| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M I Davis, D Szarowski, J N Turner, R A Morrisett, W Shai. In vivo activation and in situ BDNF-stimulated nuclear translocation of mitogen-activated/extracellular signal-regulated protein kinase is inhibited by ethanol in the developing rat hippocampus. Neuroscience letters. vol 272. issue 2. 1999-11-24. PMID:10507550. |
brain-derived neurotrophic factor (bdnf) was used to stimulate erk in hippocampal slices prepared from pn5 pups and activation and cellular localization was determined with immunofluorescence combined with confocal microscopy. |
1999-11-24 |
2023-08-12 |
rat |
| K W Kafitz, C R Rose, H Thoenen, A Konnert. Neurotrophin-evoked rapid excitation through TrkB receptors. Nature. vol 401. issue 6756. 1999-11-24. PMID:10553907. |
even at low concentrations, brain-derived neurotrophic factor (bdnf) excited neurons in the hippocampus, cortex and cerebellum. |
1999-11-24 |
2023-08-12 |
Not clear |
| J Truettner, R Schmidt-Kastner, R Busto, O F Alonso, J Y Loor, W D Dietrich, M D Ginsber. Expression of brain-derived neurotrophic factor, nerve growth factor, and heat shock protein HSP70 following fluid percussion brain injury in rats. Journal of neurotrauma. vol 16. issue 6. 1999-11-23. PMID:10391364. |
bdnf was strongly upregulated in the granular cells of the dentate gyrus and in the ca3 hippocampus 2-6 h after injury. |
1999-11-23 |
2023-08-12 |
rat |
| L Aloe, F Properzi, L Probert, K Akassoglou, G Kassiotis, A Micera, M Fior. Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal. Brain research. vol 840. issue 1-2. 1999-11-22. PMID:10517960. |
bdnf levels were low in the hippocampus and spinal cord of tgk3. |
1999-11-22 |
2023-08-12 |
mouse |
| I Kiprianova, J Sandkühler, S Schwab, S Hoyer, M Sprange. Brain-derived neurotrophic factor improves long-term potentiation and cognitive functions after transient forebrain ischemia in the rat. Experimental neurology. vol 159. issue 2. 1999-11-19. PMID:10506522. |
we investigated the effect of brain-derived neurotrophic factor (bdnf) on hippocampal long-term potentiation (ltp) and cognitive functions after global cerebral ischemia in the rat. |
1999-11-19 |
2023-08-12 |
rat |
| A Russo-Neustadt, R C Beard, C W Cotma. Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 5. 1999-11-15. PMID:10516964. |
we have found that combined antidepressant treatment and physical activity have an additive, potentiating effect on bdnf mrna expression within several areas of the rat hippocampus. |
1999-11-15 |
2023-08-12 |
rat |
| A Russo-Neustadt, R C Beard, C W Cotma. Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 5. 1999-11-15. PMID:10516964. |
bdnf mrna levels were assessed in several cell groups of the hippocampus by in situ hybridization, using a [35s] labelled riboprobe complementary to the full-length bdnf sequence, and computer-assisted densitometry. |
1999-11-15 |
2023-08-12 |
rat |
| J Widenfalk, L Olson, P Thoré. Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain. Neuroscience research. vol 34. issue 3. 1999-11-10. PMID:10515254. |
we show that such long-distance running affects the brain-derived neurotrophic factor (bdnf) and trkb system in hippocampus, and in particular that abrupt deprivation of habitual running leads to long-lasting decreases of bdnf/trkb expression in hippocampus. |
1999-11-10 |
2023-08-12 |
rat |
| J Widenfalk, L Olson, P Thoré. Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain. Neuroscience research. vol 34. issue 3. 1999-11-10. PMID:10515254. |
quantitative in situ hybridization demonstrates that running increases the expression of mrna coding for bdnf and its high affinity receptor trkb in hippocampus in a running length dependent manner. |
1999-11-10 |
2023-08-12 |
rat |
| J Widenfalk, L Olson, P Thoré. Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain. Neuroscience research. vol 34. issue 3. 1999-11-10. PMID:10515254. |
in addition, we show that an abrupt interruption of prolonged spontaneous exercise decrease expression of mrna encoding bdnf and trkb in certain hippocampal areas and that this decrease lasts at least 10 days. |
1999-11-10 |
2023-08-12 |
rat |
| V Soontornniyomkij, G Wang, C A Pittman, R L Hamilton, C A Wiley, C L Achi. Absence of brain-derived neurotrophic factor and trkB receptor immunoreactivity in glia of Alzheimer's disease. Acta neuropathologica. vol 98. issue 4. 1999-11-05. PMID:10502038. |
in both groups, bdnf immunoreactivity was distributed in neuronal perikarya and neuritic processes in the neocortex and hippocampus. |
1999-11-05 |
2023-08-12 |
human |
| B Lu, A Cho. Neurotrophins and hippocampal synaptic transmission and plasticity. Journal of neuroscience research. vol 58. issue 1. 1999-11-04. PMID:10491573. |
in this review, we focus on the synaptic function of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
1999-11-04 |
2023-08-12 |
Not clear |
| B Lu, A Cho. Neurotrophins and hippocampal synaptic transmission and plasticity. Journal of neuroscience research. vol 58. issue 1. 1999-11-04. PMID:10491573. |
although a variety of in vitro experiments have shown the ability of bdnf to acutely modulate synaptic transmission, whether bdnf truly potentiates basal synaptic transmission in hippocampal neurons remains controversial. |
1999-11-04 |
2023-08-12 |
Not clear |
| B Lu, A Cho. Neurotrophins and hippocampal synaptic transmission and plasticity. Journal of neuroscience research. vol 58. issue 1. 1999-11-04. PMID:10491573. |
recent studies have begun to address the role of bdnf in late-phase ltp and in the development of hippocampal circuit. |
1999-11-04 |
2023-08-12 |
Not clear |
| M Walton, C Henderson, S Mason-Parker, P Lawlor, W C Abraham, D Bilkey, M Draguno. Immediate early gene transcription and synaptic modulation. Journal of neuroscience research. vol 58. issue 1. 1999-11-04. PMID:10491575. |
however, bdnf protein was not induced within the hippocampus after ltp and was transiently decreased following novel environmental stimulation. |
1999-11-04 |
2023-08-12 |
rat |
| Y L Ma, K Y Chen, C L Wei, E H Le. Corticotropin-releasing factor enhances brain-derived neurotrophic factor gene expression to facilitate memory retention in rats. The Chinese journal of physiology. vol 42. issue 2. 1999-11-02. PMID:10513602. |
in the present study, we investigated the effects of corticotropin-releasing factor (crf) injected into the dentate gyrus (dg) of the hippocampus on brain-derived neurotrophic factor (bdnf) mrna expression and studied whether n-methyl-d-aspartate (nmda) receptor mediates the effects of crf on bdnf mrna expression in the dg. |
1999-11-02 |
2023-08-12 |
rat |
| Y L Ma, K Y Chen, C L Wei, E H Le. Corticotropin-releasing factor enhances brain-derived neurotrophic factor gene expression to facilitate memory retention in rats. The Chinese journal of physiology. vol 42. issue 2. 1999-11-02. PMID:10513602. |
since both crf and bdnf gene expressions are involved in memory processing in rats, we further investigated whether crf facilitates memory retention through enhanced bdnf mrna expression in the hippocampus. |
1999-11-02 |
2023-08-12 |
rat |
| Y L Ma, K Y Chen, C L Wei, E H Le. Corticotropin-releasing factor enhances brain-derived neurotrophic factor gene expression to facilitate memory retention in rats. The Chinese journal of physiology. vol 42. issue 2. 1999-11-02. PMID:10513602. |
these results together suggest that at least one of the mechanisms responsible for the memory-facilitating effect of crf is mediated through enhanced bdnf mrna expression in the hippocampus. |
1999-11-02 |
2023-08-12 |
rat |
| B Berninger, A F Schinder, M M Po. Synaptic reliability correlates with reduced susceptibility to synaptic potentiation by brain-derived neurotrophic factor. Learning & memory (Cold Spring Harbor, N.Y.). vol 6. issue 3. 1999-10-19. PMID:10492005. |
recent studies have implicated brain-derived neurotrophic factor (bdnf) in use-dependent modification of hippocampal synapses. |
1999-10-19 |
2023-08-12 |
Not clear |
| B Berninger, A F Schinder, M M Po. Synaptic reliability correlates with reduced susceptibility to synaptic potentiation by brain-derived neurotrophic factor. Learning & memory (Cold Spring Harbor, N.Y.). vol 6. issue 3. 1999-10-19. PMID:10492005. |
using simultaneous perforated patch recording from pairs and triplets of glutamatergic hippocampal neurons, we have examined how the initial state of the glutamatergic synapse determines its susceptibility to synaptic modification by bdnf. |
1999-10-19 |
2023-08-12 |
Not clear |