| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deunsol Hwang, Sunghwan Kyun, Inkwon Jang, Hun-Young Park, Jisu Kim, Kiwon Li. The Effects of Exercise Training with Oral Intake of Lactate on Hippocampal Neurogenesis and Neurotrophic Factors in Mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560403. |
after the experiment ended, hippocampal neurogenesis (ki67, neural stem cell proliferation marker; dcx, marker of differentiation to immature neurons) and neurotrophic factors (pgc1α, fndc5, vegfa, and bdnf) were evaluated respectively by immunohistochemistry (ihc) and by western blot (wb) on hippocampus. |
2022-05-13 |
2023-08-13 |
mouse |
| Bing Su, Suohua Cheng, Lei Wang, Bing Wan. MicroRNA-139-5p acts as a suppressor gene for depression by targeting nuclear receptor subfamily 3, group C, member 1. Bioengineered. vol 13. issue 5. 2022-05-11. PMID:35543383. |
furthermore, compared with the antago-nc group, 3 weeks of antagomir-139-5p treatment significantly decreased mir-139-5p level in model group hippocampus, increased sucrose preference index, reduced neuron damages, and enhanced the levels of nuclear receptor subfamily 3 group c member 1 (nr3c1), brain-derived neurotrophic factor (bdnf), phosphorylated/total tyrosine kinase receptor b (p-trkb/trkb), phosphorylated/total camp-response element-binding protein (p-creb/creb) and phosphorylated/total extracellular regulated protein kinases (p-erk/erk). |
2022-05-11 |
2023-08-13 |
mouse |
| Robert S Gardner, Donna L Korol, Paul E Gol. Hippocampus-sensitive and striatum-sensitive learning one month after morphine or cocaine exposure in male rats. Pharmacology, biochemistry, and behavior. 2022-05-05. PMID:35513118. |
exposure to morphine or cocaine did not significantly change levels of brain-derived neurotrophic factor (bdnf) or a downstream target of bdnf signaling, glycogen synthase kinase 3β (gsk3β), in the hippocampus or striatum. |
2022-05-05 |
2023-08-13 |
rat |
| Stefanie Rauskolb, Thomas Andreska, Sophie Fries, Cora Ruedt von Collenberg, Robert Blum, Camelia-Maria Monoranu, Carmen Villmann, Michael Sendtne. Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment. Acta neuropathologica communications. vol 10. issue 1. 2022-05-05. PMID:35513854. |
neuronal overexpression of igfbp5 prevents the training-induced increase of hippocampal and cortical bdnf expression and reduces the effects of exercise on memory retention, but not on learning acquisition. |
2022-05-05 |
2023-08-13 |
mouse |
| Javad Riyahi, Behrouz Abdoli, Francesca Gelfo, Laura Petrosini, Leila Khatami, Gholam Hossein Meftahi, Abbas Haghparas. Multigenerational effects of paternal spatial training are lasting in the F1 and F2 male offspring. Behavioural pharmacology. 2022-05-03. PMID:35502983. |
further, to investigate the memory process in f1 and f2 male offspring, brain-derived neurotrophic factor (bdnf), p-erk1/2 and acetylated histone 3 lysine 14 (h3k14) expression levels in the hippocampus were analyzed. |
2022-05-03 |
2023-08-13 |
Not clear |
| Javad Riyahi, Behrouz Abdoli, Francesca Gelfo, Laura Petrosini, Leila Khatami, Gholam Hossein Meftahi, Abbas Haghparas. Multigenerational effects of paternal spatial training are lasting in the F1 and F2 male offspring. Behavioural pharmacology. 2022-05-03. PMID:35502983. |
these findings were supported by neurobiologic data showing that paternal training increased bdnf and p-erk1/2 in the hippocampus of f1 and f2 male offspring. |
2022-05-03 |
2023-08-13 |
Not clear |
| Ge Ou, Qian Li, Lin Zhu, Yuanyuan Zhang, Yijing Liu, Xin Li, Lina Du, Yiguang Ji. Intranasal hydrogel of armodafinil hydroxypropyl-β-cyclodextrin inclusion complex for the treatment of post-traumatic stress disorder. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 30. issue 3. 2022-05-02. PMID:35498223. |
besides, the western blot (wb) of hippocampal brain-derived neurotrophic factor (bdnf) and amygdala dopamine transporter (dat) immunohistochemistry sections indicated that aic hydrogel had a protective effect on the brain tissue of ptsd mice. |
2022-05-02 |
2023-08-13 |
mouse |
| Sonia Sanchez-Bezanilla, Daniel J Beard, Rebecca J Hood, N David Åberg, Patricia Crock, Frederick R Walker, Michael Nilsson, Jörgen Isgaard, Lin Kooi On. Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice. Neural plasticity. vol 2022. 2022-04-25. PMID:35465399. |
we aimed to explore the mechanisms of gh treatment by investigating how gh modulates pathways known to induce neuroplasticity, focusing on association between brain-derived neurotrophic factor (bdnf) and mammalian target of rapamycin (mtor) in the peri-infarct area, hippocampus, and thalamus. |
2022-04-25 |
2023-08-13 |
mouse |
| Maria Bove, Stefania Schiavone, Paolo Tucci, Vladyslav Sikora, Stefania Dimonte, Anna Laura Colia, Maria Grazia Morgese, Luigia Trabac. Ketamine administration in early postnatal life as a tool for mimicking Autism Spectrum Disorders core symptoms. Progress in neuro-psychopharmacology & biological psychiatry. 2022-04-23. PMID:35460811. |
possible alterations in levels of brain-derived neurotrophic factor (bdnf) expression in the hippocampus and amygdala were also evaluated. |
2022-04-23 |
2023-08-13 |
mouse |
| Maria Bove, Stefania Schiavone, Paolo Tucci, Vladyslav Sikora, Stefania Dimonte, Anna Laura Colia, Maria Grazia Morgese, Luigia Trabac. Ketamine administration in early postnatal life as a tool for mimicking Autism Spectrum Disorders core symptoms. Progress in neuro-psychopharmacology & biological psychiatry. 2022-04-23. PMID:35460811. |
in addition, we found decreased bdnf and enhanced gfap hippocampal expression levels, accompanied by elevations in glutamate amount, as well as reduction in gaba content in amygdala and hippocampus. |
2022-04-23 |
2023-08-13 |
mouse |
| Kanishk Luhach, Giriraj T Kulkarni, Vijay P Singh, Bhupesh Sharm. Vinpocetine ameliorates developmental hyperserotonemia induced behavioral and biochemical changes: role of neuronal function, inflammation, and oxidative stress. Acta neurobiologiae experimentalis. vol 82. issue 1. 2022-04-22. PMID:35451422. |
also, effects on biochemical markers related with neuronal function brain derived neurotrophic factor (bdnf) and phosphorylated camp response element binding protein (pcreb), inflammation interleukins (il‑6 and il‑10) and tumor necrosis factor-alpha (tnf‑α), and oxidative stress (tbars and gsh) were studied in important brain areas (frontal cortex, cerebellum, hippocampus, and striatum). |
2022-04-22 |
2023-08-13 |
rat |
| Timea Jambor, Gabriella Juhasz, Nora Eszla. Towards personalised antidepressive medicine based on "big data": an up-to-date review on robust factors affecting treatment response. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 24. issue 1. 2022-04-22. PMID:35451589. |
based on our results, onset time, symptom severity, presence of anhedonia, early treatment response, comorbid anxiety, alcohol consumption, frontal eeg theta activity, hippocampal volume, activity of anterior cingulate cortex, as well as a peripheral marker, serum bdnf levels have proven replicable predictors of antidepressant response. |
2022-04-22 |
2023-08-13 |
Not clear |
| Majid Motaghinejad, Manijeh Motevalia. Neuroprotective Properties of Minocycline Against Methylphenidate-Induced Neurodegeneration: Possible Role of CREB/BDNF and Akt/GSK3 Signaling Pathways in Rat Hippocampus. Neurotoxicity research. 2022-04-21. PMID:35446003. |
open field test (oft) (on day 22), forced swim test (fst) (on day 24), and elevated plus maze (on day 26) were conducted to analyze the mood-related behaviors; hippocampal oxidative stress, inflammatory, and apoptotic parameters, as well as the levels of protein kinase b (akt-1), glycogen synthase kinase 3 (gsk3), camp response element-binding protein (creb), and brain-derived neurotrophic factor (bdnf), were also assessed. |
2022-04-21 |
2023-08-13 |
rat |
| Majid Motaghinejad, Manijeh Motevalia. Neuroprotective Properties of Minocycline Against Methylphenidate-Induced Neurodegeneration: Possible Role of CREB/BDNF and Akt/GSK3 Signaling Pathways in Rat Hippocampus. Neurotoxicity research. 2022-04-21. PMID:35446003. |
in the contrary, it increased the levels of reduced form of glutathione (gsh), bcl-2, creb, bdnf, and akt-1 and superoxide dismutase (sod), glutathione peroxidase (gpx), and glutathione reductase (gr) activities in the experimental animals' hippocampus. |
2022-04-21 |
2023-08-13 |
rat |
| Masae Furukawa, Hirobumi Tada, Jingshu Wang, Mitsuyoshi Yamada, Mie Kurosawa, Akiko Satoh, Noboru Ogiso, Yosuke Shikama, Kenji Matsushit. Molar loss induces hypothalamic and hippocampal astrogliosis in aged mice. Scientific reports. vol 12. issue 1. 2022-04-19. PMID:35437315. |
furthermore, in the hypothalamus and hippocampus of molar-extracted aged mice, the transcript-level expression of bdnf, rbfox3, and fos decreased, while that of cdkn2a and aif1 increased. |
2022-04-19 |
2023-08-13 |
mouse |
| Shi-Da Wang, Xue Wang, Yun Zhao, Bing-Hua Xue, Xiao-Tian Wang, Yu-Xin Chen, Zi-Qian Zhang, Ying-Rui Tian, Fang Xie, Ling-Jia Qia. Homocysteine-Induced Disturbances in DNA Methylation Contribute to Development of Stress-Associated Cognitive Decline in Rats. Neuroscience bulletin. 2022-04-18. PMID:35435568. |
the data showed that tet1-expressing viral injection into the hippocampus inhibited bdnf promoter methylation and significantly mitigated the cognitive decline in hhcy rats. |
2022-04-18 |
2023-08-13 |
rat |
| Hajime Miyanishi, Ayumu Kitazawa, Naotaka Izuo, Shin-Ichi Muramatsu, Atsumi Nitt. N-Acetyl Transferase, Shati/Nat8l, in the Dorsal Hippocampus Suppresses Aging-induced Impairment of Cognitive Function in Mice. Neurochemical research. 2022-04-16. PMID:35428956. |
shati/nat8l overexpression in the dorsal hippocampus of mice did not alter the expression of neurotrophic factors or mitochondrial function-related genes, including bdnf or pgc-1α, which are suggested to be downstream genes of shati/nat8l. |
2022-04-16 |
2023-08-13 |
mouse |
| Ayşenur Sümer Coşkun, Hatice Aslı Bedel, Mustafa Munzuroğlu, Narin Derin, Coşkun Ust. Does Resveratrol Prevent Sevoflurane Toxicity in Newborn Rats? Journal of medicinal food. 2022-04-14. PMID:35420459. |
after performing the open field test on the postnatal 41st day, the animals were dissected, and the hippocampal bdnf levels were determined by western blot method. |
2022-04-14 |
2023-08-13 |
rat |
| Ayşenur Sümer Coşkun, Hatice Aslı Bedel, Mustafa Munzuroğlu, Narin Derin, Coşkun Ust. Does Resveratrol Prevent Sevoflurane Toxicity in Newborn Rats? Journal of medicinal food. 2022-04-14. PMID:35420459. |
sevoflurane exposure significantly decreased hippocampal bdnf levels compared with the control group. |
2022-04-14 |
2023-08-13 |
rat |
| Zakieh Torabi, Maede Rezaie, Asieh Aramvash, Mohammad-Ali Nasiri-Khalili, Mohammad Nasehi, Behnaz Abedi, Salar Vasegh. Interaction of lithium and sleep deprivation on memory performance and anxiety-like behavior in male Wistar rats. Behavioural brain research. 2022-04-12. PMID:35413328. |
as a limitation of this research, it was declared that we did not evaluate the function of gsk3-β and bdnf in the brain of rats, especially in the hippocampus. |
2022-04-12 |
2023-08-13 |
rat |