| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Saeid Fakhraei, Mohammad Reza Almasi, Maghsoud Peeri, Reza Gharakhanlo. The effect of 4-Week rehabilitation by aerobic exercise on hippocampus BDNF and TGF-β1 gene expressions inAβ 1-42-induced rat model of Alzheimer's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 95. 2021-12-20. PMID:34929632. |
this study aimed to determine the effect of 4 weeks of aerobic rehabilitation exercise (rhexe) on the genes expression of bdnf and tgf-β1 in the hippocampus tissue of rats with the ad induced by injection of amyloid-beta (aβ |
2021-12-20 |
2023-08-13 |
rat |
| Hiroyuki Umegaki, Takashi Sakurai, Hidenori Ara. Active Life for Brain Health: A Narrative Review of the Mechanism Underlying the Protective Effects of Physical Activity on the Brain. Frontiers in aging neuroscience. vol 13. 2021-12-17. PMID:34916925. |
the most intensively studied mechanisms of the beneficial effects of pa involve an increase in brain-derived neurotrophic factor (bdnf) and preservation of brain volume, especially that of the hippocampus. |
2021-12-17 |
2023-08-13 |
human |
| Ghasem Majdi Yazdi, Gholamhasan Vaezi, Vida Hojati, Mohammad Mohammad-Zade. The Effect of 6-gingerol on Growth Factors and Apoptosis Indices in Rats Exposed to Gold Nanoparticles. Basic and clinical neuroscience. vol 12. issue 3. 2021-12-17. PMID:34917289. |
given the antioxidant properties of gingerol (ging), this study aimed to determine the protective effect of 6-gingerol on hippocampal levels of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), dna oxidative damage, and the amount of bax and bcl2 apoptosis indices of rats exposed to aunps. |
2021-12-17 |
2023-08-13 |
rat |
| Naeemeh Khalesi, Mojgan Bandehpour, Mohammad Reza Bigdeli, Hassan Niknejad, Ali Dabbagh, Bahram Kazem. 14-3-3ζ protein protects against brain ischemia/reperfusion injury and induces BDNF transcription after MCAO in rat. Journal of applied biomedicine. vol 17. issue 2. 2021-12-15. PMID:34907731. |
the present study showed that 14-3-3ζ could up-regulate bdnf mrna at early time point after ischemia in the hippocampus, in the cortex and in the piriform cortex-amygdala and could also improve neurological outcome and reduce infarct volume. |
2021-12-15 |
2023-08-13 |
human |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
these two factors can modify areas related to memory and learning as the hippocampus, through mechanisms related to the gene expression of brain-derived neurotrophic factor (bdnf). |
2021-12-15 |
2023-08-13 |
rat |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
in addition, these changes in early life may affect the functioning of the hippocampus during adulthood through mechanisms mediated by bdnf. |
2021-12-15 |
2023-08-13 |
rat |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
thereby, evidence from the scientific literature suggests that the mechanisms of synaptic plasticity in the hippocampus of adult animals are influenced by malnutrition and ee, and these alterations may involve the participation of bdnf as a key regulator in memory processes in the adult animal hippocampus. |
2021-12-15 |
2023-08-13 |
rat |
| Nader Asadian, Houman Parsaie, Abbas Ali Vafaei, Masoumeh Dadkhah, Samira Omoumi, Katayoun Sedagha. Chronic light deprivation induces different effects on spatial and fear memory and hippocampal BDNF/TRKB expression during light and dark phases of rat diurnal rhythm. Behavioural brain research. vol 418. 2021-12-11. PMID:34695541. |
bdnf and trkb protein levels in the hippocampus of rats from the four sub-groups were measured by western blot, at the completion of the 3 week constant darkness exposure and after the behavioral experiments. |
2021-12-11 |
2023-08-13 |
human |
| Azam Moosavi Sohroforouzani, Saeed Shakerian, Mohsen Ghanbarzadeh, Hojjatallah Alae. Effect of forced treadmill exercise on stimulation of BDNF expression, depression symptoms, tactile memory and working memory in LPS-treated rats. Behavioural brain research. vol 418. 2021-12-11. PMID:34743949. |
this study aimed to investigate the effect of forced treadmill exercise on hippocampal bdnf expression levels, depression symptoms, tactile memory and working memory in lipopolysaccharide (lps)-treated rats. |
2021-12-11 |
2023-08-13 |
rat |
| Azam Moosavi Sohroforouzani, Saeed Shakerian, Mohsen Ghanbarzadeh, Hojjatallah Alae. Effect of forced treadmill exercise on stimulation of BDNF expression, depression symptoms, tactile memory and working memory in LPS-treated rats. Behavioural brain research. vol 418. 2021-12-11. PMID:34743949. |
finally, the hippocampus of rats was removed and used for determination of bdnf expression levels by real-time polymerase chain reaction (real-time pcr). |
2021-12-11 |
2023-08-13 |
rat |
| Adnan M Massadeh, Karem H Alzoubi, Amal M Milhem, Abeer M Rababa'h, Omar F Khabou. Evaluating the effect of selenium on spatial memory impairment induced by sleep deprivation. Physiology & behavior. vol 244. 2021-12-11. PMID:34871651. |
moreover, we measured the levels of reduced glutathione (gsh), oxidized glutathione (gssg) and gsh/gssg, catalase, glutathione peroxidase (gpx), superoxide dismutase (sod), thiobarbituric acid reactive substances (tbars) and brain derived neurotrophic factor (bdnf) in the hippocampus. |
2021-12-11 |
2023-08-13 |
rat |
| Lu-Lu Xue, Ruo-Lan Du, Yue Hu, Liu-Lin Xiong, Zhang-Yu Su, Zheng Ma, Ya-Xin Tan, Jia Liu, Qiao Hu, Zhao-Qiong Zhu, Xue-Zheng Liu, Ting-Hua Wan. BDNF promotes neuronal survival after neonatal hypoxic-ischemic encephalopathy by up-regulating Stx1b and suppressing VDAC1. Brain research bulletin. vol 174. 2021-12-10. PMID:34058286. |
then, protein chip was applied to detect the differential expression genes in cortex and hippocampus and found the brain-derived neurotrophic factor (bdnf) down-regulated both in cortex and hippocampus. |
2021-12-10 |
2023-08-13 |
rat |
| Lu-Lu Xue, Ruo-Lan Du, Yue Hu, Liu-Lin Xiong, Zhang-Yu Su, Zheng Ma, Ya-Xin Tan, Jia Liu, Qiao Hu, Zhao-Qiong Zhu, Xue-Zheng Liu, Ting-Hua Wan. BDNF promotes neuronal survival after neonatal hypoxic-ischemic encephalopathy by up-regulating Stx1b and suppressing VDAC1. Brain research bulletin. vol 174. 2021-12-10. PMID:34058286. |
moreover, low expression of bdnf after hi in right cortex and hippocampus was validate by immunohistochemistry (ihc) and western blotting (wb). |
2021-12-10 |
2023-08-13 |
rat |
| Mengjuan Shang, Jimeng Zhang, Meilun Shen, Zhichuan Sun, Peng Gao, Jing Li, Junlin Xing, Guozhen Gu. Bright light exposure induces dynamic changes of spatial memory in nocturnal rodents. Brain research bulletin. vol 174. 2021-12-10. PMID:34197939. |
moreover, higher expression of brain-derived neurotrophic factor (bdnf) was followed by increased phosphorylated trkb levels in the hippocampus, indicating that bdnf/trkb signaling is also activated during this process. |
2021-12-10 |
2023-08-13 |
mouse |
| Elizabeth Ruiz-Sánchez, Arely M López-Ramírez, Ángel Ruiz-Chow, Minerva Calvillo, Aldo A Reséndiz-Albor, Brenda Anguiano, Patricia Roja. Variability in Behavioral Phenotypes after Forced Swimming-Induced Stress in Rats Is Associated with Expression of the Glucocorticoid Receptor, Nurr1, and IL-1β in the Hippocampus. International journal of molecular sciences. vol 22. issue 23. 2021-12-10. PMID:34884503. |
we assessed whether individual behavioral phenotype to acute stress is related with the hippocampal expression of glucocorticoid receptor (gr), nurr1, interleukin-1 beta (il-1β) or brain-derived neurotrophic factor (bdnf). |
2021-12-10 |
2023-08-13 |
rat |
| Elizabeth Ruiz-Sánchez, Arely M López-Ramírez, Ángel Ruiz-Chow, Minerva Calvillo, Aldo A Reséndiz-Albor, Brenda Anguiano, Patricia Roja. Variability in Behavioral Phenotypes after Forced Swimming-Induced Stress in Rats Is Associated with Expression of the Glucocorticoid Receptor, Nurr1, and IL-1β in the Hippocampus. International journal of molecular sciences. vol 22. issue 23. 2021-12-10. PMID:34884503. |
behavioral response was analyzed, and it was compared with the gene and protein expression of gr, nurr1, il-1β and bdnf in the hippocampus for each time point. |
2021-12-10 |
2023-08-13 |
rat |
| Zuoli Sun, Lina Jia, Dandan Shi, Yi He, Yanping Ren, Jian Yang, Xin M. Deep brain stimulation improved depressive-like behaviors and hippocampal synapse deficits by activating the BDNF/mTOR signaling pathway. Behavioural brain research. 2021-12-10. PMID:34890598. |
furthermore, dbs restored the reduced synaptic density in the hippocampus induced by cus and increased the expression or activity of bdnf, akt, and mtor in the hippocampus. |
2021-12-10 |
2023-08-13 |
rat |
| Amalia Dávila-Hernández, Roberto González-González, Sonia Guzmán-Velázquez, Olivia Tania Hernández Hernández, Sergio R Zamudio, Lucía Martínez-Mot. Antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal BDNF expression in male rats. Brain research bulletin. vol 173. 2021-12-09. PMID:33991609. |
antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal bdnf expression in male rats. |
2021-12-09 |
2023-08-13 |
rat |
| Ehsan Asadi, Fariba Khodagholi, Sareh Asadi, Hamed Mohammadi Kamsorkh, Neda Kaveh, Ali Malek. Quality of early-life maternal care predicts empathy-like behavior in adult male rats: Linking empathy to BDNF gene expression in associated brain regions. Brain research. vol 1767. 2021-12-09. PMID:34192516. |
additionally, gene expression of bdnf was measured in the amygdala, hippocampus, insula, anterior cingulate cortex, prefrontal cortex, and striatum in these adult male rats. |
2021-12-09 |
2023-08-13 |
rat |
| Mohadeseh Chahkandi, Gholamreza Sepehri, Gholamreza Komeili, Mohammad Khaksari Hadad, Elham Haghparast, Majid Chahkand. The different role of G-protein-coupled receptor 30 (GPR30) in the interaction effects of marijuana and estradiol on spatial learning and memory at different ages. Brain research bulletin. vol 178. 2021-12-09. PMID:34800583. |
moreover, hippocampal bdnf level was assessed by the elisa method. |
2021-12-09 |
2023-08-13 |
rat |