| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R M Barrientos, D B Sprunger, S Campeau, E A Higgins, L R Watkins, J W Rudy, S F Maie. Brain-derived neurotrophic factor mRNA downregulation produced by social isolation is blocked by intrahippocampal interleukin-1 receptor antagonist. Neuroscience. vol 121. issue 4. 2004-03-01. PMID:14580934. |
these data suggest that hippocampal-dependent memory impairments induced by elevated levels of brain il-1beta may occur via an il-1beta-induced downregulation in hippocampal bdnf. |
2004-03-01 |
2023-08-12 |
Not clear |
| T R Mhyre, C D Applegat. Persistent regional increases in brain-derived neurotrophic factor in the flurothyl model of epileptogenesis are dependent upon the kindling status of the animal. Neuroscience. vol 121. issue 4. 2004-03-01. PMID:14580953. |
regional expression patterns of bdnf in the hippocampus, hypothalamus, and frontal cortex were also elevated by one dpsz and returned to control values by 14 dpsz in mice that received four hfe seizures. |
2004-03-01 |
2023-08-12 |
mouse |
| T R Mhyre, C D Applegat. Persistent regional increases in brain-derived neurotrophic factor in the flurothyl model of epileptogenesis are dependent upon the kindling status of the animal. Neuroscience. vol 121. issue 4. 2004-03-01. PMID:14580953. |
in contrast, fully kindled mice had significantly elevated bdnf levels within the hippocampus, hypothalamus, neocortex, and striatum that remained elevated through at least 14 dpsz, while levels were unchanged in the cerebellum and piriform cortex. |
2004-03-01 |
2023-08-12 |
mouse |
| S Vaynman, Z Ying, F Gomez-Pinill. Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity. Neuroscience. vol 122. issue 3. 2004-02-17. PMID:14622908. |
we found that although bdnf mediates exercise-induced hippocampal plasticity, additional molecules, i.e. |
2004-02-17 |
2023-08-12 |
Not clear |
| Anna Josephson, Alexandra Trifunovski, Camilla Schéele, Johan Widenfalk, Claes Wahlestedt, Stefan Brené, Lars Olson, Christian Spenge. Activity-induced and developmental downregulation of the Nogo receptor. Cell and tissue research. vol 311. issue 3. 2004-02-11. PMID:12658441. |
strikingly, kainic acid led to a strong transient downregulation of ngr mrna levels in gyrus dentatus, hippocampus, and neocortex during a time when bdnf mrna was upregulated instead. |
2004-02-11 |
2023-08-12 |
rat |
| Claudia Dolci, Angela Montaruli, Eliana Roveda, Isabella Barajon, Laura Vizzotto, Gigliola Grassi Zucconi, Franca Carandent. Circadian variations in expression of the trkB receptor in adult rat hippocampus. Brain research. vol 994. issue 1. 2004-02-10. PMID:14642449. |
the expression of bdnf (mrna and protein) and trkb mrna shows circadian oscillations in rat hippocampal homogenates. |
2004-02-10 |
2023-08-12 |
rat |
| Hiroaki Fujihara, Hiroyoshi Sei, Yusuke Morita, Yoichi Ueta, Kyoji Morit. Short-term sleep disturbance enhances brain-derived neurotrophic factor gene expression in rat hippocampus by acting as internal stressor. Journal of molecular neuroscience : MN. vol 21. issue 3. 2004-01-29. PMID:14645989. |
sleep disturbance induced the elevation of both bdnf protein and its mrna levels in the hippocampus but not in the cerebellum or the brainstem, and the elevated bdnf mrna expression in the hippocampus returned toward basal levels during the sleep recovery period when the rebound of sleep duration was observed. |
2004-01-29 |
2023-08-12 |
rat |
| Hiroaki Fujihara, Hiroyoshi Sei, Yusuke Morita, Yoichi Ueta, Kyoji Morit. Short-term sleep disturbance enhances brain-derived neurotrophic factor gene expression in rat hippocampus by acting as internal stressor. Journal of molecular neuroscience : MN. vol 21. issue 3. 2004-01-29. PMID:14645989. |
these findings suggest the possibility that short-term disturbance of the sleep/wake cycle and, hence, the partial reduction of non-rem sleep duration, might exert a potential influence on neuronal and/or glial cells as an internal stressor, resulting in the elevation of bdnf gene expression in rat hippocampus. |
2004-01-29 |
2023-08-12 |
rat |
| Cortney A Turner, Mark H Lewi. Environmental enrichment: effects on stereotyped behavior and neurotrophin levels. Physiology & behavior. vol 80. issue 2-3. 2004-01-26. PMID:14637224. |
the motor cortex, striatum, and hippocampus were dissected, and the levels of brain-derived neurotrophin factor (bdnf) and nerve growth factor (ngf) in each brain region were analyzed using promega elisa kits. |
2004-01-26 |
2023-08-12 |
mouse |
| Cortney A Turner, Mark H Lewi. Environmental enrichment: effects on stereotyped behavior and neurotrophin levels. Physiology & behavior. vol 80. issue 2-3. 2004-01-26. PMID:14637224. |
there were no differences in either ngf or bdnf in either the motor cortex or the hippocampus. |
2004-01-26 |
2023-08-12 |
mouse |
| Panaree Parnpiansil, Nuanchan Jutapakdeegul, Thyon Chentanez, Naiphinich Kotchabhakd. Exercise during pregnancy increases hippocampal brain-derived neurotrophic factor mRNA expression and spatial learning in neonatal rat pup. Neuroscience letters. vol 352. issue 1. 2004-01-20. PMID:14615046. |
physical activities for a few days can increase brain-derived neurotrophic factor (bdnf) mrna in rat hippocampus. |
2004-01-20 |
2023-08-12 |
rat |
| Panaree Parnpiansil, Nuanchan Jutapakdeegul, Thyon Chentanez, Naiphinich Kotchabhakd. Exercise during pregnancy increases hippocampal brain-derived neurotrophic factor mRNA expression and spatial learning in neonatal rat pup. Neuroscience letters. vol 352. issue 1. 2004-01-20. PMID:14615046. |
to investigate the influence of maternal exercise during pregnancy on rat pup hippocampal bdnf mrna, we studied its expression by a semi-quantitative rt-pcr method after young pregnant rats were exercised on a motor driven treadmill. |
2004-01-20 |
2023-08-12 |
rat |
| Panaree Parnpiansil, Nuanchan Jutapakdeegul, Thyon Chentanez, Naiphinich Kotchabhakd. Exercise during pregnancy increases hippocampal brain-derived neurotrophic factor mRNA expression and spatial learning in neonatal rat pup. Neuroscience letters. vol 352. issue 1. 2004-01-20. PMID:14615046. |
pups of exercised mothers had significantly increased hippocampal bdnf mrna expression compared to the control rat pups at birth (on postnatal day 0) (p<0.001). |
2004-01-20 |
2023-08-12 |
rat |
| Panaree Parnpiansil, Nuanchan Jutapakdeegul, Thyon Chentanez, Naiphinich Kotchabhakd. Exercise during pregnancy increases hippocampal brain-derived neurotrophic factor mRNA expression and spatial learning in neonatal rat pup. Neuroscience letters. vol 352. issue 1. 2004-01-20. PMID:14615046. |
in contrast, hippocampal bdnf mrna expression in pups of exercised mothers decreased significantly on postnatal day 28 (p<0.002). |
2004-01-20 |
2023-08-12 |
rat |
| Panaree Parnpiansil, Nuanchan Jutapakdeegul, Thyon Chentanez, Naiphinich Kotchabhakd. Exercise during pregnancy increases hippocampal brain-derived neurotrophic factor mRNA expression and spatial learning in neonatal rat pup. Neuroscience letters. vol 352. issue 1. 2004-01-20. PMID:14615046. |
thus, physical exercise during gestation in pregnant mothers can increase hippocampal bdnf mrna expression of postnatal pups and result in an improvement in spatial learning in pups from exercised dams. |
2004-01-20 |
2023-08-12 |
rat |
| Tomás R Guilarte, Christopher D Toscano, Jennifer L McGlothan, Shelley A Weave. Environmental enrichment reverses cognitive and molecular deficits induced by developmental lead exposure. Annals of neurology. vol 53. issue 1. 2004-01-16. PMID:12509847. |
enhanced learning performance of pb2+-exposed animals reared in an enriched environment was associated with recovery of deficits in n-methyl-d-aspartate receptor subunit 1 (nr1) mrna and induction of brain-derived neurotrophic factor (bdnf) mrna in the hippocampus. |
2004-01-16 |
2023-08-12 |
rat |
| J Patrick Kesslak, Kenneth R Chuang, Nicole C Berchtol. Spatial learning is delayed and brain-derived neurotrophic factor mRNA expression inhibited by administration of MK-801 in rats. Neuroscience letters. vol 353. issue 2. 2004-01-16. PMID:14664909. |
in situ hybridization for hippocampal bdnf mrna indicated significant increases in the yoked and learning groups. |
2004-01-16 |
2023-08-12 |
rat |
| Helen E Scharfman, Thomas C Mercurio, Jeffrey H Goodman, Marlene A Wilson, Neil J MacLusk. Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 37. 2004-01-16. PMID:14684866. |
to test the hypothesis that induction of bdnf may contribute to changes in hippocampal excitability occurring during the female reproductive cycle, we examined the distribution of bdnf immunoreactivity and changes in ca1 and ca3 electrophysiology across the estrous cycle in rats. |
2004-01-16 |
2023-08-12 |
rat |
| Helen E Scharfman, Thomas C Mercurio, Jeffrey H Goodman, Marlene A Wilson, Neil J MacLusk. Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 37. 2004-01-16. PMID:14684866. |
hippocampal bdnf immunoreactivity increased on the day of proestrus as well as on the following morning (estrus), relative to metestrus or ovariectomized animals. |
2004-01-16 |
2023-08-12 |
rat |
| Helen E Scharfman, Thomas C Mercurio, Jeffrey H Goodman, Marlene A Wilson, Neil J MacLusk. Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 37. 2004-01-16. PMID:14684866. |
hyperexcitability in area ca3 at proestrus was blocked by exposure to the high-affinity neurotrophin receptor antagonist k252a, or an antagonist of the alpha7 nicotinic cholinergic receptor, whereas it was induced at metestrus by the addition of bdnf to hippocampal slices. |
2004-01-16 |
2023-08-12 |
rat |