| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L J Goodman, J Valverde, F Lim, M D Geschwind, H J Federoff, A I Geller, F Heft. Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons. Molecular and cellular neurosciences. vol 7. issue 3. 1996-11-05. PMID:8726105. |
immunocytochemical analysis using highly specific antibodies determined that endogenous bdnf was predominantly localized to the somatodentritic domain of hippocampal neurons. |
1996-11-05 |
2023-08-12 |
mouse |
| L J Goodman, J Valverde, F Lim, M D Geschwind, H J Federoff, A I Geller, F Heft. Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons. Molecular and cellular neurosciences. vol 7. issue 3. 1996-11-05. PMID:8726105. |
these findings support the view that bdnf functions as a target-derived signal for afferents to hippocampal pyramidal cells and that it may serve as a regulator of hippocampal plasticity. |
1996-11-05 |
2023-08-12 |
mouse |
| R Schmidt-Kastner, C Humpel, C Wetmore, L Olso. Cellular hybridization for BDNF, trkB, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus. Experimental brain research. vol 107. issue 3. 1996-10-30. PMID:8821376. |
bdnf mrna increased in hippocampus, neocortex, piriform cortex, striatum, and thalamus with a maximum at 3-6 h. hybridization levels increased earlier in the resistant granule and ca1 cells as compared to the vulnerable ca3 neurons. |
1996-10-30 |
2023-08-12 |
rat |
| R Schmidt-Kastner, C Humpel, C Wetmore, L Olso. Cellular hybridization for BDNF, trkB, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus. Experimental brain research. vol 107. issue 3. 1996-10-30. PMID:8821376. |
bdnf immunoreactivity was elevated in dentate gyrus at 3-6 h. trkb mrna increased in the entire hippocampus. |
1996-10-30 |
2023-08-12 |
rat |
| M Narisawa-Saito, H Naw. Differential regulation of hippocampal neurotrophins during aging in rats. Journal of neurochemistry. vol 67. issue 3. 1996-10-02. PMID:8752119. |
we used sensitive and specific two-site enzyme immunoassays to assess age-associated changes in levels of three neurotrophins++-+-nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), and neurotrophin-3 (nt-3)--in the hippocampus of fischer 344 rats. |
1996-10-02 |
2023-08-12 |
rat |
| M Narisawa-Saito, H Naw. Differential regulation of hippocampal neurotrophins during aging in rats. Journal of neurochemistry. vol 67. issue 3. 1996-10-02. PMID:8752119. |
more than 200 ng of bdnf per gram of tissue was detected in the hippocampus of 2-month-old rats. |
1996-10-02 |
2023-08-12 |
rat |
| H Kang, E M Schuma. A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. Science (New York, N.Y.). vol 273. issue 5280. 1996-10-01. PMID:8703078. |
two neurotrophic factors, brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3), are able to produce a long-lasting enhancement of synaptic transmission in the hippocampus. |
1996-10-01 |
2023-08-12 |
rat |
| K Yang, J R Perez-Polo, X S Mu, H Q Yan, J J Xue, Y Iwamoto, S J Liu, C E Dixon, R L Haye. Increased expression of brain-derived neurotrophic factor but not neurotrophin-3 mRNA in rat brain after cortical impact injury. Journal of neuroscience research. vol 44. issue 2. 1996-09-26. PMID:8723224. |
bdnf mrna increased at 1,3, and 5 hr after unilateral cortical injury in the cortex ipsilateral to the injury site and bilaterally in the dorsal hippocampus. |
1996-09-26 |
2023-08-12 |
rat |
| S Marty, B Berninger, P Carroll, H Thoene. GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron. vol 16. issue 3. 1996-09-20. PMID:8785053. |
gamma-aminobutyric acid (gaba) switches from enhancing to repressing brain-derived neurotrophic factor (bdnf) mrna synthesis during the maturation of hippocampal neurons in vitro. |
1996-09-20 |
2023-08-12 |
Not clear |
| S Marty, B Berninger, P Carroll, H Thoene. GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron. vol 16. issue 3. 1996-09-20. PMID:8785053. |
therefore, the question arose whether hippocampal interneurons regulate their phenotype by regulating bdnf expression and release from adjacent cells. |
1996-09-20 |
2023-08-12 |
Not clear |
| S Marty, B Berninger, P Carroll, H Thoene. GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron. vol 16. issue 3. 1996-09-20. PMID:8785053. |
the gaba(a) receptor agonist muscimol and bdnf increased the size and neuropeptide y (npy) immunoreactivity of hippocampal interneurons. |
1996-09-20 |
2023-08-12 |
Not clear |
| M Draguno. A role for immediate-early transcription factors in learning and memory. Behavior genetics. vol 26. issue 3. 1996-09-18. PMID:8754252. |
the ltp studies suggest that synaptic modifications occurring during nmda-receptor-mediated hippocampal ltp and ltd are stabilized by the protein products of the krox family of iegs (as well as by brain-derived neurotrophic factor, bdnf). |
1996-09-18 |
2023-08-12 |
Not clear |
| N Rocamora, E Welker, M Pascual, E Sorian. Upregulation of BDNF mRNA expression in the barrel cortex of adult mice after sensory stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 14. 1996-08-30. PMID:8699252. |
upregulation of brain-derived neurotrophic factor (bdnf) mrna expression by neuronal activity has been reported in cultured hippocampal cells and in different in vivo excitotoxic paradigms. |
1996-08-30 |
2023-08-12 |
mouse |
| S L Patterson, T Abel, T A Deuel, K C Martin, J C Rose, E R Kande. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. vol 16. issue 6. 1996-08-02. PMID:8663990. |
recombinant bdnf rescues deficits in basal synaptic transmission and hippocampal ltp in bdnf knockout mice. |
1996-08-02 |
2023-08-12 |
mouse |
| S L Patterson, T Abel, T A Deuel, K C Martin, J C Rose, E R Kande. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. vol 16. issue 6. 1996-08-02. PMID:8663990. |
brain-derived neurotrophic factor (bdnf) is expressed at high levels in hippocampal neurons, and its expression is modulated by neural activity. |
1996-08-02 |
2023-08-12 |
mouse |
| S L Patterson, T Abel, T A Deuel, K C Martin, J C Rose, E R Kande. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. vol 16. issue 6. 1996-08-02. PMID:8663990. |
we here demonstrate that treatment of hippocampal slices from bdnf knockout mice with recombinant bdnf completely reverses deficits in long-term potentiation and significantly improves deficits in basal synaptic transmission at the schaffer collateral-ca1 synapse. |
1996-08-02 |
2023-08-12 |
mouse |
| S L Patterson, T Abel, T A Deuel, K C Martin, J C Rose, E R Kande. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. vol 16. issue 6. 1996-08-02. PMID:8663990. |
thus, bdnf has an acute role in hippocampal synaptic function. |
1996-08-02 |
2023-08-12 |
mouse |
| N Rocamora, M Pascual, L Acsàdy, L de Lecea, T F Freund, E Sorian. Expression of NGF and NT3 mRNAs in hippocampal interneurons innervated by the GABAergic septohippocampal pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 12. 1996-07-30. PMID:8656293. |
we used in situ hybridization for the detection of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), and neurotrophin 3 (nt3) mrnas combined with immunocytochemistry against the calcium-binding proteins parvalbumin (parv), calbindin 28k (calb), and calretinin (calr) to determine the expression of neurotrophins in functionally distinct subsets of hippocampal interneurons. |
1996-07-30 |
2023-08-12 |
Not clear |
| N Rocamora, M Pascual, L Acsàdy, L de Lecea, T F Freund, E Sorian. Expression of NGF and NT3 mRNAs in hippocampal interneurons innervated by the GABAergic septohippocampal pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 12. 1996-07-30. PMID:8656293. |
small subsets of parv- and calr-positive cells expressed nt3 mrna, but we did not find hippocampal interneurons expressing bdnf mrna. |
1996-07-30 |
2023-08-12 |
Not clear |
| A Figurov, L D Pozzo-Miller, P Olafsson, T Wang, B L. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. vol 381. issue 6584. 1996-07-25. PMID:8649517. |
in developing hippocampus, the expression of brain derived neurotrophic factor (bdnf) and its receptor trkb increases in parallel with the ability to undergo long-term potentiation (ltp). |
1996-07-25 |
2023-08-12 |
Not clear |