| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jin Li, Xiaobin Zhang, Jiangling Jiang, Bin Zhang, Yingying Tang, Tianhong Zhang, Yuping Jia, Qingwei Li, Mengqing Xia, Jianhua Sheng, Chunbo Li, Jijun Wan. Comparison of electroconvulsive therapy and magnetic seizure therapy in schizophrenia: Structural changes/neuroplasticity. Psychiatry research. vol 312. 2022-04-04. PMID:35378453. |
in addition, we examined the possible contributions of hippocampal volume changes and enhanced brain derived neurotrophic factor (bdnf) signaling to the therapeutic responses. |
2022-04-04 |
2023-08-13 |
Not clear |
| Peng Wang, Peiyu Guo, Yanhui Wang, Xiangyun Teng, Huaqi Zhang, Lirui Sun, Meilan Xue, Hui Lian. Propolis Ameliorates Alcohol-Induced Depressive Symptoms in C57BL/6J Mice by Regulating Intestinal Mucosal Barrier Function and Inflammatory Reaction. Nutrients. vol 14. issue 6. 2022-03-26. PMID:35334870. |
in addition, propolis attenuates the injury of nerve cells in the hippocampal region and restores the serum levels of brain-derived neurotrophic factor (bdnf) and dopamine (da) in mice with alcohol-induced depression. |
2022-03-26 |
2023-08-13 |
mouse |
| Lichi Xu, Yanjing Guo, Gongming Wang, Guoqing Sun, Wei Sun, Jingjing Li, Xinlei Li, Jiangnan Wu, Mengyuan Zhan. Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways. Frontiers in aging neuroscience. vol 14. 2022-03-21. PMID:35309893. |
hippocampal brain-derived neurotrophic factor (bdnf) or neurotrophin-3 (nt-3) microinjection could partially improve the sevoflurane-induced cognitive impairment and ahn inhibition, respectively. |
2022-03-21 |
2023-08-13 |
mouse |
| Lívia Ferraz D'avila, Verônica Tironi Dias, Fabíola Trevizol, Vinícia Garzella Metz, Karine Roversi, Laura Milanesi, Luana Haselein Maurer, Júlia Baranzelli, Tatiana Emanuelli, Marilise Escobar Burge. INTERESTERIFIED FAT MATERNAL CONSUMPTION BEFORE CONCEPTION PROGRAMMS MEMORY AND LEARNING OF ADULTHOOD OFFSPRING: how big is this deleterious repercussion? Toxicology letters. 2022-03-18. PMID:35301046. |
maternal if consumption before conception decreased hippocampal palmitoleic acid incorporation, probdnf and bdnf levels, decreasing both exploratory activity and memory performance in adult offspring. |
2022-03-18 |
2023-08-13 |
rat |
| Gordana D Vitaliano, Jae K Kim, Marc J Kaufman, Christopher W Adam, Gonzalo Zeballos, Abinaya Shanmugavadivu, Sivan Subburaju, Jay P McLaughlin, Scott E Lukas, Franco Vitalian. Clathrin-nanoparticles deliver BDNF to hippocampus and enhance neurogenesis, synaptogenesis and cognition in HIV/neuroAIDS mouse model. Communications biology. vol 5. issue 1. 2022-03-18. PMID:35301411. |
clathrin-nanoparticles deliver bdnf to hippocampus and enhance neurogenesis, synaptogenesis and cognition in hiv/neuroaids mouse model. |
2022-03-18 |
2023-08-13 |
mouse |
| Gordana D Vitaliano, Jae K Kim, Marc J Kaufman, Christopher W Adam, Gonzalo Zeballos, Abinaya Shanmugavadivu, Sivan Subburaju, Jay P McLaughlin, Scott E Lukas, Franco Vitalian. Clathrin-nanoparticles deliver BDNF to hippocampus and enhance neurogenesis, synaptogenesis and cognition in HIV/neuroAIDS mouse model. Communications biology. vol 5. issue 1. 2022-03-18. PMID:35301411. |
here, we show that engineered clathrin triskelia (ct) conjugated to bdnf (bdnf-ct) and delivered intranasally increased hippocampal bdnf concentrations 400-fold above that achieved previously with intranasal bdnf alone. |
2022-03-18 |
2023-08-13 |
mouse |
| Li-Kuan Wang, Xu-Dong Yang, Dan Zhou, Tong Cheng, Xiang Zhang, Hai-Yin W. Prenatal Isoflurane Exposure Induces Developmental Neurotoxicity in Rats: the Role of Gut Microbiota. Neurotoxicity research. 2022-03-16. PMID:35294710. |
we also analyzed hippocampal expression of brain-derived neurotrophic factor (bdnf) in p28 rat brains. |
2022-03-16 |
2023-08-13 |
rat |
| Li-Kuan Wang, Xu-Dong Yang, Dan Zhou, Tong Cheng, Xiang Zhang, Hai-Yin W. Prenatal Isoflurane Exposure Induces Developmental Neurotoxicity in Rats: the Role of Gut Microbiota. Neurotoxicity research. 2022-03-16. PMID:35294710. |
to further explore the role of gut microbiota on prenatal isoflurane-induced developmental neurotoxicity, we treated rats with mixed probiotics on p14 for 14 days and evaluated novel object recognition and hippocampal expression of bdnf on p28. |
2022-03-16 |
2023-08-13 |
rat |
| Li-Kuan Wang, Xu-Dong Yang, Dan Zhou, Tong Cheng, Xiang Zhang, Hai-Yin W. Prenatal Isoflurane Exposure Induces Developmental Neurotoxicity in Rats: the Role of Gut Microbiota. Neurotoxicity research. 2022-03-16. PMID:35294710. |
results indicate that prenatal exposure to isoflurane significantly decreased novel object recognition (novel object preference ratio: mean difference (md) - 0.157; 95% confidence interval (ci) - 0.234 to - 0.080, p < 0.001) paralleled by diminished expression of hippocampal bdnf in juvenile rats. |
2022-03-16 |
2023-08-13 |
rat |
| Princewill Ikechukwu Ugwu, Benneth Ben-Azu, Sandra Ugonne Ugwu, Christian I Uruaka, Chinecherem Choice Nworgu, Pamela Onyinye Okorie, Kizito Oluchukwu Okafor, Kenneth Kelechi Anachuna, Melford Uche Elendu, Amogechukwu Onyinye Ugwu, Ugochukwu Bond Anyaehie, Azubuike A Nwankwo, Eme Effiom Osi. Putative mechanisms involved in the psychopathologies of mice passively coping with psychosocial defeat stress by quercetin. Brain research bulletin. 2022-03-12. PMID:35278662. |
the decreased serotonin in the prefrontal-cortex and dopamine in the striatum, elevated levels of noradrenaline and acetylcholinesterase in the prefrontal-cortex and hippocampus with corresponding decrease in bdnf were reversed by quercetin. |
2022-03-12 |
2023-08-13 |
mouse |
| Emily J Jaehne, Jessica N Kent, Emily J Antolasic, Bradley J Wright, Jereme G Spiers, Kerstin C Creutzberg, Federico De Rosa, Marco A Riva, Caryl E Sortwell, Timothy J Collier, Maarten van den Buus. Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory. Translational psychiatry. vol 12. issue 1. 2022-03-08. PMID:35256586. |
bdnf exon vi expression in the dorsal hippocampus was higher and bdnf protein level in the ventral hippocampus was lower in female val/met rats than female val/val rats, with no other genotype differences, including in total bdnf, bdnf long, or bdnf iv mrna. |
2022-03-08 |
2023-08-13 |
rat |
| Shengying Pan, Yaoying Ma, Rongrong Yang, Xu Lu, Qingsheng You, Ting Ye, Chao Huan. Indole-3-Carbinol Selectively Prevents Chronic Stress-Induced Depression-but not Anxiety-Like Behaviors via Suppressing Pro-Inflammatory Cytokine Production and Oxido-Nitrosative Stress in the Brain. Frontiers in pharmacology. vol 13. 2022-03-04. PMID:35242039. |
further analysis showed that repeated i3c treatment (60 mg/kg, 10 days) prevented csds-induced increases in levels of nitrite and malondialdehyde (mda), decreases in contents of glutathione (gsh), and decreases in levels of brain derived neurotrophic factor (bdnf) protein in the hippocampus and prefrontal cortex. |
2022-03-04 |
2023-08-13 |
mouse |
| Teresa Cramer, Raminder Gill, Zahra S Thirouin, Markus Vaas, Suchita Sampath, Fanny Martineau, Sara B Noya, Patrizia Panzanelli, Tania J J Sudharshan, David Colameo, Philip K-Y Chang, Pei You Wu, Roy Shi, Philip A Barker, Steven A Brown, Rosa C Paolicelli, Jan Klohs, Rebecca Anne McKinney, Shiva K Tyagaraja. Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia. Science advances. vol 8. issue 9. 2022-03-04. PMID:35245123. |
here, using in vitro organotypic hippocampal slice cultures and transient middle cerebral artery occlusion (mcao) in genetically engineered mice in vivo, we report that at 24 hours after ischemia, microglia release brain-derived neurotrophic factor (bdnf) to downregulate glutamatergic and gabaergic synapses within the peri-infarct area. |
2022-03-04 |
2023-08-13 |
mouse |
| Che-Wen Tsai, Shih-Jen Tsai, Yi-Ju Pan, Hsin-Mei Lin, Tsung-Yu Pan, Feng-Yi Yan. Transcranial Ultrasound Stimulation Reverses Behavior Changes and the Expression of Calcium-Binding Protein in a Rodent Model of Schizophrenia. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022-03-01. PMID:35229268. |
in addition, lipus stimulation rebalanced the bdnf levels in the hippocampus and medial prefrontal cortex. |
2022-03-01 |
2023-08-13 |
rat |
| Zofia Rogóż, Kinga Kamińska, Marta Anna Lech, Elżbieta Lorenc-Koc. N-Acetylcysteine and Aripiprazole Improve Social Behavior and Cognition and Modulate Brain BDNF Levels in a Rat Model of Schizophrenia. International journal of molecular sciences. vol 23. issue 4. 2022-02-26. PMID:35216241. |
the aim of our study was to compare the efficacy of chronic administration of the atypical antipsychotic drug aripiprazole (7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl] butoxy}-3,4-dihydro-2(1h)-quinolinone; ari) and the well-known antioxidant n-acetylcysteine (nac) both in alleviating schizophrenia-like social and cognitive deficits and in reducing the decreases in the levels of the brain-derived neurotrophic factor (bdnf) in the prefrontal cortex (pfc) and hippocampus (hip) of adult sprague-dawley rats, that have been induced by chronic administration of the model compound l-buthionine-(s, r)-sulfoximine (bso) during the early postnatal development (p5-p16). |
2022-02-26 |
2023-08-13 |
rat |
| Changjing Zhang, Leilei Zhu, Shuaifei Lu, Mengyuan Li, Ming Bai, Yucheng Li, Erping X. The antidepressant-like effect of formononetin on chronic corticosterone-treated mice. Brain research. 2022-02-26. PMID:35218705. |
moreover, fmn reduced the serum corticosterone levels, upregulated the protein expression levels of the glucocorticoid receptor (gr), and brain-derived neurotrophic factor (bdnf) in the hippocampus, protected against the cort-induced neuronal impairment, and promoted the neurogenesis in the hippocampus. |
2022-02-26 |
2023-08-13 |
mouse |
| Nayere Askari, Ali Mousavi, Mohammad Reza Vaez-Mahdav. Maternal deprivation effect on morphine-induced CPP is related to changes in Opioid receptors in selected rat brain regions (hippocampus, prefrontal cortex, and nucleus accumbens). Behavioural processes. 2022-02-26. PMID:35218881. |
a significant decrease was observed in the expression of bdnf gene (in all of the selected brain regions) and gr (glucocorticoid receptor) gene (in the hippocampus and nucleus accumbens) in md rats. |
2022-02-26 |
2023-08-13 |
rat |
| Matthew Marion, John Hamilton, Brittany Richardson, Nicole Roeder, Antonio Figueiredo, Amanda Nubelo, Eleftherios Hetelekides, Samantha Penman, Yuji Owada, Yoshiteru Kagawa, Panayotis K Thano. Environmental Enrichment Sex-dependently Rescues Memory Impairment in FABP5 KO Mice Not Mediated by Brain-Derived Neurotrophic Factor. Behavioural brain research. 2022-02-24. PMID:35202717. |
mice were then euthanized to assess hippocampal brain-dervied neurotrophic factor (bdnf) concentrations. |
2022-02-24 |
2023-08-13 |
mouse |
| Matthew Marion, John Hamilton, Brittany Richardson, Nicole Roeder, Antonio Figueiredo, Amanda Nubelo, Eleftherios Hetelekides, Samantha Penman, Yuji Owada, Yoshiteru Kagawa, Panayotis K Thano. Environmental Enrichment Sex-dependently Rescues Memory Impairment in FABP5 KO Mice Not Mediated by Brain-Derived Neurotrophic Factor. Behavioural brain research. 2022-02-24. PMID:35202717. |
lastly, environmental enrichment increased hippocampal bdnf levels in male wt mice only. |
2022-02-24 |
2023-08-13 |
mouse |
| Pingping Tan, Ting Xue, Yue Wang, Zhichao Hu, Jianbin Su, Rongrong Yang, Jianlin Ji, Minxiu Ye, Zhuo Chen, Chao Huang, Xu L. Hippocampal NR6A1 impairs CREB-BDNF signaling and leads to the development of depression-like behaviors in mice. Neuropharmacology. 2022-02-20. PMID:35183538. |
chronic stress exposure is a risk factor that can induce the development of depression-like behaviors by impairing the hippocampal cyclic adenosine monophosphate-response element binding protein (creb)-brain-derived neurotrophic factor (bdnf) signaling, but its underlying mechanisms remain largely unknown. |
2022-02-20 |
2023-08-13 |
mouse |