| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Tartaglia, J Du, W J Tyler, E Neale, L Pozzo-Miller, B L. Protein synthesis-dependent and -independent regulation of hippocampal synapses by brain-derived neurotrophic factor. The Journal of biological chemistry. vol 276. issue 40. 2001-12-04. PMID:11483592. |
long-term treatment of hippocampal slice cultures with bdnf increased the number of docked vesicles, but not that of reserve pool vesicles, at ca1 excitatory synapses. |
2001-12-04 |
2023-08-12 |
Not clear |
| J H Sun, X Q Yan, H Xiao, J W Zhou, Y Z Chen, C A Wan. Restoration of decreased N-methyl-d-asparate receptor activity by brain-derived neurotrophic factor in the cultured hippocampal neurons: involvement of cAMP. Archives of biochemistry and biophysics. vol 394. issue 2. 2001-12-04. PMID:11594735. |
to elucidate the underlying mechanisms, whole-cell patch-clamp recording was used to assess the effect of bdnf on the responses of cultured hippocampal neurons to the glutamate receptor agonist nmda. |
2001-12-04 |
2023-08-12 |
Not clear |
| J H Sun, X Q Yan, H Xiao, J W Zhou, Y Z Chen, C A Wan. Restoration of decreased N-methyl-d-asparate receptor activity by brain-derived neurotrophic factor in the cultured hippocampal neurons: involvement of cAMP. Archives of biochemistry and biophysics. vol 394. issue 2. 2001-12-04. PMID:11594735. |
elevating the amount of cytosolic camp by preincubation with forskolin or sp-camp also enhanced nmda currents as effectively as bdnf in 18-day-old hippocampal neurons. |
2001-12-04 |
2023-08-12 |
Not clear |
| J H Sun, X Q Yan, H Xiao, J W Zhou, Y Z Chen, C A Wan. Restoration of decreased N-methyl-d-asparate receptor activity by brain-derived neurotrophic factor in the cultured hippocampal neurons: involvement of cAMP. Archives of biochemistry and biophysics. vol 394. issue 2. 2001-12-04. PMID:11594735. |
measurement of the cellular content of camp by ria indicated that cultured hippocampal neurons showed decreased basal camp levels at the time nmda currents were decreased and bdnf increased the decreased camp levels. |
2001-12-04 |
2023-08-12 |
Not clear |
| J H Sun, X Q Yan, H Xiao, J W Zhou, Y Z Chen, C A Wan. Restoration of decreased N-methyl-d-asparate receptor activity by brain-derived neurotrophic factor in the cultured hippocampal neurons: involvement of cAMP. Archives of biochemistry and biophysics. vol 394. issue 2. 2001-12-04. PMID:11594735. |
taken together, these results suggest that bdnf may restore decreased nmda receptor activity in cultured hippocampal neurons by the camp pathway. |
2001-12-04 |
2023-08-12 |
Not clear |
| S L Patterson, C Pittenger, A Morozov, K C Martin, H Scanlin, C Drake, E R Kande. Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase. Neuron. vol 32. issue 1. 2001-12-04. PMID:11604144. |
we find that increases in camp can rapidly activate the bdnf receptor trkb and induce bdnf-dependent long-lasting potentiation at the schaffer collateral-ca1 synapse in hippocampus. |
2001-12-04 |
2023-08-12 |
Not clear |
| B Chen, D Dowlatshahi, G M MacQueen, J F Wang, L T Youn. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biological psychiatry. vol 50. issue 4. 2001-11-01. PMID:11522260. |
increased hippocampal bdnf immunoreactivity in subjects treated with antidepressant medication. |
2001-11-01 |
2023-08-12 |
human |
| B Chen, D Dowlatshahi, G M MacQueen, J F Wang, L T Youn. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biological psychiatry. vol 50. issue 4. 2001-11-01. PMID:11522260. |
this study was designed to test whether the diagnosis of a mood disorder, or treatment with an antidepressant or mood stabilizer was associated with changes in hippocampal bdnf in postmortem brain. |
2001-11-01 |
2023-08-12 |
human |
| V Butterweck, H Winterhoff, M Herkenha. St John's wort, hypericin, and imipramine: a comparative analysis of mRNA levels in brain areas involved in HPA axis control following short-term and long-term administration in normal and stressed rats. Molecular psychiatry. vol 6. issue 5. 2001-10-18. PMID:11526469. |
it decreased mrna levels of 5-ht(1a) and brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2001-10-18 |
2023-08-12 |
rat |
| M Fiore, L Aloe, C Westenbroek, T Amendola, A Antonelli, J Kor. Bromodeoxyuridine and methylazoxymethanol exposure during brain development affects behavior in rats: consideration for a role of nerve growth factor and brain derived neurotrophic factor. Neuroscience letters. vol 309. issue 2. 2001-10-11. PMID:11502358. |
brdu induced decreased ngf and bdnf levels in the hippocampus. |
2001-10-11 |
2023-08-12 |
rat |
| J Paul, K Gottmann, V Lessman. NT-3 regulates BDNF-induced modulation of synaptic transmission in cultured hippocampal neurons. Neuroreport. vol 12. issue 12. 2001-10-04. PMID:11522939. |
although the expression of nt-3 and bdnf in the rodent hippocampus coincides during perinatal development, little is known about possible functional interactions between both neurotrophins in synaptic development. |
2001-10-04 |
2023-08-12 |
Not clear |
| J Paul, K Gottmann, V Lessman. NT-3 regulates BDNF-induced modulation of synaptic transmission in cultured hippocampal neurons. Neuroreport. vol 12. issue 12. 2001-10-04. PMID:11522939. |
here, we have investigated the effects of combined long-term application of nt-3 and bdnf on excitatory glutamatergic (mepsc) and inhibitory gabaergic miniature synaptic currents (mipsc) in cultured embryonic hippocampal neurons. |
2001-10-04 |
2023-08-12 |
Not clear |
| J Paul, K Gottmann, V Lessman. NT-3 regulates BDNF-induced modulation of synaptic transmission in cultured hippocampal neurons. Neuroreport. vol 12. issue 12. 2001-10-04. PMID:11522939. |
in summary, these data suggest an nt-3 controlled modulation of bdnf signalling in differentiating hippocampal neurons. |
2001-10-04 |
2023-08-12 |
Not clear |
| B K Lipska, Z Z Khaing, C S Weickert, D R Weinberge. BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. The European journal of neuroscience. vol 14. issue 1. 2001-09-27. PMID:11488957. |
bdnf mrna expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. |
2001-09-27 |
2023-08-12 |
rat |
| B K Lipska, Z Z Khaing, C S Weickert, D R Weinberge. BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. The European journal of neuroscience. vol 14. issue 1. 2001-09-27. PMID:11488957. |
to clarify the effects of antipsychotic drugs used in the therapy of schizophrenia on bdnf mrna, we studied its expression in rats treated with clozapine and haloperidol and in rats with neonatal lesions of the ventral hippocampus, used as an animal model of schizophrenia. |
2001-09-27 |
2023-08-12 |
rat |
| B K Lipska, Z Z Khaing, C S Weickert, D R Weinberge. BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. The European journal of neuroscience. vol 14. issue 1. 2001-09-27. PMID:11488957. |
both antipsychotic drugs reduced bdnf expression in the hippocampus of control rats, but did not significantly lower its expression in the prefrontal cortex. |
2001-09-27 |
2023-08-12 |
rat |
| B K Lipska, Z Z Khaing, C S Weickert, D R Weinberge. BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. The European journal of neuroscience. vol 14. issue 1. 2001-09-27. PMID:11488957. |
the neonatal hippocampal lesion itself suppressed bdnf mrna expression in the dentate gyrus and tended to reduce its expression in the prefrontal cortex. |
2001-09-27 |
2023-08-12 |
rat |
| F Gómez-Pinilla, V So, J P Kessla. Spatial learning induces neurotrophin receptor and synapsin I in the hippocampus. Brain research. vol 904. issue 1. 2001-09-27. PMID:11516407. |
we report that rats learning a spatial memory task in the morris water maze show elevated expression of the signal transduction receptor for bdnf and the synaptic associated protein synapsin i in the hippocampus. |
2001-09-27 |
2023-08-12 |
rat |
| F Gómez-Pinilla, V So, J P Kessla. Spatial learning induces neurotrophin receptor and synapsin I in the hippocampus. Brain research. vol 904. issue 1. 2001-09-27. PMID:11516407. |
levels of trkb mrna in the hippocampus were attenuated after learning acquisition (day 20), but synapsin i mrna was still elevated, suggesting that the bdnf system may participate in events secondary to learning, such as strengthening of neural circuits. |
2001-09-27 |
2023-08-12 |
rat |
| T Ivanova, C Beye. Pre- and postnatal expression of brain-derived neurotrophic factor mRNA/protein and tyrosine protein kinase receptor B mRNA in the mouse hippocampus. Neuroscience letters. vol 307. issue 1. 2001-09-27. PMID:11516565. |
brain-derived neurotrophic factor (bdnf) is implicated in the control of hippocampal development. |
2001-09-27 |
2023-08-12 |
mouse |