| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Paola Tramonti Fantozzi, Giulia Lazzarini, Vincenzo De Cicco, Angela Briganti, Serena Argento, Davide De Cicco, Massimo Barresi, Enrico Cataldo, Luca Bruschini, Paola d'Ascanio, Andrea Pirone, Carla Lenzi, Iacopo Vannozzi, Vincenzo Miragliotta, Ugo Faraguna, Diego Manzon. The path from trigeminal asymmetry to cognitive impairment: a behavioral and molecular study. Scientific reports. vol 11. issue 1. 2021-11-19. PMID:33637775. |
in adult rats, a distal unilateral section of the trigeminal mandibular branch reduced, on the contralateral side, the expression of c-fos (brainstem) and bdnf (brainstem, hippocampus, frontal cortex). |
2021-11-19 |
2023-08-13 |
human |
| Sanjay N Awathale, Akash M Waghade, Harish M Kawade, Gouri Jadhav, Amit G Choudhary, Sneha Sagarkar, Amul J Sakharkar, Nishikant K Subhedar, Dadasaheb M Kokar. Neuroplastic Changes in the Superior Colliculus and Hippocampus in Self-rewarding Paradigm: Importance of Visual Cues. Molecular neurobiology. 2021-11-19. PMID:34797522. |
concomitantly, the hippocampus showed augmented neurogenesis as well as bdnf protein and mrna expression. |
2021-11-19 |
2023-08-13 |
rat |
| Hakimeh Saadati, Farshid Sadegzadeh, Nona Sakhaie, Hamdollah Panahpour, Mohsen Sagh. Serotonin depletion during the postnatal developmental period causes behavioral and cognitive alterations and decreases BDNF level in the brain of rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 2. 2021-11-18. PMID:33404066. |
therefore, in the present study, we examined the effects of postnatal days (pnd 10-20) administration of para-chlorophenylalanine (pcpa, 100 mg/kg, s.c) a 5-ht synthesis inhibitor, on anxiety-related behaviors, pain sensitivity, short-term recognition memory, and hippocampal and prefrontal cortex (pfc) brain-derived neurotrophic factor (bdnf) mrna expression in adult male and female rats. |
2021-11-18 |
2023-08-13 |
rat |
| Hakimeh Saadati, Farshid Sadegzadeh, Nona Sakhaie, Hamdollah Panahpour, Mohsen Sagh. Serotonin depletion during the postnatal developmental period causes behavioral and cognitive alterations and decreases BDNF level in the brain of rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 2. 2021-11-18. PMID:33404066. |
in addition, postnatal days serotonin depletion decreased bdnf level in the hippocampus and pfc of both male and female rats. |
2021-11-18 |
2023-08-13 |
rat |
| María Eugenia Pallarés, Melisa Carolina Monteleone, Verónica Pastor, Jazmín Grillo Balboa, Ana Alzamendi, Marcela Adriana Brocco, Marta Cristina Antonell. Early-Life Stress Reprograms Stress-Coping Abilities in Male and Female Juvenile Rats. Molecular neurobiology. vol 58. issue 11. 2021-11-18. PMID:34409559. |
in the hippocampus, ps increased the expression of bdnf-iv and crfr1 and induced sex difference changes on glucocorticoids and bdnf mrna receptor levels. |
2021-11-18 |
2023-08-13 |
rat |
| Hui-Hui Miao, Zhuang Miao, Ji-Gang Pan, Xu-Hui Li, Min Zhu. Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice. Molecular brain. vol 14. issue 1. 2021-11-18. PMID:34526080. |
previous studies have demonstrated that brain-derived neurotrophic factor (bdnf) is one of the diffusible messengers for enhancing synaptic transmission in the hippocampus. |
2021-11-18 |
2023-08-13 |
mouse |
| J J Steventon, H L Chandler, C Foster, H Dingsdale, M Germuska, T Massey, G Parker, R G Wise, K Murph. Changes in white matter microstructure and MRI-derived cerebral blood flow after 1-week of exercise training. Scientific reports. vol 11. issue 1. 2021-11-18. PMID:34764358. |
exercise is beneficial for brain health, inducing neuroplasticity and vascular plasticity in the hippocampus, which is possibly mediated by brain-derived neurotrophic factor (bdnf) levels. |
2021-11-18 |
2023-08-13 |
Not clear |
| Liu-Lin Xiong, Jie Chen, Ruo-Lan Du, Jia Liu, Yan-Jun Chen, Mohammed Al Hawwas, Xin-Fu Zhou, Ting-Hua Wang, Si-Jin Yang, Xue Ba. Brain-derived neurotrophic factor and its related enzymes and receptors play important roles after hypoxic-ischemic brain damage. Neural regeneration research. vol 16. issue 8. 2021-11-16. PMID:33433458. |
the mrna expression levels of bdnf and its processing enzymes and receptors (furin, matrix metallopeptidase 9, tissue-type plasminogen activator, tyrosine kinase receptor b, plasminogen activator inhibitor-1, and sortilin) were upregulated in the ipsilateral hippocampus and cerebral cortex 6 hours after injury; however, the expression levels of these mrnas were found to be downregulated in the contralateral hippocampus and cerebral cortex. |
2021-11-16 |
2023-08-13 |
rat |
| Rongrong Cheng, Wenjuan Xu, Junchao Wang, Zhengquan Tang, Min Zhan. The outer membrane protein Amuc_1100 of Akkermansia muciniphila alleviates the depression-like behavior of depressed mice induced by chronic stress. Biochemical and biophysical research communications. vol 566. 2021-11-16. PMID:34129964. |
in addition, amuc_1100 intervention could also improve the down-regulation of brain-derived neurotrophic factor (bdnf) and inflammation in the hippocampus induced by cums. |
2021-11-16 |
2023-08-13 |
mouse |
| XiangFei Liu, JiaLing Zhou, Tian Zhang, Ken Chen, Min Xu, Lei Wu, Jin Liu, YunKe Huang, BinBin Nie, Xu Shen, Ping Ren, Xi Huan. Meranzin hydrate elicits antidepressant effects and restores reward circuitry. Behavioural brain research. vol 398. 2021-11-15. PMID:32905810. |
)-treated rats exhibited decreased depression-like behaviour; increased expression of brain-derived neurotrophic factor (bdnf) in the hippocampal dentate gyrus; and normalized levels of adrenocorticotropic hormone (acth), corticosterone (cort), and acylated ghrelin (ag). |
2021-11-15 |
2023-08-13 |
rat |
| Yufang Si, Xing Xue, Si Liu, Caixia Feng, Huiping Zhang, Sisi Zhang, Yating Ren, Hengyu Ma, Yankai Dong, Hui Li, Longshan Xie, Zhongliang Zh. CRTC1 signaling involvement in depression-like behavior of prenatally stressed offspring rat. Behavioural brain research. vol 399. 2021-11-15. PMID:33161032. |
it was also found decreased levels of total crtc1, nuclear crtc1, calcineurin, brain-derived neurotrophic factor (bdnf) and c-fos, but increased cytoplasmic p-crtc1 in the hippocampus (hip) and prefrontal cortex (pfc) of the offspring rats. |
2021-11-15 |
2023-08-13 |
rat |
| Ling Liu, Chun-Hui Ji, Yuan Wang, Jie Zhao, Yue Liu, Wen-Qian Tang, Jiang-Hong Gu, Bo Jian. Antidepressant-like activity of L-701324 in mice: A behavioral and neurobiological characterization. Behavioural brain research. vol 399. 2021-11-15. PMID:33276033. |
repeated injection of l-701,324 not only prevented cums-induced depressive-like behaviors in mice, but also ameliorated the downregulating effects of cums on the hippocampal bdnf signaling cascade and neurogenesis. |
2021-11-15 |
2023-08-13 |
mouse |
| Ling Liu, Chun-Hui Ji, Yuan Wang, Jie Zhao, Yue Liu, Wen-Qian Tang, Jiang-Hong Gu, Bo Jian. Antidepressant-like activity of L-701324 in mice: A behavioral and neurobiological characterization. Behavioural brain research. vol 399. 2021-11-15. PMID:33276033. |
k252a administration also abolished the activating actions of l-701,324 on the hippocampal bdnf signaling cascade and neurogenesis in cums-treated mice. |
2021-11-15 |
2023-08-13 |
mouse |
| Ling Liu, Chun-Hui Ji, Yuan Wang, Jie Zhao, Yue Liu, Wen-Qian Tang, Jiang-Hong Gu, Bo Jian. Antidepressant-like activity of L-701324 in mice: A behavioral and neurobiological characterization. Behavioural brain research. vol 399. 2021-11-15. PMID:33276033. |
collectively, these data indicated that l-701,324 possesses antidepressant-like activity in mice, which was mediated, at least in part, by promoting the hippocampal bdnf system. |
2021-11-15 |
2023-08-13 |
mouse |
| Laura Martínez-Drudis, Laura Amorós-Aguilar, Meritxell Torras-Garcia, Bruna Serra-Elias, David Costa-Miserachs, Isabel Portell-Cortés, Margalida Coll-Andre. Delayed voluntary physical exercise restores "when" and "where" object recognition memory after traumatic brain injury. Behavioural brain research. vol 400. 2021-11-15. PMID:33279639. |
the aims of this work were to: 1) assess whether voluntary physical exercise can reduce the deficits associated with traumatic brain injury (tbi) in two different components of episodic-like memory based on object recognition, temporal order memory ("when"), and object location memory ("where"); and 2) determine whether changes in levels of brain-derived neurotrophic factor (bdnf) in the hippocampus and prefrontal cortex, as well as alterations in hippocampal cytokines, insulin-like growth factor-1 (igf-1) and vascular endothelial growth factor (vegf), may influence the effects exercise has on either or both tasks. |
2021-11-15 |
2023-08-13 |
rat |
| Laura Martínez-Drudis, Laura Amorós-Aguilar, Meritxell Torras-Garcia, Bruna Serra-Elias, David Costa-Miserachs, Isabel Portell-Cortés, Margalida Coll-Andre. Delayed voluntary physical exercise restores "when" and "where" object recognition memory after traumatic brain injury. Behavioural brain research. vol 400. 2021-11-15. PMID:33279639. |
physical exercise restored the "when" and "where" memories, which had been impaired by the tbi, and increased the concentration of bdnf in the hippocampus, but not the prefrontal cortex. |
2021-11-15 |
2023-08-13 |
rat |
| Mingyue Zhao, Zemeng Zhu, Haonan Li, Wei Wang, Shuyue Cheng, Xiaqing Qin, Huiran Wu, Dexiang Liu, Fang Pa. Effects of traumatic stress in adolescence on PTSD-like behaviors, dendrite development, and H3K9me2/BDNF expression in the amygdala of male rats. Journal of affective disorders. vol 296. 2021-11-15. PMID:34619155. |
in a previous experiment, we demonstrated that traumatic stress in adolescence triggers changes in the expression of the epigenetic marker h3k9me2 in the hippocampus and prefrontal cortex of adolescent and adult rats, which suppresses transcription of the brain-derived neurotrophic factor (bdnf) gene that promotes dendrite development and synaptic growth. |
2021-11-15 |
2023-08-13 |
rat |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Robson Luiz Oliveira Santos, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Effects of long-term social isolation on central, behavioural and metabolic parameters in middle-aged mice. Behavioural brain research. vol 417. 2021-11-15. PMID:34656691. |
immunohistochemistry in the hippocampus (Δfosb, bdnf, and 8ohdg) and hypothalamus (Δfosb) was also performed. |
2021-11-15 |
2023-08-13 |
mouse |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Robson Luiz Oliveira Santos, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Effects of long-term social isolation on central, behavioural and metabolic parameters in middle-aged mice. Behavioural brain research. vol 417. 2021-11-15. PMID:34656691. |
the isolated group showed impaired memory along with a decrease in hippocampal Δfosb at dentate gyrus and in bdnf at ca3. |
2021-11-15 |
2023-08-13 |
mouse |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Robson Luiz Oliveira Santos, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Effects of long-term social isolation on central, behavioural and metabolic parameters in middle-aged mice. Behavioural brain research. vol 417. 2021-11-15. PMID:34656691. |
moreover, short-term memory deficit was associated with lower levels of hippocampal Δfosb and bdnf in middle age. |
2021-11-15 |
2023-08-13 |
mouse |