| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Itsuki Kageyama, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Ryosuke Fujii, Yuki Nouchi, Takuya Wakasugi, Tomohide Sakakibara, Atsushi Teshigawara, Hiroaki Ishikawa, Yohei Shimono, Koji Suzuki, Shuji Hashimoto, Koji Ohash. Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence. PloS one. vol 17. issue 6. 2022-06-17. PMID:35714129. |
we analyzed mrna and protein levels for qpcr and western blotting, respectively, of a hippocampal nf, brain-derived neurotrophic factor (bdnf). |
2022-06-17 |
2023-08-14 |
rat |
| Itsuki Kageyama, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Ryosuke Fujii, Yuki Nouchi, Takuya Wakasugi, Tomohide Sakakibara, Atsushi Teshigawara, Hiroaki Ishikawa, Yohei Shimono, Koji Suzuki, Shuji Hashimoto, Koji Ohash. Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence. PloS one. vol 17. issue 6. 2022-06-17. PMID:35714129. |
hfcs consumption reduced hippocampal bdnf mrna and protein expressions in childhood and adolescence. |
2022-06-17 |
2023-08-14 |
rat |
| Sneha Sagarkar, Nagashree Bhat, Madhura Sapre, Biru Dudhabhate, Dadasaheb M Kokare, Nishikant K Subhedar, Amul J Sakharka. TET1-induced DNA demethylation in dentate gyrus is important for reward conditioning and reinforcement. Molecular neurobiology. 2022-06-15. PMID:35705787. |
the hippocampus of conditioned rats displayed higher mrna levels of ten-eleven translocase 1 (tet1) and brain-derived neurotrophic factor (bdnf) after memory probe trial. |
2022-06-15 |
2023-08-14 |
rat |
| Sneha Sagarkar, Nagashree Bhat, Madhura Sapre, Biru Dudhabhate, Dadasaheb M Kokare, Nishikant K Subhedar, Amul J Sakharka. TET1-induced DNA demethylation in dentate gyrus is important for reward conditioning and reinforcement. Molecular neurobiology. 2022-06-15. PMID:35705787. |
the tet1-induced dna demethylation at the bdnf promoters raised bdnf levels in the hippocampus, thereby setting the stage for reward memory retrieval. |
2022-06-15 |
2023-08-14 |
rat |
| Solange de Souza Stork, Marcos Hübner, Erica Biehl, Lucineia Gainski Danielski, Sandra Bonfante, Larissa Joaquim, Tais Denicol, Thaina Cidreira, Anita Pacheco, Erick Bagio, Everton Lanzzarin, Gabriela Bernades, Mariana Pacheco de Oliveira, Larissa Espindola da Silva, Josiel M Mack, Franciane Bobinski, Gislaine Tezza Rezin, Tatiana Barichello, Emilio Luiz Streck, Fabricia Petronilh. Diabetes Exacerbates Sepsis-Induced Neuroinflammation and Brain Mitochondrial Dysfunction. Inflammation. 2022-06-10. PMID:35689164. |
levels of il-6, il-10, brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), and mitochondrial respiratory chain complexes were evaluated in the hippocampus and prefrontal cortex 24 h after sepsis by cecal ligation and perforation (clp) in wistar rats induced to type 1 diabetes by alloxan (150 mg/kg). |
2022-06-10 |
2023-08-14 |
rat |
| Mohsen Sheykhhasan, Razieh Amini, Sara Soleimani Asl, Massoud Saidijam, Seyed Mahmoud Hashemi, Rezvan Najaf. Neuroprotective effects of coenzyme Q10-loaded exosomes obtained from adipose-derived stem cells in a rat model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-09. PMID:35679720. |
according to the findings of this study, exo+ coq10 enhanced cognition and memory deficiency in alzheimer's disease by boosting bdnf and sox2 levels in the hippocampus. |
2022-06-09 |
2023-08-14 |
rat |
| Martina Stazi, Silvia Zampar, Madeleine Nadolny, Luca Büschgens, Thomas Meyer, Oliver Wirth. Combined long-term enriched environment and caffeine supplementation improve memory function in C57Bl6 mice. European archives of psychiatry and clinical neuroscience. 2022-06-08. PMID:35676374. |
mice housed under ee conditions showed increased gene expression levels of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2022-06-08 |
2023-08-14 |
mouse |
| Asma Batool, Sadia Saleem, Fizza Naqvi, Khwaja Ali Hasan, Faizan Naqvi, Saida Haide. Thymol mitigates cadmium-induced behavioral and cognitive deficits by up-regulating hippocampal BDNF levels in rats. Pakistan journal of pharmaceutical sciences. vol 35. issue 2(Special). 2022-06-07. PMID:35668569. |
thymol mitigates cadmium-induced behavioral and cognitive deficits by up-regulating hippocampal bdnf levels in rats. |
2022-06-07 |
2023-08-14 |
human |
| Asma Batool, Sadia Saleem, Fizza Naqvi, Khwaja Ali Hasan, Faizan Naqvi, Saida Haide. Thymol mitigates cadmium-induced behavioral and cognitive deficits by up-regulating hippocampal BDNF levels in rats. Pakistan journal of pharmaceutical sciences. vol 35. issue 2(Special). 2022-06-07. PMID:35668569. |
brain sample were collected and bdnf was measured in hippocampus. |
2022-06-07 |
2023-08-14 |
human |
| Yun-Ting Wang, Han Wang, Wu-Jiang Ren, Xue-Ling Dai, Qing Huo, Shuo Wang, Ya-Xuan Su. 3,6'-Disinapoylsucrose alleviates the amyloid precursor protein and lipopolysaccharide induced cognitive dysfunction through upregulation of the TrkB/BDNF pathway. Journal of Asian natural products research. 2022-06-07. PMID:35672874. |
diss can regulate tyrosine kinase b (trkb)/brain-derived neurotrophic factor (bdnf) signaling in the hippocampus. |
2022-06-07 |
2023-08-14 |
mouse |
| Jatinder Dhaliwal, Navneet Dhaliwal, Ansab Akhtar, Anurag Kuhad, Kanwaljit Chopr. Tetramethylpyrazine Attenuates Cognitive Impairment Via Suppressing Oxidative Stress, Neuroinflammation, and Apoptosis in Type 2 Diabetic Rats. Neurochemical research. 2022-06-06. PMID:35665448. |
furthermore, treatment with tmp increased bdnf, p-akt, and p-creb levels, normalized cholinergic dysfunction, and suppressed oxidative, inflammatory, and apoptotic markers in the hippocampus. |
2022-06-06 |
2023-08-14 |
rat |
| Weisheng Li, Likui Lu, Dan Zhu, Jingliu Liu, Yajun Shi, Hongtao Zeng, Xi Yu, Jun Guo, Bin Wei, Yongle Cai, Miao Su. Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway. Ecotoxicology and environmental safety. vol 239. 2022-06-01. PMID:35643027. |
in addition, in vivo experiment demonstrated that the protein abundance of bdnf and the ratio of p-creb1 to creb1 were increased in the hippocampus of naf offspring, while the level of trkb was reduced. |
2022-06-01 |
2023-08-13 |
mouse |
| Youness Kadil, Houda Filal. Nigella Fixed Oil mitigates memory impairment in a rat aged model of cognitive decline, a pivotal role of BDNF and CREB signaling pathways in the hippocampus. CNS & neurological disorders drug targets. 2022-05-31. PMID:35638539. |
nigella fixed oil mitigates memory impairment in a rat aged model of cognitive decline, a pivotal role of bdnf and creb signaling pathways in the hippocampus. |
2022-05-31 |
2023-08-13 |
rat |
| Tae-Woon Kim, Sang-Seo Park, Hye-Sang Par. Effects of Exercise Training during Advanced Maternal Age on the Cognitive Function of Offspring. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628329. |
we found that the offspring of mothers with ama without exercise training had decreased spatial learning and memory, brain-derived neurotrophic factor (bdnf) and postsynaptic density protein 95 (psd-95) protein levels, neurogenesis, and mitochondrial function, as well as hippocampal cell death. |
2022-05-28 |
2023-08-13 |
Not clear |
| Tae-Woon Kim, Sang-Seo Park, Hye-Sang Par. Effects of Exercise Training during Advanced Maternal Age on the Cognitive Function of Offspring. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628329. |
the maternal exercises augmented the hippocampal levels of bdnf, which prevents decreased cognitive function in the offspring of mothers with ama. |
2022-05-28 |
2023-08-13 |
Not clear |
| Yaran Gao, Ming Hu, Xiaoli Niu, Meixi Li, Lili Xu, Yining Xiao, Jiawei Zhang, Hebo Wang, Litao Li, Bao Chu, Peiyuan L. Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF- Oxidative medicine and cellular longevity. vol 2022. 2022-05-26. PMID:35615581. |
additionally, nbp promoted both the expression of brain-derived neurotrophic factor (bdnf) and tyrosine receptor kinase b (trkb) in hippocampus tissue. |
2022-05-26 |
2023-08-13 |
mouse |
| Wei-Jia Gu, Chun-Rong Bao, Hong-Yu Xie, Bin Chen, Wan-Qing Lin, Yi Wu, Nian-Hong Wan. [Effect of electroacupuncture invention on activities of PGC-1α/Irisin (FNDC5)/BDNF signaling in cerebral cortex, hippocampus and muscles in focal cerebral ischemic/reperfusion injury rats]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 5. 2022-05-26. PMID:35616417. |
to observe the effect of electroacupuncture(ea) on the expression of peroxisome proliferator-activated receptor gamma coactivators-1-alpha (pgc-1α), irisin and brain-derived neurotrophic factor (bdnf) in the ischemic peripheral cortex, hippocampus and local skeletal muscle in rats with focal cerebral ischemic/reperfusion injury (ci/ri), so as to explore its underlying mechanism of improving of ci/ri. |
2022-05-26 |
2023-08-13 |
rat |
| Kimia Alizadeh, Hamid Moghimi, Ali Golbabaei, Sakineh Alijanpour, Ameneh Rezayo. Post-Weaning Treatment with Probiotic Inhibited Stress-Induced Amnesia in Adulthood Rats: The Mediation of GABAergic System and BDNF/c-Fos Signaling Pathways. Neurochemical research. 2022-05-26. PMID:35618945. |
the hippocampal and prefrontal cortical (pfc) expression levels of bdnf and c-fos were also assessed to show whether the treatments affect the memory-related signaling pathway. |
2022-05-26 |
2023-08-13 |
rat |
| Kimia Alizadeh, Hamid Moghimi, Ali Golbabaei, Sakineh Alijanpour, Ameneh Rezayo. Post-Weaning Treatment with Probiotic Inhibited Stress-Induced Amnesia in Adulthood Rats: The Mediation of GABAergic System and BDNF/c-Fos Signaling Pathways. Neurochemical research. 2022-05-26. PMID:35618945. |
the expression levels of bdnf and c-fos in the pfc and the hippocampus were significantly decreased in the stress animal group. |
2022-05-26 |
2023-08-13 |
rat |
| Kimia Alizadeh, Hamid Moghimi, Ali Golbabaei, Sakineh Alijanpour, Ameneh Rezayo. Post-Weaning Treatment with Probiotic Inhibited Stress-Induced Amnesia in Adulthood Rats: The Mediation of GABAergic System and BDNF/c-Fos Signaling Pathways. Neurochemical research. 2022-05-26. PMID:35618945. |
the muscimol response was compounded with the decreased levels of bdnf and c-fos in the pfc and the hippocampus. |
2022-05-26 |
2023-08-13 |
rat |