| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hu Zhang, Ji-Ling Liang, Qiu-Yue Wu, Jin-Xiu Li, Ya Liu, Liang-Wen Wu, Jie-Lun Huang, Xiao-Wen Wu, Ming-Hui Wang, Ning Che. Swimming Suppresses Cognitive Decline of HFD-Induced Obese Mice through Reversing Hippocampal Inflammation, Insulin Resistance, and BDNF Level. Nutrients. vol 14. issue 12. 2022-06-24. PMID:35745162. |
swimming suppresses cognitive decline of hfd-induced obese mice through reversing hippocampal inflammation, insulin resistance, and bdnf level. |
2022-06-24 |
2023-08-14 |
mouse |
| Yating Zhang, Xue Bai, Yi Zhang, Shanshan Yao, Yiduo Cui, Lin-Hao You, Peng Yu, Yan-Zhong Chang, Guofen Ga. Hippocampal Iron Accumulation Impairs Synapses and Memory via Suppressing Furin Expression and Downregulating BDNF Maturation. Molecular neurobiology. 2022-06-22. PMID:35732869. |
hippocampal iron accumulation impairs synapses and memory via suppressing furin expression and downregulating bdnf maturation. |
2022-06-22 |
2023-08-14 |
mouse |
| Yating Zhang, Xue Bai, Yi Zhang, Shanshan Yao, Yiduo Cui, Lin-Hao You, Peng Yu, Yan-Zhong Chang, Guofen Ga. Hippocampal Iron Accumulation Impairs Synapses and Memory via Suppressing Furin Expression and Downregulating BDNF Maturation. Molecular neurobiology. 2022-06-22. PMID:35732869. |
regarding the changes of furin-mediated activities caused by hippocampal iron overload, we found that the maturation of brain-derived neurotrophic factor (bdnf) was impeded and the expression levels of synaptogenesis-related proteins were downregulated, leading to cognitive decline. |
2022-06-22 |
2023-08-14 |
mouse |
| Rosamaria Orlando, Roxana Paula Ginerete, Laura Cavalleri, Vincenza Aliperti, Tiziana Imbriglio, Giuseppe Battaglia, Anna Rita Zuena, Ferdinando Nicoletti, Emilio Merlo Pich, Ginetta Coll. Synergic action of L-acetylcarnitine and L-methylfolate in Mouse Models of Stress-Related Disorders and Human iPSC-Derived Dopaminergic Neurons. Frontiers in pharmacology. vol 13. 2022-06-20. PMID:35721218. |
in both stress paradigms, lac and mf acted synergistically in reducing the immobility time in the forced swim test and enhancing bdnf protein levels in the frontal cortex and hippocampus. |
2022-06-20 |
2023-08-14 |
mouse |
| Bongjun Sur, Bombi Le. Myricetin Inhibited Fear and Anxiety-Like Behaviors by HPA Axis Regulation and Activation of the BDNF-ERK Signaling Pathway in Posttraumatic Stress Disorder Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-06-20. PMID:35722162. |
it also increased the reduction in the brain-derived neurotrophic factor (bdnf) and tropomyosin-related kinase b mrna expression and the ratio of p-erk/extracellular signal-regulated kinase (erk) in the hippocampus. |
2022-06-20 |
2023-08-14 |
rat |
| Marco Pagliusi, Daniela Franco, Shannon Cole, Gessynger Morais-Silva, Ramesh Chandra, Megan E Fox, Sergio D Iñiguez, Cesar R Sartori, Mary Kay Lob. The BDNF-TrkB Pathway Acts Through Nucleus Accumbens D2 Expressing Neurons to Mediate Stress Susceptible Outcomes. Frontiers in psychiatry. vol 13. 2022-06-20. PMID:35722560. |
in stress outcomes, bdnf acting in the hippocampus has a stress resilience effect, and, inversely, in the nucleus accumbens (nac), bdnf acts as a stress susceptible molecule. |
2022-06-20 |
2023-08-14 |
mouse |
| Seval Keloglan Musuroglu, Duygu Murat Ozturk, Leyla Sahin, Ozge Selin Cevik, Kenan Cevi. Environmental enrichment as a strategy: attenuates the anxiety and memory impairment in social isolation stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-06-20. PMID:35724417. |
this study was designed to examine how ee affects memory functions, anxiety level, and the expression levels of memory/anxiety-related genes such as nr2a, nr2b, bdnf, and cfos in the hippocampus of socially isolated rats. |
2022-06-20 |
2023-08-14 |
rat |
| Roberto Laureano-Melo, Raoni Conceição Dos-Santos, Rodrigo Rodrigues da Conceição, Janaina Sena de Souza, Claudio da Silva Almeida, Luís Carlos Reis, Bruno Guimarães Marinho, Gisele Giannocco, Ahmed Rg, Wellington da Silva Côrte. Neonatal D-fenfluramine Treatment Promotes Long-Term Behavioral Changes in Adult Mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-06-19. PMID:35718760. |
alternatively, there was a reduction only in the tryptophan hydroxylase (tph2) and bdnf expression in the hippocampus. |
2022-06-19 |
2023-08-14 |
mouse |
| Fabrizio Sanna, Maria Pina Serra, Marianna Boi, Jessica Bratzu, Laura Poddighe, Francesco Sanna, Antonella Carta, Maria Giuseppa Corda, Osvaldo Giorgi, Maria Rosaria Melis, Antonio Argiolas, Marina Quart. Neuroplastic changes in c-Fos, ΔFosB, BDNF, trkB, and Arc expression in the hippocampus of male Roman rats: differential effects of sexual activity. Hippocampus. 2022-06-18. PMID:35716117. |
neuroplastic changes in c-fos, Δfosb, bdnf, trkb, and arc expression in the hippocampus of male roman rats: differential effects of sexual activity. |
2022-06-18 |
2023-08-14 |
rat |
| Fabrizio Sanna, Maria Pina Serra, Marianna Boi, Jessica Bratzu, Laura Poddighe, Francesco Sanna, Antonella Carta, Maria Giuseppa Corda, Osvaldo Giorgi, Maria Rosaria Melis, Antonio Argiolas, Marina Quart. Neuroplastic changes in c-Fos, ΔFosB, BDNF, trkB, and Arc expression in the hippocampus of male Roman rats: differential effects of sexual activity. Hippocampus. 2022-06-18. PMID:35716117. |
sexual activity causes differential changes in the expression of markers of neural activation (c-fos and Δfosb) and neural plasticity (arc and bdnf/trkb), as determined either by western blot (bdnf, trkb, arc, and Δfosb) or immunohistochemistry (bdnf, trkb, arc, and c-fos), in the hippocampus of male roman high (rha) and low avoidance (rla) rats, two psychogenetically selected rat lines that display marked differences in sexual behavior (rha rats exhibit higher sexual motivation and better copulatory performance than rla rats). |
2022-06-18 |
2023-08-14 |
rat |
| Fabrizio Sanna, Maria Pina Serra, Marianna Boi, Jessica Bratzu, Laura Poddighe, Francesco Sanna, Antonella Carta, Maria Giuseppa Corda, Osvaldo Giorgi, Maria Rosaria Melis, Antonio Argiolas, Marina Quart. Neuroplastic changes in c-Fos, ΔFosB, BDNF, trkB, and Arc expression in the hippocampus of male Roman rats: differential effects of sexual activity. Hippocampus. 2022-06-18. PMID:35716117. |
both methods showed (with some differences) that sexual activity modifies the expression levels of these markers in the hippocampus of roman rats depending on: (i) the level of sexual experience, that is, changes were usually more evident in sexually naïve than in experienced rats; (ii) the hippocampal partition, that is, bdnf and arc increased in the dorsal but tended to decrease in the ventral hippocampus; (iii) the marker considered, that is, in sexually experienced animals bdnf, c-fos, and arc levels were similar to those of controls, while Δfosb levels increased; and (iv) the rat line, that is, changes were usually larger in rha than rla rats. |
2022-06-18 |
2023-08-14 |
rat |
| Itsuki Kageyama, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Ryosuke Fujii, Yuki Nouchi, Takuya Wakasugi, Tomohide Sakakibara, Atsushi Teshigawara, Hiroaki Ishikawa, Yohei Shimono, Koji Suzuki, Shuji Hashimoto, Koji Ohash. Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence. PloS one. vol 17. issue 6. 2022-06-17. PMID:35714129. |
we analyzed mrna and protein levels for qpcr and western blotting, respectively, of a hippocampal nf, brain-derived neurotrophic factor (bdnf). |
2022-06-17 |
2023-08-14 |
rat |
| Itsuki Kageyama, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Ryosuke Fujii, Yuki Nouchi, Takuya Wakasugi, Tomohide Sakakibara, Atsushi Teshigawara, Hiroaki Ishikawa, Yohei Shimono, Koji Suzuki, Shuji Hashimoto, Koji Ohash. Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence. PloS one. vol 17. issue 6. 2022-06-17. PMID:35714129. |
hfcs consumption reduced hippocampal bdnf mrna and protein expressions in childhood and adolescence. |
2022-06-17 |
2023-08-14 |
rat |
| Sneha Sagarkar, Nagashree Bhat, Madhura Sapre, Biru Dudhabhate, Dadasaheb M Kokare, Nishikant K Subhedar, Amul J Sakharka. TET1-induced DNA demethylation in dentate gyrus is important for reward conditioning and reinforcement. Molecular neurobiology. 2022-06-15. PMID:35705787. |
the hippocampus of conditioned rats displayed higher mrna levels of ten-eleven translocase 1 (tet1) and brain-derived neurotrophic factor (bdnf) after memory probe trial. |
2022-06-15 |
2023-08-14 |
rat |
| Sneha Sagarkar, Nagashree Bhat, Madhura Sapre, Biru Dudhabhate, Dadasaheb M Kokare, Nishikant K Subhedar, Amul J Sakharka. TET1-induced DNA demethylation in dentate gyrus is important for reward conditioning and reinforcement. Molecular neurobiology. 2022-06-15. PMID:35705787. |
the tet1-induced dna demethylation at the bdnf promoters raised bdnf levels in the hippocampus, thereby setting the stage for reward memory retrieval. |
2022-06-15 |
2023-08-14 |
rat |
| Solange de Souza Stork, Marcos Hübner, Erica Biehl, Lucineia Gainski Danielski, Sandra Bonfante, Larissa Joaquim, Tais Denicol, Thaina Cidreira, Anita Pacheco, Erick Bagio, Everton Lanzzarin, Gabriela Bernades, Mariana Pacheco de Oliveira, Larissa Espindola da Silva, Josiel M Mack, Franciane Bobinski, Gislaine Tezza Rezin, Tatiana Barichello, Emilio Luiz Streck, Fabricia Petronilh. Diabetes Exacerbates Sepsis-Induced Neuroinflammation and Brain Mitochondrial Dysfunction. Inflammation. 2022-06-10. PMID:35689164. |
levels of il-6, il-10, brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), and mitochondrial respiratory chain complexes were evaluated in the hippocampus and prefrontal cortex 24 h after sepsis by cecal ligation and perforation (clp) in wistar rats induced to type 1 diabetes by alloxan (150 mg/kg). |
2022-06-10 |
2023-08-14 |
rat |
| Mohsen Sheykhhasan, Razieh Amini, Sara Soleimani Asl, Massoud Saidijam, Seyed Mahmoud Hashemi, Rezvan Najaf. Neuroprotective effects of coenzyme Q10-loaded exosomes obtained from adipose-derived stem cells in a rat model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-09. PMID:35679720. |
according to the findings of this study, exo+ coq10 enhanced cognition and memory deficiency in alzheimer's disease by boosting bdnf and sox2 levels in the hippocampus. |
2022-06-09 |
2023-08-14 |
rat |
| Martina Stazi, Silvia Zampar, Madeleine Nadolny, Luca Büschgens, Thomas Meyer, Oliver Wirth. Combined long-term enriched environment and caffeine supplementation improve memory function in C57Bl6 mice. European archives of psychiatry and clinical neuroscience. 2022-06-08. PMID:35676374. |
mice housed under ee conditions showed increased gene expression levels of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2022-06-08 |
2023-08-14 |
mouse |
| Asma Batool, Sadia Saleem, Fizza Naqvi, Khwaja Ali Hasan, Faizan Naqvi, Saida Haide. Thymol mitigates cadmium-induced behavioral and cognitive deficits by up-regulating hippocampal BDNF levels in rats. Pakistan journal of pharmaceutical sciences. vol 35. issue 2(Special). 2022-06-07. PMID:35668569. |
thymol mitigates cadmium-induced behavioral and cognitive deficits by up-regulating hippocampal bdnf levels in rats. |
2022-06-07 |
2023-08-14 |
human |
| Asma Batool, Sadia Saleem, Fizza Naqvi, Khwaja Ali Hasan, Faizan Naqvi, Saida Haide. Thymol mitigates cadmium-induced behavioral and cognitive deficits by up-regulating hippocampal BDNF levels in rats. Pakistan journal of pharmaceutical sciences. vol 35. issue 2(Special). 2022-06-07. PMID:35668569. |
brain sample were collected and bdnf was measured in hippocampus. |
2022-06-07 |
2023-08-14 |
human |