| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
studies show that during water maze training, corticosterone levels rise significantly, but the bdnf expression is not suppressed in any hippocampal subfield. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation. Stress (Amsterdam, Netherlands). vol 3. issue 3. 2000-09-15. PMID:10938581. |
therefore, we suggest that the resistance of the hippocampal bdnf expression to suppression by corticosterone, as seen after water maze training, may contribute to an optimal memory performance. |
2000-09-15 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
corticosterone effects on bdnf mrna expression in the rat hippocampus during morris water maze training. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
in the present study we have investigated the effect of corticosterone on hippocampal bdnf mrna expression after training in the morris water maze in young adult wistar rats. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
therefore, we first studied bdnf mrna levels in the hippocampus in relation to corticosterone levels at several time points after 4 training trials in the morris water maze. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
corticosterone levels were significantly increased after this procedure, and hippocampal bdnf mrna levels only displayed a minor change: an increase in ca1 at 1 hr after training. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
however, in a previous study we observed dramatically decreased hippocampal bdnf mrna levels in dentate gyrus and ca1 at 3 hr after injection of corticosterone. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
in order to analyze this discrepancy, we subsequently investigated if hippocampal bdnf mrna expression is affected by corticosterone at 3 hr after water maze training. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
adx animals which were subjected to water maze training displayed similar hippocampal bdnf mrna levels 3 hr after training compared to control adx animals. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
furthermore, adx animals which were injected with corticosterone showed decreased bdnf mrna levels in all hippocampal regions compared to control adx animals. |
2000-09-14 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
thus, the increased corticosterone levels during water maze training do not affect hippocampal bdnf mrna expression, although exogenous corticosterone is effective under these conditions. |
2000-09-14 |
2023-08-12 |
rat |
| M Takahashi, O Shirakawa, K Toyooka, N Kitamura, T Hashimoto, K Maeda, S Koizumi, K Wakabayashi, H Takahashi, T Someya, H Naw. Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients. Molecular psychiatry. vol 5. issue 3. 2000-09-12. PMID:10889532. |
among the neurotrophins examined, levels of brain-derived neurotrophic factor (bdnf) were elevated specifically in the anterior cingulate cortex and hippocampus of schizophrenic patients, but levels of nerve growth factors and neurotrophin-3 showed no change in any of the regions examined. |
2000-09-12 |
2023-08-12 |
human |
| M Takahashi, O Shirakawa, K Toyooka, N Kitamura, T Hashimoto, K Maeda, S Koizumi, K Wakabayashi, H Takahashi, T Someya, H Naw. Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients. Molecular psychiatry. vol 5. issue 3. 2000-09-12. PMID:10889532. |
in parallel, the expressions of trkb receptor and calbindin-d, which are both influenced by bdnf, were reduced significantly in the hippocampus or the prefrontal cortex. |
2000-09-12 |
2023-08-12 |
human |
| F Angelucci, A A Mathé, L Alo. Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration. Journal of neuroscience research. vol 60. issue 6. 2000-09-06. PMID:10861791. |
both haloperidol and risperidone significantly decreased bdnf concentrations in frontal cortex, occipital cortex and hippocampus and decreased or increased trkb receptors in selected brain structures. |
2000-09-06 |
2023-08-12 |
rat |
| M B Müller, N Toschi, A E Kresse, A Post, M E Kec. Long-term repetitive transcranial magnetic stimulation increases the expression of brain-derived neurotrophic factor and cholecystokinin mRNA, but not neuropeptide tyrosine mRNA in specific areas of rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 2. 2000-09-06. PMID:10882847. |
in situ hybridization revealed a significant increase in bdnf mrna in the hippocampal areas ca3 and ca3c, the granule cell layer, as well as in the parietal and the piriform cortex after rtms. |
2000-09-06 |
2023-08-12 |
rat |
| M B Heaton, J J Mitchell, M Paiva, D W Walke. Ethanol-induced alterations in the expression of neurotrophic factors in the developing rat central nervous system. Brain research. Developmental brain research. vol 121. issue 1. 2000-08-17. PMID:10837897. |
neonatal rats were exposed to ethanol throughout gestation, or during the early postnatal period (postnatal days 4-10 (p4-10)), and enzyme-linked immunoabsorbent assays were subsequently conducted in order to assess nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) protein content in hippocampus, septum, cortex/striatum and cerebellum. |
2000-08-17 |
2023-08-12 |
rat |
| M B Heaton, J J Mitchell, M Paiva, D W Walke. Ethanol-induced alterations in the expression of neurotrophic factors in the developing rat central nervous system. Brain research. Developmental brain research. vol 121. issue 1. 2000-08-17. PMID:10837897. |
following early postnatal exposure, bdnf was elevated in hippocampus and cortex/striatum (assessed on p10), and ngf was also enhanced in cortex/striatum at this age. |
2000-08-17 |
2023-08-12 |
rat |
| M B Heaton, J J Mitchell, M Paiva, D W Walke. Ethanol-induced alterations in the expression of neurotrophic factors in the developing rat central nervous system. Brain research. Developmental brain research. vol 121. issue 1. 2000-08-17. PMID:10837897. |
hippocampal and cortex/striatal bdnf returned to control levels by p21, but cortex/striatal ngf levels remained enhanced at this age. |
2000-08-17 |
2023-08-12 |
rat |
| D Liu, J Diorio, J C Day, D D Francis, M J Meane. Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nature neuroscience. vol 3. issue 8. 2000-08-15. PMID:10903573. |
thus, the offspring of mothers that show high levels of pup licking and grooming and arched-back nursing showed increased expression of nmda receptor subunit and brain-derived neurotrophic factor (bdnf) mrna, increased cholinergic innervation of the hippocampus and enhanced spatial learning and memory. |
2000-08-15 |
2023-08-12 |
rat |
| I Ferrer, E Goutan, C Marín, M J Rey, T Ribalt. Brain-derived neurotrophic factor in Huntington disease. Brain research. vol 866. issue 1-2. 2000-08-07. PMID:10825501. |
no modifications in bdnf expression levels have been seen in the parietal cortex, temporal cortex and hippocampus. |
2000-08-07 |
2023-08-12 |
human |