| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mario E Lloret-Torres, Roxsana N Ayala-Pagan, Freddyson J Martínez-Rivera, Pedro Bonilla, Jennifer L Barreto-Estrad. Hippocampal and amygdalar increased BDNF expression in the extinction of opioid-induced place preference. IBRO neuroscience reports. 2022-10-24. PMID:36275846. |
drug conditioning and extinction sessions were followed by western blots for bdnf in the hippocampus (hpc), amygdala (amy) and vs/nac. |
2022-10-24 |
2023-08-14 |
human |
| Nasrin Hashemi-Firouzi, Simin Afshar, Sara Soleimani Asl, Alireza Samzadeh-Kermani, Bahareh Gholamigeravand, Kimia Amiri, Mahsa Majidi, Siamak Shahid. The effects of polyvinyl alcohol-coated selenium nanoparticles on memory impairment in rats. Metabolic brain disease. 2022-10-22. PMID:36271966. |
the expression of hippocampal brain-derived neurotrophic factor (bdnf) and stress oxidative markers (mda and tac), and the number of amyloid-beta (aβ) plaques were assessed using elisa kits, biochemical methods, and congo red staining, respectively. |
2022-10-22 |
2023-08-14 |
rat |
| Yu Zhang, Linhu Du, Jinhua Yan, Qianxiang Bai, Qiao Niu, Yiqun Mo, Qunwei Zhang, Jisheng Ni. Prenatal benzo[a]pyrene exposure impairs hippocampal synaptic plasticity and cognitive function in SD rat offspring during adolescence and adulthood via HDAC2-mediated histone deacetylation. Ecotoxicology and environmental safety. vol 246. 2022-10-20. PMID:36265406. |
the mrna expression of bdnf, psd-95, and syp in offspring hippocampus were detected by qrt-pcr, and the protein expression of bdnf, psd-95, syp, hdac2, ach3k9, and ach3k14 were measured by western blotting or immunohistochemistry. |
2022-10-20 |
2023-08-14 |
rat |
| Yu Zhang, Linhu Du, Jinhua Yan, Qianxiang Bai, Qiao Niu, Yiqun Mo, Qunwei Zhang, Jisheng Ni. Prenatal benzo[a]pyrene exposure impairs hippocampal synaptic plasticity and cognitive function in SD rat offspring during adolescence and adulthood via HDAC2-mediated histone deacetylation. Ecotoxicology and environmental safety. vol 246. 2022-10-20. PMID:36265406. |
the expression of hdac2 protein was significantly upregulated, while ach3k9, ach3k14, bdnf, psd-95, and syp protein levels were significantly downregulated in the hippocampus of b[a]p- exposed rats. |
2022-10-20 |
2023-08-14 |
rat |
| Yu Zhang, Linhu Du, Jinhua Yan, Qianxiang Bai, Qiao Niu, Yiqun Mo, Qunwei Zhang, Jisheng Ni. Prenatal benzo[a]pyrene exposure impairs hippocampal synaptic plasticity and cognitive function in SD rat offspring during adolescence and adulthood via HDAC2-mediated histone deacetylation. Ecotoxicology and environmental safety. vol 246. 2022-10-20. PMID:36265406. |
in addition, chip results showed that prenatal b[a]p exposure markedly decreased the level of ach3k9 and ach3k14 in the promoter region of bdnf and psd-95 gene in the hippocampus of pnd 45 and pnd 75 offspring. |
2022-10-20 |
2023-08-14 |
rat |
| Wen Zhang, Meng-Meng Ge, Long-Qing Zhang, Xiao-Man Yuan, Si-Yi Han, Anne Manyande, Yu-Ke Tian, Xue-Bi Tia. nDysfunction of the BDNF-TrkB signaling pathway contributes to learning and memory impairments induced by neuroinflammation in mice. Neuroscience. 2022-10-20. PMID:36265757. |
in addition, lps reduced the protein levels of bdnf, p-trkb, bcl-2, p-erk1/2, p-camk2, p-creb and p-glur1 and increased the expression of bax in the hippocampus and medial prefrontal cortex regions. |
2022-10-20 |
2023-08-14 |
mouse |
| Allison N Pullin, Victoria S Farrar, Jason W Loxterkamp, Claire T Jones, Rebecca M Calisi, Kristina Horback, Pamela J Lein, Maja M Makago. Providing height to pullets does not influence hippocampal dendritic morphology or brain-derived neurotrophic factor at the end of the rearing period. Poultry science. vol 101. issue 12. 2022-10-17. PMID:36252500. |
overall, providing height during rearing did not affect dendritic morphology or bdnf at 16 wk of age, but other metrics in the hippocampus or other brain regions warrant further investigation. |
2022-10-17 |
2023-08-14 |
Not clear |
| Hunter Franks, Ruishan Wang, Mingqi Li, Bin Wang, Ashton Wildmann, Tyler Ortyl, Shannon O'Brien, Deborah Young, Francesca-Fang Liao, Kazuko Sakat. Heat shock factor HSF1 regulates BDNF gene promoters upon acute stress in the hippocampus, together with pCREB. Journal of neurochemistry. 2022-10-13. PMID:36227087. |
heat shock factor hsf1 regulates bdnf gene promoters upon acute stress in the hippocampus, together with pcreb. |
2022-10-13 |
2023-08-14 |
mouse |
| Hunter Franks, Ruishan Wang, Mingqi Li, Bin Wang, Ashton Wildmann, Tyler Ortyl, Shannon O'Brien, Deborah Young, Francesca-Fang Liao, Kazuko Sakat. Heat shock factor HSF1 regulates BDNF gene promoters upon acute stress in the hippocampus, together with pCREB. Journal of neurochemistry. 2022-10-13. PMID:36227087. |
the results of immunohistochemistry and chromatin immunoprecipitation quantitative pcr (chip-qpcr) showed that administration of kainic acid (a glutamate receptor agonist inducing excitotoxity) to young adult mice induced hsf1 nuclear translocation and its binding to multiple bdnf promoters in the hippocampus. |
2022-10-13 |
2023-08-14 |
mouse |
| Hunter Franks, Ruishan Wang, Mingqi Li, Bin Wang, Ashton Wildmann, Tyler Ortyl, Shannon O'Brien, Deborah Young, Francesca-Fang Liao, Kazuko Sakat. Heat shock factor HSF1 regulates BDNF gene promoters upon acute stress in the hippocampus, together with pCREB. Journal of neurochemistry. 2022-10-13. PMID:36227087. |
taken together, these results suggest that hsf1 promoter-specific control of bdnf gene regulation plays an important role in neuronal protection and plasticity in the hippocampus in response to acute stress, possibly interplaying with pcreb. |
2022-10-13 |
2023-08-14 |
mouse |
| Chen Hong, Zhi Wang, Si-Li Zheng, Wen-Jun Hu, Shu-Na Wang, Yan Zhao, Chao-Yu Mia. Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice. Acta pharmacologica Sinica. 2022-10-13. PMID:36229598. |
metrnl regulates cognitive dysfunction and hippocampal bdnf levels in d-galactose-induced aging mice. |
2022-10-13 |
2023-08-14 |
mouse |
| Chen Hong, Zhi Wang, Si-Li Zheng, Wen-Jun Hu, Shu-Na Wang, Yan Zhao, Chao-Yu Mia. Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice. Acta pharmacologica Sinica. 2022-10-13. PMID:36229598. |
furthermore, metrnl knockout significantly reduced hippocampal bdnf, trkb, and glial fibrillary acidic protein (gfap) levels in the d-gal-induced aging mice. |
2022-10-13 |
2023-08-14 |
mouse |
| Chen Hong, Zhi Wang, Si-Li Zheng, Wen-Jun Hu, Shu-Na Wang, Yan Zhao, Chao-Yu Mia. Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice. Acta pharmacologica Sinica. 2022-10-13. PMID:36229598. |
in the d-gal-induced aging cell model in vitro, metrnl levels in the hippocampal astrocytes were significantly increased, and metrnl knockdown and overexpression regulated the bdnf levels in primary hippocampal astrocytes rather than in neurons. |
2022-10-13 |
2023-08-14 |
mouse |
| Chen Hong, Zhi Wang, Si-Li Zheng, Wen-Jun Hu, Shu-Na Wang, Yan Zhao, Chao-Yu Mia. Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice. Acta pharmacologica Sinica. 2022-10-13. PMID:36229598. |
we conclude that metrnl regulates cognitive functions and hippocampal bdnf levels during aging process. |
2022-10-13 |
2023-08-14 |
mouse |
| Mychael V Lourenco, Guilherme B de Freitas, Ícaro Raony, Sergio T Ferreira, Fernanda G De Felic. Irisin stimulates protective signaling pathways in rat hippocampal neurons. Frontiers in cellular neuroscience. vol 16. 2022-10-03. PMID:36187295. |
we demonstrate that adenoviral-mediated expression of irisin promotes extracellular brain derived neurotrophic factor (bdnf) accumulation in hippocampal cultures. |
2022-10-03 |
2023-08-14 |
mouse |
| Luis Octavio Aguirre López, José Ricardo Cuéllar Pérez, Anne Santerre, Yolanda Salinas Moreno, Yosajandy Hernández De Anda, Jacinto Bañuelos Pined. Effect of consumption of blue maize tortilla on anxiety-like behaviour, learning, memory and hippocampal BDNF expression in a chronic stress model in rats. Nutritional neuroscience. 2022-09-29. PMID:36173025. |
effect of consumption of blue maize tortilla on anxiety-like behaviour, learning, memory and hippocampal bdnf expression in a chronic stress model in rats. |
2022-09-29 |
2023-08-14 |
rat |
| Xiaoju Wang, Peng Xia, Jiulong Song, Ting Yang, Changjun Yu, Kai Cheng, Anliang Chen, Xueping L. Cranial electrotherapy stimulation alleviates depression-like behavior of post-stroke depression rats by upregulating GPX4-mediated BDNF expression. Behavioural brain research. 2022-09-18. PMID:36116735. |
the mrna and protein expressions of gpx4 and bdnf in the hippocampus were detected by qrt-pcr, western blot and immunohistochemical analysis.the degeneration and necrosis of hippocampal neurons, the depression-like behavior were severer and the expression of bdnf in the hippocampus were decreased in psd rats than those in mcao and control groups. |
2022-09-18 |
2023-08-14 |
rat |
| Xiaoju Wang, Peng Xia, Jiulong Song, Ting Yang, Changjun Yu, Kai Cheng, Anliang Chen, Xueping L. Cranial electrotherapy stimulation alleviates depression-like behavior of post-stroke depression rats by upregulating GPX4-mediated BDNF expression. Behavioural brain research. 2022-09-18. PMID:36116735. |
ces promoted the hippocampal neuron repair, alleviated the depression-like behavior and increased the expression of bdnf in psd rats. |
2022-09-18 |
2023-08-14 |
rat |
| Xiaoju Wang, Peng Xia, Jiulong Song, Ting Yang, Changjun Yu, Kai Cheng, Anliang Chen, Xueping L. Cranial electrotherapy stimulation alleviates depression-like behavior of post-stroke depression rats by upregulating GPX4-mediated BDNF expression. Behavioural brain research. 2022-09-18. PMID:36116735. |
conclusion: ces improves depression-like behavior of psd rats through upregulation of gpx4-mediated bdnf expression in the hippocampus. |
2022-09-18 |
2023-08-14 |
rat |
| Yuanyuan Ma, Yelong Ji, Li Xu, Zheng Li, Shengjin G. Obesity aggravated hippocampal-dependent cognitive impairment after sleeve gastrectomy in C57/BL6J mice via SIRT1/CREB/BDNF pathway. Experimental brain research. 2022-09-17. PMID:36114835. |
expression of sirtuin1 (sirt1), phosphorylated camp-responsive element binding protein (p-creb), creb and brain-derived neurotrophic factor (bdnf) in the hippocampus were measured. |
2022-09-17 |
2023-08-14 |
mouse |