| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
previous studies have suggested that the neurotrophins brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) are neuroprotective or neurotrophic for certain subpopulations of hippocampal neurons following various brain insults. |
1998-02-17 |
2023-08-12 |
rat |
| R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
in the present study, the expression of bdnf and nt-3 mrnas in rat hippocampus was examined after traumatic brain injury. |
1998-02-17 |
2023-08-12 |
rat |
| R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
a moderate increase in bdnf mrna expression was also observed bilaterally in the ca3 region of the hippocampus at 1, 3, and 6 h after fp injury, but expression declined to control levels by 24 h. conversely, nt-3 mrna was significantly decreased in the dentate gyrus following fp injury at the 6 and 24 h survival times. |
1998-02-17 |
2023-08-12 |
rat |
| R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
these results demonstrate that fp brain injury differentially modulates expression of bdnf and nt-3 mrnas in the hippocampus, and suggest that neurotrophin plasticity is a functional response of hippocampal neurons to brain trauma. |
1998-02-17 |
2023-08-12 |
rat |
| J T Bartrup, J M Moorman, N R Newberr. BDNF enhances neuronal growth and synaptic activity in hippocampal cell cultures. Neuroreport. vol 8. issue 17. 1998-02-17. PMID:9427372. |
bdnf enhances neuronal growth and synaptic activity in hippocampal cell cultures. |
1998-02-17 |
2023-08-12 |
rat |
| J T Bartrup, J M Moorman, N R Newberr. BDNF enhances neuronal growth and synaptic activity in hippocampal cell cultures. Neuroreport. vol 8. issue 17. 1998-02-17. PMID:9427372. |
brain-derived neurotrophic factor (bdnf) (20 ng/ml) significantly enhanced the growth of the somata of gaba-immunoreactive neurones in primary cultures of hippocampal neurones from postnatal rats after only 24h. |
1998-02-17 |
2023-08-12 |
rat |
| B Connor, D Young, Q Yan, R L Faull, B Synek, M Draguno. Brain-derived neurotrophic factor is reduced in Alzheimer's disease. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387865. |
these results support and extend previous findings that bdnf mrna is reduced in the human alzheimer's disease hippocampus and temporal cortex, and suggest that a loss of bdnf may contribute to the progressive atrophy of neurons in alzheimer's disease. |
1998-02-11 |
2023-08-12 |
human |
| A W Zhou, W X Li, J Guo, Y C D. Facilitation of AVP(4-8) on gene expression of BDNF and NGF in rat brain. Peptides. vol 18. issue 8. 1998-01-30. PMID:9396059. |
ngf and bdnf expression was found to be significantly enhanced by avp(4-8) administration in the cerebral cortex and hippocampus, but nt-3 expression was not changed. |
1998-01-30 |
2023-08-12 |
rat |
| N Kawahara, S D Croll, S J Wiegand, I Klatz. Cortical spreading depression induces long-term alterations of BDNF levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance. Neuroscience research. vol 29. issue 1. 1998-01-09. PMID:9293491. |
cortical spreading depression induces long-term alterations of bdnf levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance. |
1998-01-09 |
2023-08-12 |
Not clear |
| N Kawahara, S D Croll, S J Wiegand, I Klatz. Cortical spreading depression induces long-term alterations of BDNF levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance. Neuroscience research. vol 29. issue 1. 1998-01-09. PMID:9293491. |
in the hippocampus, bdnf protein levels showed a delayed decrease in both groups independent of mrna changes, but csd specifically delayed this decrease. |
1998-01-09 |
2023-08-12 |
Not clear |
| N Kawahara, S D Croll, S J Wiegand, I Klatz. Cortical spreading depression induces long-term alterations of BDNF levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance. Neuroscience research. vol 29. issue 1. 1998-01-09. PMID:9293491. |
bdnf could not, however, be directly related to ischemic tolerance in the hippocampus. |
1998-01-09 |
2023-08-12 |
Not clear |
| A Cellerino, P Carroll, H Thoenen, Y A Bard. Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor. Molecular and cellular neurosciences. vol 9. issue 5-6. 1998-01-08. PMID:9361277. |
intraventricular injections of bdnf into the ventricles of wild-type mice at p10 and p12 up-regulated expression of plp in the hippocampus at p14. |
1998-01-08 |
2023-08-12 |
mouse |
| E Tongiorgi, M Righi, A Cattane. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 24. 1998-01-07. PMID:9391005. |
activity-dependent dendritic targeting of bdnf and trkb mrnas in hippocampal neurons. |
1998-01-07 |
2023-08-12 |
Not clear |
| E Tongiorgi, M Righi, A Cattane. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 24. 1998-01-07. PMID:9391005. |
we show that in cultured hippocampal neurons, the mrnas for bdnf and trkb have a somatodendritic localization, and we quantify the extent of their dendritic mrna localization. |
1998-01-07 |
2023-08-12 |
Not clear |
| E Tongiorgi, M Righi, A Cattane. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 24. 1998-01-07. PMID:9391005. |
at the protein level, a brief stimulation of hippocampal neurons with 10 mm kcl leads to a marked increase of bdnf and trkb immunofluorescence density in the distal portion of dendrites, which also occurs, even if at lower levels, when transport is inhibited by nocodazole. |
1998-01-07 |
2023-08-12 |
Not clear |
| S Finkbeiner, S F Tavazoie, A Maloratsky, K M Jacobs, K M Harris, M E Greenber. CREB: a major mediator of neuronal neurotrophin responses. Neuron. vol 19. issue 5. 1997-12-29. PMID:9390517. |
to understand how neurotrophins elicit such diverse responses, we elucidated signaling pathways by which brain-derived neurotrophic factor (bdnf) activates gene expression in cultured neurons and hippocampal slices. |
1997-12-29 |
2023-08-12 |
Not clear |
| C R Jarvis, Z G Xiong, J R Plant, D Churchill, W Y Lu, B A MacVicar, J F MacDonal. Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons. Journal of neurophysiology. vol 78. issue 5. 1997-12-22. PMID:9356388. |
patch-clamp and calcium imaging techniques were used to assess the acute effects of the neurotrophins, brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), and nerve growth factor (ngf), on the responses of cultured and acutely isolated hippocampal and cultured striatal neurons to the glutamate receptor agonist n-methyl--aspartic acid (nmda). |
1997-12-22 |
2023-08-12 |
rat |
| C R Jarvis, Z G Xiong, J R Plant, D Churchill, W Y Lu, B A MacVicar, J F MacDonal. Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons. Journal of neurophysiology. vol 78. issue 5. 1997-12-22. PMID:9356388. |
bdnf also reversibly increased the probability of opening of nmda channels recorded from outside-out patches taken from cultured hippocampal neurons. |
1997-12-22 |
2023-08-12 |
rat |
| M A Smith, G Cizz. Stress-induced changes in brain-derived neurotrophic factor expression are attenuated in aged Fischer 344/N rats. Neurobiology of aging. vol 17. issue 6. 1997-12-04. PMID:9363796. |
the ability of acute immobilization stress (2 h) to modulate bdnf mrna levels in old rats was significantly reduced both in the hippocampus (a smaller decrease in bdnf) and the pvn (a smaller increase in bdnf) compared to young rats. |
1997-12-04 |
2023-08-12 |
rat |
| H Andersson, E Lindqvist, L Olso. Downregulation of brain-derived neurotrophic factor mRNA in adult rat brain after acute administration of methylmercury. Molecular and chemical neuropathology. vol 31. issue 3. 1997-11-26. PMID:9336765. |
decreases in brain-derived neurotrophic (bdnf) mrna labeling intensities were seen in the dentate gyrus (dg; 44% of controls), and in the ca1 (72% of controls) and ca3c (70% of controls) cell layers of hippocampus after 8 mg mehg/kg (ip) at 4 h, and at 1 h only in the dg. |
1997-11-26 |
2023-08-12 |
rat |