Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yuanyuan Ma, Yelong Ji, Li Xu, Zheng Li, Shengjin G. Obesity aggravated hippocampal-dependent cognitive impairment after sleeve gastrectomy in C57/BL6J mice via SIRT1/CREB/BDNF pathway. Experimental brain research. 2022-09-17. PMID:36114835. |
hippocampal expression of sirt1, p-creb, and bdnf in the hds group was significantly lower than that of the hdc group. |
2022-09-17 |
2023-08-14 |
mouse |
Xiao-Jun Wu, Qin-Qin Shu, Bin Wang, Lan Dong, Bin Ha. Acetoacetate Improves Memory in Alzheimer's Mice via Promoting Brain-Derived Neurotrophic Factor and Inhibiting Inflammation. American journal of Alzheimer's disease and other dementias. vol 37. 2022-09-16. PMID:36113018. |
secondarily, acetoacetate stimulated the expression of hippocampal brain-derived neurotrophic factor (bdnf). |
2022-09-16 |
2023-08-14 |
mouse |
Silvia Hoirisch-Clapauc. The Fibrinolytic System in Peripartum Depression. Seminars in thrombosis and hemostasis. 2022-09-16. PMID:36113504. |
brain-derived neurotrophic factor (bdnf), synthesized as a precursor that is activated through cleavage by tissue plasminogen activator and plasmin, influences adult neurogenesis and neuronal plasticity in the hippocampus and prefrontal cortex. |
2022-09-16 |
2023-08-14 |
Not clear |
Martin G Codagnone, Nirit Kara, Anna Ratsika, Brunno Rocha Levone, Marcel van de Wouw, Laura A Tan, Jacobi I Cunningham, Connie Sanchez, John F Cryan, Olivia F O'Lear. Inhibition of FKBP51 induces stress resilience and alters hippocampal neurogenesis. Molecular psychiatry. 2022-09-14. PMID:36104438. |
safit2 increased neurite outgrowth and number of branch points to a greater extent than brain derived neurotrophic factor (bdnf) in primary hippocampal neuronal cultures. |
2022-09-14 |
2023-08-14 |
mouse |
Yuki Tomiga, Yasuki Higaki, Keizo Anzai, Hirokazu Takahash. Behavioral defects and downregulation of hippocampal BDNF and nNOS expression in db/db mice did not improved by chronic TGF-β2 treatment. Frontiers in physiology. vol 13. 2022-09-12. PMID:36091357. |
behavioral defects and downregulation of hippocampal bdnf and nnos expression in db/db mice did not improved by chronic tgf-β2 treatment. |
2022-09-12 |
2023-08-14 |
mouse |
Somaieh Ahmadabady, Mahmoud Hosseini, Mohammad Naser Shafei, Narges Marefati, Hossein Salmani, Sabiheh Amirahmadi, Sakineh Sadat Mortazavi Sani, Farimah Behesht. The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor. Behavioural pharmacology. 2022-09-12. PMID:36094051. |
cur also increased hippocampal synthesis of bdnf in hypothyroid rats. |
2022-09-12 |
2023-08-14 |
rat |
Andrés Prochnik, Adriana L Burgueño, Mara R Rubinstein, María P Marcone, María S Bianchi, María R Gonzalez Murano, Ana M Genaro, Miriam R Wal. Sexual dimorphism modulates metabolic and cognitive alterations under HFD nutrition and chronic stress exposure in mice. Correlation between spatial memory impairment and BDNF mRNA expression in hippocampus and spleen. Neurochemistry international. 2022-09-02. PMID:36055604. |
correlation between spatial memory impairment and bdnf mrna expression in hippocampus and spleen. |
2022-09-02 |
2023-08-14 |
mouse |
Wentong Zhang, Jun Wang, Luanfeng Wang, Renjie Shi, Chuanqi Chu, Zhiling Shi, Pujie Liu, Yitong Li, Xuebo Liu, Zhigang Li. Alternate-day fasting prevents non-alcoholic fatty liver disease and working memory impairment in diet-induced obese mice. The Journal of nutritional biochemistry. 2022-09-01. PMID:36049672. |
moreover, adf improved the working memory and synaptic structure in the dio mice and upregulated psd-95 and bdnf in the hippocampus. |
2022-09-01 |
2023-08-14 |
mouse |
Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
hippocampal bdnf mediated anxiety-like behaviours induced by obesogenic diet withdrawal. |
2022-08-30 |
2023-08-14 |
rat |
Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
obesogenic diets (ods) consumption is associated with anxiety-like behaviour and negative changes in hippocampal bdnf. |
2022-08-30 |
2023-08-14 |
rat |
Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
the present work aimed to assess the relationship between anxiety-like behaviour with hippocampal bdnf in a wtd rodent model. |
2022-08-30 |
2023-08-14 |
rat |
Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
besides increasing anxiety-like behaviours and lowering sociability, the wtd led to an increase in bdnf in the dentate gyrus and the ca1 of the hippocampus. |
2022-08-30 |
2023-08-14 |
rat |
Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
the mediation models analyses suggested that the effect of wtd on anxiety-like behaviour was driven by hippocampal bdnf, this mediation of effect was region-dependent. |
2022-08-30 |
2023-08-14 |
rat |
Tingting Zhou, Suli He, Xin Ye, Zhaolan Wei, Jian Wan, Hongmao Zhang, Shumao Din. Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF. The Science of the total environment. 2022-08-30. PMID:36041608. |
immunohistochemistry in the hippocampus indicated that the level of brain-derived neurotrophic factor (bdnf) in the dg region was significantly increased. |
2022-08-30 |
2023-08-14 |
mouse |
Tingting Zhou, Suli He, Xin Ye, Zhaolan Wei, Jian Wan, Hongmao Zhang, Shumao Din. Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF. The Science of the total environment. 2022-08-30. PMID:36041608. |
the experimental results demonstrated that the mechanism of the combined-exposure injury to neurons in the hippocampus of mice may be that mwcnts with adsorbed dbp can induce the release of bdnf, accelerate the apoptosis of neurons, and reduce the number of nerve cells, which activates microglia, causing neuroinflammation and nervous system toxicity. |
2022-08-30 |
2023-08-14 |
mouse |
Vadim Tseilikman, Andrey Akulov, Oleg Shevelev, Anna Khotskina, Galina Kontsevaya, Mikhail Moshkin, Julia Fedotova, Anton Pashkov, Olga Tseilikman, Eduard Agletdinov, David Tseilikman, Marina Kondashevskaya, Evgenii Zavjalo. Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012411. |
in addition, we evaluated the gene bdnf expression in the hippocampus which is considered to be a main factor of neuroplasticity. |
2022-08-26 |
2023-08-14 |
rat |
Vadim Tseilikman, Andrey Akulov, Oleg Shevelev, Anna Khotskina, Galina Kontsevaya, Mikhail Moshkin, Julia Fedotova, Anton Pashkov, Olga Tseilikman, Eduard Agletdinov, David Tseilikman, Marina Kondashevskaya, Evgenii Zavjalo. Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012411. |
moreover, in the hippocampus of low-anxiety rats compared to the control group and high-anxiety rats, the following changes were observed: (a) a decrease in n-acetyl aspartate levels with a simultaneous increase in phosphoryl ethanol amine levels; (b) an increase in lipid peroxidation levels; (c) a decrease in apparent diffusion coefficient value; (d) an increase in bdnf gene expression. |
2022-08-26 |
2023-08-14 |
rat |
James D Ryan, Nathaniel Tse, Chienchun Huang, Ruirong Yang, Francis S Le. The role of BDNF in mediating the prophylactic effects of (R,S)-ketamine on fear generalization and extinction. Translational psychiatry. vol 12. issue 1. 2022-08-25. PMID:36008382. |
we then used fiber photometry to parse out underlying neural activity and found that in the ventral hippocampus there were significant fear generalization-dependent patterns of activity for wild type and bdnf val66met mice that were altered by prophylactic (r,s)-ketamine treatment. |
2022-08-25 |
2023-08-14 |
mouse |
James D Ryan, Nathaniel Tse, Chienchun Huang, Ruirong Yang, Francis S Le. The role of BDNF in mediating the prophylactic effects of (R,S)-ketamine on fear generalization and extinction. Translational psychiatry. vol 12. issue 1. 2022-08-25. PMID:36008382. |
overall, these findings indicate a role for the ventral hippocampus and bdnf signaling in modulating the mitigating effects of prophylactic (r,s)-ketamine treatment on generalized fear. |
2022-08-25 |
2023-08-14 |
mouse |
Nikita S Persaud, Hannah M Cate. The Epigenetics of Anxiety Pathophysiology: A DNA Methylation and Histone Modification Focused Review. eNeuro. 2022-08-23. PMID:35998298. |
in this review, we summarize and discuss a plethora of dna methylation, histone modification, and associated gene expression differences underscoring the anxiety phenotype.findings we outline include expression changes of various dmnts and changes in histone modifications that affect the hypothalamic pituitary adrenal axis and stress response as well as gaba, glutamate, and bdnf signaling in the pfc, amygdala, hypothalamus, and hippocampus. |
2022-08-23 |
2023-08-14 |
Not clear |