| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Baldelli, M Novara, V Carabelli, J M Hernández-Guijo, E Carbon. BDNF up-regulates evoked GABAergic transmission in developing hippocampus by potentiating presynaptic N- and P/Q-type Ca2+ channels signalling. The European journal of neuroscience. vol 16. issue 12. 2003-03-12. PMID:12492424. |
this selective action resembles the previously observed up-regulatory effects of bdnf on somatic ca2+ currents in developing hippocampus, suggesting that potentiation of presynaptic n- and p/q-channel signalling belongs to a manifold mechanism by which bdnf increases the efficiency of stimulus-evoked gabaergic transmission. |
2003-03-12 |
2023-08-12 |
rat |
| Mariana Alonso, Monica R M Vianna, Amaicha M Depino, Tadeu Mello e Souza, Patricia Pereira, German Szapiro, Haydee Viola, Fernando Pitossi, Ivan Izquierdo, Jorge H Medin. BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus. vol 12. issue 4. 2003-03-05. PMID:12201640. |
because brain-derived neutrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in the adult hippocampus, we examined the role of bdnf in stm and ltm formation of a hippocampal-dependent one-trial fear-motivated learning task in rats. |
2003-03-05 |
2023-08-12 |
human |
| Mariana Alonso, Monica R M Vianna, Amaicha M Depino, Tadeu Mello e Souza, Patricia Pereira, German Szapiro, Haydee Viola, Fernando Pitossi, Ivan Izquierdo, Jorge H Medin. BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus. vol 12. issue 4. 2003-03-05. PMID:12201640. |
using a competitive rt-pcr quantitation method, we found that inhibitory avoidance training is associated with a rapid and transient increase in bdnf mrna expression in the hippocampus. |
2003-03-05 |
2023-08-12 |
human |
| John D E Gabrieli, Alison R Presto. Visualizing genetic influences on human brain functions. Cell. vol 112. issue 2. 2003-02-14. PMID:12553902. |
, in this issue of cell, integrate genetics and functional brain imaging by showing that variation in the human brain-derived neurotrophic factor (bdnf) gene is associated with variation in episodic memory ability and in hippocampal neurochemistry and function. |
2003-02-14 |
2023-08-12 |
human |
| Michael F Egan, Masami Kojima, Joseph H Callicott, Terry E Goldberg, Bhaskar S Kolachana, Alessandro Bertolino, Eugene Zaitsev, Bert Gold, David Goldman, Michael Dean, Bai Lu, Daniel R Weinberge. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. vol 112. issue 2. 2003-02-14. PMID:12553913. |
the bdnf val66met polymorphism affects activity-dependent secretion of bdnf and human memory and hippocampal function. |
2003-02-14 |
2023-08-12 |
human |
| Michael F Egan, Masami Kojima, Joseph H Callicott, Terry E Goldberg, Bhaskar S Kolachana, Alessandro Bertolino, Eugene Zaitsev, Bert Gold, David Goldman, Michael Dean, Bai Lu, Daniel R Weinberge. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. vol 112. issue 2. 2003-02-14. PMID:12553913. |
brain-derived neurotrophic factor (bdnf) modulates hippocampal plasticity and hippocampal-dependent memory in cell models and in animals. |
2003-02-14 |
2023-08-12 |
human |
| Michael F Egan, Masami Kojima, Joseph H Callicott, Terry E Goldberg, Bhaskar S Kolachana, Alessandro Bertolino, Eugene Zaitsev, Bert Gold, David Goldman, Michael Dean, Bai Lu, Daniel R Weinberge. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. vol 112. issue 2. 2003-02-14. PMID:12553913. |
these results demonstrate a role for bdnf and its val/met polymorphism in human memory and hippocampal function and suggest val/met exerts these effects by impacting intracellular trafficking and activity-dependent secretion of bdnf. |
2003-02-14 |
2023-08-12 |
human |
| M Roceri, W Hendriks, G Racagni, B A Ellenbroek, M A Riv. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Molecular psychiatry. vol 7. issue 6. 2003-02-11. PMID:12140784. |
early maternal deprivation reduces the expression of bdnf and nmda receptor subunits in rat hippocampus. |
2003-02-11 |
2023-08-12 |
rat |
| M Roceri, W Hendriks, G Racagni, B A Ellenbroek, M A Riv. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Molecular psychiatry. vol 7. issue 6. 2003-02-11. PMID:12140784. |
we found that in adulthood the expression of bdnf as well as of nr-2a and nr-2b, two nmda receptor forming subunits, were significantly reduced in the hippocampus of md rats whereas, among other structures, a slight reduction of nr-2a and 2b was detected only in prefrontal cortex. |
2003-02-11 |
2023-08-12 |
rat |
| M Roceri, W Hendriks, G Racagni, B A Ellenbroek, M A Riv. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Molecular psychiatry. vol 7. issue 6. 2003-02-11. PMID:12140784. |
furthermore we found that in md rats the modulation of hippocampal bdnf in response to an acute stress was altered, indicating a persistent functional impairment in its regulation, which may subserve a specific role for coping with challenging situations. |
2003-02-11 |
2023-08-12 |
rat |
| Sandra Dieni, Sandra Ree. Distribution of brain-derived neurotrophic factor and TrkB receptor proteins in the fetal and postnatal hippocampus and cerebellum of the guinea pig. The Journal of comparative neurology. vol 454. issue 3. 2003-02-07. PMID:12442314. |
this study investigates the distribution of brain-derived neurotrophic factor protein (bdnf) and its receptor, trkb, during the development of hippocampus and cerebellum in a long-gestation species, the guinea pig. |
2003-02-07 |
2023-08-12 |
Not clear |
| Annakaisa Haapasalo, Ilkka Sipola, Kim Larsson, Karl E O Akerman, Peter Stoilov, Stefan Stamm, Garry Wong, Eero Castre. Regulation of TRKB surface expression by brain-derived neurotrophic factor and truncated TRKB isoforms. The Journal of biological chemistry. vol 277. issue 45. 2003-02-06. PMID:12202482. |
we report here that bdnf regulates the cell surface levels of transfected or endogenously expressed full-length trkb, depending on the exposure time in neuroblastoma cells and primary hippocampal neurons. |
2003-02-06 |
2023-08-12 |
Not clear |
| Jonathan C Gewirtz, Andrew C Chen, Rose Terwilliger, Ronald C Duman, Gerard J Mare. Modulation of DOI-induced increases in cortical BDNF expression by group II mGlu receptors. Pharmacology, biochemistry, and behavior. vol 73. issue 2. 2003-02-05. PMID:12117585. |
previous studies have shown that 5-hydroxytryptamine(2a) (5-ht(2a)) receptor activation induces changes in the pattern of brain-derived neurotrophic factor (bdnf) mrna expression in the neocortex and hippocampus, and that 5-ht(2a) receptor blockade interferes with the induction of bdnf mrna by stress. |
2003-02-05 |
2023-08-12 |
Not clear |
| Paula C Ashe, Jennifer Chlan-Fourney, Augusto V Juorio, Xin-Min L. Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus. Brain research. vol 956. issue 1. 2003-01-29. PMID:12426055. |
brain-derived neurotrophic factor (bdnf) mrna in rats with neonatal ibotenic acid lesions of the ventral hippocampus. |
2003-01-29 |
2023-08-12 |
rat |
| Paula C Ashe, Jennifer Chlan-Fourney, Augusto V Juorio, Xin-Min L. Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus. Brain research. vol 956. issue 1. 2003-01-29. PMID:12426055. |
bdnf mrna was examined by in situ hybridization in the prefrontal cortex and hippocampus of animals with neonatal ibotenic acid lesions of the ventral hippocampus, a putative neurodevelopmental animal model of schizophrenia. |
2003-01-29 |
2023-08-12 |
rat |
| Paula C Ashe, Jennifer Chlan-Fourney, Augusto V Juorio, Xin-Min L. Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus. Brain research. vol 956. issue 1. 2003-01-29. PMID:12426055. |
results demonstrate that animals with neonatal ibotenic acid lesions of the ventral hippocampus have reduced basal levels of bdnf mrna. |
2003-01-29 |
2023-08-12 |
rat |
| Jennifer Chlan-Fourney, Paula Ashe, Kirk Nylen, Augusto V Juorio, Xin Min L. Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration. Brain research. vol 954. issue 1. 2003-01-24. PMID:12393228. |
differential regulation of hippocampal bdnf mrna by typical and atypical antipsychotic administration. |
2003-01-24 |
2023-08-12 |
rat |
| Jennifer Chlan-Fourney, Paula Ashe, Kirk Nylen, Augusto V Juorio, Xin Min L. Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration. Brain research. vol 954. issue 1. 2003-01-24. PMID:12393228. |
chronic (19 day) but not acute (45 min) antipsychotic administration significantly altered levels of hippocampal bdnf mrna. |
2003-01-24 |
2023-08-12 |
rat |
| Jennifer Chlan-Fourney, Paula Ashe, Kirk Nylen, Augusto V Juorio, Xin Min L. Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration. Brain research. vol 954. issue 1. 2003-01-24. PMID:12393228. |
in addition, whereas chronic treatment with the strong d2 receptor-blocker haloperidol significantly downregulated hippocampal bdnf mrna, the selective 5-ht2 receptor-blocker ritanserin significantly upregulated ca1 hippocampal bdnf mrna in comparison to controls. |
2003-01-24 |
2023-08-12 |
rat |
| Jennifer Chlan-Fourney, Paula Ashe, Kirk Nylen, Augusto V Juorio, Xin Min L. Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration. Brain research. vol 954. issue 1. 2003-01-24. PMID:12393228. |
since high doses of risperidone and clozapine produce potent inhibition of both 5-ht2 and d2 receptors, while lower doses produce significantly greater 5-ht2 vs. d2 receptor blockade, a dose-response study was employed to determine whether low doses of these atypical antipsychotics would also upregulate hippocampal bdnf mrna in the absence of significant d2 receptor blockade. |
2003-01-24 |
2023-08-12 |
rat |