| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
the effect of the 5-ht2a /2c receptor agonist on bdnf mrna in both the hippocampus and the neocortex was blocked by pretreatment with a selective 5-ht2a, but not 5-ht2c, receptor antagonist. |
1997-04-28 |
2023-08-12 |
Not clear |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
the expression of bdnf mrna in the hippocampus is reported to be decreased by stress, raising the possibility that the 5-ht2a receptor mediates this effect. |
1997-04-28 |
2023-08-12 |
Not clear |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
pretreatment with ketanserin, a 5-ht2a /2c receptor antagonist, significantly blocked the stress-induced downregulation of bdnf mrna in hippocampus, in support of this hypothesis. |
1997-04-28 |
2023-08-12 |
Not clear |
| V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
the results of this study raise the possibility that regulation of bdnf expression by hallucinogenic 5-ht2a receptor agonists leads to adaptations of synaptic strength in the hippocampus and the neocortex that may mediate some of the acute and long-term behavioral effects of these agents. |
1997-04-28 |
2023-08-12 |
Not clear |
| M Korte, V Staiger, O Griesbeck, H Thoenen, T Bonhoeffe. The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments. Journal of physiology, Paris. vol 90. issue 3-4. 1997-04-24. PMID:9116659. |
these results suggest that bdnf has an important functional role in the expression of ltp in the hippocampus. |
1997-04-24 |
2023-08-12 |
mouse |
| A Androutsellis-Theotokis, W J McCormack, H F Bradford, G M Stern, F B Pliego-River. The depolarisation-induced release of [125I]BDNF from brain tissue. Brain research. vol 743. issue 1-2. 1997-04-17. PMID:9017228. |
rat brain slices from cerebral cortex and synaptosomes from cerebral cortex and hippocampus were preloaded with [125i]bdnf. |
1997-04-17 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
synthesis of the neurotrophic factor brain-derived neurotrophic factor (bdnf) and its receptor trkb in the hippocampus have been proposed to be influenced by endogenous glutamate. |
1997-04-16 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
to test this hypothesis we have investigated if increases in bdnf and trkb mrnas are associated with changes in the synaptic release of glutamate in the dorsal hippocampus in the conscious rat by combining the technique of in vivo microdialysis with in situ hybridization histochemistry. |
1997-04-16 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
levels of bdnf and trkb mrnas were increased in the hippocampus in a dose-dependent fashion following the stimulations. |
1997-04-16 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
the extracellular levels of glutamate in individual animals correlated to the levels of bdnf and trkb mrnas in the dorsal ca1 region of the hippocampus. |
1997-04-16 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, F Camilli, M Metsis, U Ungersted. Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013789. |
this study provides for the first time evidence of an entorhinal cortex influenced concentration-dependent relationship between the release of endogenous glutamate in vivo and neuronal expression of mrnas for bdnf and its receptor trkb in the hippocampus. |
1997-04-16 |
2023-08-12 |
rat |
| J Zhou, B Pliego-Rivero, H F Bradford, G M Ster. The BDNF content of postnatal and adult rat brain: the effects of 6-hydroxydopamine lesions in adult brain. Brain research. Developmental brain research. vol 97. issue 2. 1997-04-15. PMID:8997515. |
increased levels of the bdnf were found in the hippocampus, cerebrocortex, striatum, cerebellum and ventral mesencephalon in 2-week-old rats, compared with that in postnatal day 0 pups. |
1997-04-15 |
2023-08-12 |
rat |
| J Zhou, B Pliego-Rivero, H F Bradford, G M Ster. The BDNF content of postnatal and adult rat brain: the effects of 6-hydroxydopamine lesions in adult brain. Brain research. Developmental brain research. vol 97. issue 2. 1997-04-15. PMID:8997515. |
in the adult rat, the highest level of bdnf was detected in the hippocampus (14.5 +/- 0.8 ng/g wet tissue), with a relatively high level also observed in the cerebrocortex and striatum. |
1997-04-15 |
2023-08-12 |
rat |
| M A Pelleymounter, M J Cullen, M B Baker, M Gollub, C Wellma. The effects of intrahippocampal BDNF and NGF on spatial learning in aged Long Evans rats. Molecular and chemical neuropathology. vol 29. issue 2-3. 1997-04-02. PMID:8971697. |
ngf, but not bdnf, improved spatial learning rate in aged rats and increased hippocampal choline uptake weeks after withdrawal of ngf. |
1997-04-02 |
2023-08-12 |
rat |
| Y Akaneya, T Tsumoto, H Hatanak. Brain-derived neurotrophic factor blocks long-term depression in rat visual cortex. Journal of neurophysiology. vol 76. issue 6. 1997-04-02. PMID:8985915. |
brain-derived neurotrophic factor (bdnf) has been reported to play a role in long-term potentiation (ltp) in hippocampus, but whether it is involved also in long-term depression (ltd) is not yet known. |
1997-04-02 |
2023-08-12 |
rat |
| Y Dimberg, M Vazquez, S Söderström, T Ebenda. Effects of X-irradiation on nerve growth factor in the developing mouse brain. Toxicology letters. vol 90. issue 1. 1997-02-27. PMID:9020400. |
nerve growth factor protein (ngf) and different cholinergic markers were investigated on postnatal day 1 (p1) and day 21 (p21); in situ hybridization with brain-derived neurotrophic factor (bdnf) and trkc (receptor serving to bind neurotrophin-3) probes was investigated on p21 in cortex, hippocampus, septum and cerebellum. |
1997-02-27 |
2023-08-12 |
mouse |
| M Reeben, J Arbatova, J Palgi, R Miettinen, M Halmekytö, L Alhonen, J Jänne, P Riekkinen, M Saarm. Induced expression of neurotrophins in transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine. Journal of neuroscience research. vol 45. issue 5. 1997-02-18. PMID:8875319. |
northern blot analysis indicated that mrna levels of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf) and neurotrophin-3 (nt-3) were significantly elevated about 1.5-fold in the hippocampus of odc transgenic mice as compared with control animals. |
1997-02-18 |
2023-08-12 |
mouse |
| S A Neeper, F Gómez-Pinilla, J Choi, C W Cotma. Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain research. vol 726. issue 1-2. 1997-02-13. PMID:8836544. |
bdnf mrna was significantly increased in several brain areas, most notably in the hippocampus and caudal 1/3 of cerebral cortex following 2, 4, and 7 nights with exercise. |
1997-02-13 |
2023-08-12 |
rat |
| S A Neeper, F Gómez-Pinilla, J Choi, C W Cotma. Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain research. vol 726. issue 1-2. 1997-02-13. PMID:8836544. |
significant elevations in bdnf mrna were localized in ammon's horn areas 1 (ca1) and 4 (ca4) of the hippocampus, and layers ii-iii of the caudal neocortex and retrosplenial cortex. |
1997-02-13 |
2023-08-12 |
rat |
| O Zachrisson, T Falkenberg, N Lindefor. Neuronal coexistence of trkB and glutamic acid decarboxylase67 mRNAs in rat hippocampus. Brain research. Molecular brain research. vol 36. issue 1. 1997-02-06. PMID:9011754. |
we have in earlier studies shown that brain derived neurotrophic factor (bdnf) mrna expression is increased in the hippocampus following stimulation of excitatory cortical afferents and spatial learning. |
1997-02-06 |
2023-08-12 |
rat |