Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Y Nakagami, H Saito, N Matsuk. Basic fibroblast growth factor and brain-derived neurotrophic factor promote survival and neuronal circuit formation in organotypic hippocampal culture. Japanese journal of pharmacology. vol 75. issue 4. 1998-03-24. PMID:9469637. |
optical recording also demonstrated that addition of 10 ng/ml bfgf or 50 ng/ml bdnf enhanced optical signals in all hippocampal areas significantly. |
1998-03-24 |
2023-08-12 |
Not clear |
Y Nakagami, H Saito, N Matsuk. Basic fibroblast growth factor and brain-derived neurotrophic factor promote survival and neuronal circuit formation in organotypic hippocampal culture. Japanese journal of pharmacology. vol 75. issue 4. 1998-03-24. PMID:9469637. |
these data strongly suggest that bfgf and bdnf promote the formation of neuronal circuits as well as survival and that optical recording of organotypic hippocampal slices would be a useful technique that enables us to analyze neuronal circuit formation easily. |
1998-03-24 |
2023-08-12 |
Not clear |
T F Hsieh, S Simler, M Vergnes, P Gass, C Marescaux, S J Wiegand, M Zimmermann, T Herdege. BDNF restores the expression of Jun and Fos inducible transcription factors in the rat brain following repetitive electroconvulsive seizures. Experimental neurology. vol 149. issue 1. 1998-03-06. PMID:9454625. |
in order to study the maintenance of c-fos expression during repetitive seizures, brain-derived neurotrophic factor (bdnf) was applied in parallel for 5 or 10 days via miniosmotic pumps and permanent cannula targeted at the hippocampus or the parietal cortex. |
1998-03-06 |
2023-08-12 |
rat |
T F Hsieh, S Simler, M Vergnes, P Gass, C Marescaux, S J Wiegand, M Zimmermann, T Herdege. BDNF restores the expression of Jun and Fos inducible transcription factors in the rat brain following repetitive electroconvulsive seizures. Experimental neurology. vol 149. issue 1. 1998-03-06. PMID:9454625. |
bdnf had no effect on the expression patterns in the hippocampus. |
1998-03-06 |
2023-08-12 |
rat |
N Sakai, M Yamada, T Numakawa, A Ogura, H Hatanak. BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons. Brain research. vol 778. issue 2. 1998-03-03. PMID:9459549. |
bdnf potentiates spontaneous ca2+ oscillations in cultured hippocampal neurons. |
1998-03-03 |
2023-08-12 |
rat |
N Sakai, M Yamada, T Numakawa, A Ogura, H Hatanak. BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons. Brain research. vol 778. issue 2. 1998-03-03. PMID:9459549. |
we monitored changes in the intracellular calcium (ca2+) levels induced by bdnf using a fluorescence ca2+ indicator (fluo-3) by means of confocal laser microscopy in rat cultured hippocampal neurons. |
1998-03-03 |
2023-08-12 |
rat |
N Sakai, M Yamada, T Numakawa, A Ogura, H Hatanak. BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons. Brain research. vol 778. issue 2. 1998-03-03. PMID:9459549. |
bdnf may have the potential to modulate spontaneous ca2+ oscillations to regulate neuronal plasticity in developing hippocampal neurons. |
1998-03-03 |
2023-08-12 |
rat |
A Kadari, J M Windisch, T Ebendal, R Schneider, C Humpe. Cell death of adult pyramidal CA1 neurons after intraventricular injection of a novel peptide derived from trkA. Journal of neuroscience research. vol 50. issue 3. 1998-02-19. PMID:9364325. |
since the highest concentration of neurotrophins [ngf, brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3)] is found in the hippocampus, the peptides were injected into the 3rd ventricle of anesthetized adult rats. |
1998-02-19 |
2023-08-12 |
rat |
R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
alterations in bdnf and nt-3 mrnas in rat hippocampus after experimental brain trauma. |
1998-02-17 |
2023-08-12 |
rat |
R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
previous studies have suggested that the neurotrophins brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) are neuroprotective or neurotrophic for certain subpopulations of hippocampal neurons following various brain insults. |
1998-02-17 |
2023-08-12 |
rat |
R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
in the present study, the expression of bdnf and nt-3 mrnas in rat hippocampus was examined after traumatic brain injury. |
1998-02-17 |
2023-08-12 |
rat |
R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
a moderate increase in bdnf mrna expression was also observed bilaterally in the ca3 region of the hippocampus at 1, 3, and 6 h after fp injury, but expression declined to control levels by 24 h. conversely, nt-3 mrna was significantly decreased in the dentate gyrus following fp injury at the 6 and 24 h survival times. |
1998-02-17 |
2023-08-12 |
rat |
R R Hicks, S Numan, H S Dhillon, M R Prasad, K B Seroog. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332737. |
these results demonstrate that fp brain injury differentially modulates expression of bdnf and nt-3 mrnas in the hippocampus, and suggest that neurotrophin plasticity is a functional response of hippocampal neurons to brain trauma. |
1998-02-17 |
2023-08-12 |
rat |
J T Bartrup, J M Moorman, N R Newberr. BDNF enhances neuronal growth and synaptic activity in hippocampal cell cultures. Neuroreport. vol 8. issue 17. 1998-02-17. PMID:9427372. |
bdnf enhances neuronal growth and synaptic activity in hippocampal cell cultures. |
1998-02-17 |
2023-08-12 |
rat |
J T Bartrup, J M Moorman, N R Newberr. BDNF enhances neuronal growth and synaptic activity in hippocampal cell cultures. Neuroreport. vol 8. issue 17. 1998-02-17. PMID:9427372. |
brain-derived neurotrophic factor (bdnf) (20 ng/ml) significantly enhanced the growth of the somata of gaba-immunoreactive neurones in primary cultures of hippocampal neurones from postnatal rats after only 24h. |
1998-02-17 |
2023-08-12 |
rat |
B Connor, D Young, Q Yan, R L Faull, B Synek, M Draguno. Brain-derived neurotrophic factor is reduced in Alzheimer's disease. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387865. |
these results support and extend previous findings that bdnf mrna is reduced in the human alzheimer's disease hippocampus and temporal cortex, and suggest that a loss of bdnf may contribute to the progressive atrophy of neurons in alzheimer's disease. |
1998-02-11 |
2023-08-12 |
human |
A W Zhou, W X Li, J Guo, Y C D. Facilitation of AVP(4-8) on gene expression of BDNF and NGF in rat brain. Peptides. vol 18. issue 8. 1998-01-30. PMID:9396059. |
ngf and bdnf expression was found to be significantly enhanced by avp(4-8) administration in the cerebral cortex and hippocampus, but nt-3 expression was not changed. |
1998-01-30 |
2023-08-12 |
rat |
N Kawahara, S D Croll, S J Wiegand, I Klatz. Cortical spreading depression induces long-term alterations of BDNF levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance. Neuroscience research. vol 29. issue 1. 1998-01-09. PMID:9293491. |
cortical spreading depression induces long-term alterations of bdnf levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance. |
1998-01-09 |
2023-08-12 |
Not clear |
N Kawahara, S D Croll, S J Wiegand, I Klatz. Cortical spreading depression induces long-term alterations of BDNF levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance. Neuroscience research. vol 29. issue 1. 1998-01-09. PMID:9293491. |
in the hippocampus, bdnf protein levels showed a delayed decrease in both groups independent of mrna changes, but csd specifically delayed this decrease. |
1998-01-09 |
2023-08-12 |
Not clear |
N Kawahara, S D Croll, S J Wiegand, I Klatz. Cortical spreading depression induces long-term alterations of BDNF levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance. Neuroscience research. vol 29. issue 1. 1998-01-09. PMID:9293491. |
bdnf could not, however, be directly related to ischemic tolerance in the hippocampus. |
1998-01-09 |
2023-08-12 |
Not clear |