| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Evgeniya V Markova, Maria A Knyazheva, Maria A Tikhonova, Tamara G Amstislavskay. Structural and functional characteristics of the hippocampus in depressive-like recipients after transplantation of in vitro caffeine-modulated immune cells. Neuroscience letters. 2022-07-15. PMID:35839995. |
in depressive-like recipients, an increase in the density of pyramidal neurons in ca1 and ca3 hippocampal regions, accompanied with augmented level of bdnf, decreased levels of pro-inflammatory (il-1β, il-6, inf-γ, and tnf-α) and increased levels of anti-inflammatory (il-10 and il-4) cytokines was found. |
2022-07-15 |
2023-08-14 |
mouse |
| Andra Ionescu-Tucker, Liqi Tong, Nicole C Berchtold, Carl W Cotma. Inhibiting BDNF Signaling Upregulates Hippocampal H3K9me3 in a Manner Dependent On Frontiers in aging. vol 3. 2022-07-13. PMID:35821854. |
inhibiting bdnf signaling upregulates hippocampal h3k9me3 in a manner dependent on histone modifications are key contributors to the cognitive decline that occurs in aging and alzheimer's disease. |
2022-07-13 |
2023-08-14 |
mouse |
| T N Dong, E A Kramár, J H Beardwood, A Al-Shammari, M A Wood, A A Keise. Temporal endurance of exercise-induced benefits on hippocampus-dependent memory and synaptic plasticity in female mice. Neurobiology of learning and memory. 2022-07-10. PMID:35811066. |
however, our assessment of hippocampal bdnf mrna expression following memory retrieval reveals no difference between exercise conditions and control, suggesting that persistent bdnf upregulation may not be required for maintenance of exercise-induced benefits. |
2022-07-10 |
2023-08-14 |
mouse |
| Gyuho Lee, Yunwook Kim, Jung-Hee Jang, Chan Lee, Jaewoo Yoon, Nayoung Ahn, Kijin Ki. Effects of an Exercise Program Combining Aerobic and Resistance Training on Protein Expressions of Neurotrophic Factors in Obese Rats Injected with Beta-Amyloid. International journal of environmental research and public health. vol 19. issue 13. 2022-07-09. PMID:35805580. |
changes in physical fitness, cognitive function, blood levels of beta-amyloid and metabolic factors, and protein expressions of neurotrophic factors related to brain function such as bdnf (brain-derived neurotrophic factor) in the quadriceps femoris, hippocampus, and cerebral cortex were analyzed. |
2022-07-09 |
2023-08-14 |
human |
| Shigeru Katayama, Chizuru Okahata, Masashi Onozato, Takaaki Minami, Masanaga Maeshima, Kazuaki Ogihara, Shinya Yamazaki, Yuta Takahashi, Soichiro Nakamur. Buckwheat Flour and Its Starch Prevent Age-Related Cognitive Decline by Increasing Hippocampal BDNF Production in Senescence-Accelerated Mouse Prone 8 Mice. Nutrients. vol 14. issue 13. 2022-07-09. PMID:35807886. |
buckwheat flour and its starch prevent age-related cognitive decline by increasing hippocampal bdnf production in senescence-accelerated mouse prone 8 mice. |
2022-07-09 |
2023-08-14 |
mouse |
| Saeed Asadzadeh Bayqara, Mohammadreza Aghazadeh Yamchelu, Sheyda Abdolahzadeyadegari, Mona Farhadi, Shabnam Nadjafi, Javad Fahanik Babaei, Nasrin Hossein. 'The effects of a chalcone derivative on memory, hippocampal corticosterone and BDNF levels in adult rats. The International journal of neuroscience. 2022-07-07. PMID:35796038. |
'the effects of a chalcone derivative on memory, hippocampal corticosterone and bdnf levels in adult rats. |
2022-07-07 |
2023-08-14 |
rat |
| Saeed Asadzadeh Bayqara, Mohammadreza Aghazadeh Yamchelu, Sheyda Abdolahzadeyadegari, Mona Farhadi, Shabnam Nadjafi, Javad Fahanik Babaei, Nasrin Hossein. 'The effects of a chalcone derivative on memory, hippocampal corticosterone and BDNF levels in adult rats. The International journal of neuroscience. 2022-07-07. PMID:35796038. |
since chalcones belong to the flavonoid family, the effects of a new synthetic chalcone derivative on memory, chronic stress, and expression of hippocampal bdnf gene were studied. |
2022-07-07 |
2023-08-14 |
rat |
| Saeed Asadzadeh Bayqara, Mohammadreza Aghazadeh Yamchelu, Sheyda Abdolahzadeyadegari, Mona Farhadi, Shabnam Nadjafi, Javad Fahanik Babaei, Nasrin Hossein. 'The effects of a chalcone derivative on memory, hippocampal corticosterone and BDNF levels in adult rats. The International journal of neuroscience. 2022-07-07. PMID:35796038. |
after the behavioral (pa, of, and mwm) tests, the levels of serum corticosterone (cort) and hippocampal brain-derived neurotrophic factor (bdnf) were analyzed. |
2022-07-07 |
2023-08-14 |
rat |
| Saeed Asadzadeh Bayqara, Mohammadreza Aghazadeh Yamchelu, Sheyda Abdolahzadeyadegari, Mona Farhadi, Shabnam Nadjafi, Javad Fahanik Babaei, Nasrin Hossein. 'The effects of a chalcone derivative on memory, hippocampal corticosterone and BDNF levels in adult rats. The International journal of neuroscience. 2022-07-07. PMID:35796038. |
furthermore, a 20 mg/kg ip injection of chalcone markedly attenuated the decrease of hippocampal bdnf. |
2022-07-07 |
2023-08-14 |
rat |
| Muhammad S Aldhshan, Tooru M Mizun. Effect of environmental enrichment on aggression and the expression of brain-derived neurotrophic factor transcript variants in group-housed male mice. Behavioural brain research. 2022-07-07. PMID:35798208. |
ee increased levels of bdnf mrna variant i (bdnf i) in the amygdala while it reduced levels of bdnf i in the hypothalamus, hippocampus, prefrontal cortex, parietal cortex, and brainstem. |
2022-07-07 |
2023-08-14 |
mouse |
| Liu Xianchu, Peng Huan, Liu Kang, Deng Beiwang, Liu Min. Protective effect of rutin against diabetes-associated cognitive decline in rats. Pakistan journal of pharmaceutical sciences. vol 35. issue 3. 2022-07-06. PMID:35791475. |
in hippocampus, rut markedly inhibited ache, gfap mda, tnf-a and il-1β levels and augmented chat and bdnf, sod, cat, gsh, nrf-2 and ho-1 levels. |
2022-07-06 |
2023-08-14 |
rat |
| Laura Boi, Sabrina Petralla, Barbara Monti, Giuseppe Talani, Enrico Sanna, Maria Giuseppina Pisu, Giulia Calderisi, Elisabetta Maciocco, Mariangela Serra, Alessandra Concas, Patrizia Porc. Chronic treatment with hormonal contraceptives alters hippocampal BDNF and histone H3 post-translational modifications but not learning and memory in female rats. Hormones and behavior. vol 144. 2022-07-05. PMID:35785712. |
chronic treatment with hormonal contraceptives alters hippocampal bdnf and histone h3 post-translational modifications but not learning and memory in female rats. |
2022-07-05 |
2023-08-14 |
rat |
| Laura Boi, Sabrina Petralla, Barbara Monti, Giuseppe Talani, Enrico Sanna, Maria Giuseppina Pisu, Giulia Calderisi, Elisabetta Maciocco, Mariangela Serra, Alessandra Concas, Patrizia Porc. Chronic treatment with hormonal contraceptives alters hippocampal BDNF and histone H3 post-translational modifications but not learning and memory in female rats. Hormones and behavior. vol 144. 2022-07-05. PMID:35785712. |
decreased hippocampal brain-derived neurotrophic factor (bdnf) levels and altered histone h3 post-translational modifications (ptms) were observed 14 days after discontinuation from chronic ee-lng treatment. |
2022-07-05 |
2023-08-14 |
rat |
| Laura Boi, Sabrina Petralla, Barbara Monti, Giuseppe Talani, Enrico Sanna, Maria Giuseppina Pisu, Giulia Calderisi, Elisabetta Maciocco, Mariangela Serra, Alessandra Concas, Patrizia Porc. Chronic treatment with hormonal contraceptives alters hippocampal BDNF and histone H3 post-translational modifications but not learning and memory in female rats. Hormones and behavior. vol 144. 2022-07-05. PMID:35785712. |
these results provide the first evidence of hippocampal epigenetic changes induced by hormonal contraceptives and complement previous studies on the neurobiological actions of hormonal contraceptives; the finding that effects of chronic ee-lng treatment on bdnf content and histone ptms are observed 14 days after drug discontinuation warrants further investigation to better understand the implications of such long-term consequences for women's health. |
2022-07-05 |
2023-08-14 |
rat |
| Ya-Jing Zhu, Jun-Juan Fan, Fang-Yi Wu, Ming Zhang, Ao-Qi Song, Yong Li, Yan-Kun Li, Wen-Ning W. Aging Promotes Chronic Stress-Induced Depressive-Like Behavior by Activating NLRP1 Inflammasome-Driven Inflammatory Signaling in Mice. Inflammation. 2022-07-02. PMID:35779196. |
moreover, aged mice exhibited lower hippocampal bdnf levels compared to young mice. |
2022-07-02 |
2023-08-14 |
mouse |
| Ya-Jing Zhu, Jun-Juan Fan, Fang-Yi Wu, Ming Zhang, Ao-Qi Song, Yong Li, Yan-Kun Li, Wen-Ning W. Aging Promotes Chronic Stress-Induced Depressive-Like Behavior by Activating NLRP1 Inflammasome-Driven Inflammatory Signaling in Mice. Inflammation. 2022-07-02. PMID:35779196. |
hippocampal nlrp1a knockdown reduced the levels of pro-inflammatory cytokines and the expression of cxcl1/cxcr2, restored bdnf levels, and alleviated chronic stress-induced depressive-like behaviors in aged mice. |
2022-07-02 |
2023-08-14 |
mouse |
| Tessa J Helman, John P Headrick, Jason N Peart, Nicolas J C Stapelber. Central and cardiac stress resiliences consistently linked to integrated immuno-neuroendocrine responses across stress models in male mice. The European journal of neuroscience. 2022-06-28. PMID:35763309. |
highly integrated expression of hpa axis, neuro-inflammatory, bdnf, monoamine, gaba, cannabinoid and opioid signalling genes was confirmed across conditions, and consistent/potentially causal correlations identified for: i) locomotor activity (noradrenaline, ghrelin; fc crhr1, tnfrsf1b, il33, nfkb1, maoa, gabra1; hippocampal il33); ii) thigmotaxis (adrenaline, leptin); iii) anxiety-like behaviour (adrenaline, leptin; fc tnfrsf1a; hippocampal il33); iv) depressive-like behaviour (ghrelin; fc/hippocampal s100a8); and v) cardiac stress-resistance (noradrenaline, leptin; fc il33, tnfrsf1b, htr1a, gabra1, gabrg2; hippocampal il33, tnfrsf1a, maoa, drd2). |
2022-06-28 |
2023-08-14 |
mouse |
| Salvatore Saieva, Giulio Taglialatel. Near-infrared light reduces glia activation and modulates neuroinflammation in the brains of diet-induced obese mice. Scientific reports. vol 12. issue 1. 2022-06-27. PMID:35761012. |
lastly, hippocampal levels of the neurotrophic factor bdnf were increased in nir-treated hfd mice, compared to untreated hfd mice. |
2022-06-27 |
2023-08-14 |
mouse |
| Marika Cordaro, Ramona D'Amico, Roberta Fusco, Alessio Filippo Peritore, Tiziana Genovese, Livia Interdonato, Gianluca Franco, Alessia Arangia, Enrico Gugliandolo, Rosalia Crupi, Rosalba Siracusa, Rosanna Di Paola, Salvatore Cuzzocrea, Daniela Impellizzer. Discovering the Effects of Fisetin on NF-κB/NLRP-3/NRF-2 Molecular Pathways in a Mouse Model of Vascular Dementia Induced by Repeated Bilateral Carotid Occlusion. Biomedicines. vol 10. issue 6. 2022-06-24. PMID:35740470. |
here, we found that vad caused brain injury, lipid peroxidation, and neuronal death in the hippocampus, as well as astrocyte and microglial activation, and reduced bdnf neurotrophic factor expression together with behavioral alterations. |
2022-06-24 |
2023-08-14 |
mouse |
| Farid Farhani, Shahnaz Shahrbanian, Mohammad Auais, Amir Hossein Ahmadi Hekmatikar, Katsuhiko Suzuk. Effects of Aerobic Training on Brain Plasticity in Patients with Mild Cognitive Impairment: A Systematic Review of Randomized Controlled Trials. Brain sciences. vol 12. issue 6. 2022-06-24. PMID:35741616. |
twelve studies with medium to high quality were included, of which five studies focused on brain-derived neurotrophic factor (four articles reported elevation and one article reported no changes in bdnf levels following the aerobic exercise), two studies focused on brain structures (both reported increases in hippocampus volume following the aerobic exercise), and five studies focused on brain activity (four articles reported positive changes, and one article reported no changes in brain activity following the aerobic exercise). |
2022-06-24 |
2023-08-14 |
Not clear |