| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jamshid Faraji, Hamid Lotfi, Alireza Moharrerie, S Yaghoob Jafari, Nasrin Soltanpour, Rosa Tamannaiee, Kameran Marjani, Shabnam Roudaki, Farhad Naseri, Reza Moeeini, Gerlinde A S Met. Regional Differences in BDNF Expression and Behavior as a Function of Sex and Enrichment Type: Oxytocin Matters. Cerebral cortex (New York, N.Y. : 1991). 2022-01-21. PMID:35059698. |
physical enrichment promoted motor and cognitive functions and hippocampal bdnf mrna and protein expression in both sexes. |
2022-01-21 |
2023-08-13 |
rat |
| Jamshid Faraji, Hamid Lotfi, Alireza Moharrerie, S Yaghoob Jafari, Nasrin Soltanpour, Rosa Tamannaiee, Kameran Marjani, Shabnam Roudaki, Farhad Naseri, Reza Moeeini, Gerlinde A S Met. Regional Differences in BDNF Expression and Behavior as a Function of Sex and Enrichment Type: Oxytocin Matters. Cerebral cortex (New York, N.Y. : 1991). 2022-01-21. PMID:35059698. |
these changes were accompanied by elevated plasma oxytocin (ot) levels and bdnf mrna expression in the mpfc, while the hippocampus was not affected. |
2022-01-21 |
2023-08-13 |
rat |
| b' Alba Toll, Laura Blanco-Hinojo, Daniel Berg\\xc3\\xa9, Xavier Duran, Irene Canosa, Teresa Legido, Federico Marmol, V\\xc3\\xadctor P\\xc3\\xa9rez-Sol\\xc3\\xa0, Emilio Fern\\xc3\\xa1ndez-Egea, Anna Man\\xc3\\xa. Multidimensional predictors of negative symptoms in antipsychotic-naive first-episode psychosis. Journal of psychiatry & neuroscience : JPN. vol 47. issue 1. 2022-01-20. PMID:35046133.' |
the present study aimed to identify baseline clinical or neurobiological factors - including peripheral brain-derived neurotrophic factor (bdnf) levels and amygdala or hippocampal relative volumes - that could predict negative symptomatology and persistent negative symptoms in first-episode psychosis after 1 year of follow-up. |
2022-01-20 |
2023-08-13 |
Not clear |
| Chunping Yin, Qi Zhang, Juan Zhao, Yanan Li, Jiaxu Yu, Wei Li, Qiujun Wan. Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats. Neurochemical research. 2022-01-18. PMID:35040026. |
furthermore, nec-1 remarkably increased bdnf and p-trkb/trkb expression in the hippocampus of aged rats. |
2022-01-18 |
2023-08-13 |
rat |
| Marina F Souza, Katty A A L Medeiros, Lívia C R F Lins, José M M Bispo, Auderlan M Gois, Edson R Santos, Thiago H Almeida-Souza, João E C Melo, Heitor S Franco, Rodolfo S Silva, Eduardo A Pereira-Filho, Marco Aurelio M Freire, José R Santo. Motor, memory, and anxiety-like behavioral impairments associated with brain-derived neurotrophic factor and dopaminergic imbalance after inhalational exposure to deltamethrin. Brain research bulletin. 2022-01-18. PMID:35041849. |
the animals submitted to 9 inhalations of dm showed a reduction in immunoreactivity for th in the substantia nigra pars compacta (snpc), ventral tegmental area (vta), and dorsal striatum (ds) areas, and an increase in bdnf in the ds and ca1, ca3 and dentate gyrus (dg) hippocampal areas. |
2022-01-18 |
2023-08-13 |
rat |
| Marina F Souza, Katty A A L Medeiros, Lívia C R F Lins, José M M Bispo, Auderlan M Gois, Edson R Santos, Thiago H Almeida-Souza, João E C Melo, Heitor S Franco, Rodolfo S Silva, Eduardo A Pereira-Filho, Marco Aurelio M Freire, José R Santo. Motor, memory, and anxiety-like behavioral impairments associated with brain-derived neurotrophic factor and dopaminergic imbalance after inhalational exposure to deltamethrin. Brain research bulletin. 2022-01-18. PMID:35041849. |
conversely, the animals submitted to 15 inhalations of dm showed immunoreactivity reduced for th in the snpc and vta, and an increase in bdnf in the hippocampal areas (ca3 and dg). |
2022-01-18 |
2023-08-13 |
rat |
| Annabel K Short, Viet Bui, Isabel C Zbukvic, Anthony J Hannan, Terence Y Pang, Jee Hyun Ki. Sex-dependent effects of chronic exercise on cognitive flexibility but not hippocampal Bdnf in aging mice. Neuronal signaling. vol 6. issue 1. 2022-01-17. PMID:35036000. |
sex-dependent effects of chronic exercise on cognitive flexibility but not hippocampal bdnf in aging mice. |
2022-01-17 |
2023-08-13 |
mouse |
| Juan Wang, Feng Gao, Shuai Cui, Shaojie Yang, Fang Gao, Xuncui Wang, Guoqi Zh. Utility of 7,8-dihydroxyflavone in preventing astrocytic and synaptic deficits in the hippocampus elicited by PTSD. Pharmacological research. 2022-01-13. PMID:35026406. |
from the perspective of synaptic function, the sps&s model displayed reduced expression of bdnf, p-trkb, postsynaptic density protein 95 (psd95), ampa receptor subunit glur1 (glua1), nmda receptor subunit n2a/n2b ratio, calpain-1, phosphorylated protein kinase b (akt) and phosphorylated mammalian target of rapamycin (mtor) and conversely, higher phosphatase and tension homolog (pten) expression in the hippocampus. |
2022-01-13 |
2023-08-13 |
mouse |
| Alessandro Virtuoso, Pernille Tveden-Nyborg, Anne Marie Voigt Schou-Pedersen, Jens Lykkesfeldt, Heidi Kaastrup Müller, Betina Elfving, Dorte Bratbo Sørense. A Long-Term Energy-Rich Diet Increases Prefrontal BDNF in Sprague-Dawley Rats. Nutrients. vol 14. issue 1. 2022-01-11. PMID:35011001. |
findings of the effect of high-fat feeding including "cafeteria diets" (caf) on brain-derived neurotrophic factor (bdnf) in the hippocampus (hip) and prefrontal cortex (pfc) in rodents are conflicting. |
2022-01-11 |
2023-08-13 |
human |
| Kensuke Nakajima, Shinya Okubo, Shigeru Ois. Identification of traditional Japanese Kampo medicines and crude drugs that upregulate brain‑derived neurotrophic factor in human peripheral cells. Acta neurobiologiae experimentalis. vol 81. issue 4. 2022-01-11. PMID:35014988. |
the neurotrophic hypothesis of depression, which suggests that decreased hippocampal brain‑derived neurotrophic factor (bdnf) levels cause depression, has become increasingly popular. |
2022-01-11 |
2023-08-13 |
human |
| Guo-Liang Dai, Xin-Yi Yang, Shan-Shan Chen, Yi-Qing Wang, Mei-Chen Liu, Yang Cao, Fei-Ran Li, Cheng-Yao Ma, Wen-Zheng J. [Effects of Jiaotai Pills on CUMS-induced depression model in mice based on changes of SIRT1 expression in hippocampus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994144. |
enzyme-linked immunosorbent assay(elisa) kits were used to detect the levels of interleukin(il)-1β, il-6, tumor necrosis factor-α(tnf-α), and brain-derived neurotrophic factor(bdnf) in the hippocampus and serum of mice. |
2022-01-07 |
2023-08-13 |
mouse |
| Guo-Liang Dai, Xin-Yi Yang, Shan-Shan Chen, Yi-Qing Wang, Mei-Chen Liu, Yang Cao, Fei-Ran Li, Cheng-Yao Ma, Wen-Zheng J. [Effects of Jiaotai Pills on CUMS-induced depression model in mice based on changes of SIRT1 expression in hippocampus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994144. |
in the hippocampus and serum, the levels of il-1β, il-6, tnf-α, and mda were increased(p<0.01), and the activity of sod and the levels of gsh, da, 5-ht, ne, and bdnf were reduced(p<0.01). |
2022-01-07 |
2023-08-13 |
mouse |
| Guo-Liang Dai, Xin-Yi Yang, Shan-Shan Chen, Yi-Qing Wang, Mei-Chen Liu, Yang Cao, Fei-Ran Li, Cheng-Yao Ma, Wen-Zheng J. [Effects of Jiaotai Pills on CUMS-induced depression model in mice based on changes of SIRT1 expression in hippocampus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994144. |
the treatment with high-dose jiaotai pills increased the sucrose preference rate, movement distance, and the number of crossing centers(p<0.05), reduced tail suspension time and swimming immobility time(p<0.01), elevated hippocampal sirt1 expression level(p<0.01), decreased hippocampal and serum il-1β, il-6, tnf-α, and mda levels(p<0.01), potentiated sod activity, and up-regulated gsh, da, 5-ht, ne, and bdnf levels in the hippocampus and serum(p<0.05, p<0.01) in model mice. |
2022-01-07 |
2023-08-13 |
mouse |
| Yuan Zhou, Shao-Fu Li, Li-Sha Deng, Yong-Kang Ma, Gang Lei, Yong-Hui Dan. HINT1 deficiency in aged mice reduces anxiety-like and depression-like behaviours and enhances cognitive performances. Experimental gerontology. 2022-01-07. PMID:34995725. |
in addition, hint1 ko mice also showed increased gsh-px and superoxide dismutase, and decreased malondialdehyde, together with enhanced bdnf and trk-b expression in the hippocampus and pfc. |
2022-01-07 |
2023-08-13 |
mouse |
| Rosmara Infantino, Concetta Schiano, Livio Luongo, Salvatore Paino, Gelsomina Mansueto, Serena Boccella, Francesca Guida, Flavia Ricciardi, Monica Iannotta, Carmela Belardo, Ida Marabese, Gorizio Pieretti, Nicola Serra, Claudio Napoli, Sabatino Maion. MED1/BDNF/TrkB pathway is involved in thalamic hemorrhage-induced pain and depression by regulating microglia. Neurobiology of disease. 2022-01-07. PMID:34995755. |
hippocampal med1 and trkb expressions were significantly increased in th compared to sham mice 21 days post-th, whereas bdnf levels were decreased. |
2022-01-07 |
2023-08-13 |
mouse |
| N A Alfaris, G M Alshammari, J Z Altamimi, D H Aljabryn, R I Alagal, H Aldera, M A Alkhateeb, M A Yahy. Ellagic acid prevents streptozotocin-induced hippocampal damage and memory loss in rats by stimulating Nrf2 and nuclear factor-κB, and activating insulin receptor substrate/PI3K/Akt axis. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 72. issue 4. 2022-01-06. PMID:34987124. |
besides, and in the hippocampus of both groups, ea increased the phosphorylation of insulin receptor substrate (irs), pi3k, akt, gs3kβ, and creb, and increased levels of bdnf and bcl-2. |
2022-01-06 |
2023-08-13 |
rat |
| Roya Malekloo, Setayesh Nematollahi, Abbas Ali Vafei, Ali Rashidy-Pou. Effects of different intensities of treadmill exercise on cued fear extinction failure, hippocampal BDNF decline, and Bax/Bcl-2 ratio alteration in chronic - morphine treated male rats. Behavioural brain research. 2022-01-06. PMID:34990697. |
effects of different intensities of treadmill exercise on cued fear extinction failure, hippocampal bdnf decline, and bax/bcl-2 ratio alteration in chronic - morphine treated male rats. |
2022-01-06 |
2023-08-13 |
rat |
| Roya Malekloo, Setayesh Nematollahi, Abbas Ali Vafei, Ali Rashidy-Pou. Effects of different intensities of treadmill exercise on cued fear extinction failure, hippocampal BDNF decline, and Bax/Bcl-2 ratio alteration in chronic - morphine treated male rats. Behavioural brain research. 2022-01-06. PMID:34990697. |
this work investigated the effects of forced exercise with different intensities on cued fear extinction impairment and alternations of hippocampal bdnf and apoptotic proteins induced by chronic morphine. |
2022-01-06 |
2023-08-13 |
rat |
| Roya Malekloo, Setayesh Nematollahi, Abbas Ali Vafei, Ali Rashidy-Pou. Effects of different intensities of treadmill exercise on cued fear extinction failure, hippocampal BDNF decline, and Bax/Bcl-2 ratio alteration in chronic - morphine treated male rats. Behavioural brain research. 2022-01-06. PMID:34990697. |
subsequently, rats received a cued fear conditioning followed by four days of extinction training, and the expression of hippocampal bdnf and apoptotic proteins was determined. |
2022-01-06 |
2023-08-13 |
rat |
| Roya Malekloo, Setayesh Nematollahi, Abbas Ali Vafei, Ali Rashidy-Pou. Effects of different intensities of treadmill exercise on cued fear extinction failure, hippocampal BDNF decline, and Bax/Bcl-2 ratio alteration in chronic - morphine treated male rats. Behavioural brain research. 2022-01-06. PMID:34990697. |
a relatively long time after the last injection of morphine (35 days), rats again showed cued fear extinction failure and reduced hippocampal bdnf, which recovered by light and moderate, but not high exercise. |
2022-01-06 |
2023-08-13 |
rat |