| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marzena Mackowiak, Michael J O'Neill, Caroline A Hicks, David Bleakman, Phil Skolnic. An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study. Neuropharmacology. vol 43. issue 1. 2002-11-21. PMID:12213254. |
the increase in both bdnf protein and mrna expression in the dentate gyrus but not in ca1 indicates a specific role of ampa receptors in the regulation of bdnf expression in this hippocampal subfield. |
2002-11-21 |
2023-08-12 |
rat |
| Steve C Danzer, Kristy R C Crooks, Donald C Lo, James O McNamar. Increased expression of brain-derived neurotrophic factor induces formation of basal dendrites and axonal branching in dentate granule cells in hippocampal explant cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 22. 2002-11-18. PMID:12427830. |
to test this hypothesis, we transfected dgcs in rat hippocampal slice cultures with bdnf or nerve growth factor (ngf) via particle-mediated gene transfer, and we visualized the neuronal processes with cotransfected green fluorescent protein. |
2002-11-18 |
2023-08-12 |
rat |
| Jessie Truettner, Raul Busto, Weizhao Zhao, Myron D Ginsberg, Miguel A Pérez-Pinzó. Effect of ischemic preconditioning on the expression of putative neuroprotective genes in the rat brain. Brain research. Molecular brain research. vol 103. issue 1-2. 2002-11-06. PMID:12106696. |
bdnf, ngf, and c-jun were significantly upregulated in the hippocampus. |
2002-11-06 |
2023-08-12 |
rat |
| Anette Risedal, Bengt Mattsson, Per Dahlqvist, Claes Nordborg, Tommy Olsson, Barbro B Johansso. Environmental influences on functional outcome after a cortical infarct in the rat. Brain research bulletin. vol 58. issue 3. 2002-11-06. PMID:12128159. |
the bdnf gene expression in the ipsi- and contralateral cortex, thalamus, hippocampus and cerebellum did not significantly differ between the groups. |
2002-11-06 |
2023-08-12 |
rat |
| Félicien Karege, Michèle Schwald, Mbaye Ciss. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neuroscience letters. vol 328. issue 3. 2002-10-28. PMID:12147321. |
by using immunoassay and reverse transcription-polymerase chain reaction methods, bdnf protein and mrna levels were determined in serum and platelets, respectively, and in two brain structures (hippocampus and frontal cortex) of postnatal rats (one and three weeks old), young adults (two months old) and in aged animals (two years old). |
2002-10-28 |
2023-08-12 |
human |
| Félicien Karege, Michèle Schwald, Mbaye Ciss. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neuroscience letters. vol 328. issue 3. 2002-10-28. PMID:12147321. |
the results showed that brain and serum bdnf levels underwent similar changes during maturation and aging processes (analysis of variance (anova): p<0.001, p<0.001, for hippocampus and serum, respectively). |
2002-10-28 |
2023-08-12 |
human |
| Félicien Karege, Michèle Schwald, Mbaye Ciss. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neuroscience letters. vol 328. issue 3. 2002-10-28. PMID:12147321. |
during the same investigation period, the measure of bdnf mrna indicated gradual changes in the hippocampus but not in platelets (anova: p<0.001 and not significant, for hippocampus and platelets, respectively). |
2002-10-28 |
2023-08-12 |
human |
| Jaewon Lee, Wenzhen Duan, Mark P Mattso. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. Journal of neurochemistry. vol 82. issue 6. 2002-10-22. PMID:12354284. |
to determine the role of brain-derived neurotrophic factor (bdnf) in the enhancement of hippocampal neurogenesis resulting from dietary restriction (dr), heterozygous bdnf knockout (bdnf +/-) mice and wild-type mice were maintained for 3 months on dr or ad libitum (al) diets. |
2002-10-22 |
2023-08-12 |
mouse |
| Jaewon Lee, Wenzhen Duan, Mark P Mattso. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. Journal of neurochemistry. vol 82. issue 6. 2002-10-22. PMID:12354284. |
levels of bdnf protein in neurons throughout the hippocampus were decreased in bdnf +/- mice, but were increased by dr in wild-type mice and to a lesser amount in bdnf +/- mice. |
2002-10-22 |
2023-08-12 |
mouse |
| Jaewon Lee, Wenzhen Duan, Mark P Mattso. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. Journal of neurochemistry. vol 82. issue 6. 2002-10-22. PMID:12354284. |
one day after brdu injection the number of brdu-labeled cells in the dentate gyrus of the hippocampus was significantly decreased in bdnf +/- mice maintained on the al diet, suggesting that bdnf signaling is important for proliferation of neural stem cells. |
2002-10-22 |
2023-08-12 |
mouse |
| Diego Garzon, Guanhua Yu, Margaret Fahnestoc. A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex. Journal of neurochemistry. vol 82. issue 5. 2002-10-18. PMID:12358753. |
brain-derived neurotrophic factor (bdnf) supports hippocampal, cortical and basal forebrain cholinergic neurons, which lose function in alzheimer's disease. |
2002-10-18 |
2023-08-12 |
human |
| Yuji Ikegaya, Yoko Ishizaka, Norio Matsuk. BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency-response curve of synaptic plasticity. The European journal of neuroscience. vol 16. issue 1. 2002-10-09. PMID:12153539. |
bdnf attenuates hippocampal ltd via activation of phospholipase c: implications for a vertical shift in the frequency-response curve of synaptic plasticity. |
2002-10-09 |
2023-08-12 |
rat |
| Yuji Ikegaya, Yoko Ishizaka, Norio Matsuk. BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency-response curve of synaptic plasticity. The European journal of neuroscience. vol 16. issue 1. 2002-10-09. PMID:12153539. |
to understand how neurotrophins alter this synaptic modification, we have investigated the effect of brain-derived neurotrophic factor (bdnf) on long-term depression (ltd) at schaffer collateral-ca1 synapses in rat hippocampal slices. |
2002-10-09 |
2023-08-12 |
rat |
| Hideki Kawai, Wagner Zago, Darwin K Ber. Nicotinic alpha 7 receptor clusters on hippocampal GABAergic neurons: regulation by synaptic activity and neurotrophins. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 18. 2002-10-03. PMID:12223543. |
the results indicate that both nmda receptor activation and the neurotrophins bdnf and ngf are necessary to sustain the distribution patterns of alpha7-containing nicotinic receptors on gabaergic hippocampal neurons. |
2002-10-03 |
2023-08-12 |
Not clear |
| Grace Sophia Griesbach, David Allen Hovda, Raffaella Molteni, Fernando Gomez-Pinill. Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. Journal of neurotrauma. vol 19. issue 7. 2002-09-27. PMID:12184851. |
alterations in bdnf and synapsin i within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. |
2002-09-27 |
2023-08-12 |
rat |
| Grace Sophia Griesbach, David Allen Hovda, Raffaella Molteni, Fernando Gomez-Pinill. Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. Journal of neurotrauma. vol 19. issue 7. 2002-09-27. PMID:12184851. |
brain-derived neurotrophic factor (bdnf), its signal transduction receptor trkb, and its downstream effector, synapsin i, were measured in the hippocampus and occipital cortex of young animals after fluid-percussion brain injury (fpi). |
2002-09-27 |
2023-08-12 |
rat |
| Grace Sophia Griesbach, David Allen Hovda, Raffaella Molteni, Fernando Gomez-Pinill. Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. Journal of neurotrauma. vol 19. issue 7. 2002-09-27. PMID:12184851. |
these animals exhibited a contralateral increase, ranging from 40% to 75%, in bdnf mrna within both the hippocampus and occipital cortex at 24 h and 7 days after injury. |
2002-09-27 |
2023-08-12 |
rat |
| Grace Sophia Griesbach, David Allen Hovda, Raffaella Molteni, Fernando Gomez-Pinill. Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. Journal of neurotrauma. vol 19. issue 7. 2002-09-27. PMID:12184851. |
however, hippocampal bdnf protein increased in both hemispheres at postinjury day 7 and was restricted to the ipsilateral hippocampus at postinjury day 14. |
2002-09-27 |
2023-08-12 |
rat |
| Maki K Yamada, Kohsuke Nakanishi, Shizu Ohba, Takeshi Nakamura, Yuji Ikegaya, Nobuyoshi Nishiyama, Norio Matsuk. Brain-derived neurotrophic factor promotes the maturation of GABAergic mechanisms in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 17. 2002-09-13. PMID:12196581. |
to clarify how bdnf exerts its action, we evaluated the physiological, histological, and biochemical characteristics of cultured hippocampal neurons after long-term treatment with bdnf. |
2002-09-13 |
2023-08-12 |
Not clear |
| R Molteni, R J Barnard, Z Ying, C K Roberts, F Gómez-Pinill. A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088740. |
we show that animals that learn a spatial memory task faster have more brain-derived neurotrophic factor (bdnf) mrna and protein in the hippocampus. |
2002-09-03 |
2023-08-12 |
rat |