Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
H Andersson, E Lindqvist, L Olso. Plant-derived amino acids increase hippocampal BDNF, NGF, c-fos and hsp70 mRNAs. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223057. |
plant-derived amino acids increase hippocampal bdnf, ngf, c-fos and hsp70 mrnas. |
1997-08-29 |
2023-08-12 |
rat |
H Andersson, E Lindqvist, L Olso. Plant-derived amino acids increase hippocampal BDNF, NGF, c-fos and hsp70 mRNAs. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223057. |
major increases in heat-shock protein 70, c-fos and brain-derived neurotrophic factor (bdnf) mrnas were seen in hippocampus 1 h after boaa or bmaa injections. |
1997-08-29 |
2023-08-12 |
rat |
H Andersson, E Lindqvist, L Olso. Plant-derived amino acids increase hippocampal BDNF, NGF, c-fos and hsp70 mRNAs. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223057. |
four hours after bmaa injections increased hybridization to bdnf mrna was still seen in hippocampus, in parallel with reduced neurotrophin-3 expression in the dg. |
1997-08-29 |
2023-08-12 |
rat |
M A Smith, L X Zhang, W E Lyons, L A Mamouna. Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223060. |
however, immunohistochemistry with an anti-bdnf antibody revealed that ecs increased endogenous bdnf protein in the mossy fibers, which are composed of axons projecting from the granule neurons of the dentate gyrus to the ca3 pyramidal layer of the hippocampus. |
1997-08-29 |
2023-08-12 |
Not clear |
M A Smith, L X Zhang, W E Lyons, L A Mamouna. Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223060. |
three weeks later, a prolonged elevation of bdnf mrna in granule neurons, but not elsewhere in hippocampus, was accompanied by an increase in bdnf protein in the mossy fibers. |
1997-08-29 |
2023-08-12 |
Not clear |
P C Suen, K Wu, E S Levine, H T Mount, J L Xu, S Y Lin, I B Blac. Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N-methyl-D-aspartate receptor subunit 1. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 15. 1997-08-27. PMID:9223337. |
in particular, brain-derived neurotrophic factor (bdnf) rapidly enhances synaptic transmission in hippocampal neurons through trkb receptor stimulation and postsynaptic phosphorylation mechanisms. |
1997-08-27 |
2023-08-12 |
Not clear |
I Ferrer, J Ballabriga, E Martí, E Pozas, A M Planas, J Blas. BDNF and TrkB co-localize in CA1 neurons resistant to transient forebrain ischemia in the adult gerbil. Journal of neuropathology and experimental neurology. vol 56. issue 7. 1997-08-07. PMID:9210875. |
these results indicate that a subpopulation of ca1 hippocampal neurons coexpressing trkb, parvalbumin and bdnf is resistant to transient forebrain ischemia in the gerbil. |
1997-08-07 |
2023-08-12 |
Not clear |
M Dragunow, P Hughes, S E Mason-Parker, P Lawlor, W C Abraha. TrkB expression in dentate granule cells is associated with a late phase of long-term potentiation. Brain research. Molecular brain research. vol 46. issue 1-2. 1997-08-05. PMID:9191102. |
recent studies have demonstrated that the neurotrophins nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) are induced in hippocampal neurons following the induction of long-term potentiation (ltp), a model of memory, and that bdnf and nt-3 (but not ngf) can induce ltp-like increases in synaptic efficacy. |
1997-08-05 |
2023-08-12 |
Not clear |
M Dragunow, P Hughes, S E Mason-Parker, P Lawlor, W C Abraha. TrkB expression in dentate granule cells is associated with a late phase of long-term potentiation. Brain research. Molecular brain research. vol 46. issue 1-2. 1997-08-05. PMID:9191102. |
receptors for these neurotrophins have been cloned and characterized and we investigated whether ltp alters the expression of two neurotrophin receptors, trkb (bdnf receptor) and trkc (nt-3 receptor) in dentate granule neurons of the hippocampus using in situ hybridization analysis. |
1997-08-05 |
2023-08-12 |
Not clear |
R Katoh-Semba, I K Takeuchi, R Semba, K Kat. Distribution of brain-derived neurotrophic factor in rats and its changes with development in the brain. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202291. |
in the rat brain at 1 month of age, the highest level of bdnf was detected in the hippocampus (5.41 ng/g of wet weight), followed by the hypothalamus (4.23 ng/g) and the septum (1.68 ng/g). |
1997-07-24 |
2023-08-12 |
human |
R Katoh-Semba, I K Takeuchi, R Semba, K Kat. Distribution of brain-derived neurotrophic factor in rats and its changes with development in the brain. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202291. |
the subfractionation of the hippocampal homogenate indicated that approximately 50% of bdnf was contained in the crude nuclear fraction. |
1997-07-24 |
2023-08-12 |
human |
R Katoh-Semba, I K Takeuchi, R Semba, K Kat. Distribution of brain-derived neurotrophic factor in rats and its changes with development in the brain. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202291. |
immunoblots of bdnf-immunoreactive proteins extracted from the hippocampus, hypothalamus, and cerebellum contained doublet bands of protein of approximately 14 kda, a value close to the molecular mass of recombinant human bdnf. |
1997-07-24 |
2023-08-12 |
human |
R Katoh-Semba, I K Takeuchi, R Semba, K Kat. Distribution of brain-derived neurotrophic factor in rats and its changes with development in the brain. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202291. |
immunocytochemical investigations showed that, in the hippocampus, bdnf was localized in the nucleus of the granule cells in the dentate gyrus and of the cells in the pyramidal cell layer. |
1997-07-24 |
2023-08-12 |
human |
M J Schaaf, R W Hoetelmans, E R de Kloet, E Vreugdenhi. Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus. Journal of neuroscience research. vol 48. issue 4. 1997-07-21. PMID:9169859. |
corticosterone regulates expression of bdnf and trkb but not nt-3 and trkc mrna in the rat hippocampus. |
1997-07-21 |
2023-08-12 |
rat |
M J Schaaf, R W Hoetelmans, E R de Kloet, E Vreugdenhi. Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus. Journal of neuroscience research. vol 48. issue 4. 1997-07-21. PMID:9169859. |
for this purpose we injected 30, 300, and 1,000 microg corticosterone s.c. (per kg body weight) in adrenalectomized rats and measured the mrna levels of brain-derived neurotrophic factor (bdnf), tyrosine receptor kinase (trk)b, neurotrophin (nt)-3, and trkc in hippocampal cell fields at 6 hr after steroid administration by in situ hybridization. |
1997-07-21 |
2023-08-12 |
rat |
M J Schaaf, R W Hoetelmans, E R de Kloet, E Vreugdenhi. Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus. Journal of neuroscience research. vol 48. issue 4. 1997-07-21. PMID:9169859. |
in conclusion, we found differential effects of low and high doses of corticosterone on bdnf and trkb expression in hippocampus, which suggests involvement of a coordinated mr- and gr-mediated action. |
1997-07-21 |
2023-08-12 |
rat |
S Marty, Berzaghi MdaP, B Berninge. Neurotrophins and activity-dependent plasticity of cortical interneurons. Trends in neurosciences. vol 20. issue 5. 1997-07-10. PMID:9141194. |
in the neocortex and hippocampus, bdnf is synthesized and secreted in an activity-dependent manner by pyramidal neurons, the target cells of gaba-containing neurons, suggesting that bdnf is an activity-dependent, target-derived trophic factor for these interneurons. |
1997-07-10 |
2023-08-12 |
mouse |
H I Kornblum, R Sankar, D H Shin, C G Wasterlain, C M Gal. Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. Brain research. Molecular brain research. vol 44. issue 2. 1997-07-08. PMID:9073163. |
in developing brain, lithium/pilocarpine induced elevations of bdnf mrna in the hippocampus, piriform and entorhinal cortex as early as postnatal day 7 (p7). |
1997-07-08 |
2023-08-12 |
rat |
A Montkowski, F Holsboe. Intact spatial learning and memory in transgenic mice with reduced BDNF. Neuroreport. vol 8. issue 3. 1997-07-03. PMID:9106766. |
because brain-derived neurotrophic factor (bdnf) had been shown to have a role in activity-dependent neuroplasticity in the hippocampus we studied spatial learning in mice with bdnf deficiency produced by gene-targeted mutation. |
1997-07-03 |
2023-08-12 |
mouse |
W R Schäbitz, S Schwab, M Spranger, W Hack. Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 17. issue 5. 1997-07-01. PMID:9183287. |
brain-derived neurotrophic factor (bdnf), acting through the high-affinity receptor tyrosine kinase (trkb), is widely distributed throughout the central nervous system and displays in vitro trophic effects on a wide range of neuronal cells, including hippocampal, cerebellar, and cortical neurons. |
1997-07-01 |
2023-08-12 |
rat |