| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
obesogenic diets (ods) consumption is associated with anxiety-like behaviour and negative changes in hippocampal bdnf. |
2022-08-30 |
2023-08-14 |
rat |
| Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
the present work aimed to assess the relationship between anxiety-like behaviour with hippocampal bdnf in a wtd rodent model. |
2022-08-30 |
2023-08-14 |
rat |
| Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
besides increasing anxiety-like behaviours and lowering sociability, the wtd led to an increase in bdnf in the dentate gyrus and the ca1 of the hippocampus. |
2022-08-30 |
2023-08-14 |
rat |
| Breno Picin Casagrande, Alessandra Mussi Ribeiro, Luciana Pellegrini Pisani, Debora Estadell. Hippocampal BDNF mediated anxiety-like behaviours induced by obesogenic diet withdrawal. Behavioural brain research. 2022-08-30. PMID:36041572. |
the mediation models analyses suggested that the effect of wtd on anxiety-like behaviour was driven by hippocampal bdnf, this mediation of effect was region-dependent. |
2022-08-30 |
2023-08-14 |
rat |
| Tingting Zhou, Suli He, Xin Ye, Zhaolan Wei, Jian Wan, Hongmao Zhang, Shumao Din. Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF. The Science of the total environment. 2022-08-30. PMID:36041608. |
immunohistochemistry in the hippocampus indicated that the level of brain-derived neurotrophic factor (bdnf) in the dg region was significantly increased. |
2022-08-30 |
2023-08-14 |
mouse |
| Tingting Zhou, Suli He, Xin Ye, Zhaolan Wei, Jian Wan, Hongmao Zhang, Shumao Din. Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF. The Science of the total environment. 2022-08-30. PMID:36041608. |
the experimental results demonstrated that the mechanism of the combined-exposure injury to neurons in the hippocampus of mice may be that mwcnts with adsorbed dbp can induce the release of bdnf, accelerate the apoptosis of neurons, and reduce the number of nerve cells, which activates microglia, causing neuroinflammation and nervous system toxicity. |
2022-08-30 |
2023-08-14 |
mouse |
| Vadim Tseilikman, Andrey Akulov, Oleg Shevelev, Anna Khotskina, Galina Kontsevaya, Mikhail Moshkin, Julia Fedotova, Anton Pashkov, Olga Tseilikman, Eduard Agletdinov, David Tseilikman, Marina Kondashevskaya, Evgenii Zavjalo. Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012411. |
in addition, we evaluated the gene bdnf expression in the hippocampus which is considered to be a main factor of neuroplasticity. |
2022-08-26 |
2023-08-14 |
rat |
| Vadim Tseilikman, Andrey Akulov, Oleg Shevelev, Anna Khotskina, Galina Kontsevaya, Mikhail Moshkin, Julia Fedotova, Anton Pashkov, Olga Tseilikman, Eduard Agletdinov, David Tseilikman, Marina Kondashevskaya, Evgenii Zavjalo. Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012411. |
moreover, in the hippocampus of low-anxiety rats compared to the control group and high-anxiety rats, the following changes were observed: (a) a decrease in n-acetyl aspartate levels with a simultaneous increase in phosphoryl ethanol amine levels; (b) an increase in lipid peroxidation levels; (c) a decrease in apparent diffusion coefficient value; (d) an increase in bdnf gene expression. |
2022-08-26 |
2023-08-14 |
rat |
| James D Ryan, Nathaniel Tse, Chienchun Huang, Ruirong Yang, Francis S Le. The role of BDNF in mediating the prophylactic effects of (R,S)-ketamine on fear generalization and extinction. Translational psychiatry. vol 12. issue 1. 2022-08-25. PMID:36008382. |
we then used fiber photometry to parse out underlying neural activity and found that in the ventral hippocampus there were significant fear generalization-dependent patterns of activity for wild type and bdnf val66met mice that were altered by prophylactic (r,s)-ketamine treatment. |
2022-08-25 |
2023-08-14 |
mouse |
| James D Ryan, Nathaniel Tse, Chienchun Huang, Ruirong Yang, Francis S Le. The role of BDNF in mediating the prophylactic effects of (R,S)-ketamine on fear generalization and extinction. Translational psychiatry. vol 12. issue 1. 2022-08-25. PMID:36008382. |
overall, these findings indicate a role for the ventral hippocampus and bdnf signaling in modulating the mitigating effects of prophylactic (r,s)-ketamine treatment on generalized fear. |
2022-08-25 |
2023-08-14 |
mouse |
| Nikita S Persaud, Hannah M Cate. The Epigenetics of Anxiety Pathophysiology: A DNA Methylation and Histone Modification Focused Review. eNeuro. 2022-08-23. PMID:35998298. |
in this review, we summarize and discuss a plethora of dna methylation, histone modification, and associated gene expression differences underscoring the anxiety phenotype.findings we outline include expression changes of various dmnts and changes in histone modifications that affect the hypothalamic pituitary adrenal axis and stress response as well as gaba, glutamate, and bdnf signaling in the pfc, amygdala, hypothalamus, and hippocampus. |
2022-08-23 |
2023-08-14 |
Not clear |
| Xu Lu, Huijun Liu, Zixuan Cai, Zhichao Hu, Minxiu Ye, Yue Gu, Yue Wang, Dan Wang, Qun Lu, Zhongxia Shen, Xinhua Shen, Chao Huan. ERK1/2-dependent BDNF synthesis and signaling is required for the antidepressant effect of microglia stimulation. Brain, behavior, and immunity. 2022-08-22. PMID:35995236. |
these results suggest that increased bdnf synthesis through activation of erk1/2 caused by a single lps injection and subsequent trkb signaling are required for the antidepressant effect of hippocampal microglial stimulation. |
2022-08-22 |
2023-08-14 |
mouse |
| Camila Espasandín, Sofía Rivero, Laura Bengoa, Karina Cal, Gerardo Romanelli, Juan Claudio Benech, Juan Pablo Damiá. CaMKIV/CREB/BDNF signaling pathway expression in prefrontal cortex, amygdala, hippocampus and hypothalamus in streptozotocin-induced diabetic mice with anxious-like behavior. Experimental brain research. 2022-08-19. PMID:35984483. |
the objective of this study was to determine whether mice with type 1 diabetes (t1dm) induced with streptozotocin show a profile of anxious-type behaviors and alterations in the expression/activity of camkiv, creb, pcreb and bdnf in different regions of the brain (prefrontal cortex, amygdala, hippocampus and hypothalamus) in comparison to non-diabetic mice (ndb). |
2022-08-19 |
2023-08-14 |
mouse |
| Bongjun Sur, Bombi Le. Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder. Journal of natural medicines. 2022-08-18. PMID:35982366. |
it also increased the reduction in the brain-derived neurotrophic factor (bdnf) and tropomyosin-related kinase b (trkb) mrnas expression, and the ratio of p-akt/akt in the hippocampus. |
2022-08-18 |
2023-08-14 |
rat |
| Daria Savitska, Morgan Hess, Dila Calis, Philine Marchetta, Csaba Harasztosi, Stefan Fink, Philipp Eckert, Peter Ruth, Lukas Rüttiger, Marlies Knipper, Wibke Singe. Stress Affects Central Compensation of Neural Responses to Cochlear Synaptopathy in a cGMP-Dependent Way. Frontiers in neuroscience. vol 16. 2022-08-15. PMID:35968392. |
lower central compensation resulted in poorer temporal auditory processing, reduced hippocampal ltp, and decreased recruitment of activity-dependent brain-derived neurotrophic factor (bdnf) expression in hippocampal regions ( |
2022-08-15 |
2023-08-14 |
Not clear |
| Candan Sağlam, İnci Turan, Hale Sayan Özaçma. THE EFFECT OF GLUCAGON LIKE PEPTIDE -1 RECEPTOR AGONIST ON BEHAVIORAL DESPAIR AND ANXIETY-LIKE BEHAVIOR IN OVARIECTOMIZED RATS: MODULATION OF BDNF/CREB, NRF2 AND LIPOCALIN 2. Behavioural brain research. 2022-08-12. PMID:35961539. |
the objective of the present study is to evaluate the effect of glp-1ra, namely liraglutide, on emotional behaviors, and to identify the level of oxidative stress, neuroinflammation, and bdnf signaling in the hippocampus of ovx rats. |
2022-08-12 |
2023-08-14 |
rat |
| Candan Sağlam, İnci Turan, Hale Sayan Özaçma. THE EFFECT OF GLUCAGON LIKE PEPTIDE -1 RECEPTOR AGONIST ON BEHAVIORAL DESPAIR AND ANXIETY-LIKE BEHAVIOR IN OVARIECTOMIZED RATS: MODULATION OF BDNF/CREB, NRF2 AND LIPOCALIN 2. Behavioural brain research. 2022-08-12. PMID:35961539. |
the levels of bdnf, creb, nrf2, and lipocalin 2 in the hippocampal tissue were measured by elisa. |
2022-08-12 |
2023-08-14 |
rat |
| Candan Sağlam, İnci Turan, Hale Sayan Özaçma. THE EFFECT OF GLUCAGON LIKE PEPTIDE -1 RECEPTOR AGONIST ON BEHAVIORAL DESPAIR AND ANXIETY-LIKE BEHAVIOR IN OVARIECTOMIZED RATS: MODULATION OF BDNF/CREB, NRF2 AND LIPOCALIN 2. Behavioural brain research. 2022-08-12. PMID:35961539. |
moreover, bdnf, creb, and nrf2 levels decreased significantly in the hippocampus of ovx rats. |
2022-08-12 |
2023-08-14 |
rat |
| Candan Sağlam, İnci Turan, Hale Sayan Özaçma. THE EFFECT OF GLUCAGON LIKE PEPTIDE -1 RECEPTOR AGONIST ON BEHAVIORAL DESPAIR AND ANXIETY-LIKE BEHAVIOR IN OVARIECTOMIZED RATS: MODULATION OF BDNF/CREB, NRF2 AND LIPOCALIN 2. Behavioural brain research. 2022-08-12. PMID:35961539. |
liraglutide treatment limited the reduction of bdnf and nrf2 levels in the hippocampus, maintaining them at the control levels. |
2022-08-12 |
2023-08-14 |
rat |
| Wenjing Yan, Hulin Zhu, Pengbo Zhang, Ting Sun, Shuai Gong, Guoxiu Sun, Zeqiang Re. Heterotopic 4T1 breast cancer transplantation induces hippocampal inflammation and depressive-like behaviors in mice. Metabolic brain disease. 2022-08-10. PMID:35947291. |
expression levels of monoaminergic system markers, brain-derived neurotrophic factor (bdnf), pro-inflammatory cytokines, and nuclear factor-kappa b (nfκb) in the hippocampus and serum were detected using immunochemistry and western and enzyme-linked immunosorbent assay analysis. |
2022-08-10 |
2023-08-14 |
mouse |