-31. PMID:11173088. |
animals receiving the combined intervention showed an increase in hippocampal bdnf mrna well above baseline. |
2001-05-31 |
2023-08-12 |
rat |
| A Russo-Neustadt, T Ha, R Ramirez, J P Kessla. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behavioural brain research. vol 120. issue 1. 2001-05-31. PMID:11173088. |
enhanced swimming time correlated with increased levels of bdnf mrna in one hippocampal sub-region (ca4-hilus). |
2001-05-31 |
2023-08-12 |
rat |
| M Zocher, S Czub, J Schulte-Mönting, J C de La Torre, C Saude. Alterations in neurotrophin and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection. Journal of neurovirology. vol 6. issue 6. 2001-05-17. PMID:11175319. |
we have used rnase protection assay to measure mrna levels of the neurotrophins nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), and neurotrophin-3 (nt-3), and their trkc and trkb receptors, as well as the growth factors insulin-like growth factor i (igf-1) and basic fibroblast growth factor (bfgf), in the cerebellum and hippocampus of bdv-infected and control rats at different time points p.i. |
2001-05-17 |
2023-08-12 |
rat |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
a high level of hippocampal brain-derived neurotrophic factor (bdnf) in normally aged as compared with young rats suggests that it is important to maintain a considerable level of hippocampal bdnf during aging in order to keep normal hippocampal functions. |
2001-05-03 |
2023-08-12 |
mouse |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
kainic acid and ampa, but not nmda, caused remarkable increases in bdnf protein in the rat hippocampus and entorhinal cortex. |
2001-05-03 |
2023-08-12 |
mouse |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
picrotoxin, ptz and lindane stimulated bdnf production in the entorhinal cortex and also in the hippocampus of rats showing very severe convulsions. |
2001-05-03 |
2023-08-12 |
mouse |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
kainic acid stimulated bdnf synthesis in presynaptic hippocampal granule neurons, but not in postsynaptic neurons with its receptors, while ptz and bay-k 8644 produced the same effects in postsynaptic neurons in the entorhinal cortex (in granule neurons in the hippocampus) and in the whole cortex, respectively. |
2001-05-03 |
2023-08-12 |
mouse |
| R Katoh-Semba, I K Takeuchi, Y Inaguma, S Ichisaka, Y Hata, T Tsumoto, M Iwai, K Mikoshiba, K Kat. Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279263. |
in addition, bdnf levels in the hippocampus of mice deficient in d-myo-inositol-1,4,5-triphosphate receptor gene were scarcely different from those in the same region of controls, suggesting little involvement of intracellular calcium increase through this receptor. |
2001-05-03 |
2023-08-12 |
mouse |
| b' L Tapia-Arancibia, F Rage, L Givalois, P Dingeon, S Arancibia, F Beaug\\xc3\\xa. Effects of alcohol on brain-derived neurotrophic factor mRNA expression in discrete regions of the rat hippocampus and hypothalamus. Journal of neuroscience research. vol 63. issue 2. 2001-04-26. PMID:11169630.' |
following 12 hr of alcohol withdrawal, a significant increase in bdnf mrna expression was observed in the dentate gyrus and ca3 region of hippocampus and in the hypothalamic supraoptic nucleus. |
2001-04-26 |
2023-08-12 |
rat |
| G Biagini, M Avoli, J Marcinkiewicz, M Marcinkiewic. Brain-derived neurotrophic factor superinduction parallels anti-epileptic--neuroprotective treatment in the pilocarpine epilepsy model. Journal of neurochemistry. vol 76. issue 6. 2001-04-12. PMID:11259499. |
in addition, 2 and 24 h after pilocarpine injection, the levels of bdnf mrna were moderately increased in the unprotected group, but 'superinduced' in protected animals, especially in the neocortex and hippocampus. |
2001-04-12 |
2023-08-12 |
rat |
| N Durany, T Michel, J Kurt, F F Cruz-Sánchez, J Cervás-Navarro, P Riedere. Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 8. 2001-03-22. PMID:11156744. |
in the present study, we investigated the levels of brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) in post-mortem brain tissue of alzheimer's disease (ad) patients, and we observed a significant increase of bdnf concentration in hippocampus and parietal cortex of ad patients, as well as a negative correlation between nt-3 levels and age in hippocampus and putamen of control subjects, and for bdnf in frontal cortex. |
2001-03-22 |
2023-08-12 |
human |
| P J Kenny, S E File, M Rattra. Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus. Brain research. Molecular brain research. vol 85. issue 1-2. 2001-03-08. PMID:11146126. |
significantly decreased bdnf mrna levels in dentate gyrus, ca3 and ca1 subfields of the rat hippocampus 2 h and 24 h after administration. |
2001-03-08 |
2023-08-12 |
rat |
| P J Kenny, S E File, M Rattra. Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus. Brain research. Molecular brain research. vol 85. issue 1-2. 2001-03-08. PMID:11146126. |
these data suggests that changes in expression of hippocampal bdnf may be involved in the behavioural effects of nicotine observed after acute and chronic treatment. |
2001-03-08 |
2023-08-12 |
rat |
| E C Beattie, C L Howe, A Wilde, F M Brodsky, W C Moble. NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 19. 2001-02-22. PMID:11007890. |
in that bdnf treatment increased ap2 and clathrin at the surface membranes of hippocampal neurons, these findings may represent a physiologically significant response to nts. |
2001-02-22 |
2023-08-12 |
Not clear |
| S Marty, R Wehrlé, C Sotel. Neuronal activity and brain-derived neurotrophic factor regulate the density of inhibitory synapses in organotypic slice cultures of postnatal hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050130. |
thus, neuronal activity regulates the density of inhibitory synapses made by postnatal hippocampal interneurons, and bdnf could mediate part of this regulation. |
2001-02-22 |
2023-08-12 |
rat |
| M Fiore, J Korf, F Angelucci, L Talamini, L Alo. Prenatal exposure to methylazoxymethanol acetate in the rat alters neurotrophin levels and behavior: considerations for neurodevelopmental diseases. Physiology & behavior. vol 71. issue 1-2. 2001-02-22. PMID:11134686. |
we did a single injection of methylazoxymethanol acetate (mam) in pregnant rats on gestational day (gd) 11 or 12 to investigate the long-lasting effects of early entorhinal cortex (ec) and hippocampus maldevelopment on behavior, brain nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) levels, and the neurotrophin receptor p75 and choline acetyltransferase (chat) immunoreactivity. |
2001-02-22 |
2023-08-12 |
rat |
| M Fiore, J Korf, F Angelucci, L Talamini, L Alo. Prenatal exposure to methylazoxymethanol acetate in the rat alters neurotrophin levels and behavior: considerations for neurodevelopmental diseases. Physiology & behavior. vol 71. issue 1-2. 2001-02-22. PMID:11134686. |
in addition, rats treated on gd 12 had increased concentration of ngf and bdnf in the ec and hippocampus if compared to control rats. |
2001-02-22 |
2023-08-12 |
rat |
| Y Tang, K Yamada, Y Kanou, T Miyazaki, X Xiong, F Kambe, Y Murata, H Seo, T Nabeshim. Spatiotemporal expression of BDNF in the hippocampus induced by the continuous intracerebroventricular infusion of beta-amyloid in rats. Brain research. Molecular brain research. vol 80. issue 2. 2001-02-15. PMID:11038251. |
spatiotemporal expression of bdnf in the hippocampus induced by the continuous intracerebroventricular infusion of beta-amyloid in rats. |
2001-02-15 |
2023-08-12 |
rat |
| Y Tang, K Yamada, Y Kanou, T Miyazaki, X Xiong, F Kambe, Y Murata, H Seo, T Nabeshim. Spatiotemporal expression of BDNF in the hippocampus induced by the continuous intracerebroventricular infusion of beta-amyloid in rats. Brain research. Molecular brain research. vol 80. issue 2. 2001-02-15. PMID:11038251. |
northern blot analysis revealed a significant increase in brain-derived neurotrophic factor (bdnf) expression in the hippocampus but no change in the cerebral cortices. |
2001-02-15 |
2023-08-12 |
rat |
| Y Tang, K Yamada, Y Kanou, T Miyazaki, X Xiong, F Kambe, Y Murata, H Seo, T Nabeshim. Spatiotemporal expression of BDNF in the hippocampus induced by the continuous intracerebroventricular infusion of beta-amyloid in rats. Brain research. Molecular brain research. vol 80. issue 2. 2001-02-15. PMID:11038251. |
these results demonstrate that the continuous intracerebroventricular infusion of abeta induces selective and spatiotemporal expression of bdnf mrna in the hippocampus. |
2001-02-15 |
2023-08-12 |
rat |