| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Nishi, M Kawata, E C Azmiti. Trophic interactions between brain-derived neurotrophic factor and s100beta on cultured serotonergic neurons. Brain research. vol 868. issue 1. 2000-08-04. PMID:10841894. |
bdnf (50 ng/ml) treatment for 3 h enhanced s100beta immunoreactivity in both raphe and hippocampal glial cells. |
2000-08-04 |
2023-08-12 |
rat |
| J Hall, K L Thomas, B J Everit. Rapid and selective induction of BDNF expression in the hippocampus during contextual learning. Nature neuroscience. vol 3. issue 6. 2000-07-13. PMID:10816306. |
rapid and selective induction of bdnf expression in the hippocampus during contextual learning. |
2000-07-13 |
2023-08-12 |
Not clear |
| H F Farhadi, S J Mowla, K Petrecca, S J Morris, N G Seidah, R A Murph. Neurotrophin-3 sorts to the constitutive secretory pathway of hippocampal neurons and is diverted to the regulated secretory pathway by coexpression with brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 11. 2000-06-15. PMID:10818141. |
in contrast, hippocampal neurons use the regulated secretory pathway to process brain-derived neurotrophic factor (bdnf), which alters synaptic activity when released acutely from dense-core vesicles. |
2000-06-15 |
2023-08-12 |
Not clear |
| M Righi, E Tongiorgi, A Cattane. Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 9. 2000-06-02. PMID:10777780. |
brain-derived neurotrophic factor (bdnf) induces dendritic targeting of bdnf and tyrosine kinase b mrnas in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway. |
2000-06-02 |
2023-08-12 |
Not clear |
| M Righi, E Tongiorgi, A Cattane. Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 9. 2000-06-02. PMID:10777780. |
we show that brief depolarizations are sufficient to induce accumulation of bdnf and trkb mrnas in dendrites of hippocampal neurons. |
2000-06-02 |
2023-08-12 |
Not clear |
| M Righi, E Tongiorgi, A Cattane. Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 9. 2000-06-02. PMID:10777780. |
because most hippocampal neurons coexpress bdnf and trkb receptors, these results show that the subcellular distribution of bdnf-trkb mrnas is under the control of an autocrine-paracrine bdnf-trkb-dependent loop. |
2000-06-02 |
2023-08-12 |
Not clear |
| M M Bolton, A J Pittman, D C L. Brain-derived neurotrophic factor differentially regulates excitatory and inhibitory synaptic transmission in hippocampal cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 9. 2000-06-02. PMID:10777787. |
in this context, we have found that bdnf dramatically increases the frequency of spontaneously initiated action potentials in hippocampal neurons in dissociated culture. |
2000-06-02 |
2023-08-12 |
Not clear |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
brain-derived neurotrophic factor (bdnf) plays an important role in hippocampal neuroplasticity. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
in particular, bdnf upregulation in the hippocampus by epileptic seizures suggests its involvement in the neuronal rearrangements accompanying epileptogenesis. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
we have shown previously that chronic infusion of bdnf in the hippocampus induces a long-term delay in hippocampal kindling progression. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
although bdnf has been shown to enhance the excitability of this structure upon acute application, long-term transcriptional regulations leading to increased inhibition within the hippocampus may account for its suppressive effects on epileptogenesis. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
therefore, the long-term consequences of a 7-day chronic intrahippocampal infusion of bdnf (12 microg/day) were investigated up to 2 weeks after the end of the infusion, on the expression of neurotransmitters contained in inhibitory hippocampal interneurons and which display anti-epileptic properties. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
conversely, bdnf induces a long-lasting increase of neuropeptide y (npy) in the hippocampus, measured by immunohistochemistry and radioimmunoassay, outlasting the end of the infusion by at least 7 days. |
2000-05-25 |
2023-08-12 |
rat |
| S Reibel, B Vivien-Roels, B T Lê, Y Larmet, J Carnahan, C Marescaux, A Depauli. Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712639. |
the enduring increase of neuropeptide y expression induced by bdnf in the hippocampus suggests that this neurotrophin can trigger long-term genomic effects, which may contribute to the neuroplasticity of this structure, in particular during epileptogenesis. |
2000-05-25 |
2023-08-12 |
rat |
| F Asztely, M Kokaia, K Olofsdotter, U Ortegren, O Lindval. Afferent-specific modulation of short-term synaptic plasticity by neurotrophins in dentate gyrus. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712646. |
using field recordings and whole-cell patch-clamp recordings in hippocampal slices, we found that paired-pulse (pp) depression at mpp-granule cell synapses was impaired in bdnf knock-out (+/-) mice, but pp facilitation at lpp synapses to the same cells was not impaired. |
2000-05-25 |
2023-08-12 |
mouse |
| K Heese, U Otten, P Mathivet, M Raiteri, C Marescaux, R Bernascon. GABA(B) receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats. Neuropharmacology. vol 39. issue 3. 2000-05-16. PMID:10698011. |
in this study we show that single, physiologically-active and non-convulsive doses of the three gaba(b) receptor antagonists cgp 36742, cgp 56433a and cgp 56999a increase ngf and bdnf mrna levels by 200-400% and protein levels by 200-250% in rat neocortex, hippocampus as well as spinal cord. |
2000-05-16 |
2023-08-12 |
rat |
| M J Schaaf, R Duurland, E R de Kloet, E Vreugdenhi. Circadian variation in BDNF mRNA expression in the rat hippocampus. Brain research. Molecular brain research. vol 75. issue 2. 2000-04-21. PMID:10686357. |
circadian variation in bdnf mrna expression in the rat hippocampus. |
2000-04-21 |
2023-08-12 |
rat |
| M J Schaaf, R Duurland, E R de Kloet, E Vreugdenhi. Circadian variation in BDNF mRNA expression in the rat hippocampus. Brain research. Molecular brain research. vol 75. issue 2. 2000-04-21. PMID:10686357. |
bdnf mrna levels in the hippocampus were studied during the circadian cycle by in situ hybridization. |
2000-04-21 |
2023-08-12 |
rat |
| G Fan, C Egles, Y Sun, L Minichiello, J J Renger, R Klein, G Liu, R Jaenisc. Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities. Nature neuroscience. vol 3. issue 4. 2000-04-21. PMID:10725924. |
although the bdnfnt4-ki/nt4-ki and wild-type bdnf+/+ alleles yielded similar levels of nt4 and bdnf proteins, nt4 supported more sensory neurons than bdnf and promoted functional synapse formation in cultured hippocampal neurons. |
2000-04-21 |
2023-08-12 |
mouse |
| C Aoki, K Wu, A Elste, G w Len, S y Lin, G McAuliffe, I B Blac. Localization of brain-derived neurotrophic factor and TrkB receptors to postsynaptic densities of adult rat cerebral cortex. Journal of neuroscience research. vol 59. issue 3. 2000-03-16. PMID:10679783. |
brain-derived neurotrophic factor (bdnf) rapidly increases synaptic transmission in hippocampal neurons, and enhances long-term potentiation (ltp), a cellular and molecular model of learning and memory. |
2000-03-16 |
2023-08-12 |
rat |