| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Yu, Zhaokun Shi, Dan Xu, Ying Li, Jun Qin, Zhaohui Zhang, Hui Wan. Prenatal ethanol exposure increases susceptibility to depression- and anxiety-like behavior in adult female offspring and its underlying mechanism. Reproductive toxicology (Elmsford, N.Y.). vol 96. 2021-12-06. PMID:32497709. |
the latter inhibits the hippocampal bdnf pathway, leading to the disruption of hippocampal neurogenesis, apoptosis and decreased synaptic plasticity. |
2021-12-06 |
2023-08-13 |
rat |
| Cassiano Ricardo Alves Faria Diniz, Leandro Antero da Silva, Luana Barreto Domingos, Andreza Buzolin Sonego, Leonardo Resstel Barbosa Moraes, Sâmia Joc. Fluoxetine acts concomitantly on dorsal and ventral hippocampus to Trk-dependently modulate the extinction of fear memory. Progress in neuro-psychopharmacology & biological psychiatry. vol 113. 2021-12-06. PMID:34619303. |
since fluoxetine (flx) effect on extinction of aversive memory is well known to depend on hippocampal bdnf levels, we hypothesized that the hippocampal subregions might play different roles in fluoxetine efficacy in decreasing fear response. |
2021-12-06 |
2023-08-13 |
Not clear |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.). vol 150. issue Pt B. 2021-12-05. PMID:34863499. |
in addition, semen sojae praeparatum significantly promoted the contents of norepinephrine (ne), 5-hydroxytryptamine (5-ht), brain-derived neurotrophic factor (bdnf), and gamma-aminobutyric acid (gaba) in the hippocampus and the content of bdnf in the serum (p < 0.05). |
2021-12-05 |
2023-08-13 |
rat |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.). vol 150. issue Pt B. 2021-12-05. PMID:34863499. |
genus ruminococcaceae_ucg-008 was positively correlated with gaba and bdnf levels in the hippocampus; genus lactobacillus had a positive correlation with 5-ht; and genus bacteroides had negative correlations with 5-ht, bdnf, and ne. |
2021-12-05 |
2023-08-13 |
rat |
| Jung-Eun Lee, So-Young Park, Pyung-Lim Ha. Aging-Dependent Downregulation of SUV39H1 Histone Methyltransferase Increases Susceptibility to Stress-Induced Depressive Behavior. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34536198. |
the sirna-mediated knockdown of suv39h1 increases mkp-1 expression and suppresses p-creb and bdnf expression in ht22 cells and in the hippocampus of mice. |
2021-12-03 |
2023-08-13 |
mouse |
| Jung-Eun Lee, So-Young Park, Pyung-Lim Ha. Aging-Dependent Downregulation of SUV39H1 Histone Methyltransferase Increases Susceptibility to Stress-Induced Depressive Behavior. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34536198. |
rosmarinic acid, a phenolic compound that increases suv39h1 expression, reverses stress-induced changes of suv39h1, mkp-1, and bdnf expression in the hippocampus via an overlapping but distinct mechanism from those of fluoxetine and imipramine and produces anti-depressive effects. |
2021-12-03 |
2023-08-13 |
mouse |
| Rahebeh Mahdinia, Iran Goudarzi, Taghi Lashkarbolouki, Mahmoud Elahdadi Salman. Maternal ethanol exposure induces behavioral deficits through oxidative stress and brain-derived neurotrophic factor interrelation in rat offspring. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 8. 2021-12-02. PMID:34427953. |
total bdnf, bdnf mrna, and creb expression significantly reduced in the hippocampus by ethanol exposure. |
2021-12-02 |
2023-08-13 |
rat |
| Abdullah Al Mamun, Kentaro Matsuzaki, Rafiad Islam, Shahdat Hossain, Md Emon Hossain, Masanori Katakura, Hiroyuki Arai, Osamu Shido, Michio Hashimot. Chronic Administration of Thymoquinone Enhances Adult Hippocampal Neurogenesis and Improves Memory in Rats Via Regulating the BDNF Signaling Pathway. Neurochemical research. 2021-12-02. PMID:34855048. |
chronic administration of thymoquinone enhances adult hippocampal neurogenesis and improves memory in rats via regulating the bdnf signaling pathway. |
2021-12-02 |
2023-08-13 |
rat |
| Abdullah Al Mamun, Kentaro Matsuzaki, Rafiad Islam, Shahdat Hossain, Md Emon Hossain, Masanori Katakura, Hiroyuki Arai, Osamu Shido, Michio Hashimot. Chronic Administration of Thymoquinone Enhances Adult Hippocampal Neurogenesis and Improves Memory in Rats Via Regulating the BDNF Signaling Pathway. Neurochemical research. 2021-12-02. PMID:34855048. |
tq-administered rats showed a profound beneficial effect on avoidance-related learning ability, associated with an increase in the hippocampal mrna and protein levels of brain-derived neurotrophic factor (bdnf), as measured by both real-time pcr and elisa. |
2021-12-02 |
2023-08-13 |
rat |
| Muzaffar Abbas, Sami Alzarea, Roger L Papke, Shafiqur Rahma. Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory Pain. CNS & neurological disorders drug targets. vol 20. issue 4. 2021-12-01. PMID:33380307. |
effects of α7 nicotinic acetylcholine receptor positive allosteric modulator on bdnf, nkcc1 and kcc2 expression in the hippocampus following lipopolysaccharide-induced allodynia and hyperalgesia in a mouse model of inflammatory pain. |
2021-12-01 |
2023-08-13 |
mouse |
| Muzaffar Abbas, Sami Alzarea, Roger L Papke, Shafiqur Rahma. Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory Pain. CNS & neurological disorders drug targets. vol 20. issue 4. 2021-12-01. PMID:33380307. |
the effects of 3a,4,5,9b-tetrahydro-4-(1-naphthalenyl)-3h-cyclopentan[c]quinoline-8-sulfonamide (tqs), an α7 nicotinic acetylcholine receptor positive allosteric modulator (nachr pam), on hippocampal bdnf, cation-chloride cotransporters, nkcc1 and kcc2, expression in inflammatory pain are not known. |
2021-12-01 |
2023-08-13 |
mouse |
| Muzaffar Abbas, Sami Alzarea, Roger L Papke, Shafiqur Rahma. Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory Pain. CNS & neurological disorders drug targets. vol 20. issue 4. 2021-12-01. PMID:33380307. |
the objective of the study was to determine the effects of tqs on bdnf, nkcc1, and kcc2 expression in the hippocampus following lipopolysaccharide (lps)-induced allodynia and hyperalgesia in a mouse model of inflammatory pain. |
2021-12-01 |
2023-08-13 |
mouse |
| Masahiro Okamoto, Daisuke Mizuuchi, Koki Omura, Minchul Lee, Akihiko Oharazawa, Jang Soo Yook, Koshiro Inoue, Hideaki Soy. High-intensity Intermittent Training Enhances Spatial Memory and Hippocampal Neurogenesis Associated with BDNF Signaling in Rats. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 9. 2021-12-01. PMID:33982757. |
high-intensity intermittent training enhances spatial memory and hippocampal neurogenesis associated with bdnf signaling in rats. |
2021-12-01 |
2023-08-13 |
human |
| Masahiro Okamoto, Daisuke Mizuuchi, Koki Omura, Minchul Lee, Akihiko Oharazawa, Jang Soo Yook, Koshiro Inoue, Hideaki Soy. High-intensity Intermittent Training Enhances Spatial Memory and Hippocampal Neurogenesis Associated with BDNF Signaling in Rats. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 9. 2021-12-01. PMID:33982757. |
simultaneously, both hiit and mict led to enhanced spatial memory and adult hippocampal neurogenesis (ahn) as well as enhanced protein levels of hippocampal brain-derived neurotrophic factor (bdnf) signaling. |
2021-12-01 |
2023-08-13 |
human |
| Masahiro Okamoto, Daisuke Mizuuchi, Koki Omura, Minchul Lee, Akihiko Oharazawa, Jang Soo Yook, Koshiro Inoue, Hideaki Soy. High-intensity Intermittent Training Enhances Spatial Memory and Hippocampal Neurogenesis Associated with BDNF Signaling in Rats. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 9. 2021-12-01. PMID:33982757. |
collectively, we suggest that hiit could be a time-efficient exercise protocol that enhances hippocampal memory and neurogenesis in rats and is associated with hippocampal bdnf signaling. |
2021-12-01 |
2023-08-13 |
human |
| Wenya Pei, Fanqi Meng, Qingwen Deng, Baobao Zhang, Yuan Gu, Boyu Jiao, Haoyu Xu, Jiuqing Tan, Xin Zhou, Zhiling Li, Guanheng He, Jingwen Ruan, Ying Din. Electroacupuncture promotes the survival and synaptic plasticity of hippocampal neurons and improvement of sleep deprivation-induced spatial memory impairment. CNS neuroscience & therapeutics. vol 27. issue 12. 2021-12-01. PMID:34623740. |
this study aimed to investigate whether electroacupuncture (ea) promotes the survival and synaptic plasticity of hippocampal neurons by activating brain-derived neurotrophic factor (bdnf)/tyrosine receptor kinase (trkb)/extracellular signal-regulated kinase (erk) signaling, thereby improving spatial memory deficits in rats under sd. |
2021-12-01 |
2023-08-13 |
rat |
| Özlem Saral, Hüseyin Şahin, Sinan Saral, Mehmet Alkanat, Kerimali Akyıldız, Atilla Topçu, Adnan Yılma. Bee pollen increases hippocampal brain-derived neurotrophic factor and suppresses neuroinflammation in adult rats with chronic immobilization stress. Neuroscience letters. vol 766. 2021-12-01. PMID:34774703. |
brain-derived neurotrophic factor (bdnf), interleukin 1 beta (il-1β), and tumor necrosis factor-alpha (tnf-α) levels were measured by elisa to evaluate neurological and biochemical changes in rat hippocampal tissue. |
2021-12-01 |
2023-08-13 |
rat |
| Özlem Saral, Hüseyin Şahin, Sinan Saral, Mehmet Alkanat, Kerimali Akyıldız, Atilla Topçu, Adnan Yılma. Bee pollen increases hippocampal brain-derived neurotrophic factor and suppresses neuroinflammation in adult rats with chronic immobilization stress. Neuroscience letters. vol 766. 2021-12-01. PMID:34774703. |
moreover, bee pollen significantly increased the level of bdnf in the hippocampus. |
2021-12-01 |
2023-08-13 |
rat |
| Reza Yakhkeshi, Fatemeh Roshani, Kobra Akhoundzadeh, Sakineh Shafi. Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD). Physiology & behavior. vol 243. 2021-11-30. PMID:34743976. |
effect of treadmill exercise on serum corticosterone, serum and hippocampal bdnf, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (ptsd). |
2021-11-30 |
2023-08-13 |
rat |
| Reza Yakhkeshi, Fatemeh Roshani, Kobra Akhoundzadeh, Sakineh Shafi. Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD). Physiology & behavior. vol 243. 2021-11-30. PMID:34743976. |
the results showed that ovariectomy worsened the effect of sps on hippocampal bdnf and led to greater increase in serum corticosterone and hippocampal caspase 3 and bax in sps rats. |
2021-11-30 |
2023-08-13 |
rat |