| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Wu, R Molteni, Z Ying, F Gomez-Pinill. A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor. Neuroscience. vol 119. issue 2. 2003-07-30. PMID:12770552. |
learning performance decreased according to levels of brain-derived neurotrophic factor (bdnf) in individual rats, such that rats with the worst learning efficacy showed the lowest levels of bdnf in the hippocampus. |
2003-07-30 |
2023-08-12 |
rat |
| Makoto Mizuno, Kiyofumi Yamada, Jue He, Akira Nakajima, Toshitaka Nabeshim. Involvement of BDNF receptor TrkB in spatial memory formation. Learning & memory (Cold Spring Harbor, N.Y.). vol 10. issue 2. 2003-07-25. PMID:12663749. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin, which also enhances hippocampal synaptic transmission and efficacy by increasing nmda receptor activity. |
2003-07-25 |
2023-08-12 |
rat |
| J G Hensler, E E Ladenheim, W E Lyon. Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (+/-) mice. Journal of neurochemistry. vol 85. issue 5. 2003-07-24. PMID:12753073. |
in the hippocampus, 5-ht1a receptor-stimulated [35s]gtp gamma s binding was significantly attenuated in bdnf (+/-) mice. |
2003-07-24 |
2023-08-12 |
mouse |
| Yong Sun, Jian Shi, Pei-Hua L. [Neurotrophic factors and neural stem cells]. Sheng li ke xue jin zhan [Progress in physiology]. vol 33. issue 4. 2003-07-17. PMID:12650066. |
ngf, bdnf, nt-3, nt-4/5 and nt-6 constitute ngf family (the neurotrophins), which may enhance both survival and differentiation of neurons from the egf-responsive hippocampal and the subventricular zone neural stem cells. |
2003-07-17 |
2023-08-12 |
Not clear |
| Seung-Hee Lee, Jin-Hee Han, Jung-Hwan Choi, Eun-Young Huh, Yunhee Kim Kwon, Bong-Kiun Kaan. The effect of brain-derived neurotrophic factor on neuritogenesis and synaptic plasticity in Aplysia neurons and the hippocampal cell line HiB5. Molecules and cells. vol 15. issue 2. 2003-07-17. PMID:12803487. |
we examined the specific effect of bdnf on neurite outgrowth and synaptic plasticity in cultured aplysia neurons and a multipotent rat hippocampal stem cell line (hib5). |
2003-07-17 |
2023-08-12 |
rat |
| Bernadeta Michalski, Margaret Fahnestoc. Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease. Brain research. Molecular brain research. vol 111. issue 1-2. 2003-07-16. PMID:12654514. |
brain-derived neurotrophic factor (bdnf) promotes the function and survival of the major neuronal types affected in alzheimer disease, such as hippocampal, cortical and basal forebrain cholinergic neurons. |
2003-07-16 |
2023-08-12 |
human |
| Bernadeta Michalski, Margaret Fahnestoc. Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease. Brain research. Molecular brain research. vol 111. issue 1-2. 2003-07-16. PMID:12654514. |
we and others have demonstrated a reduction in bdnf mrna expression in alzheimer's disease hippocampus and cortex, which may help to explain the selective vulnerability of these neurons. |
2003-07-16 |
2023-08-12 |
human |
| Eleni Dicou, Claire-Marie Rangon, Fabien Guimiot, Michael Spedding, Pierre Gressen. Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain. Brain research. vol 970. issue 1-2. 2003-07-08. PMID:12706264. |
administration of cx614 to neonatal mice was followed by upregulation of hippocampal and cortical bdnf expression. |
2003-07-08 |
2023-08-12 |
mouse |
| P R Blanquet, J Mariani, P Dere. A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus. Neuroscience. vol 118. issue 2. 2003-06-16. PMID:12699783. |
brain-derived neurotrophic factor (bdnf) plays fundamental roles in synaptic plasticity in rat hippocampus. |
2003-06-16 |
2023-08-12 |
rat |
| P R Blanquet, J Mariani, P Dere. A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus. Neuroscience. vol 118. issue 2. 2003-06-16. PMID:12699783. |
recently, using rat hippocampal slices, we found that bdnf induces activation of calcium/calmodulin-dependent protein kinase 2 (camkii), a critical mediator of synaptic plasticity. |
2003-06-16 |
2023-08-12 |
rat |
| Hiroyoshi Sei, Hiroaki Fujihara, Yoichi Ueta, Kyoji Morita, Kunio Kitahama, Yusuke Morit. Single eight-hour shift of light-dark cycle increases brain-derived neurotrophic factor protein levels in the rat hippocampus. Life sciences. vol 73. issue 1. 2003-05-29. PMID:12726886. |
we have therefore observed the responses of bdnf protein in the hippocampus, cerebellum and brainstem under conditions of ld change. |
2003-05-29 |
2023-08-12 |
rat |
| Hiroyoshi Sei, Hiroaki Fujihara, Yoichi Ueta, Kyoji Morita, Kunio Kitahama, Yusuke Morit. Single eight-hour shift of light-dark cycle increases brain-derived neurotrophic factor protein levels in the rat hippocampus. Life sciences. vol 73. issue 1. 2003-05-29. PMID:12726886. |
under an 8-h ld phase advance, the levels of hippocampal bdnf were significantly increased on the day of the phase change, while the levels in the cerebellum and brainstem remained constant. |
2003-05-29 |
2023-08-12 |
rat |
| Hiroyoshi Sei, Hiroaki Fujihara, Yoichi Ueta, Kyoji Morita, Kunio Kitahama, Yusuke Morit. Single eight-hour shift of light-dark cycle increases brain-derived neurotrophic factor protein levels in the rat hippocampus. Life sciences. vol 73. issue 1. 2003-05-29. PMID:12726886. |
thus, a single ld shift acutely affects hippocampal bdnf metabolism with no large stress response. |
2003-05-29 |
2023-08-12 |
rat |
| b' Francesco Angelucci, Luigi Aloe, Patricia Jim\\xc3\\xa9nez-Vasquez, Aleksander A Math\\xc3\\xa. Electroconvulsive stimuli alter nerve growth factor but not brain-derived neurotrophic factor concentrations in brains of a rat model of depression. Neuropeptides. vol 37. issue 1. 2003-05-15. PMID:12637036.' |
in contrast, ecs did not change bdnf concentration in hippocampus, frontal cortex and striatum of fsl and frl rats. |
2003-05-15 |
2023-08-12 |
rat |
| Arjan Scheepens, Guido Wassink, Carlos E Blanc. The effect of a global birth asphyxia on the ontogeny of BDNF and NGF protein expression in the juvenile brain. Brain research. Developmental brain research. vol 140. issue 2. 2003-05-14. PMID:12586427. |
we used a model of global birth asphyxia in the rat to follow the ontogeny of bdnf and ngf protein levels within the normal and asphyctic hippocampus and cerebellum for the first 28 days of postnatal life. |
2003-05-14 |
2023-08-12 |
rat |
| Arjan Scheepens, Guido Wassink, Carlos E Blanc. The effect of a global birth asphyxia on the ontogeny of BDNF and NGF protein expression in the juvenile brain. Brain research. Developmental brain research. vol 140. issue 2. 2003-05-14. PMID:12586427. |
asphyxia also caused a delayed increase in bdnf content within the hippocampus but decreased bdnf levels within the cerebellum. |
2003-05-14 |
2023-08-12 |
rat |
| René Garci. Stress, metaplasticity, and antidepressants. Current molecular medicine. vol 2. issue 7. 2003-05-09. PMID:12420802. |
at the molecular level, it has been suggested that these cellular deficiencies, mostly detected in the hippocampus, result from a decrease in the expression of brain-derived neurotrophic factor (bdnf) associated with elevation of glucocorticoids. |
2003-05-09 |
2023-08-12 |
Not clear |
| René Garci. Stress, metaplasticity, and antidepressants. Current molecular medicine. vol 2. issue 7. 2003-05-09. PMID:12420802. |
however, as also revealed by converging lines of evidence, high levels of glucocorticoids down-regulate hippocampal synaptic connectivity ('negative' metaplasticity), whereas an increase in expression of bdnf up-regulates connectivity in the hippocampus ('positive' metaplasticity). |
2003-05-09 |
2023-08-12 |
Not clear |
| Heather A Bimonte-Nelson, Christopher L Hunter, Matthew E Nelson, Ann-Charlotte E Granhol. Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome. Behavioural brain research. vol 139. issue 1-2. 2003-05-02. PMID:12642175. |
we evaluated memory as well as brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf) protein levels in basal forebrain, frontal cortex, hippocampus, and striatum in ts65dn mice at the age when cholinergic degeneration is first observed, and compared values to normosomic controls. |
2003-05-02 |
2023-08-12 |
mouse |
| Fernando Aguado, Maria A Carmona, Esther Pozas, Agustín Aguiló, Francisco J Martínez-Guijarro, Soledad Alcantara, Victor Borrell, Rafael Yuste, Carlos F Ibañez, Eduardo Sorian. BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2. Development (Cambridge, England). vol 130. issue 7. 2003-04-24. PMID:12588844. |
by using transgenic embryos that overexpress bdnf under the control of the nestin promoter, we show here that bdnf controls the emergence and robustness of spontaneous activity in embryonic hippocampal slices. |
2003-04-24 |
2023-08-12 |
Not clear |