| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Andersson, E Lindqvist, L Olso. Downregulation of brain-derived neurotrophic factor mRNA in adult rat brain after acute administration of methylmercury. Molecular and chemical neuropathology. vol 31. issue 3. 1997-11-26. PMID:9336765. |
no significant changes could be detected in mrna levels of the bdnf high-affinity receptor trkb or neurotrophin-3 mrna at either 1 h, 4 h, or 3 d. cresyl violet staining and gfap immunohistochemistry did not reveal any major neuropathology in hippocampus at 2 wk. |
1997-11-26 |
2023-08-12 |
rat |
| P R Blanquet, Y Lamou. Brain-derived neurotrophic factor increases Ca2+/calmodulin-dependent protein kinase 2 activity in hippocampus. The Journal of biological chemistry. vol 272. issue 39. 1997-10-23. PMID:9305859. |
here we show that brain-derived neurotrophic factor (bdnf) stimulates both the phosphorylation of the ca2+/calmodulin-dependent protein kinase 2 (camk2) and its kinase activity in rat hippocampal slices. |
1997-10-23 |
2023-08-12 |
rat |
| H E Scharfma. Hyperexcitability in combined entorhinal/hippocampal slices of adult rat after exposure to brain-derived neurotrophic factor. Journal of neurophysiology. vol 78. issue 2. 1997-10-23. PMID:9307136. |
effects of brain-derived neurotrophic factor (bdnf) in area ca3, the dentate gyrus, and medial entorhinal cortex were examined electrophysiologically by bath application of bdnf in slices containing the hippocampus and entorhinal cortex. |
1997-10-23 |
2023-08-12 |
rat |
| Y K Kwo. Expression of brain-derived neurotrophic factor mRNA stimulated by basic fibroblast growth factor and platelet-derived growth factor in rat hippocampal cell line. Molecules and cells. vol 7. issue 3. 1997-10-06. PMID:9264017. |
bdnf mrna is expressed at high levels in hippocampus and bdnf serves as a trophic factor in primary cultures of rat hippocampus. |
1997-10-06 |
2023-08-12 |
rat |
| Y K Kwo. Expression of brain-derived neurotrophic factor mRNA stimulated by basic fibroblast growth factor and platelet-derived growth factor in rat hippocampal cell line. Molecules and cells. vol 7. issue 3. 1997-10-06. PMID:9264017. |
this report demonstrates that hib5 cells express a functionally active pdgf beta receptor and that pdgf and bfgf stimulate the expression of bdnf within 2 h. these results propose that bdnf is a candidate mediator of trophic effects of pdgf and bfgf in the hippocampal stem cell line hib5. |
1997-10-06 |
2023-08-12 |
rat |
| C A Willson, I Hani. Brain-derived neurotrophic factor induced stimulation of septal choline acetyltransferase activity in ethylcholine mustard aziridinium treated rats. Neuroscience letters. vol 229. issue 3. 1997-09-24. PMID:9237480. |
bdnf infusion (at a dose range of 0.1-171 microg) into either the lateral ventricle or hippocampus of af64a-treated rats for 14 days increased septal chat activity (26% and 41%, respectively). |
1997-09-24 |
2023-08-12 |
rat |
| C A Willson, I Hani. Brain-derived neurotrophic factor induced stimulation of septal choline acetyltransferase activity in ethylcholine mustard aziridinium treated rats. Neuroscience letters. vol 229. issue 3. 1997-09-24. PMID:9237480. |
bdnf did not reverse the decrease in hippocampal chat activity (20-60%) produced by af64a. |
1997-09-24 |
2023-08-12 |
rat |
| S Lee, J Williamson, E W Lothman, F G Szele, M F Chesselet, S Von Hagen, R M Sapolsky, M P Mattson, S Christako. Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment. Brain research. Molecular brain research. vol 47. issue 1-2. 1997-09-17. PMID:9221916. |
early induction of mrna for calbindin-d28k and bdnf but not nt-3 in rat hippocampus after kainic acid treatment. |
1997-09-17 |
2023-08-12 |
rat |
| S Lee, J Williamson, E W Lothman, F G Szele, M F Chesselet, S Von Hagen, R M Sapolsky, M P Mattson, S Christako. Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment. Brain research. Molecular brain research. vol 47. issue 1-2. 1997-09-17. PMID:9221916. |
the influence of kainic acid (ka), which induces acute seizures, on expression of mrna for the calcium-binding protein, calbindin-d28k, brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3) and early-response genes [c-fos, zif268 (ngfi-a), nur77 (ngfi-b)] was examined in rat hippocampus by northern blot analysis. |
1997-09-17 |
2023-08-12 |
rat |
| H Andersson, C Wetmore, E Lindqvist, J Luthman, L Olso. Trimethyltin exposure in the rat induces delayed changes in brain-derived neurotrophic factor, fos and heat shock protein 70. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9215997. |
no significant alterations in the bdnf mrna were detected in hippocampus and cerebral cortex 1 and 4 h after 8 mg tmt/kg. |
1997-09-09 |
2023-08-12 |
rat |
| H Andersson, C Wetmore, E Lindqvist, J Luthman, L Olso. Trimethyltin exposure in the rat induces delayed changes in brain-derived neurotrophic factor, fos and heat shock protein 70. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9215997. |
no significant change in bdnf immunoreactivity was seen in hippocampus or cerebral cortex 3 days after tmt. |
1997-09-09 |
2023-08-12 |
rat |
| H Andersson, E Lindqvist, L Olso. Plant-derived amino acids increase hippocampal BDNF, NGF, c-fos and hsp70 mRNAs. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223057. |
plant-derived amino acids increase hippocampal bdnf, ngf, c-fos and hsp70 mrnas. |
1997-08-29 |
2023-08-12 |
rat |
| H Andersson, E Lindqvist, L Olso. Plant-derived amino acids increase hippocampal BDNF, NGF, c-fos and hsp70 mRNAs. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223057. |
major increases in heat-shock protein 70, c-fos and brain-derived neurotrophic factor (bdnf) mrnas were seen in hippocampus 1 h after boaa or bmaa injections. |
1997-08-29 |
2023-08-12 |
rat |
| H Andersson, E Lindqvist, L Olso. Plant-derived amino acids increase hippocampal BDNF, NGF, c-fos and hsp70 mRNAs. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223057. |
four hours after bmaa injections increased hybridization to bdnf mrna was still seen in hippocampus, in parallel with reduced neurotrophin-3 expression in the dg. |
1997-08-29 |
2023-08-12 |
rat |
| M A Smith, L X Zhang, W E Lyons, L A Mamouna. Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223060. |
however, immunohistochemistry with an anti-bdnf antibody revealed that ecs increased endogenous bdnf protein in the mossy fibers, which are composed of axons projecting from the granule neurons of the dentate gyrus to the ca3 pyramidal layer of the hippocampus. |
1997-08-29 |
2023-08-12 |
Not clear |
| M A Smith, L X Zhang, W E Lyons, L A Mamouna. Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223060. |
three weeks later, a prolonged elevation of bdnf mrna in granule neurons, but not elsewhere in hippocampus, was accompanied by an increase in bdnf protein in the mossy fibers. |
1997-08-29 |
2023-08-12 |
Not clear |
| P C Suen, K Wu, E S Levine, H T Mount, J L Xu, S Y Lin, I B Blac. Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N-methyl-D-aspartate receptor subunit 1. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 15. 1997-08-27. PMID:9223337. |
in particular, brain-derived neurotrophic factor (bdnf) rapidly enhances synaptic transmission in hippocampal neurons through trkb receptor stimulation and postsynaptic phosphorylation mechanisms. |
1997-08-27 |
2023-08-12 |
Not clear |
| I Ferrer, J Ballabriga, E Martí, E Pozas, A M Planas, J Blas. BDNF and TrkB co-localize in CA1 neurons resistant to transient forebrain ischemia in the adult gerbil. Journal of neuropathology and experimental neurology. vol 56. issue 7. 1997-08-07. PMID:9210875. |
these results indicate that a subpopulation of ca1 hippocampal neurons coexpressing trkb, parvalbumin and bdnf is resistant to transient forebrain ischemia in the gerbil. |
1997-08-07 |
2023-08-12 |
Not clear |
| M Dragunow, P Hughes, S E Mason-Parker, P Lawlor, W C Abraha. TrkB expression in dentate granule cells is associated with a late phase of long-term potentiation. Brain research. Molecular brain research. vol 46. issue 1-2. 1997-08-05. PMID:9191102. |
recent studies have demonstrated that the neurotrophins nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) are induced in hippocampal neurons following the induction of long-term potentiation (ltp), a model of memory, and that bdnf and nt-3 (but not ngf) can induce ltp-like increases in synaptic efficacy. |
1997-08-05 |
2023-08-12 |
Not clear |
| M Dragunow, P Hughes, S E Mason-Parker, P Lawlor, W C Abraha. TrkB expression in dentate granule cells is associated with a late phase of long-term potentiation. Brain research. Molecular brain research. vol 46. issue 1-2. 1997-08-05. PMID:9191102. |
receptors for these neurotrophins have been cloned and characterized and we investigated whether ltp alters the expression of two neurotrophin receptors, trkb (bdnf receptor) and trkc (nt-3 receptor) in dentate granule neurons of the hippocampus using in situ hybridization analysis. |
1997-08-05 |
2023-08-12 |
Not clear |