Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
R Molteni, R J Barnard, Z Ying, C K Roberts, F Gómez-Pinill. A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088740. |
two months on the hfs diet were sufficient to reduce hippocampal level of bdnf and spatial learning performance. |
2002-09-03 |
2023-08-12 |
rat |
R Molteni, R J Barnard, Z Ying, C K Roberts, F Gómez-Pinill. A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088740. |
consequent to the action of bdnf on synaptic function, downstream effectors for the action of bdnf on synaptic plasticity were reduced proportionally to bdnf levels, in the hippocampus of rats maintained on the hfs diet between 2 and 24 months. |
2002-09-03 |
2023-08-12 |
rat |
Ritsuko Katoh-Semba, Tomiko Asano, Hiroshi Ueda, Rika Morishita, Ikuo K Takeuchi, Yutaka Inaguma, Kanefusa Kat. Riluzole enhances expression of brain-derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 10. 2002-09-03. PMID:12154010. |
to elucidate the association between bdnf levels and hippocampal neurogenesis, we first conducted a search for compounds that stimulate endogenous bdnf production in hippocampal granule neurons. |
2002-09-03 |
2023-08-12 |
rat |
Ritsuko Katoh-Semba, Tomiko Asano, Hiroshi Ueda, Rika Morishita, Ikuo K Takeuchi, Yutaka Inaguma, Kanefusa Kat. Riluzole enhances expression of brain-derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 10. 2002-09-03. PMID:12154010. |
repeated, but not single, injections resulted in prolonged elevation of hippocampal bdnf and were associated with increased numbers of newly generated cells in the granule cell layer. |
2002-09-03 |
2023-08-12 |
rat |
W Duan, Z Guo, M P Mattso. Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice. Journal of neurochemistry. vol 76. issue 2. 2002-08-15. PMID:11208925. |
in the present study we show that levels of brain-derived neurotrophic factor (bdnf) are significantly increased in the hippocampus, cerebral cortex and striatum of mice maintained on an alternate day feeding dr regimen compared to animals fed ad libitum. |
2002-08-15 |
2023-08-12 |
mouse |
Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
we have reported that voluntary exercise increases bdnf mrna levels in the hippocampus; however, mechanisms underlying this regulation have not been defined. |
2002-08-12 |
2023-08-12 |
Not clear |
Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
baseline bdnf mrna was reduced in the hippocampus of sedentary animals, but exercise-induced gene upregulation was not impaired, despite complete loss of septo-hippocampal cholinergic afferents. |
2002-08-12 |
2023-08-12 |
Not clear |
Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
ox7-saporin lesion reduced baseline hippocampal bdnf mrna and attenuated exercise-induced gene upregulation, in a dose-dependent manner. |
2002-08-12 |
2023-08-12 |
Not clear |
Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
these results suggest that combined loss of septal gabaergic and cholinergic input to the hippocampus may be important for exercise-dependent bdnf gene regulation, while cholinergic activity on its own is not sufficient. |
2002-08-12 |
2023-08-12 |
Not clear |
Brian J D'Cruz, Kristofer C Fertig, Anthony J Filiano, Shawn D Hicks, Donald B DeFranco, Clifton W Callawa. Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 22. issue 7. 2002-08-09. PMID:12142569. |
this study measured levels of brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf) in hippocampal tissue of rats after resuscitation from 8 minutes of normothermic, asphyxial cardiac arrest. |
2002-08-09 |
2023-08-12 |
rat |
Brian J D'Cruz, Kristofer C Fertig, Anthony J Filiano, Shawn D Hicks, Donald B DeFranco, Clifton W Callawa. Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 22. issue 7. 2002-08-09. PMID:12142569. |
ischemia and reperfusion increased hippocampal levels of bdnf. |
2002-08-09 |
2023-08-12 |
rat |
Keiko Miyake, Wataru Yamamoto, Mina Tadokoro, Norio Takagi, Kyoko Sasakawa, Atsumi Nitta, Shoei Furukawa, Satoshi Take. Alterations in hippocampal GAP-43, BDNF, and L1 following sustained cerebral ischemia. Brain research. vol 935. issue 1-2. 2002-08-07. PMID:12062469. |
alterations in hippocampal gap-43, bdnf, and l1 following sustained cerebral ischemia. |
2002-08-07 |
2023-08-12 |
rat |
Keiko Miyake, Wataru Yamamoto, Mina Tadokoro, Norio Takagi, Kyoko Sasakawa, Atsumi Nitta, Shoei Furukawa, Satoshi Take. Alterations in hippocampal GAP-43, BDNF, and L1 following sustained cerebral ischemia. Brain research. vol 935. issue 1-2. 2002-08-07. PMID:12062469. |
the protein levels of brain-derived neurotrophic factor (bdnf), 43-kda growth-associated protein (gap-43), and adhesion protein l1 (l1) in the ipsilateral hippocampus of the me animal, determined by western blot analysis or enzyme immunoassay, were increased, unaltered, and decreased, respectively. |
2002-08-07 |
2023-08-12 |
rat |
Keiko Miyake, Wataru Yamamoto, Mina Tadokoro, Norio Takagi, Kyoko Sasakawa, Atsumi Nitta, Shoei Furukawa, Satoshi Take. Alterations in hippocampal GAP-43, BDNF, and L1 following sustained cerebral ischemia. Brain research. vol 935. issue 1-2. 2002-08-07. PMID:12062469. |
in contrast, the immunohistochemical study showed increases in a marker of axonal sprouting gap-43, and a neurotrophic factor bdnf, and a decrease in an adhesion molecule l1 in some areas of the hippocampal ischemic penumbra of such animals. |
2002-08-07 |
2023-08-12 |
rat |
Ann M Rasmusson, Libin Shi, Ronald Duma. Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 2. 2002-08-07. PMID:12093587. |
downregulation of bdnf mrna in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. |
2002-08-07 |
2023-08-12 |
rat |
Ann M Rasmusson, Libin Shi, Ronald Duma. Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 2. 2002-08-07. PMID:12093587. |
this study examined the effects of footshock stress and re-exposure to cues previously associated with footshock on expression of brain-derived neurotrophic factor (bdnf) mrna in the hippocampus of male rats. |
2002-08-07 |
2023-08-12 |
rat |
Ann M Rasmusson, Libin Shi, Ronald Duma. Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 2. 2002-08-07. PMID:12093587. |
the data suggest that psychological, as well as unconditioned physical stress, can decrease hippocampal bdnf mrna. |
2002-08-07 |
2023-08-12 |
rat |
Annette Gärtner, Volker Staige. Neurotrophin secretion from hippocampal neurons evoked by long-term-potentiation-inducing electrical stimulation patterns. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 9. 2002-06-11. PMID:11983920. |
using electrical field stimulation of primary cultures of hippocampal neurons, we demonstrate that short high-frequency bursts of stimuli that induce ltp evoke also an instantaneous secretion of bdnf. |
2002-06-11 |
2023-08-12 |
Not clear |
Haiyun Xu, Hong Qing, Wenfu Lu, David Keegan, J Steven Richardson, Jennifer Chlan-Fourney, Xin Min L. Quetiapine attenuates the immobilization stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus. Neuroscience letters. vol 321. issue 1-2. 2002-05-23. PMID:11872258. |
this study examined the influence of quetiapine on the decrease of brain-derived neurotrophic factor (bdnf) expression, induced by chronic immobilization stress, in the hippocampus of the rat. |
2002-05-23 |
2023-08-12 |
rat |
Helen E Scharfman, Jeffrey H Goodman, Anne L Sollas, Susan D Crol. Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor. Experimental neurology. vol 174. issue 2. 2002-05-02. PMID:11922662. |
the results of several studies have contributed to the hypothesis that bdnf promotes seizure activity, particularly in adult hippocampus. |
2002-05-02 |
2023-08-12 |
rat |