| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Helen E Scharfman, Thomas C Mercurio, Jeffrey H Goodman, Marlene A Wilson, Neil J MacLusk. Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 37. 2004-01-16. PMID:14684866. |
these studies suggest that hippocampal bdnf levels change across the estrous cycle, accompanied by neurophysiological responses that resemble the effects of bdnf treatment. |
2004-01-16 |
2023-08-12 |
rat |
| Helen E Scharfman, Thomas C Mercurio, Jeffrey H Goodman, Marlene A Wilson, Neil J MacLusk. Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 37. 2004-01-16. PMID:14684866. |
periovulatory changes in hippocampal function may, thus, involve estrogen-induced increases in bdnf expression. |
2004-01-16 |
2023-08-12 |
rat |
| A S Ivy, F G Rodriguez, C Garcia, M J Chen, A A Russo-Neustad. Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant. Pharmacology, biochemistry, and behavior. vol 75. issue 1. 2004-01-07. PMID:12759116. |
antidepressants and physical exercise have been shown to increase the transcription of hippocampal brain-derived neurotrophic factor (bdnf). |
2004-01-07 |
2023-08-12 |
Not clear |
| Chiaki Itami, Fumitaka Kimura, Tomoko Kohno, Masato Matsuoka, Masumi Ichikawa, Tadaharu Tsumoto, Shun Nakamur. Brain-derived neurotrophic factor-dependent unmasking of "silent" synapses in the developing mouse barrel cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 22. 2004-01-05. PMID:14557544. |
brain-derived neurotrophic factor (bdnf) is a critical modulator of central synaptic functions such as long-term potentiation in the hippocampal and visual cortex. |
2004-01-05 |
2023-08-12 |
mouse |
| J A Gorski, S A Balogh, J M Wehner, K R Jone. Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice. Neuroscience. vol 121. issue 2. 2003-12-19. PMID:14521993. |
early-onset forebrain-restricted bdnf mutant mice (emx-bdnf(ko)) that develop in the absence of bdnf in the dorsal cortex, hippocampus, and parts of the ventral cortex and amygdala failed to learn the morris water maze task, a hippocampal-dependent visuo-spatial learning task. |
2003-12-19 |
2023-08-12 |
mouse |
| Janet Alder, Smita Thakker-Varia, Debra A Bangasser, May Kuroiwa, Mark R Plummer, Tracey J Shors, Ira B Blac. Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 34. 2003-12-16. PMID:14645472. |
vgf protein was also upregulated by bdnf treatment and was expressed in a punctate manner in dissociated hippocampal neurons. |
2003-12-16 |
2023-08-12 |
Not clear |
| R A Johnson, J S Rhodes, S L Jeffrey, T Garland, G S Mitchel. Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946694. |
voluntary wheel running in rats increases hippocampal brain-derived neurotrophic factor (bdnf) expression, a neurochemical important for neuronal survival, differentiation, connectivity and synaptic plasticity. |
2003-12-05 |
2023-08-12 |
mouse |
| R A Johnson, J S Rhodes, S L Jeffrey, T Garland, G S Mitchel. Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946694. |
baseline hippocampal bdnf levels (mice housed without running wheels) were similar in s and c mice. |
2003-12-05 |
2023-08-12 |
mouse |
| R A Johnson, J S Rhodes, S L Jeffrey, T Garland, G S Mitchel. Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946694. |
following seven nights of running, hippocampal bdnf increased significantly more in s versus c mice, and levels were correlated with distance run (considering c and s mice together). |
2003-12-05 |
2023-08-12 |
mouse |
| R A Johnson, J S Rhodes, S L Jeffrey, T Garland, G S Mitchel. Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946694. |
spinal and cerebellar bdnf and hippocampal nt-3 levels were not significantly affected by wheel running in any group, but there was a small, positive correlation between spinal c3-c6 bdnf levels and distance run (considering c and s mice together). |
2003-12-05 |
2023-08-12 |
mouse |
| R A Johnson, J S Rhodes, S L Jeffrey, T Garland, G S Mitchel. Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946694. |
this is the first study to demonstrate that mice which choose to run more have greater elevations in hippocampal bdnf, suggesting enhanced potential for exercise-induced hippocampal neuroplasticity. |
2003-12-05 |
2023-08-12 |
mouse |
| Rebecca A Johnson, Gordon S Mitchel. Exercise-induced changes in hippocampal brain-derived neurotrophic factor and neurotrophin-3: effects of rat strain. Brain research. vol 983. issue 1-2. 2003-11-28. PMID:12914971. |
we tested the hypothesis that exercise-induced changes in hippocampal brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) differ among rat strains exhibiting a range of voluntary wheel running activity. |
2003-11-28 |
2023-08-12 |
rat |
| Rebecca A Johnson, Gordon S Mitchel. Exercise-induced changes in hippocampal brain-derived neurotrophic factor and neurotrophin-3: effects of rat strain. Brain research. vol 983. issue 1-2. 2003-11-28. PMID:12914971. |
hippocampal bdnf concentrations in sedentary rats were higher in pvg versus sprague-dawley rats. |
2003-11-28 |
2023-08-12 |
rat |
| Ashok K Shetty, Vandana Zaman, Geetha A Shett. Hippocampal neurotrophin levels in a kainate model of temporal lobe epilepsy: a lack of correlation between brain-derived neurotrophic factor content and progression of aberrant dentate mossy fiber sprouting. Journal of neurochemistry. vol 87. issue 1. 2003-11-12. PMID:12969262. |
a significant upregulation of neurotrophins particularly brain-derived neurotrophic factor (bdnf) is believed to be involved in the initiation of epileptogenic changes such as the aberrant axonal sprouting and synaptic reorganization in the injured hippocampus. |
2003-11-12 |
2023-08-12 |
Not clear |
| Ashok K Shetty, Vandana Zaman, Geetha A Shett. Hippocampal neurotrophin levels in a kainate model of temporal lobe epilepsy: a lack of correlation between brain-derived neurotrophic factor content and progression of aberrant dentate mossy fiber sprouting. Journal of neurochemistry. vol 87. issue 1. 2003-11-12. PMID:12969262. |
we measured chronic changes in the levels of bdnf, nerve growth factor (ngf) and neurotrophin-3 (nt-3) in the adult hippocampus using enzyme-linked immunosorbent assay (elisa) after a unilateral intracerebroventricular administration of kainic acid (ka), a model of temporal lobe epilepsy. |
2003-11-12 |
2023-08-12 |
Not clear |
| Ashok K Shetty, Vandana Zaman, Geetha A Shett. Hippocampal neurotrophin levels in a kainate model of temporal lobe epilepsy: a lack of correlation between brain-derived neurotrophic factor content and progression of aberrant dentate mossy fiber sprouting. Journal of neurochemistry. vol 87. issue 1. 2003-11-12. PMID:12969262. |
in the ka-lesioned hippocampus, the neurotrophins bdnf and ngf were upregulated at 4 days post-lesion, in comparison to their levels in the intact hippocampus. |
2003-11-12 |
2023-08-12 |
Not clear |
| Bai L. Pro-region of neurotrophins: role in synaptic modulation. Neuron. vol 39. issue 5. 2003-11-10. PMID:12948441. |
a single nucleotide mutation in the pro-region appears to affect synaptic targeting and activity-dependent secretion of bdnf in hippocampal neurons. |
2003-11-10 |
2023-08-12 |
Not clear |
| R Hellweg, C A F von Arnim, M Büchner, R Huber, M W Riep. Neuroprotection and neuronal dysfunction upon repetitive inhibition of oxidative phosphorylation. Experimental neurology. vol 183. issue 2. 2003-10-31. PMID:14552876. |
we conclude that the time interval between mild, subclinical repetitive inhibition of oxidative phosphorylation determines hippocampal neuronal impairment and integrity and modulates ngf and bdnf differently. |
2003-10-31 |
2023-08-12 |
Not clear |
| E Head, I T Lott, P R Hof, C Bouras, J H Su, R Kim, R Haier, C W Cotma. Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome. Journal of neuropathology and experimental neurology. vol 62. issue 9. 2003-10-28. PMID:14533781. |
immunohistochemistry and confocal microscopy studies in the hippocampus from 15 individuals ranging in age from 5 months to 67 years compared markers of normal and abnormal tau accumulation (phosphorylated tau [at8, mc-1], tau-1, n-terminal tau) with the extent and location of neuronal growth marker immunoreactivity (bdnf, gap-43, map-2). |
2003-10-28 |
2023-08-12 |
Not clear |
| Julie C Lauterborn, Giang S Truong, Michel Baudry, Xiaoning Bi, Gary Lynch, Christine M Gal. Chronic elevation of brain-derived neurotrophic factor by ampakines. The Journal of pharmacology and experimental therapeutics. vol 307. issue 1. 2003-10-23. PMID:12893840. |
in rat hippocampal slice cultures, cx614 rapidly increases bdnf gene expression but with time, mrna levels fall despite the continued presence of active drug. |
2003-10-23 |
2023-08-12 |
rat |