| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Subrina Jesmin, Takeru Shima, Mariko Soya, Kanako Takahashi, Koki Omura, Kasane Ogura, Hikaru Koizumi, Hideaki Soy. Long-term light and moderate exercise intervention similarly prevent both hippocampal and glycemic dysfunction in pre-symptomatic type 2 diabetic rats. American journal of physiology. Endocrinology and metabolism. 2021-12-27. PMID:34957860. |
four months of light or moderate exercise from the pre-symptomatic stage of t2dm normalized glycemic parameters and also hippocampal molecular normalization through mct2, glycogen, and brain-derived neurotrophic factor (bdnf) levels with the improvement of memory dysfunction in oletf rats. |
2021-12-27 |
2023-08-13 |
rat |
| Subrina Jesmin, Takeru Shima, Mariko Soya, Kanako Takahashi, Koki Omura, Kasane Ogura, Hikaru Koizumi, Hideaki Soy. Long-term light and moderate exercise intervention similarly prevent both hippocampal and glycemic dysfunction in pre-symptomatic type 2 diabetic rats. American journal of physiology. Endocrinology and metabolism. 2021-12-27. PMID:34957860. |
a four-month exercise regimen from the pre-symptomatic stage of t2dm at light and moderate intensities contributed to the prevention of the development of t2dm and the progression of cognitive decline with hippocampal lactate-transport and bdnf improvement. |
2021-12-27 |
2023-08-13 |
rat |
| Yulia V Vakhitova, Tatiana S Kalinina, Liana F Zainullina, Anastasiya Yu Lusta, Anna V Volkova, Nikita V Kudryashov, Tatiana A Gudasheva, Alexander A Shimshirt, Ilya A Kadnikov, Mikhail V Voronin, Sergei B Seredeni. Analysis of Antidepressant-like Effects and Action Mechanisms of GSB-106, a Small Molecule, Affecting the TrkB Signaling. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948177. |
in addition, chronic per os administration of gsb-106 resulted in an increase in bdnf levels, which were found to be decreased in the prefrontal cortex and hippocampus of mice after ucms. |
2021-12-24 |
2023-08-13 |
mouse |
| Safa Ghaheri, Hamdopllah Panahpour, Maryam Abdollahzadeh, Hakimeh Saadat. Adolescent enriched environment exposure alleviates cognitive impairment in sleep-deprived male rats: Role of hippocampal BDNF. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2021-12-22. PMID:34937120. |
adolescent enriched environment exposure alleviates cognitive impairment in sleep-deprived male rats: role of hippocampal bdnf. |
2021-12-22 |
2023-08-13 |
rat |
| Safa Ghaheri, Hamdopllah Panahpour, Maryam Abdollahzadeh, Hakimeh Saadat. Adolescent enriched environment exposure alleviates cognitive impairment in sleep-deprived male rats: Role of hippocampal BDNF. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2021-12-22. PMID:34937120. |
the present study aims to examine the long-term effects of the enriched environment (ee), which was imposed during the adolescence period of life, on their passive avoidance and recognition memories as well as anxiety-like behaviors and hippocampal brain-derived neurotrophic factor (bdnf) levels, in sleep-deprived male rats. |
2021-12-22 |
2023-08-13 |
rat |
| Safa Ghaheri, Hamdopllah Panahpour, Maryam Abdollahzadeh, Hakimeh Saadat. Adolescent enriched environment exposure alleviates cognitive impairment in sleep-deprived male rats: Role of hippocampal BDNF. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2021-12-22. PMID:34937120. |
the expression of hippocampal bdnf levels was determined by pcr. |
2021-12-22 |
2023-08-13 |
rat |
| Safa Ghaheri, Hamdopllah Panahpour, Maryam Abdollahzadeh, Hakimeh Saadat. Adolescent enriched environment exposure alleviates cognitive impairment in sleep-deprived male rats: Role of hippocampal BDNF. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2021-12-22. PMID:34937120. |
in addition, ee reversed sd-induced changes in hippocampal bdnf level. |
2021-12-22 |
2023-08-13 |
rat |
| Safa Ghaheri, Hamdopllah Panahpour, Maryam Abdollahzadeh, Hakimeh Saadat. Adolescent enriched environment exposure alleviates cognitive impairment in sleep-deprived male rats: Role of hippocampal BDNF. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2021-12-22. PMID:34937120. |
the increase of the bdnf level in the hippocampus is a possible mechanism to alleviate cognitive performance in sleep-deprived rats. |
2021-12-22 |
2023-08-13 |
rat |
| Zhiqiang Lu, Xiaomeng Xu, Dongmei Li, Na Sun, Songyi Li. Sea Cucumber Peptides Attenuated the Scopolamine-Induced Memory Impairment in Mice and Rats and the Underlying Mechanism. Journal of agricultural and food chemistry. 2021-12-21. PMID:34932331. |
scp repaired damaged neuronal cells, enhanced the nissl body number, increased the unsaturated lipid level, and activated the long-term potentiation (ltp) pathway (p-camkii, p-creb, and bdnf), both in the mouse and rat hippocampus. |
2021-12-21 |
2023-08-13 |
mouse |
| b' Lale G\\xc3\\xb6nenir Erbay, R\\xc4\\xb1fat Karl\\xc4\\xb1da\\xc4\\x9f, M\\xc3\\xbccahit Oru\\xc3\\xa7, Y\\xc4\\xb1lmaz \\xc3\\x87i\\xc4\\x9fremi\\xc5\\x9f, Osman Celbi\\xc5\\x9. Association of BDNF / TrkB and NGF / TrkA Levels in Postmortem Brain with Major Depression and Suicide. Psychiatria Danubina. vol 33. issue 4. 2021-12-20. PMID:34928896.' |
this study was conducted to examine whether bdnf and / or trkb as well as ngf and / or trka expression profiles were changed in the hippocampus of postmortem brain of individuals with depression who committed suicide. |
2021-12-20 |
2023-08-13 |
Not clear |
| Saeid Fakhraei, Mohammad Reza Almasi, Maghsoud Peeri, Reza Gharakhanlo. The effect of 4-Week rehabilitation by aerobic exercise on hippocampus BDNF and TGF-β1 gene expressions inAβ 1-42-induced rat model of Alzheimer's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 95. 2021-12-20. PMID:34929632. |
the effect of 4-week rehabilitation by aerobic exercise on hippocampus bdnf and tgf-β1 gene expressions inaβ 1-42-induced rat model of alzheimer's disease. |
2021-12-20 |
2023-08-13 |
rat |
| Saeid Fakhraei, Mohammad Reza Almasi, Maghsoud Peeri, Reza Gharakhanlo. The effect of 4-Week rehabilitation by aerobic exercise on hippocampus BDNF and TGF-β1 gene expressions inAβ 1-42-induced rat model of Alzheimer's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 95. 2021-12-20. PMID:34929632. |
this study aimed to determine the effect of 4 weeks of aerobic rehabilitation exercise (rhexe) on the genes expression of bdnf and tgf-β1 in the hippocampus tissue of rats with the ad induced by injection of amyloid-beta (aβ |
2021-12-20 |
2023-08-13 |
rat |
| Hiroyuki Umegaki, Takashi Sakurai, Hidenori Ara. Active Life for Brain Health: A Narrative Review of the Mechanism Underlying the Protective Effects of Physical Activity on the Brain. Frontiers in aging neuroscience. vol 13. 2021-12-17. PMID:34916925. |
the most intensively studied mechanisms of the beneficial effects of pa involve an increase in brain-derived neurotrophic factor (bdnf) and preservation of brain volume, especially that of the hippocampus. |
2021-12-17 |
2023-08-13 |
human |
| Ghasem Majdi Yazdi, Gholamhasan Vaezi, Vida Hojati, Mohammad Mohammad-Zade. The Effect of 6-gingerol on Growth Factors and Apoptosis Indices in Rats Exposed to Gold Nanoparticles. Basic and clinical neuroscience. vol 12. issue 3. 2021-12-17. PMID:34917289. |
given the antioxidant properties of gingerol (ging), this study aimed to determine the protective effect of 6-gingerol on hippocampal levels of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), dna oxidative damage, and the amount of bax and bcl2 apoptosis indices of rats exposed to aunps. |
2021-12-17 |
2023-08-13 |
rat |
| Naeemeh Khalesi, Mojgan Bandehpour, Mohammad Reza Bigdeli, Hassan Niknejad, Ali Dabbagh, Bahram Kazem. 14-3-3ζ protein protects against brain ischemia/reperfusion injury and induces BDNF transcription after MCAO in rat. Journal of applied biomedicine. vol 17. issue 2. 2021-12-15. PMID:34907731. |
the present study showed that 14-3-3ζ could up-regulate bdnf mrna at early time point after ischemia in the hippocampus, in the cortex and in the piriform cortex-amygdala and could also improve neurological outcome and reduce infarct volume. |
2021-12-15 |
2023-08-13 |
human |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
these two factors can modify areas related to memory and learning as the hippocampus, through mechanisms related to the gene expression of brain-derived neurotrophic factor (bdnf). |
2021-12-15 |
2023-08-13 |
rat |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
in addition, these changes in early life may affect the functioning of the hippocampus during adulthood through mechanisms mediated by bdnf. |
2021-12-15 |
2023-08-13 |
rat |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
thereby, evidence from the scientific literature suggests that the mechanisms of synaptic plasticity in the hippocampus of adult animals are influenced by malnutrition and ee, and these alterations may involve the participation of bdnf as a key regulator in memory processes in the adult animal hippocampus. |
2021-12-15 |
2023-08-13 |
rat |
| Nader Asadian, Houman Parsaie, Abbas Ali Vafaei, Masoumeh Dadkhah, Samira Omoumi, Katayoun Sedagha. Chronic light deprivation induces different effects on spatial and fear memory and hippocampal BDNF/TRKB expression during light and dark phases of rat diurnal rhythm. Behavioural brain research. vol 418. 2021-12-11. PMID:34695541. |
bdnf and trkb protein levels in the hippocampus of rats from the four sub-groups were measured by western blot, at the completion of the 3 week constant darkness exposure and after the behavioral experiments. |
2021-12-11 |
2023-08-13 |
human |
| Azam Moosavi Sohroforouzani, Saeed Shakerian, Mohsen Ghanbarzadeh, Hojjatallah Alae. Effect of forced treadmill exercise on stimulation of BDNF expression, depression symptoms, tactile memory and working memory in LPS-treated rats. Behavioural brain research. vol 418. 2021-12-11. PMID:34743949. |
this study aimed to investigate the effect of forced treadmill exercise on hippocampal bdnf expression levels, depression symptoms, tactile memory and working memory in lipopolysaccharide (lps)-treated rats. |
2021-12-11 |
2023-08-13 |
rat |