| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Greg L West, Kyoko Konishi, Kathleen MacDonald, Anjie Ni, Ridha Joober, Veronique D Bohbo. The BDNF val66met polymorphism is associated with decreased use of landmarks and decreased fMRI activity in the hippocampus during virtual navigation. The European journal of neuroscience. vol 54. issue 7. 2021-11-01. PMID:34467592. |
the val66met polymorphism of the brain-derived neurotrophic factor (bdnf) gene leads to decreased secretion of bdnf in the brain, including the hippocampus. |
2021-11-01 |
2023-08-13 |
human |
| Greg L West, Kyoko Konishi, Kathleen MacDonald, Anjie Ni, Ridha Joober, Veronique D Bohbo. The BDNF val66met polymorphism is associated with decreased use of landmarks and decreased fMRI activity in the hippocampus during virtual navigation. The European journal of neuroscience. vol 54. issue 7. 2021-11-01. PMID:34467592. |
additionally, bdnf val/val individuals had more fmri activity in the hippocampus compared with bdnf met carriers during performance on the navigation task. |
2021-11-01 |
2023-08-13 |
human |
| Stephen R Edwards, Nemat Khan, Elizabeth J Coulson, Maree T Smit. Comparative studies of glial fibrillary acidic protein and brain-derived neurotrophic factor expression in two transgenic mouse models of Alzheimer's disease. Clinical and experimental pharmacology & physiology. vol 47. issue 10. 2021-10-29. PMID:32542833. |
we compared the expression of gfap, bdnf, and its precursor probdnf in the dorsal hippocampus of two transgenic ad mouse models. |
2021-10-29 |
2023-08-13 |
mouse |
| Feng Tai, Che Wang, Xin Deng, Ruojin Li, Zimeng Guo, Haiying Quan, Song L. Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice. Brain research bulletin. vol 164. 2021-10-29. PMID:32877716. |
the hippocampal levels of insulin-like growth factor-1 (igf-1) and brain derived neurotrophic factor (bdnf) were further detected using elisa. |
2021-10-29 |
2023-08-13 |
mouse |
| Feng Tai, Che Wang, Xin Deng, Ruojin Li, Zimeng Guo, Haiying Quan, Song L. Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice. Brain research bulletin. vol 164. 2021-10-29. PMID:32877716. |
in addition, 2m-sd exposure increased ne and da, decreased 5-ht and gaba, and reduced igf-1 and bdnf levels in mouse hippocampus. |
2021-10-29 |
2023-08-13 |
mouse |
| Wellington de Almeida, Heloísa Deola Confortim, Bruna Ferrary Deniz, Patrícia Maidana Miguel, Milene Cardoso Vieira, Loise Bronauth, Adriana Souza Dos Santos, Karine Bertoldi, Ionara Rodrigues Siqueira, Lenir Orlandi Pereir. Acrobatic exercise recovers object recognition memory impairment in hypoxic-ischemic rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 1. 2021-10-28. PMID:33135304. |
bdnf and synaptophysin neuroplasticity markers indicate plastic alterations in the hippocampus and striatum, with maintenance of synaptophysin despite the reduction of total volume tissue, besides, hippocampal hi-induced ipsilateral bdnf increased, and striatum contralateral bdnf decreased were noted. |
2021-10-28 |
2023-08-13 |
rat |
| Janine Karina Hideko Alfenas Horita, Maria Carolina Machado da Silva, Carolina Zaniboni Ferrari, Erica Leandro Marciano Vieira, Fabricio A Moreira, Antônio Carlos Pinheiro de Oliveira, Helton José Rei. Evaluation of Brain Cytokines and the Level of Brain-Derived Neurotrophic Factor in an Inflammatory Model of Depression. Neuroimmunomodulation. vol 27. issue 2. 2021-10-28. PMID:33176302. |
inflammatory processes are likely involved in its pathophysiology, but the underlying mechanisms have remained uncertain.here, we used the model of systemic lipopolysaccharide (lps) injection to test the hypothesis that depressive-like behaviors occur along with changes in the levels of cytokines and brain-derived neurotrophic factor (bdnf) in the hippocampus (hc), prefrontal cortex (pfc), and hypothalamus (ht), and can be prevented by dexamethasone administration. |
2021-10-28 |
2023-08-13 |
Not clear |
| Markus Petermann, Golo Kronenberg, Valentina Mosienko, Michael Bader, Natalia Alenina, Rainer Hellweg, Friederike Klempi. Alterations in BDNF Protein Concentrations in the Hippocampus do not Explain the Pro-Neurogenic Effect of Citalopram on Adult Neurogenesis. Pharmacopsychiatry. vol 54. issue 3. 2021-10-28. PMID:33197939. |
alterations in bdnf protein concentrations in the hippocampus do not explain the pro-neurogenic effect of citalopram on adult neurogenesis. |
2021-10-28 |
2023-08-13 |
Not clear |
| Björn H Schott, Golo Kronenberg, Ulrike Schmidt, Henning P Düsedau, Stefanie Ehrentraut, Olga Geisel, Oliver von Bohlen Und Halbach, Peter Gass, Ildiko Rita Dunay, Rainer Hellwe. Robustly High Hippocampal BDNF levels under Acute Stress in Mice Lacking the Full-length p75 Neurotrophin Receptor. Pharmacopsychiatry. vol 54. issue 5. 2021-10-28. PMID:33592642. |
robustly high hippocampal bdnf levels under acute stress in mice lacking the full-length p75 neurotrophin receptor. |
2021-10-28 |
2023-08-13 |
mouse |
| Björn H Schott, Golo Kronenberg, Ulrike Schmidt, Henning P Düsedau, Stefanie Ehrentraut, Olga Geisel, Oliver von Bohlen Und Halbach, Peter Gass, Ildiko Rita Dunay, Rainer Hellwe. Robustly High Hippocampal BDNF levels under Acute Stress in Mice Lacking the Full-length p75 Neurotrophin Receptor. Pharmacopsychiatry. vol 54. issue 5. 2021-10-28. PMID:33592642. |
acute and chronic stress have been associated with suppression of hippocampal bdnf expression and impaired hippocampal plasticity. |
2021-10-28 |
2023-08-13 |
mouse |
| Björn H Schott, Golo Kronenberg, Ulrike Schmidt, Henning P Düsedau, Stefanie Ehrentraut, Olga Geisel, Oliver von Bohlen Und Halbach, Peter Gass, Ildiko Rita Dunay, Rainer Hellwe. Robustly High Hippocampal BDNF levels under Acute Stress in Mice Lacking the Full-length p75 Neurotrophin Receptor. Pharmacopsychiatry. vol 54. issue 5. 2021-10-28. PMID:33592642. |
we hypothesized that p75ntr might be involved in the hippocampal stress response, in particular in stress-induced bdnf suppression, which might be accompanied by increased neuroinflammation. |
2021-10-28 |
2023-08-13 |
mouse |
| Chao Lu, Xiangfei Liu, Jia Li, Yunke Huang, Xi Huang, Guoliang Dai, Lei W. Merazin Hydrate Produces Rapid Antidepressant Effects Depending on Activating mTOR Signaling by Upregulating Downstream Synaptic Proteins in the Hippocampus. ACS chemical neuroscience. vol 12. issue 20. 2021-10-28. PMID:34601865. |
moreover, the phosphorylated expression of mtor, reduced by lh or cms, was upregulated after a single administration of mh, and the expressions of bdnf and synaptic proteins in the hippocampus were also reversed 2 h later, similar to ketamine. |
2021-10-28 |
2023-08-13 |
Not clear |
| Haoran Sun, Xianqiang Zhang, Yujia Kong, Luping Gou, Bo Lian, Yanyu Wang, Li Jiang, Qi Li, Hongwei Sun, Lin Su. Maternal Separation-Induced Histone Acetylation Correlates with BDNF-Programmed Synaptic Changes in an Animal Model of PTSD with Sex Differences. Molecular neurobiology. vol 58. issue 4. 2021-10-27. PMID:33245480. |
in this study, the extent of histone acetylation in the hippocampus (hip) and the expression of bdnf were measured to determine whether bdnf influences risk of ptsd following ms in early life. |
2021-10-27 |
2023-08-13 |
rat |
| L M C Puhlmann, R Linz, S L Valk, P Vrticka, R Vos de Wael, A Bernasconi, N Bernasconi, B Caldairou, I Papassotiriou, G P Chrousos, B C Bernhardt, T Singer, V Enger. Association between hippocampal structure and serum Brain-Derived Neurotrophic Factor (BDNF) in healthy adults: A registered report. NeuroImage. vol 236. 2021-10-27. PMID:33852941. |
association between hippocampal structure and serum brain-derived neurotrophic factor (bdnf) in healthy adults: a registered report. |
2021-10-27 |
2023-08-13 |
human |
| L M C Puhlmann, R Linz, S L Valk, P Vrticka, R Vos de Wael, A Bernasconi, N Bernasconi, B Caldairou, I Papassotiriou, G P Chrousos, B C Bernhardt, T Singer, V Enger. Association between hippocampal structure and serum Brain-Derived Neurotrophic Factor (BDNF) in healthy adults: A registered report. NeuroImage. vol 236. 2021-10-27. PMID:33852941. |
a growing body of research suggests that hippocampal plasticity is closely linked to the actions of brain-derived neurotrophic factor (bdnf). |
2021-10-27 |
2023-08-13 |
human |
| L M C Puhlmann, R Linz, S L Valk, P Vrticka, R Vos de Wael, A Bernasconi, N Bernasconi, B Caldairou, I Papassotiriou, G P Chrousos, B C Bernhardt, T Singer, V Enger. Association between hippocampal structure and serum Brain-Derived Neurotrophic Factor (BDNF) in healthy adults: A registered report. NeuroImage. vol 236. 2021-10-27. PMID:33852941. |
however, evidence on the relationship between hippocampal volume (hcv) and peripheral bdnf levels is scarce and limited to elderly and patient populations. |
2021-10-27 |
2023-08-13 |
human |
| L M C Puhlmann, R Linz, S L Valk, P Vrticka, R Vos de Wael, A Bernasconi, N Bernasconi, B Caldairou, I Papassotiriou, G P Chrousos, B C Bernhardt, T Singer, V Enger. Association between hippocampal structure and serum Brain-Derived Neurotrophic Factor (BDNF) in healthy adults: A registered report. NeuroImage. vol 236. 2021-10-27. PMID:33852941. |
further, despite evidence that bdnf expression differs throughout the hippocampus and is implicated in adult neurogenesis specifically in the dentate gyrus, no study has so far related peripheral bdnf levels to the volumes of individual hippocampal subfields. |
2021-10-27 |
2023-08-13 |
human |
| Anna Skupien-Jaroszek, Agnieszka Walczak, Iwona Czaban, Katarzyna Karolina Pels, Andrzej Antoni Szczepankiewicz, Katarzyna Krawczyk, Błażej Ruszczycki, Grzegorz Marek Wilczynski, Joanna Dzwonek, Adriana Magalsk. The interplay of seizures-induced axonal sprouting and transcription-dependent Bdnf repositioning in the model of temporal lobe epilepsy. PloS one. vol 16. issue 6. 2021-10-27. PMID:34086671. |
moreover, using in vitro hippocampal cultures we showed that bdnf repositioning is a consequence of transcriptional activity. |
2021-10-27 |
2023-08-13 |
rat |
| Saeed Naghibi, Mohammad Shariatzadeh Joneydi, Ali Barzegari, Azam Davoodabadi, Amirhossein Ebrahimi, Elham Eghdami, Narges Fahimpour, Mahmood Ghorbani, Ehsan Mohammadikia, Mozhgan Rostami, Ali-Akbar Salar. Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with sporadic Alzheimer-like disease. Physiology & behavior. vol 241. 2021-10-27. PMID:34536437. |
treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and bdnf in the hippocampus and prefrontal cortex of rats with sporadic alzheimer-like disease. |
2021-10-27 |
2023-08-13 |
rat |
| Saeed Naghibi, Mohammad Shariatzadeh Joneydi, Ali Barzegari, Azam Davoodabadi, Amirhossein Ebrahimi, Elham Eghdami, Narges Fahimpour, Mahmood Ghorbani, Ehsan Mohammadikia, Mozhgan Rostami, Ali-Akbar Salar. Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with sporadic Alzheimer-like disease. Physiology & behavior. vol 241. 2021-10-27. PMID:34536437. |
we measured brain-derived-neurotrophic factor (bdnf), tumour-necrosis factor (tnf)-α, and interleukin (il)-10 levels in the hippocampus and prefrontal cortex of animals. |
2021-10-27 |
2023-08-13 |
rat |