| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Saeed Naghibi, Mohammad Shariatzadeh Joneydi, Ali Barzegari, Azam Davoodabadi, Amirhossein Ebrahimi, Elham Eghdami, Narges Fahimpour, Mahmood Ghorbani, Ehsan Mohammadikia, Mozhgan Rostami, Ali-Akbar Salar. Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with sporadic Alzheimer-like disease. Physiology & behavior. vol 241. 2021-10-27. PMID:34536437. |
besides, treadmill exercise alone decreased depression-related behaviours and increased hippocampal bdnf in females but not males. |
2021-10-27 |
2023-08-13 |
rat |
| Saeed Naghibi, Mohammad Shariatzadeh Joneydi, Ali Barzegari, Azam Davoodabadi, Amirhossein Ebrahimi, Elham Eghdami, Narges Fahimpour, Mahmood Ghorbani, Ehsan Mohammadikia, Mozhgan Rostami, Ali-Akbar Salar. Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with sporadic Alzheimer-like disease. Physiology & behavior. vol 241. 2021-10-27. PMID:34536437. |
we also found that treadmill exercise decreased depression-related behaviours and tnf-α in the hippocampus and prefrontal cortex, and increased il-10 in the prefrontal cortex and bdnf in the hippocampus of female ald-induced rats. |
2021-10-27 |
2023-08-13 |
rat |
| Xianshengjie Lang, Na Zhao, Qiang He, Xun Li, Xuejiao Li, Chuanning Sun, Xianliang Zhan. Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM. Brain research bulletin. vol 165. 2021-10-26. PMID:32987101. |
this study investigated the effects of treadmill exercise on the hippocampal inflammatory response and bdnf expression in a t2dm mice model. |
2021-10-26 |
2023-08-13 |
mouse |
| Xianshengjie Lang, Na Zhao, Qiang He, Xun Li, Xuejiao Li, Chuanning Sun, Xianliang Zhan. Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM. Brain research bulletin. vol 165. 2021-10-26. PMID:32987101. |
we found that treadmill exercise for 8 weeks can significantly improve the cognitive dysfunction, alleviate activation of proinflammatory microglia m1 (iba1 labeling) in the hippocampus of t2dm mice, and reduce the levels of proinflammatory factors il-1β, il-6, tnf-α, increase the expression levels of anti-inflammatory factors il-10, tgf-β1, and promote the release of bdnf. |
2021-10-26 |
2023-08-13 |
mouse |
| Xianshengjie Lang, Na Zhao, Qiang He, Xun Li, Xuejiao Li, Chuanning Sun, Xianliang Zhan. Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM. Brain research bulletin. vol 165. 2021-10-26. PMID:32987101. |
our results showed that long-term moderate intensity treadmill exercise can alleviate inflammatory response in the hippocampus and increase bdnf expression in t2dm mice by activating sirt1. |
2021-10-26 |
2023-08-13 |
mouse |
| Zahra Fatahi, Arman Zeinaddini-Meymand, Saeideh Karimi-Haghighi, Amir Haghparast, Fariba Khodagholi, Abbas Haghparas. BDNF and p-GSK3β in the hippocampus mediate the impairment of delay-based decision making in morphine-dependent rats. Neuroreport. vol 31. issue 17. 2021-10-26. PMID:33075004. |
bdnf and p-gsk3β in the hippocampus mediate the impairment of delay-based decision making in morphine-dependent rats. |
2021-10-26 |
2023-08-13 |
rat |
| Zahra Fatahi, Arman Zeinaddini-Meymand, Saeideh Karimi-Haghighi, Amir Haghparast, Fariba Khodagholi, Abbas Haghparas. BDNF and p-GSK3β in the hippocampus mediate the impairment of delay-based decision making in morphine-dependent rats. Neuroreport. vol 31. issue 17. 2021-10-26. PMID:33075004. |
the present study aimed to evaluate the influences of morphine dependency and its withdrawal on delay-based decision making and the bdnf, p-gsk3β, and p-creb levels during the decision making in the hippocampus. |
2021-10-26 |
2023-08-13 |
rat |
| Zahra Fatahi, Arman Zeinaddini-Meymand, Saeideh Karimi-Haghighi, Amir Haghparast, Fariba Khodagholi, Abbas Haghparas. BDNF and p-GSK3β in the hippocampus mediate the impairment of delay-based decision making in morphine-dependent rats. Neuroreport. vol 31. issue 17. 2021-10-26. PMID:33075004. |
after behavioral tests, bdnf level, p-gsk3β/gsk3β ratio, and p-creb/creb ratio in the hippocampus measured by western blot analysis. |
2021-10-26 |
2023-08-13 |
rat |
| Zahra Fatahi, Arman Zeinaddini-Meymand, Saeideh Karimi-Haghighi, Amir Haghparast, Fariba Khodagholi, Abbas Haghparas. BDNF and p-GSK3β in the hippocampus mediate the impairment of delay-based decision making in morphine-dependent rats. Neuroreport. vol 31. issue 17. 2021-10-26. PMID:33075004. |
the gathered data showed that level of bdnf enhanced while p-gsk3β/gsk3β ratio and p-creb/creb ratio in the hippocampus did not change during delay-based decision making. |
2021-10-26 |
2023-08-13 |
rat |
| Zahra Fatahi, Arman Zeinaddini-Meymand, Saeideh Karimi-Haghighi, Amir Haghparast, Fariba Khodagholi, Abbas Haghparas. BDNF and p-GSK3β in the hippocampus mediate the impairment of delay-based decision making in morphine-dependent rats. Neuroreport. vol 31. issue 17. 2021-10-26. PMID:33075004. |
the data declared that bdnf in the hippocampus has a critical role in delay-based decision making. |
2021-10-26 |
2023-08-13 |
rat |
| Junlong Li, Pingya He, Jian Zhang, Ning L. Orcinol glucoside improves the depressive-like behaviors of perimenopausal depression mice through modulating activity of hypothalamic-pituitary-adrenal/ovary axis and activating BDNF- TrkB-CREB signaling pathway. Phytotherapy research : PTR. vol 35. issue 10. 2021-10-26. PMID:34382261. |
moreover, og up-regulated the protein expression of bdnf, trkb, and phosphorylation level of creb and erk1/2 in hippocampus. |
2021-10-26 |
2023-08-13 |
mouse |
| Tomasz Antoni Guzel, Katarzyna Mech, Marek Wroński, Katarzyna Gerkowicz, Agata Bednarczyk, Weronika Adamczyk, Monika Radecka, Maciej Słodkowsk. Brain-derived neurotrophic factor in gastroenterology oncology - short review of current literature. Annals of agricultural and environmental medicine : AAEM. vol 28. issue 3. 2021-10-26. PMID:34558255. |
the hippocampal concentration of bdnf is believed to play an important role in learning and memory, it has a protective role in neurodegeneration and stress responses. |
2021-10-26 |
2023-08-13 |
Not clear |
| Hooman Bozorgi, Thomas Budde, Maryam Nankal. Antidepressant-like and memory-enhancing effects of the N-type calcium channel blocker ziconotide in rats. Behavioural brain research. vol 390. 2021-10-25. PMID:32428635. |
hippocampal bdnf levels were significantly increased in rats receiving long-term i.c.v. |
2021-10-25 |
2023-08-13 |
rat |
| Osamu Nakagawasai, Kotaro Yamada, Kohei Takahashi, Takayo Odaira, Wakana Sakuma, Daisuke Ishizawa, Naruya Takahashi, Kentaro Onuma, Chikako Hozumi, Wataru Nemoto, Koichi Tan-N. Liver hydrolysate prevents depressive-like behavior in an animal model of colitis: Involvement of hippocampal neurogenesis via the AMPK/BDNF pathway. Behavioural brain research. vol 390. 2021-10-25. PMID:32434062. |
hippocampal expression of ampk, brain-derived neurotrophic factor (bdnf), doublecortin, and neuronal nuclear antigen proteins was assessed by western blotting. |
2021-10-25 |
2023-08-13 |
mouse |
| Osamu Nakagawasai, Kotaro Yamada, Kohei Takahashi, Takayo Odaira, Wakana Sakuma, Daisuke Ishizawa, Naruya Takahashi, Kentaro Onuma, Chikako Hozumi, Wataru Nemoto, Koichi Tan-N. Liver hydrolysate prevents depressive-like behavior in an animal model of colitis: Involvement of hippocampal neurogenesis via the AMPK/BDNF pathway. Behavioural brain research. vol 390. 2021-10-25. PMID:32434062. |
dss-treated mice showed enhanced hippocampal expression of p-ampk and bdnf after administration of lh. |
2021-10-25 |
2023-08-13 |
mouse |
| Mola Mohammadi, Homa Manaheji, Nader Maghsoudi, Samira Danyali, Mansoureh Baniasadi, Jalal Zaringhala. Microglia dependent BDNF and proBDNF can impair spatial memory performance during persistent inflammatory pain. Behavioural brain research. vol 390. 2021-10-25. PMID:32442548. |
also, pro-brain-derived neurotrophic factor (bdnf)/bdnf ratio, caspase3, and receptor-interacting protein kinase 3 (rip3) levels increased in the rats' hippocampus following induction of persistent inflammatory pain. |
2021-10-25 |
2023-08-13 |
rat |
| Andressa Radiske, Maria Carolina Gonzalez, Diana A Nôga, Janine I Rossato, Lia R M Bevilaqua, Martín Cammarot. mTOR inhibition impairs extinction memory reconsolidation. Learning & memory (Cold Spring Harbor, N.Y.). vol 28. issue 1. 2021-10-25. PMID:33323495. |
fear-motivated avoidance extinction memory is prone to hippocampal brain-derived neurotrophic factor (bdnf)-dependent reconsolidation upon recall. |
2021-10-25 |
2023-08-13 |
Not clear |
| Andressa Radiske, Maria Carolina Gonzalez, Diana A Nôga, Janine I Rossato, Lia R M Bevilaqua, Martín Cammarot. mTOR inhibition impairs extinction memory reconsolidation. Learning & memory (Cold Spring Harbor, N.Y.). vol 28. issue 1. 2021-10-25. PMID:33323495. |
importantly, coadministration of recombinant bdnf impedes the behavioral effect of hippocampal mtor inhibition. |
2021-10-25 |
2023-08-13 |
Not clear |
| Yefeng Yang, Malgorzata Lagisz, Yong Zhi Foo, Daniel W A Noble, Hamza Anwer, Shinichi Nakagaw. Beneficial intergenerational effects of exercise on brain and cognition: a multilevel meta-analysis of mean and variance. Biological reviews of the Cambridge Philosophical Society. vol 96. issue 4. 2021-10-25. PMID:33783115. |
mechanistically, exercise significantly upregulated brain-derived neurotrophic factor (bdnf) by 28.9%, vascular endothelial growth factor (vegf) by 35.8%, and significantly decreased hippocampal dna methylation by 3.5%, suggesting that brain growth factor cascades and epigenetic modifications can moderate the transmission of parental exercise effects. |
2021-10-25 |
2023-08-13 |
Not clear |
| Chong Li, Tian Wang, Na Jiang, Pengfei Yu, Yuan DU, Rutong Ren, Fenghua F. Steady and fluctuant methods of inhibition of acetylcholinesterase differentially regulate neurotrophic factors in the hippocampus of juvenile mice. Experimental and therapeutic medicine. vol 3. issue 2. 2021-10-21. PMID:22969880. |
these findings indicate that steady and fluctuant methods of inhibition of ache have different effects on the levels of bdnf and ngf in the hippocampus. |
2021-10-21 |
2023-08-12 |
mouse |