| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haiyun Xu, J Steven Richardson, Xin-Min L. Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 1. 2003-03-17. PMID:12496940. |
to further test this hypothesis, brain-derived neurotrophic factor (bdnf), b cell lymphoma protein-2 (bcl-2), and copper-zinc superoxide dismutase (cu/zn-sod) were examined immunohistochemically in hippocampal neurons of sprague-dawley rats following daily treatment with 5 or 10 mg/kg of amitriptyline or venlafaxine for 21 days. |
2003-03-17 |
2023-08-12 |
rat |
| Haiyun Xu, J Steven Richardson, Xin-Min L. Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 1. 2003-03-17. PMID:12496940. |
at 5 mg/kg, both amitriptyline and venlafaxine increased the intensity of bdnf immunostaining in hippocampal pyramidal neurons, and the intensity of bcl-2 immunostaining in hippocampal mossy fibers, but did not alter the cu/zn-sod immunoreactivity. |
2003-03-17 |
2023-08-12 |
rat |
| Haiyun Xu, J Steven Richardson, Xin-Min L. Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 1. 2003-03-17. PMID:12496940. |
the high dose of venlafaxine, however, decreased the intensity of bdnf immunostaining in all subareas of the hippocampus and increased the intensity of cu/zn-sod immunostaining in the dentate granular cell layer. |
2003-03-17 |
2023-08-12 |
rat |
| Ou Bai, Jennifer Chlan-Fourney, Rudy Bowen, David Keegan, Xin-Min L. Expression of brain-derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs. Journal of neuroscience research. vol 71. issue 1. 2003-03-12. PMID:12478621. |
we examined the effects of chronic (28 days) administration of typical and atypical antipsychotic drugs on bdnf mrna expression in the rat hippocampus using in situ hybridization. |
2003-03-12 |
2023-08-12 |
rat |
| Ou Bai, Jennifer Chlan-Fourney, Rudy Bowen, David Keegan, Xin-Min L. Expression of brain-derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs. Journal of neuroscience research. vol 71. issue 1. 2003-03-12. PMID:12478621. |
in contrast, the atypical antipsychotic agents clozapine (10 mg/kg) and olanzapine (2.7 mg/kg) up-regulated bdnf mrna expression in ca1, ca3, and dentate gyrus regions of the rat hippocampus compared with their respective controls (p < 0.01). |
2003-03-12 |
2023-08-12 |
rat |
| Ou Bai, Jennifer Chlan-Fourney, Rudy Bowen, David Keegan, Xin-Min L. Expression of brain-derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs. Journal of neuroscience research. vol 71. issue 1. 2003-03-12. PMID:12478621. |
these findings demonstrate that the typical and atypical antipsychotic drugs differentially regulate bdnf mrna expression in rat hippocampus. |
2003-03-12 |
2023-08-12 |
rat |
| P Baldelli, M Novara, V Carabelli, J M Hernández-Guijo, E Carbon. BDNF up-regulates evoked GABAergic transmission in developing hippocampus by potentiating presynaptic N- and P/Q-type Ca2+ channels signalling. The European journal of neuroscience. vol 16. issue 12. 2003-03-12. PMID:12492424. |
bdnf up-regulates evoked gabaergic transmission in developing hippocampus by potentiating presynaptic n- and p/q-type ca2+ channels signalling. |
2003-03-12 |
2023-08-12 |
rat |
| P Baldelli, M Novara, V Carabelli, J M Hernández-Guijo, E Carbon. BDNF up-regulates evoked GABAergic transmission in developing hippocampus by potentiating presynaptic N- and P/Q-type Ca2+ channels signalling. The European journal of neuroscience. vol 16. issue 12. 2003-03-12. PMID:12492424. |
chronic application of brain-derived neurotrophic factor (bdnf) induces new selective synthesis of non-l-type ca2+ channels (n, p/q, r) at the soma of cultured hippocampal neurons. |
2003-03-12 |
2023-08-12 |
rat |
| P Baldelli, M Novara, V Carabelli, J M Hernández-Guijo, E Carbon. BDNF up-regulates evoked GABAergic transmission in developing hippocampus by potentiating presynaptic N- and P/Q-type Ca2+ channels signalling. The European journal of neuroscience. vol 16. issue 12. 2003-03-12. PMID:12492424. |
to address this issue we studied the long-term effects of bdnf on miniature and stimulus-evoked gabaergic transmission in rat embryo hippocampal neurons. |
2003-03-12 |
2023-08-12 |
rat |
| P Baldelli, M Novara, V Carabelli, J M Hernández-Guijo, E Carbon. BDNF up-regulates evoked GABAergic transmission in developing hippocampus by potentiating presynaptic N- and P/Q-type Ca2+ channels signalling. The European journal of neuroscience. vol 16. issue 12. 2003-03-12. PMID:12492424. |
this selective action resembles the previously observed up-regulatory effects of bdnf on somatic ca2+ currents in developing hippocampus, suggesting that potentiation of presynaptic n- and p/q-channel signalling belongs to a manifold mechanism by which bdnf increases the efficiency of stimulus-evoked gabaergic transmission. |
2003-03-12 |
2023-08-12 |
rat |
| Mariana Alonso, Monica R M Vianna, Amaicha M Depino, Tadeu Mello e Souza, Patricia Pereira, German Szapiro, Haydee Viola, Fernando Pitossi, Ivan Izquierdo, Jorge H Medin. BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus. vol 12. issue 4. 2003-03-05. PMID:12201640. |
because brain-derived neutrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in the adult hippocampus, we examined the role of bdnf in stm and ltm formation of a hippocampal-dependent one-trial fear-motivated learning task in rats. |
2003-03-05 |
2023-08-12 |
human |
| Mariana Alonso, Monica R M Vianna, Amaicha M Depino, Tadeu Mello e Souza, Patricia Pereira, German Szapiro, Haydee Viola, Fernando Pitossi, Ivan Izquierdo, Jorge H Medin. BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus. vol 12. issue 4. 2003-03-05. PMID:12201640. |
using a competitive rt-pcr quantitation method, we found that inhibitory avoidance training is associated with a rapid and transient increase in bdnf mrna expression in the hippocampus. |
2003-03-05 |
2023-08-12 |
human |
| John D E Gabrieli, Alison R Presto. Visualizing genetic influences on human brain functions. Cell. vol 112. issue 2. 2003-02-14. PMID:12553902. |
, in this issue of cell, integrate genetics and functional brain imaging by showing that variation in the human brain-derived neurotrophic factor (bdnf) gene is associated with variation in episodic memory ability and in hippocampal neurochemistry and function. |
2003-02-14 |
2023-08-12 |
human |
| Michael F Egan, Masami Kojima, Joseph H Callicott, Terry E Goldberg, Bhaskar S Kolachana, Alessandro Bertolino, Eugene Zaitsev, Bert Gold, David Goldman, Michael Dean, Bai Lu, Daniel R Weinberge. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. vol 112. issue 2. 2003-02-14. PMID:12553913. |
the bdnf val66met polymorphism affects activity-dependent secretion of bdnf and human memory and hippocampal function. |
2003-02-14 |
2023-08-12 |
human |
| Michael F Egan, Masami Kojima, Joseph H Callicott, Terry E Goldberg, Bhaskar S Kolachana, Alessandro Bertolino, Eugene Zaitsev, Bert Gold, David Goldman, Michael Dean, Bai Lu, Daniel R Weinberge. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. vol 112. issue 2. 2003-02-14. PMID:12553913. |
brain-derived neurotrophic factor (bdnf) modulates hippocampal plasticity and hippocampal-dependent memory in cell models and in animals. |
2003-02-14 |
2023-08-12 |
human |
| Michael F Egan, Masami Kojima, Joseph H Callicott, Terry E Goldberg, Bhaskar S Kolachana, Alessandro Bertolino, Eugene Zaitsev, Bert Gold, David Goldman, Michael Dean, Bai Lu, Daniel R Weinberge. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. vol 112. issue 2. 2003-02-14. PMID:12553913. |
these results demonstrate a role for bdnf and its val/met polymorphism in human memory and hippocampal function and suggest val/met exerts these effects by impacting intracellular trafficking and activity-dependent secretion of bdnf. |
2003-02-14 |
2023-08-12 |
human |
| M Roceri, W Hendriks, G Racagni, B A Ellenbroek, M A Riv. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Molecular psychiatry. vol 7. issue 6. 2003-02-11. PMID:12140784. |
early maternal deprivation reduces the expression of bdnf and nmda receptor subunits in rat hippocampus. |
2003-02-11 |
2023-08-12 |
rat |
| M Roceri, W Hendriks, G Racagni, B A Ellenbroek, M A Riv. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Molecular psychiatry. vol 7. issue 6. 2003-02-11. PMID:12140784. |
we found that in adulthood the expression of bdnf as well as of nr-2a and nr-2b, two nmda receptor forming subunits, were significantly reduced in the hippocampus of md rats whereas, among other structures, a slight reduction of nr-2a and 2b was detected only in prefrontal cortex. |
2003-02-11 |
2023-08-12 |
rat |
| M Roceri, W Hendriks, G Racagni, B A Ellenbroek, M A Riv. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Molecular psychiatry. vol 7. issue 6. 2003-02-11. PMID:12140784. |
furthermore we found that in md rats the modulation of hippocampal bdnf in response to an acute stress was altered, indicating a persistent functional impairment in its regulation, which may subserve a specific role for coping with challenging situations. |
2003-02-11 |
2023-08-12 |
rat |
| Sandra Dieni, Sandra Ree. Distribution of brain-derived neurotrophic factor and TrkB receptor proteins in the fetal and postnatal hippocampus and cerebellum of the guinea pig. The Journal of comparative neurology. vol 454. issue 3. 2003-02-07. PMID:12442314. |
this study investigates the distribution of brain-derived neurotrophic factor protein (bdnf) and its receptor, trkb, during the development of hippocampus and cerebellum in a long-gestation species, the guinea pig. |
2003-02-07 |
2023-08-12 |
Not clear |