| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenjing Yan, Hulin Zhu, Pengbo Zhang, Ting Sun, Shuai Gong, Guoxiu Sun, Zeqiang Re. Heterotopic 4T1 breast cancer transplantation induces hippocampal inflammation and depressive-like behaviors in mice. Metabolic brain disease. 2022-08-10. PMID:35947291. |
immunohistochemistry studies revealed reduced levels of serotonin, norepinephrine, and bdnf in the hippocampus and serum. |
2022-08-10 |
2023-08-14 |
mouse |
| Suzuka Miura, Eri Oyanagi, Chihiro Watanabe, Hiroki Hamada, Takafumi Aoki, Michael J Kremenik, Hiromi Yan. Acetyl-L-carnitine attenuates Poly I: C- induced sickness behavior in mice. Bioscience, biotechnology, and biochemistry. 2022-08-09. PMID:35945649. |
the gene expression of brain-derived neurotrophic factor (bdnf) in the cerebrum and hippocampus, which is associated with physical activity, was higher in the alc-treated group. |
2022-08-09 |
2023-08-14 |
mouse |
| Nabila E Abdelmeguid, Tasneem M Hammad, Ashraf M Abdel-Moneim, Sherine Abdel Sala. Effect of Epigallocatechin-3-gallate on Stress-Induced Depression in a Mouse Model: Role of Interleukin-1β and Brain-Derived Neurotrophic Factor. Neurochemical research. 2022-08-08. PMID:35939172. |
in conclusion, our study demonstrates that the antidepressive action of egcg involves downregulation of serum il-1β, upregulation of bdnf mrna in the hippocampus, and reduction of ca3 neuronal lesions. |
2022-08-08 |
2023-08-14 |
mouse |
| Xinna Li, Xiaofang Shi, Madaline McPherson, Mary Hager, Gonzalo G Garcia, Richard A Mille. Cap-independent translation of GPLD1 enhances markers of brain health in long-lived mutant and drug-treated mice. Aging cell. 2022-08-05. PMID:35930768. |
these mice also have elevated levels of hippocampal brain-derived neurotrophic factor (bdnf) and of doublecortin (dcx), suggesting a mechanism for maintenance of cognitive function at older ages. |
2022-08-05 |
2023-08-14 |
mouse |
| Mengxi Lu, Xia He, Zhexiao Jiao, Zewen Hu, Zijing Guo, Shiyun Dai, Hui Wang, Dan X. The upregulation of glutamate decarboxylase 67 against hippocampal excitability damage in male fetal rats by prenatal caffeine exposure. Environmental toxicology. 2022-08-02. PMID:35917217. |
these results indicated that pce inhibits the bdnf pathway and mediates the hippocampus's glutamate (glu) excitotoxicity. |
2022-08-02 |
2023-08-14 |
rat |
| Laura Musazzi, Paolo Tornese, Nathalie Sala, Francis S Lee, Maurizio Popoli, Alessandro Ierac. Acute stress induces an aberrant increase of presynaptic release of glutamate and cellular activation in the hippocampus of BDNF Journal of cellular physiology. 2022-07-31. PMID:35908196. |
acute stress induces an aberrant increase of presynaptic release of glutamate and cellular activation in the hippocampus of bdnf stressful life events are considered major risk factors for the development of several psychiatric disorders, though people differentially cope with stress. |
2022-07-31 |
2023-08-14 |
human |
| Tadahiro Numakawa, Haruki Odak. The Role of Neurotrophin Signaling in Age-Related Cognitive Decline and Cognitive Diseases. International journal of molecular sciences. vol 23. issue 14. 2022-07-27. PMID:35887075. |
brain-derived neurotrophic factor (bdnf) and its high affinity receptor trkb are highly expressed in the cortical and hippocampal areas and play an essential role in learning and memory. |
2022-07-27 |
2023-08-14 |
Not clear |
| Soraya Mansouri, Ali-Akbar Salari, Ali Abedi, Parham Mohammadi, Mohammad Aman. Melatonin treatment improves cognitive deficits by altering inflammatory and neurotrophic factors in the hippocampus of obese mice. Physiology & behavior. 2022-07-20. PMID:35858673. |
we measured inflammatory cytokines including tumor necrosis factor (tnf)-α, interferon (ifn)-γ, interleukin (il)-17a, and brain-derived neurotrophic factor (bdnf) in the hippocampus of obese mice. |
2022-07-20 |
2023-08-14 |
mouse |
| Soraya Mansouri, Ali-Akbar Salari, Ali Abedi, Parham Mohammadi, Mohammad Aman. Melatonin treatment improves cognitive deficits by altering inflammatory and neurotrophic factors in the hippocampus of obese mice. Physiology & behavior. 2022-07-20. PMID:35858673. |
our results show that hfd-induced obesity significantly impaired working, spatial and recognition memory by increasing ifn-γ and il-17a and decreasing bdnf levels in the hippocampus of mice. |
2022-07-20 |
2023-08-14 |
mouse |
| Soraya Mansouri, Ali-Akbar Salari, Ali Abedi, Parham Mohammadi, Mohammad Aman. Melatonin treatment improves cognitive deficits by altering inflammatory and neurotrophic factors in the hippocampus of obese mice. Physiology & behavior. 2022-07-20. PMID:35858673. |
on the other hand, melatonin treatment effectively improved all cognitive impairments and reduced tnf-α, ifn-γ, and il-17a and elevated bdnf levels in the hippocampus of obese mice. |
2022-07-20 |
2023-08-14 |
mouse |
| Jing-Yu Qi, Liu-Kun Yang, Xin-Shang Wang, Min Wang, Xu-Bo Li, Ban Feng, Yu-Mei Wu, Shui-Bing Liu, Kun Zhan. Mechanism of CNS regulation by irisin, a multifunctional protein. Brain research bulletin. 2022-07-19. PMID:35850187. |
it has been reported that irisin can cross the blood-brain barrier and increase the expression of a brain-derived neurotrophic factor (bdnf) in the hippocampus, which improves learning and memory. |
2022-07-19 |
2023-08-14 |
Not clear |
| Jonghyuk Park, Jimmy Kim, Toshio Mikam. Exercise hormone irisin prevents physical inactivity-induced cognitive decline in mice. Behavioural brain research. 2022-07-19. PMID:35850397. |
regular exercise also increased hippocampal brain-derived neurotrophic factor (bdnf) expression and brdu-positive cells, alleviating cognitive decline and mental deterioration induced by pi. |
2022-07-19 |
2023-08-14 |
mouse |
| Jonghyuk Park, Jimmy Kim, Toshio Mikam. Exercise hormone irisin prevents physical inactivity-induced cognitive decline in mice. Behavioural brain research. 2022-07-19. PMID:35850397. |
moreover, plasma irisin level was positively correlated with working memory, hippocampal bdnf levels, and hippocampal cell proliferation. |
2022-07-19 |
2023-08-14 |
mouse |
| Christian Berthou, Jean Paul Iliou, Denis Barb. Iron, neuro-bioavailability and depression. EJHaem. vol 3. issue 1. 2022-07-18. PMID:35846210. |
noradrenaline also has impact on neuroplasticity via brain-derived neurotrophic factor (bdnf), which is key for prefrontal and hippocampus neurons playing a role in depression. |
2022-07-18 |
2023-08-14 |
Not clear |
| Tingliang Gong, Zhaoliang Luo, Li Huang, Caixian Xiao, Junlu Yi, Junfeng Yan, Qian Chen, Weihong Li, Wenqiang Ta. Effect and Mechanism of Yisui Fuyongtang (YSFYT) Decoction on Cognitive Function and Synaptic Plasticity in Rats with Vascular Cognitive Impairment. Journal of immunology research. vol 2022. 2022-07-18. PMID:35846430. |
further pathology and protein detection methods were adopted to investigate the action of ysfyt decoction on the neurons in the hippocampus of model rats and the regulation of the brain derived neurotrophic factor (bdnf)-tyrosine protein kinase receptor b (trkb) signaling pathway. |
2022-07-18 |
2023-08-14 |
rat |
| Sarah A Abd El-Aal, Mohamed AbdElrahman, Ahmed M Reda, Hassan Afify, Ghada M Ragab, Amira A El-Gazar, Sherihan Salaheldin Abdelhamid Ibrahi. Galangin Mitigates DOX-induced Cognitive Impairment in Rats: Implication of NOX-1/Nrf-2/HMGB1/TLR4 and TNF-α/MAPKs/RIPK/MLKL/BDNF. Neurotoxicology. 2022-07-17. PMID:35843304. |
in contrast to dox-impaired rats, gal effectively preserved hippocampal neurons, improved cognitive/behavioral functions, and enhanced the expression of the cell repair/growth index and bdnf. |
2022-07-17 |
2023-08-14 |
rat |
| Diego Incontri-Abraham, Felipe J Esparza-Salazar, Antonio Ibarr. Copolymer-1 as a potential therapy for mild cognitive impairment. Brain and cognition. vol 162. 2022-07-16. PMID:35841771. |
in addition to its anti-inflammatory properties, it stimulates brain-derived neurotrophic factor (bdnf) secretion, a neurotrophin involved in neurogenesis and the generation of hippocampal long-term potentials. |
2022-07-16 |
2023-08-14 |
Not clear |
| Lin-Sheng Shi, Chun-Hui Ji, Wen-Qian Tang, Yue Liu, Wei Zhang, Wei Gua. Hippocampal miR-124 participates in the pathogenesis of depression via regulating the expression of BDNF in a Chronic Social Defeat Stress model of depression. Current neurovascular research. 2022-07-15. PMID:35838216. |
hippocampal mir-124 participates in the pathogenesis of depression via regulating the expression of bdnf in a chronic social defeat stress model of depression. |
2022-07-15 |
2023-08-14 |
mouse |
| Lin-Sheng Shi, Chun-Hui Ji, Wen-Qian Tang, Yue Liu, Wei Zhang, Wei Gua. Hippocampal miR-124 participates in the pathogenesis of depression via regulating the expression of BDNF in a Chronic Social Defeat Stress model of depression. Current neurovascular research. 2022-07-15. PMID:35838216. |
conclusion hippocampal mir-124 participated in the pathogenesis of depression by regulating bdnf biosynthesis and was a feasible antidepressant target. |
2022-07-15 |
2023-08-14 |
mouse |
| Evgeniya V Markova, Maria A Knyazheva, Maria A Tikhonova, Tamara G Amstislavskay. Structural and functional characteristics of the hippocampus in depressive-like recipients after transplantation of in vitro caffeine-modulated immune cells. Neuroscience letters. 2022-07-15. PMID:35839995. |
the effects of caffeine-treated immune cells transplantation on neuronal density, production of brain-derived neurotrophic factor (bdnf) and a number of cytokines in the hippocampus of depressive-like syngeneic animals were studied. |
2022-07-15 |
2023-08-14 |
mouse |