| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yosra A Hussien, Dina F Mansour, Somaia A Nada, Sahar S Abd El-Rahman, Rania M Abdelsalam, Amina S Attia, Dalia M El-Tanboul. Linagliptin attenuates thioacetamide-induced hepatic encephalopathy in rats: Modulation of C/EBP-β and CX3CL1/Fractalkine, neuro-inflammation, oxidative stress and behavioral defects. Life sciences. 2022-02-08. PMID:35134437. |
lng modulated taa-induced disturbances in hippocampal amino acids; glutamate, and gaba with a significant increase in hippocampal bdnf. |
2022-02-08 |
2023-08-13 |
rat |
| Muaz Belviranlı, Nilsel Okuda. Differential effects of voluntary and forced exercise trainings on spatial learning ability and hippocampal biomarkers in aged female rats. Neuroscience letters. 2022-02-05. PMID:35121056. |
after the behavioral test, hippocampus tissues were taken for the analysis of synaptophysin, acetylcholinesterase (ache), brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), malondialdehyde (mda), protein carbonyl (pc), glutathione (gsh) and superoxide dismutase (sod). |
2022-02-05 |
2023-08-13 |
rat |
| Muaz Belviranlı, Nilsel Okuda. Differential effects of voluntary and forced exercise trainings on spatial learning ability and hippocampal biomarkers in aged female rats. Neuroscience letters. 2022-02-05. PMID:35121056. |
in the hippocampus tissue, levels of the synaptophysin, bdnf, ngf and sod were higher, but mda levels were lower in the voluntary exercise group than in the control group (p < 0.05). |
2022-02-05 |
2023-08-13 |
rat |
| Ana Paula Moreira, Adriana Fernanda K Vizuete, Lisandra Eda Fusinato Zin, Charlanne Oliveira de Marques, Rafaela Ferreira Pacheco, Miriara B Leal, Carlos-Alberto Gonçalve. The Methylglyoxal/RAGE/NOX-2 Pathway is Persistently Activated in the Hippocampus of Rats with STZ-Induced Sporadic Alzheimer's Disease. Neurotoxicity research. 2022-02-02. PMID:35106732. |
furthermore, reinforcing this possibility, we found a reduction in cholinergic communication in the hippocampus (as shown by decreased choline acetyltransferase), a reduction in bdnf, and an increase in tgf-β, the combination of which may result in synaptic deterioration. |
2022-02-02 |
2023-08-13 |
rat |
| Bingyi Liu, Ning Zhang, Junrong Yang, Wei Sun, Ruiyan Zhang, Xuexing Zheng, Zhengping Wang, Hans-Christian Siebert, Jun Ha. Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice. Journal of agricultural and food chemistry. 2022-02-02. PMID:35107277. |
western-blotting analysis displayed that the 2% (w/w) ps emulsion treated group upregulated bdnf, trkb, psd95, mtor, mbp, and erbb4 expression in the hippocampus of 5- and 12-week old mice. |
2022-02-02 |
2023-08-13 |
mouse |
| Maha A Hegazy, Doaa A Abdelmonsif, Teshreen M Zeitoun, Norhan S El-Sayed, Doaa M Sam. Swimming exercise versus L-carnosine supplementation for Alzheimer's dementia in rats: implication of circulating and hippocampal FNDC5/irisin. Journal of physiology and biochemistry. 2022-01-29. PMID:35091983. |
hippocampal tissues were used to assess expression of fndc5/irisin, bdnf and proteins related to insulin signalling, in addition to β-amyloid peptide and phosphorylated tau protein levels. |
2022-01-29 |
2023-08-13 |
rat |
| Maha A Hegazy, Doaa A Abdelmonsif, Teshreen M Zeitoun, Norhan S El-Sayed, Doaa M Sam. Swimming exercise versus L-carnosine supplementation for Alzheimer's dementia in rats: implication of circulating and hippocampal FNDC5/irisin. Journal of physiology and biochemistry. 2022-01-29. PMID:35091983. |
exercise and carnosine intake almost normalized hippocampal fndc5/irisin expression which was associated with reduced soluble β-amyloid peptide and phosphorylated tau protein, improved bdnf and insulin signalling proteins, with corresponding mitigated cognitive impairments. |
2022-01-29 |
2023-08-13 |
rat |
| Roya Malekloo, Setayesh Nematollahi, Abbas Ali Vafaei, Ali Rashidy-Pou. Corrigendum "Effects of different intensities of treadmill exercise on cued fear extinction failure, hippocampal BDNF decline, and Bax/Bcl-2 ratio alteration in chronic- morphine treated male rats" [Behav. Brain Res. 421 (2022) 113732]. Behavioural brain research. vol 422. 2022-01-27. PMID:35085978. |
corrigendum "effects of different intensities of treadmill exercise on cued fear extinction failure, hippocampal bdnf decline, and bax/bcl-2 ratio alteration in chronic- morphine treated male rats" [behav. |
2022-01-27 |
2023-08-13 |
rat |
| Maryam Abdollahzadeh, Hamdollah Panahpour, Safa Ghaheri, Hakimeh Saadat. Calcitriol supplementation attenuates cisplatin-induced behavioral and cognitive impairments through up-regulation of BDNF in male rats. Brain research bulletin. 2022-01-22. PMID:35065185. |
therefore, the present study aims to examine the effects of calcitriol supplementation (100ng/kg /day for five weeks) on cognitive impairment, behavioral deficits, and hippocampal brain-derived neurotrophic factor (bdnf) changes following cisplatin treatment (5mg/kg/ once a week for five weeks). |
2022-01-22 |
2023-08-13 |
rat |
| Maryam Abdollahzadeh, Hamdollah Panahpour, Safa Ghaheri, Hakimeh Saadat. Calcitriol supplementation attenuates cisplatin-induced behavioral and cognitive impairments through up-regulation of BDNF in male rats. Brain research bulletin. 2022-01-22. PMID:35065185. |
besides, hippocampal bdnf levels were reduced in cisplatin-treated rats; however, calcitriol alleviated these effects of cisplatin and up-regulated bdnf mrna in the hippocampus. |
2022-01-22 |
2023-08-13 |
rat |
| Maryam Abdollahzadeh, Hamdollah Panahpour, Safa Ghaheri, Hakimeh Saadat. Calcitriol supplementation attenuates cisplatin-induced behavioral and cognitive impairments through up-regulation of BDNF in male rats. Brain research bulletin. 2022-01-22. PMID:35065185. |
we conclude that increased hippocampal bdnf mediates the beneficial effects of calcitriol against neurotoxicity in cisplatin-exposed rats. |
2022-01-22 |
2023-08-13 |
rat |
| Jamshid Faraji, Hamid Lotfi, Alireza Moharrerie, S Yaghoob Jafari, Nasrin Soltanpour, Rosa Tamannaiee, Kameran Marjani, Shabnam Roudaki, Farhad Naseri, Reza Moeeini, Gerlinde A S Met. Regional Differences in BDNF Expression and Behavior as a Function of Sex and Enrichment Type: Oxytocin Matters. Cerebral cortex (New York, N.Y. : 1991). 2022-01-21. PMID:35059698. |
physical enrichment promoted motor and cognitive functions and hippocampal bdnf mrna and protein expression in both sexes. |
2022-01-21 |
2023-08-13 |
rat |
| Jamshid Faraji, Hamid Lotfi, Alireza Moharrerie, S Yaghoob Jafari, Nasrin Soltanpour, Rosa Tamannaiee, Kameran Marjani, Shabnam Roudaki, Farhad Naseri, Reza Moeeini, Gerlinde A S Met. Regional Differences in BDNF Expression and Behavior as a Function of Sex and Enrichment Type: Oxytocin Matters. Cerebral cortex (New York, N.Y. : 1991). 2022-01-21. PMID:35059698. |
these changes were accompanied by elevated plasma oxytocin (ot) levels and bdnf mrna expression in the mpfc, while the hippocampus was not affected. |
2022-01-21 |
2023-08-13 |
rat |
| b' Alba Toll, Laura Blanco-Hinojo, Daniel Berg\\xc3\\xa9, Xavier Duran, Irene Canosa, Teresa Legido, Federico Marmol, V\\xc3\\xadctor P\\xc3\\xa9rez-Sol\\xc3\\xa0, Emilio Fern\\xc3\\xa1ndez-Egea, Anna Man\\xc3\\xa. Multidimensional predictors of negative symptoms in antipsychotic-naive first-episode psychosis. Journal of psychiatry & neuroscience : JPN. vol 47. issue 1. 2022-01-20. PMID:35046133.' |
the present study aimed to identify baseline clinical or neurobiological factors - including peripheral brain-derived neurotrophic factor (bdnf) levels and amygdala or hippocampal relative volumes - that could predict negative symptomatology and persistent negative symptoms in first-episode psychosis after 1 year of follow-up. |
2022-01-20 |
2023-08-13 |
Not clear |
| Chunping Yin, Qi Zhang, Juan Zhao, Yanan Li, Jiaxu Yu, Wei Li, Qiujun Wan. Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats. Neurochemical research. 2022-01-18. PMID:35040026. |
furthermore, nec-1 remarkably increased bdnf and p-trkb/trkb expression in the hippocampus of aged rats. |
2022-01-18 |
2023-08-13 |
rat |
| Marina F Souza, Katty A A L Medeiros, Lívia C R F Lins, José M M Bispo, Auderlan M Gois, Edson R Santos, Thiago H Almeida-Souza, João E C Melo, Heitor S Franco, Rodolfo S Silva, Eduardo A Pereira-Filho, Marco Aurelio M Freire, José R Santo. Motor, memory, and anxiety-like behavioral impairments associated with brain-derived neurotrophic factor and dopaminergic imbalance after inhalational exposure to deltamethrin. Brain research bulletin. 2022-01-18. PMID:35041849. |
the animals submitted to 9 inhalations of dm showed a reduction in immunoreactivity for th in the substantia nigra pars compacta (snpc), ventral tegmental area (vta), and dorsal striatum (ds) areas, and an increase in bdnf in the ds and ca1, ca3 and dentate gyrus (dg) hippocampal areas. |
2022-01-18 |
2023-08-13 |
rat |
| Marina F Souza, Katty A A L Medeiros, Lívia C R F Lins, José M M Bispo, Auderlan M Gois, Edson R Santos, Thiago H Almeida-Souza, João E C Melo, Heitor S Franco, Rodolfo S Silva, Eduardo A Pereira-Filho, Marco Aurelio M Freire, José R Santo. Motor, memory, and anxiety-like behavioral impairments associated with brain-derived neurotrophic factor and dopaminergic imbalance after inhalational exposure to deltamethrin. Brain research bulletin. 2022-01-18. PMID:35041849. |
conversely, the animals submitted to 15 inhalations of dm showed immunoreactivity reduced for th in the snpc and vta, and an increase in bdnf in the hippocampal areas (ca3 and dg). |
2022-01-18 |
2023-08-13 |
rat |
| Annabel K Short, Viet Bui, Isabel C Zbukvic, Anthony J Hannan, Terence Y Pang, Jee Hyun Ki. Sex-dependent effects of chronic exercise on cognitive flexibility but not hippocampal Bdnf in aging mice. Neuronal signaling. vol 6. issue 1. 2022-01-17. PMID:35036000. |
sex-dependent effects of chronic exercise on cognitive flexibility but not hippocampal bdnf in aging mice. |
2022-01-17 |
2023-08-13 |
mouse |
| Juan Wang, Feng Gao, Shuai Cui, Shaojie Yang, Fang Gao, Xuncui Wang, Guoqi Zh. Utility of 7,8-dihydroxyflavone in preventing astrocytic and synaptic deficits in the hippocampus elicited by PTSD. Pharmacological research. 2022-01-13. PMID:35026406. |
from the perspective of synaptic function, the sps&s model displayed reduced expression of bdnf, p-trkb, postsynaptic density protein 95 (psd95), ampa receptor subunit glur1 (glua1), nmda receptor subunit n2a/n2b ratio, calpain-1, phosphorylated protein kinase b (akt) and phosphorylated mammalian target of rapamycin (mtor) and conversely, higher phosphatase and tension homolog (pten) expression in the hippocampus. |
2022-01-13 |
2023-08-13 |
mouse |
| Alessandro Virtuoso, Pernille Tveden-Nyborg, Anne Marie Voigt Schou-Pedersen, Jens Lykkesfeldt, Heidi Kaastrup Müller, Betina Elfving, Dorte Bratbo Sørense. A Long-Term Energy-Rich Diet Increases Prefrontal BDNF in Sprague-Dawley Rats. Nutrients. vol 14. issue 1. 2022-01-11. PMID:35011001. |
findings of the effect of high-fat feeding including "cafeteria diets" (caf) on brain-derived neurotrophic factor (bdnf) in the hippocampus (hip) and prefrontal cortex (pfc) in rodents are conflicting. |
2022-01-11 |
2023-08-13 |
human |