| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohadeseh Chahkandi, Gholamreza Sepehri, Gholamreza Komeili, Mohammad Khaksari Hadad, Elham Haghparast, Majid Chahkand. The different role of G-protein-coupled receptor 30 (GPR30) in the interaction effects of marijuana and estradiol on spatial learning and memory at different ages. Brain research bulletin. vol 178. 2021-12-09. PMID:34800583. |
furthermore, this study showed that hippocampal bdnf does not have any role in the interaction effects of m and e2 on spatial learning and memory in young and old rats. |
2021-12-09 |
2023-08-13 |
rat |
| Zhang Bao, Yin Jin. Brominated flame retardant TBPH induced oxidative damage and reduced the expression of memory-related proteins in mice, with no discernable impairment of learning and memory. Human & experimental toxicology. vol 40. issue 12_suppl. 2021-12-08. PMID:34784780. |
tbph could significantly decrease the levels of bdnf, p-creb, and psd-95 in the hippocampus, and these tbph-induced neurotoxic effects were attenuated by cur. |
2021-12-08 |
2023-08-13 |
mouse |
| Wei Guan, Da-Wei Xu, Chun-Hui Ji, Cheng-Niu Wang, Yue Liu, Wen-Qian Tang, Jiang-Hong Gu, Yan-Mei Chen, Jie Huang, Jian-Feng Liu, Bo Jian. Hippocampal miR-206-3p participates in the pathogenesis of depression via regulating the expression of BDNF. Pharmacological research. vol 174. 2021-12-07. PMID:34628001. |
hippocampal mir-206-3p participates in the pathogenesis of depression via regulating the expression of bdnf. |
2021-12-07 |
2023-08-13 |
mouse |
| Wei Guan, Da-Wei Xu, Chun-Hui Ji, Cheng-Niu Wang, Yue Liu, Wen-Qian Tang, Jiang-Hong Gu, Yan-Mei Chen, Jie Huang, Jian-Feng Liu, Bo Jian. Hippocampal miR-206-3p participates in the pathogenesis of depression via regulating the expression of BDNF. Pharmacological research. vol 174. 2021-12-07. PMID:34628001. |
both genetic overexpression of hippocampal mir-206-3p and intranasal administration of agomir-206-3p induced not only notable depressive-like behaviors but also significantly decreased hippocampal bdnf signaling cascade and neurogenesis in naïve c57bl/6j mice. |
2021-12-07 |
2023-08-13 |
mouse |
| Wei Guan, Da-Wei Xu, Chun-Hui Ji, Cheng-Niu Wang, Yue Liu, Wen-Qian Tang, Jiang-Hong Gu, Yan-Mei Chen, Jie Huang, Jian-Feng Liu, Bo Jian. Hippocampal miR-206-3p participates in the pathogenesis of depression via regulating the expression of BDNF. Pharmacological research. vol 174. 2021-12-07. PMID:34628001. |
taken together, hippocampal mir-206-3p participates in the pathogenesis of depression by regulating bdnf biosynthesis and is a feasible antidepressant target. |
2021-12-07 |
2023-08-13 |
mouse |
| Vandreza Cardoso Bortolotto, Stífani Machado Araujo, Franciane Cabral Pinheiro, Márcia Rósula Poetini, Luana Barreto Meichtry, Mariana G Fronza, Silvana Peterini Boeira, Lucielli Savegnago, Marina Prigo. Chrysin restores memory deficit in hypothyroidism mice: Behavioral, neurochemical and computational approaches involving the neurotrophinergic system. Journal of psychiatric research. vol 144. 2021-12-07. PMID:34700210. |
then, the levels of neurotrophins (bdnf and ngf) in the hippocampus and prefrontal cortex were measured and tested the affinity of chrysin with neurotrophinergic receptors through molecular docking. |
2021-12-07 |
2023-08-13 |
mouse |
| Vandreza Cardoso Bortolotto, Stífani Machado Araujo, Franciane Cabral Pinheiro, Márcia Rósula Poetini, Luana Barreto Meichtry, Mariana G Fronza, Silvana Peterini Boeira, Lucielli Savegnago, Marina Prigo. Chrysin restores memory deficit in hypothyroidism mice: Behavioral, neurochemical and computational approaches involving the neurotrophinergic system. Journal of psychiatric research. vol 144. 2021-12-07. PMID:34700210. |
hypothyroid mice showed memory deficit in the mwm and reduced neurotrophins levels in the hippocampus and prefrontal cortex, meanwhile, the chrysin treatment was able to reversed the deficit of spatial memory function and increased the levels of bdnf in hipocamppus and ngf in both structures. |
2021-12-07 |
2023-08-13 |
mouse |
| Lingling Zhu, Yanxiu Wang, Xiaowen Lin, Xu Zhao, Zhi Jian F. Effects of Ozone on Hippocampus BDNF and Fos Expressions in Rats with Chronic Compression of Dorsal Root Ganglia. BioMed research international. vol 2021. 2021-12-07. PMID:34869766. |
effects of ozone on hippocampus bdnf and fos expressions in rats with chronic compression of dorsal root ganglia. |
2021-12-07 |
2023-08-13 |
rat |
| Lingling Zhu, Yanxiu Wang, Xiaowen Lin, Xu Zhao, Zhi Jian F. Effects of Ozone on Hippocampus BDNF and Fos Expressions in Rats with Chronic Compression of Dorsal Root Ganglia. BioMed research international. vol 2021. 2021-12-07. PMID:34869766. |
the effects of ozone on hippocampal expression levels of brain-derived neurotrophic factor (bdnf) and c-fos protein (fos) were evaluated in rats with chronic compression of dorsal root ganglia (ccd). |
2021-12-07 |
2023-08-13 |
rat |
| Ying Yu, Zhaokun Shi, Dan Xu, Ying Li, Jun Qin, Zhaohui Zhang, Hui Wan. Prenatal ethanol exposure increases susceptibility to depression- and anxiety-like behavior in adult female offspring and its underlying mechanism. Reproductive toxicology (Elmsford, N.Y.). vol 96. 2021-12-06. PMID:32497709. |
the latter inhibits the hippocampal bdnf pathway, leading to the disruption of hippocampal neurogenesis, apoptosis and decreased synaptic plasticity. |
2021-12-06 |
2023-08-13 |
rat |
| Cassiano Ricardo Alves Faria Diniz, Leandro Antero da Silva, Luana Barreto Domingos, Andreza Buzolin Sonego, Leonardo Resstel Barbosa Moraes, Sâmia Joc. Fluoxetine acts concomitantly on dorsal and ventral hippocampus to Trk-dependently modulate the extinction of fear memory. Progress in neuro-psychopharmacology & biological psychiatry. vol 113. 2021-12-06. PMID:34619303. |
since fluoxetine (flx) effect on extinction of aversive memory is well known to depend on hippocampal bdnf levels, we hypothesized that the hippocampal subregions might play different roles in fluoxetine efficacy in decreasing fear response. |
2021-12-06 |
2023-08-13 |
Not clear |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.). vol 150. issue Pt B. 2021-12-05. PMID:34863499. |
in addition, semen sojae praeparatum significantly promoted the contents of norepinephrine (ne), 5-hydroxytryptamine (5-ht), brain-derived neurotrophic factor (bdnf), and gamma-aminobutyric acid (gaba) in the hippocampus and the content of bdnf in the serum (p < 0.05). |
2021-12-05 |
2023-08-13 |
rat |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.). vol 150. issue Pt B. 2021-12-05. PMID:34863499. |
genus ruminococcaceae_ucg-008 was positively correlated with gaba and bdnf levels in the hippocampus; genus lactobacillus had a positive correlation with 5-ht; and genus bacteroides had negative correlations with 5-ht, bdnf, and ne. |
2021-12-05 |
2023-08-13 |
rat |
| Jung-Eun Lee, So-Young Park, Pyung-Lim Ha. Aging-Dependent Downregulation of SUV39H1 Histone Methyltransferase Increases Susceptibility to Stress-Induced Depressive Behavior. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34536198. |
the sirna-mediated knockdown of suv39h1 increases mkp-1 expression and suppresses p-creb and bdnf expression in ht22 cells and in the hippocampus of mice. |
2021-12-03 |
2023-08-13 |
mouse |
| Jung-Eun Lee, So-Young Park, Pyung-Lim Ha. Aging-Dependent Downregulation of SUV39H1 Histone Methyltransferase Increases Susceptibility to Stress-Induced Depressive Behavior. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34536198. |
rosmarinic acid, a phenolic compound that increases suv39h1 expression, reverses stress-induced changes of suv39h1, mkp-1, and bdnf expression in the hippocampus via an overlapping but distinct mechanism from those of fluoxetine and imipramine and produces anti-depressive effects. |
2021-12-03 |
2023-08-13 |
mouse |
| Rahebeh Mahdinia, Iran Goudarzi, Taghi Lashkarbolouki, Mahmoud Elahdadi Salman. Maternal ethanol exposure induces behavioral deficits through oxidative stress and brain-derived neurotrophic factor interrelation in rat offspring. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 8. 2021-12-02. PMID:34427953. |
total bdnf, bdnf mrna, and creb expression significantly reduced in the hippocampus by ethanol exposure. |
2021-12-02 |
2023-08-13 |
rat |
| Abdullah Al Mamun, Kentaro Matsuzaki, Rafiad Islam, Shahdat Hossain, Md Emon Hossain, Masanori Katakura, Hiroyuki Arai, Osamu Shido, Michio Hashimot. Chronic Administration of Thymoquinone Enhances Adult Hippocampal Neurogenesis and Improves Memory in Rats Via Regulating the BDNF Signaling Pathway. Neurochemical research. 2021-12-02. PMID:34855048. |
chronic administration of thymoquinone enhances adult hippocampal neurogenesis and improves memory in rats via regulating the bdnf signaling pathway. |
2021-12-02 |
2023-08-13 |
rat |
| Abdullah Al Mamun, Kentaro Matsuzaki, Rafiad Islam, Shahdat Hossain, Md Emon Hossain, Masanori Katakura, Hiroyuki Arai, Osamu Shido, Michio Hashimot. Chronic Administration of Thymoquinone Enhances Adult Hippocampal Neurogenesis and Improves Memory in Rats Via Regulating the BDNF Signaling Pathway. Neurochemical research. 2021-12-02. PMID:34855048. |
tq-administered rats showed a profound beneficial effect on avoidance-related learning ability, associated with an increase in the hippocampal mrna and protein levels of brain-derived neurotrophic factor (bdnf), as measured by both real-time pcr and elisa. |
2021-12-02 |
2023-08-13 |
rat |
| Muzaffar Abbas, Sami Alzarea, Roger L Papke, Shafiqur Rahma. Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory Pain. CNS & neurological disorders drug targets. vol 20. issue 4. 2021-12-01. PMID:33380307. |
effects of α7 nicotinic acetylcholine receptor positive allosteric modulator on bdnf, nkcc1 and kcc2 expression in the hippocampus following lipopolysaccharide-induced allodynia and hyperalgesia in a mouse model of inflammatory pain. |
2021-12-01 |
2023-08-13 |
mouse |
| Muzaffar Abbas, Sami Alzarea, Roger L Papke, Shafiqur Rahma. Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory Pain. CNS & neurological disorders drug targets. vol 20. issue 4. 2021-12-01. PMID:33380307. |
the effects of 3a,4,5,9b-tetrahydro-4-(1-naphthalenyl)-3h-cyclopentan[c]quinoline-8-sulfonamide (tqs), an α7 nicotinic acetylcholine receptor positive allosteric modulator (nachr pam), on hippocampal bdnf, cation-chloride cotransporters, nkcc1 and kcc2, expression in inflammatory pain are not known. |
2021-12-01 |
2023-08-13 |
mouse |