| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Simonato, R Molteni, G Bregola, A Muzzolini, M Piffanelli, L Beani, G Racagni, M Riv. Different patterns of induction of FGF-2, FGF-1 and BDNF mRNAs during kindling epileptogenesis in the rat. The European journal of neuroscience. vol 10. issue 3. 1998-10-22. PMID:9753162. |
however, in contrast with the effect of a single stimulation, amygdala stimulation of kindled animals (evoking a generalized tonic-clonic seizure) produced a great increase in hippocampal and cortical bdnf mrna levels, but fgf-1 mrna levels were not altered, and fgf-2 mrna levels were significantly increased only in the cortex. |
1998-10-22 |
2023-08-12 |
rat |
| Y Yamasaki, T Shigeno, Y Furukawa, S Furukaw. Reduction in brain-derived neurotrophic factor protein level in the hippocampal CA1 dendritic field precedes the delayed neuronal damage in the rat brain. Journal of neuroscience research. vol 53. issue 3. 1998-10-21. PMID:9698160. |
utilizing a specific polyclonal antibody against a peptide unique for brain-derived neurotrophic factor (bdnf), we investigated the regional and temporal profiles of immunoreactivity of the bdnf protein in the rat hippocampus after transient forebrain ischemia. |
1998-10-21 |
2023-08-12 |
rat |
| R Bova, M R Micheli, P Qualadrucci, G G Zuccon. BDNF and trkB mRNAs oscillate in rat brain during the light-dark cycle. Brain research. Molecular brain research. vol 57. issue 2. 1998-10-20. PMID:9675430. |
in this study, we investigated whether in basal conditions the different functional states occurring during a 24-h cycle are reflected by the expression of brain-derived neurotrophic factor (bdnf) and its receptor, trkb, in rat cerebral cortex and hippocampus. |
1998-10-20 |
2023-08-12 |
rat |
| R Bova, M R Micheli, P Qualadrucci, G G Zuccon. BDNF and trkB mRNAs oscillate in rat brain during the light-dark cycle. Brain research. Molecular brain research. vol 57. issue 2. 1998-10-20. PMID:9675430. |
the strongest variation was detected in the hippocampus, where the ratio between maximum and minimum levels was about 3.5 and 17.5 for bdnf and trkb, respectively. |
1998-10-20 |
2023-08-12 |
rat |
| S Y Lin, K Wu, E S Levine, H T Mount, P C Suen, I B Blac. BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Brain research. Molecular brain research. vol 55. issue 1. 1998-10-09. PMID:9645956. |
bdnf acutely increases tyrosine phosphorylation of the nmda receptor subunit 2b in cortical and hippocampal postsynaptic densities. |
1998-10-09 |
2023-08-12 |
Not clear |
| S Y Lin, K Wu, E S Levine, H T Mount, P C Suen, I B Blac. BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Brain research. Molecular brain research. vol 55. issue 1. 1998-10-09. PMID:9645956. |
brain-derived neurotrophic factor (bdnf) enhances excitatory postsynaptic currents in cultured dissociated hippocampal neurons within 2-3 min through postsynaptic, phosphorylation-dependent mechanisms. |
1998-10-09 |
2023-08-12 |
Not clear |
| S Y Lin, K Wu, E S Levine, H T Mount, P C Suen, I B Blac. BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Brain research. Molecular brain research. vol 55. issue 1. 1998-10-09. PMID:9645956. |
moreover, bdnf modulates hippocampal long-term potentiation, in which postsynaptic nmda (n-methyl-d-aspartate) receptors (nrs) play a key role. |
1998-10-09 |
2023-08-12 |
Not clear |
| S Y Lin, K Wu, E S Levine, H T Mount, P C Suen, I B Blac. BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Brain research. Molecular brain research. vol 55. issue 1. 1998-10-09. PMID:9645956. |
incubation of bdnf with cortical or hippocampal postsynaptic densities for 5 min increased tyrosine phosphorylation of the nr2b subunits in a dose-dependent manner. |
1998-10-09 |
2023-08-12 |
Not clear |
| J C Lauterborn, F R Poulsen, C T Stinis, P J Isackson, C M Gal. Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus. Brain research. Molecular brain research. vol 55. issue 1. 1998-10-09. PMID:9645963. |
transcript-specific effects of adrenalectomy on seizure-induced bdnf expression in rat hippocampus. |
1998-10-09 |
2023-08-12 |
rat |
| J C Lauterborn, F R Poulsen, C T Stinis, P J Isackson, C M Gal. Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus. Brain research. Molecular brain research. vol 55. issue 1. 1998-10-09. PMID:9645963. |
exon-specific in situ hybridization was used to determine if adrenalectomy has differential effects on basal and activity-induced bdnf transcript expression in hippocampus. |
1998-10-09 |
2023-08-12 |
rat |
| Y X Li, Y Xu, D Ju, H A Lester, N Davidson, E M Schuma. Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 18. 1998-09-28. PMID:9724799. |
when expressed in the presynaptic cell at synapses between embryonic hippocampal neurons in culture, the dominant negative trkb.t1 inhibited two forms of synaptic potentiation induced by the neurotrophin brain-derived neurotrophic factor (bdnf): (i) greater evoked synaptic transmission and (ii) higher frequency of spontaneous miniature synaptic currents. |
1998-09-28 |
2023-08-12 |
Not clear |
| D K Song, B Choe, J H Bae, W K Park, I S Han, W K Ho, Y E Ear. Brain-derived neurotrophic factor rapidly potentiates synaptic transmission through NMDA, but suppresses it through non-NMDA receptors in rat hippocampal neuron. Brain research. vol 799. issue 1. 1998-09-11. PMID:9666119. |
brain-derived neurotrophic factor (bdnf) rapidly enhances synaptic transmission among the hippocampal neurons. |
1998-09-11 |
2023-08-12 |
rat |
| D K Song, B Choe, J H Bae, W K Park, I S Han, W K Ho, Y E Ear. Brain-derived neurotrophic factor rapidly potentiates synaptic transmission through NMDA, but suppresses it through non-NMDA receptors in rat hippocampal neuron. Brain research. vol 799. issue 1. 1998-09-11. PMID:9666119. |
in order to examine which component of glutamate receptors participates in synaptic potentiation by bdnf, we have studied the effect of glutamate antagonists on excitatory postsynaptic currents (epscs) enhanced by bdnf, using cultured embryonic hippocampal neurons. |
1998-09-11 |
2023-08-12 |
rat |
| D K Song, B Choe, J H Bae, W K Park, I S Han, W K Ho, Y E Ear. Brain-derived neurotrophic factor rapidly potentiates synaptic transmission through NMDA, but suppresses it through non-NMDA receptors in rat hippocampal neuron. Brain research. vol 799. issue 1. 1998-09-11. PMID:9666119. |
our results suggest that bdnf acutely activates synaptic transmission via nmda, but suppresses it via non-nmda receptors in the hippocampus. |
1998-09-11 |
2023-08-12 |
rat |
| W Gottschalk, L D Pozzo-Miller, A Figurov, B L. Presynaptic modulation of synaptic transmission and plasticity by brain-derived neurotrophic factor in the developing hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 17. 1998-09-09. PMID:9712654. |
application of brain-derived neurotrophic factor (bdnf) promotes long-term potentiation (ltp) in ca1 synapses of neonatal hippocampus, which otherwise exhibit only short-term potentiation. |
1998-09-09 |
2023-08-12 |
Not clear |
| A K Shetty, D A Turne. In vitro survival and differentiation of neurons derived from epidermal growth factor-responsive postnatal hippocampal stem cells: inducing effects of brain-derived neurotrophic factor. Journal of neurobiology. vol 35. issue 4. 1998-08-28. PMID:9624622. |
we investigated differentiation of stem cells from the postnatal mouse hippocampus in culture using the following trophic factors (20 ng/ml): brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3) and glial-derived neurotrophic factor (gdnf). |
1998-08-28 |
2023-08-12 |
mouse |
| A K Shetty, D A Turne. In vitro survival and differentiation of neurons derived from epidermal growth factor-responsive postnatal hippocampal stem cells: inducing effects of brain-derived neurotrophic factor. Journal of neurobiology. vol 35. issue 4. 1998-08-28. PMID:9624622. |
thus, bdnf supports survival of hippocampal stem cell-derived neurons and also can induce differentiation of these cells into pyramidal-like neurons. |
1998-08-28 |
2023-08-12 |
mouse |
| R Bender, B Heimrich, M Meyer, M Frotsche. Hippocampal mossy fiber sprouting is not impaired in brain-derived neurotrophic factor-deficient mice. Experimental brain research. vol 120. issue 3. 1998-08-27. PMID:9628426. |
this raised the possibility that bdnf is an important factor in hippocampal mossy fiber sprouting. |
1998-08-27 |
2023-08-12 |
mouse |
| S D Croll, C R Chesnutt, J S Rudge, A Acheson, T E Ryan, J A Siuciak, P S DiStefano, S J Wiegand, R M Lindsa. Co-infusion with a TrkB-Fc receptor body carrier enhances BDNF distribution in the adult rat brain. Experimental neurology. vol 152. issue 1. 1998-08-17. PMID:9682009. |
we co-infused trkb-fc with bdnf into the cortex and hippocampus of adult rats to determine whether trkb-fc would interfere with the ability of bdnf to upregulate neuropeptide y (npy). |
1998-08-17 |
2023-08-12 |
human |
| W Haubensak, F Narz, R Heumann, V Lessman. BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons. Journal of cell science. vol 111 ( Pt 11). 1998-07-28. PMID:9580557. |
we have now constructed a fusion protein consisting of n-terminal bdnf (the most abundant neurotrophin in the rodent hippocampus and neocortex) and c-terminal green fluorescent protein (gfp) to elucidate the cellular localization of bdnf in cortical neurons. |
1998-07-28 |
2023-08-12 |
rat |