| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jaewon Lee, Wenzhen Duan, Mark P Mattso. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. Journal of neurochemistry. vol 82. issue 6. 2002-10-22. PMID:12354284. |
one day after brdu injection the number of brdu-labeled cells in the dentate gyrus of the hippocampus was significantly decreased in bdnf +/- mice maintained on the al diet, suggesting that bdnf signaling is important for proliferation of neural stem cells. |
2002-10-22 |
2023-08-12 |
mouse |
| Diego Garzon, Guanhua Yu, Margaret Fahnestoc. A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex. Journal of neurochemistry. vol 82. issue 5. 2002-10-18. PMID:12358753. |
brain-derived neurotrophic factor (bdnf) supports hippocampal, cortical and basal forebrain cholinergic neurons, which lose function in alzheimer's disease. |
2002-10-18 |
2023-08-12 |
human |
| Yuji Ikegaya, Yoko Ishizaka, Norio Matsuk. BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency-response curve of synaptic plasticity. The European journal of neuroscience. vol 16. issue 1. 2002-10-09. PMID:12153539. |
bdnf attenuates hippocampal ltd via activation of phospholipase c: implications for a vertical shift in the frequency-response curve of synaptic plasticity. |
2002-10-09 |
2023-08-12 |
rat |
| Yuji Ikegaya, Yoko Ishizaka, Norio Matsuk. BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency-response curve of synaptic plasticity. The European journal of neuroscience. vol 16. issue 1. 2002-10-09. PMID:12153539. |
to understand how neurotrophins alter this synaptic modification, we have investigated the effect of brain-derived neurotrophic factor (bdnf) on long-term depression (ltd) at schaffer collateral-ca1 synapses in rat hippocampal slices. |
2002-10-09 |
2023-08-12 |
rat |
| Hideki Kawai, Wagner Zago, Darwin K Ber. Nicotinic alpha 7 receptor clusters on hippocampal GABAergic neurons: regulation by synaptic activity and neurotrophins. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 18. 2002-10-03. PMID:12223543. |
the results indicate that both nmda receptor activation and the neurotrophins bdnf and ngf are necessary to sustain the distribution patterns of alpha7-containing nicotinic receptors on gabaergic hippocampal neurons. |
2002-10-03 |
2023-08-12 |
Not clear |
| Grace Sophia Griesbach, David Allen Hovda, Raffaella Molteni, Fernando Gomez-Pinill. Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. Journal of neurotrauma. vol 19. issue 7. 2002-09-27. PMID:12184851. |
alterations in bdnf and synapsin i within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. |
2002-09-27 |
2023-08-12 |
rat |
| Grace Sophia Griesbach, David Allen Hovda, Raffaella Molteni, Fernando Gomez-Pinill. Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. Journal of neurotrauma. vol 19. issue 7. 2002-09-27. PMID:12184851. |
brain-derived neurotrophic factor (bdnf), its signal transduction receptor trkb, and its downstream effector, synapsin i, were measured in the hippocampus and occipital cortex of young animals after fluid-percussion brain injury (fpi). |
2002-09-27 |
2023-08-12 |
rat |
| Grace Sophia Griesbach, David Allen Hovda, Raffaella Molteni, Fernando Gomez-Pinill. Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. Journal of neurotrauma. vol 19. issue 7. 2002-09-27. PMID:12184851. |
these animals exhibited a contralateral increase, ranging from 40% to 75%, in bdnf mrna within both the hippocampus and occipital cortex at 24 h and 7 days after injury. |
2002-09-27 |
2023-08-12 |
rat |
| Grace Sophia Griesbach, David Allen Hovda, Raffaella Molteni, Fernando Gomez-Pinill. Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced neuroplasticity. Journal of neurotrauma. vol 19. issue 7. 2002-09-27. PMID:12184851. |
however, hippocampal bdnf protein increased in both hemispheres at postinjury day 7 and was restricted to the ipsilateral hippocampus at postinjury day 14. |
2002-09-27 |
2023-08-12 |
rat |
| Maki K Yamada, Kohsuke Nakanishi, Shizu Ohba, Takeshi Nakamura, Yuji Ikegaya, Nobuyoshi Nishiyama, Norio Matsuk. Brain-derived neurotrophic factor promotes the maturation of GABAergic mechanisms in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 17. 2002-09-13. PMID:12196581. |
to clarify how bdnf exerts its action, we evaluated the physiological, histological, and biochemical characteristics of cultured hippocampal neurons after long-term treatment with bdnf. |
2002-09-13 |
2023-08-12 |
Not clear |
| R Molteni, R J Barnard, Z Ying, C K Roberts, F Gómez-Pinill. A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088740. |
we show that animals that learn a spatial memory task faster have more brain-derived neurotrophic factor (bdnf) mrna and protein in the hippocampus. |
2002-09-03 |
2023-08-12 |
rat |
| R Molteni, R J Barnard, Z Ying, C K Roberts, F Gómez-Pinill. A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088740. |
two months on the hfs diet were sufficient to reduce hippocampal level of bdnf and spatial learning performance. |
2002-09-03 |
2023-08-12 |
rat |
| R Molteni, R J Barnard, Z Ying, C K Roberts, F Gómez-Pinill. A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088740. |
consequent to the action of bdnf on synaptic function, downstream effectors for the action of bdnf on synaptic plasticity were reduced proportionally to bdnf levels, in the hippocampus of rats maintained on the hfs diet between 2 and 24 months. |
2002-09-03 |
2023-08-12 |
rat |
| Ritsuko Katoh-Semba, Tomiko Asano, Hiroshi Ueda, Rika Morishita, Ikuo K Takeuchi, Yutaka Inaguma, Kanefusa Kat. Riluzole enhances expression of brain-derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 10. 2002-09-03. PMID:12154010. |
to elucidate the association between bdnf levels and hippocampal neurogenesis, we first conducted a search for compounds that stimulate endogenous bdnf production in hippocampal granule neurons. |
2002-09-03 |
2023-08-12 |
rat |
| Ritsuko Katoh-Semba, Tomiko Asano, Hiroshi Ueda, Rika Morishita, Ikuo K Takeuchi, Yutaka Inaguma, Kanefusa Kat. Riluzole enhances expression of brain-derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 10. 2002-09-03. PMID:12154010. |
repeated, but not single, injections resulted in prolonged elevation of hippocampal bdnf and were associated with increased numbers of newly generated cells in the granule cell layer. |
2002-09-03 |
2023-08-12 |
rat |
| W Duan, Z Guo, M P Mattso. Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice. Journal of neurochemistry. vol 76. issue 2. 2002-08-15. PMID:11208925. |
in the present study we show that levels of brain-derived neurotrophic factor (bdnf) are significantly increased in the hippocampus, cerebral cortex and striatum of mice maintained on an alternate day feeding dr regimen compared to animals fed ad libitum. |
2002-08-15 |
2023-08-12 |
mouse |
| Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
we have reported that voluntary exercise increases bdnf mrna levels in the hippocampus; however, mechanisms underlying this regulation have not been defined. |
2002-08-12 |
2023-08-12 |
Not clear |
| Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
baseline bdnf mrna was reduced in the hippocampus of sedentary animals, but exercise-induced gene upregulation was not impaired, despite complete loss of septo-hippocampal cholinergic afferents. |
2002-08-12 |
2023-08-12 |
Not clear |
| Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
ox7-saporin lesion reduced baseline hippocampal bdnf mrna and attenuated exercise-induced gene upregulation, in a dose-dependent manner. |
2002-08-12 |
2023-08-12 |
Not clear |
| Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
these results suggest that combined loss of septal gabaergic and cholinergic input to the hippocampus may be important for exercise-dependent bdnf gene regulation, while cholinergic activity on its own is not sufficient. |
2002-08-12 |
2023-08-12 |
Not clear |