| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaolan Xie, Zhiwen Shen, Chuwen Hu, Kun Zhang, Mingyan Guo, Fei Wang, Kai Qi. Dexmedetomidine Ameliorates Postoperative Cognitive Dysfunction in Aged Mice. Neurochemical research. vol 46. issue 9. 2021-11-03. PMID:34159456. |
furthermore, dex decreased mda levels, enhanced sod activity, modulated cdk5 activity and increased bdnf expression in the hippocampus. |
2021-11-03 |
2023-08-13 |
mouse |
| Jian-Feng Fan, Zhen-Hui Tang, Shi-Yi Wang, Si Lei, Bo Zhang, Shao-Wen Tia. Ketamine enhances novel object recognition memory reconsolidation via the BDNF/TrkB pathway in mice. Physiology & behavior. vol 242. 2021-11-03. PMID:34673052. |
however, this blockage had no significant effect on the ketamine-induced hippocampal bdnf level increase. |
2021-11-03 |
2023-08-13 |
mouse |
| Jian-Feng Fan, Zhen-Hui Tang, Shi-Yi Wang, Si Lei, Bo Zhang, Shao-Wen Tia. Ketamine enhances novel object recognition memory reconsolidation via the BDNF/TrkB pathway in mice. Physiology & behavior. vol 242. 2021-11-03. PMID:34673052. |
in conclusion, acute low-dose ketamine administration improves nor memory reconsolidation by increasing hippocampal bdnf levels and subsequent bdnf binding to the trkb receptor. |
2021-11-03 |
2023-08-13 |
mouse |
| Jili Zhao, Jinyu Ren, Shuang Liu, Yanan Gong, Ping Meng, Haitao Tan, Yonggang Che. Repeated exposure to sevoflurane in neonatal rats impairs cognition in adulthood via the PKA-CREB-BDNF signaling pathway. Experimental and therapeutic medicine. vol 22. issue 6. 2021-11-02. PMID:34721684. |
hippocampal brain-derived neurotrophic factor (bdnf) levels were measured by elisa. |
2021-11-02 |
2023-08-13 |
rat |
| Jili Zhao, Jinyu Ren, Shuang Liu, Yanan Gong, Ping Meng, Haitao Tan, Yonggang Che. Repeated exposure to sevoflurane in neonatal rats impairs cognition in adulthood via the PKA-CREB-BDNF signaling pathway. Experimental and therapeutic medicine. vol 22. issue 6. 2021-11-02. PMID:34721684. |
the protein expression of protein kinase a (pka), camp response element binding protein (creb), phosphorylated-creb (p-creb) and bdnf in hippocampus were assessed by western blotting. |
2021-11-02 |
2023-08-13 |
rat |
| Jili Zhao, Jinyu Ren, Shuang Liu, Yanan Gong, Ping Meng, Haitao Tan, Yonggang Che. Repeated exposure to sevoflurane in neonatal rats impairs cognition in adulthood via the PKA-CREB-BDNF signaling pathway. Experimental and therapeutic medicine. vol 22. issue 6. 2021-11-02. PMID:34721684. |
furthermore, compared with the control group, neonatal exposure to sev reduced the number of neurons and the concentration of bdnf in the hippocampus, a brain region important for learning and memory. |
2021-11-02 |
2023-08-13 |
rat |
| Tih-Shih Lee, Alexander Y Li, Amedeo Rapuano, John Mantis, Tore Eid, Thomas N Seyfried, Nihal C de Laneroll. Gene expression in the epileptic (EL) mouse hippocampus. Neurobiology of disease. vol 147. 2021-11-01. PMID:33153970. |
the increased expression of bdnf along with immediate early gene expression (fosb, junb, erg4, nr4a1, nr4a2, fbxo3) and the down regulation of gabrd, dbp and malat1 it is hypothesized may contribute to the hyperexcitability of the hippocampal neurons in this model. |
2021-11-01 |
2023-08-13 |
mouse |
| Jeremy S Lum, Katrina M Bird, Jennifer Wilkie, Samuel J Millard, Sachie Pallimulla, Kelly A Newell, Ian M Wrigh. Prenatal methadone exposure impairs adolescent cognition and GABAergic neurodevelopment in a novel rat model of maternal methadone treatment. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33571606. |
immunoblots of the adolescent prefrontal cortex and hippocampus showed methadone-exposed offspring displayed reduced levels of mature bdnf, in addition to the gabaergic proteins, gad67 and parvalbumin, in a sex- and brain region-specific fashion. |
2021-11-01 |
2023-08-13 |
rat |
| Greg L West, Kyoko Konishi, Kathleen MacDonald, Anjie Ni, Ridha Joober, Veronique D Bohbo. The BDNF val66met polymorphism is associated with decreased use of landmarks and decreased fMRI activity in the hippocampus during virtual navigation. The European journal of neuroscience. vol 54. issue 7. 2021-11-01. PMID:34467592. |
the bdnf val66met polymorphism is associated with decreased use of landmarks and decreased fmri activity in the hippocampus during virtual navigation. |
2021-11-01 |
2023-08-13 |
human |
| Greg L West, Kyoko Konishi, Kathleen MacDonald, Anjie Ni, Ridha Joober, Veronique D Bohbo. The BDNF val66met polymorphism is associated with decreased use of landmarks and decreased fMRI activity in the hippocampus during virtual navigation. The European journal of neuroscience. vol 54. issue 7. 2021-11-01. PMID:34467592. |
the val66met polymorphism of the brain-derived neurotrophic factor (bdnf) gene leads to decreased secretion of bdnf in the brain, including the hippocampus. |
2021-11-01 |
2023-08-13 |
human |
| Greg L West, Kyoko Konishi, Kathleen MacDonald, Anjie Ni, Ridha Joober, Veronique D Bohbo. The BDNF val66met polymorphism is associated with decreased use of landmarks and decreased fMRI activity in the hippocampus during virtual navigation. The European journal of neuroscience. vol 54. issue 7. 2021-11-01. PMID:34467592. |
additionally, bdnf val/val individuals had more fmri activity in the hippocampus compared with bdnf met carriers during performance on the navigation task. |
2021-11-01 |
2023-08-13 |
human |
| Stephen R Edwards, Nemat Khan, Elizabeth J Coulson, Maree T Smit. Comparative studies of glial fibrillary acidic protein and brain-derived neurotrophic factor expression in two transgenic mouse models of Alzheimer's disease. Clinical and experimental pharmacology & physiology. vol 47. issue 10. 2021-10-29. PMID:32542833. |
we compared the expression of gfap, bdnf, and its precursor probdnf in the dorsal hippocampus of two transgenic ad mouse models. |
2021-10-29 |
2023-08-13 |
mouse |
| Feng Tai, Che Wang, Xin Deng, Ruojin Li, Zimeng Guo, Haiying Quan, Song L. Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice. Brain research bulletin. vol 164. 2021-10-29. PMID:32877716. |
the hippocampal levels of insulin-like growth factor-1 (igf-1) and brain derived neurotrophic factor (bdnf) were further detected using elisa. |
2021-10-29 |
2023-08-13 |
mouse |
| Feng Tai, Che Wang, Xin Deng, Ruojin Li, Zimeng Guo, Haiying Quan, Song L. Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice. Brain research bulletin. vol 164. 2021-10-29. PMID:32877716. |
in addition, 2m-sd exposure increased ne and da, decreased 5-ht and gaba, and reduced igf-1 and bdnf levels in mouse hippocampus. |
2021-10-29 |
2023-08-13 |
mouse |
| Wellington de Almeida, Heloísa Deola Confortim, Bruna Ferrary Deniz, Patrícia Maidana Miguel, Milene Cardoso Vieira, Loise Bronauth, Adriana Souza Dos Santos, Karine Bertoldi, Ionara Rodrigues Siqueira, Lenir Orlandi Pereir. Acrobatic exercise recovers object recognition memory impairment in hypoxic-ischemic rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 1. 2021-10-28. PMID:33135304. |
bdnf and synaptophysin neuroplasticity markers indicate plastic alterations in the hippocampus and striatum, with maintenance of synaptophysin despite the reduction of total volume tissue, besides, hippocampal hi-induced ipsilateral bdnf increased, and striatum contralateral bdnf decreased were noted. |
2021-10-28 |
2023-08-13 |
rat |
| Janine Karina Hideko Alfenas Horita, Maria Carolina Machado da Silva, Carolina Zaniboni Ferrari, Erica Leandro Marciano Vieira, Fabricio A Moreira, Antônio Carlos Pinheiro de Oliveira, Helton José Rei. Evaluation of Brain Cytokines and the Level of Brain-Derived Neurotrophic Factor in an Inflammatory Model of Depression. Neuroimmunomodulation. vol 27. issue 2. 2021-10-28. PMID:33176302. |
inflammatory processes are likely involved in its pathophysiology, but the underlying mechanisms have remained uncertain.here, we used the model of systemic lipopolysaccharide (lps) injection to test the hypothesis that depressive-like behaviors occur along with changes in the levels of cytokines and brain-derived neurotrophic factor (bdnf) in the hippocampus (hc), prefrontal cortex (pfc), and hypothalamus (ht), and can be prevented by dexamethasone administration. |
2021-10-28 |
2023-08-13 |
Not clear |
| Markus Petermann, Golo Kronenberg, Valentina Mosienko, Michael Bader, Natalia Alenina, Rainer Hellweg, Friederike Klempi. Alterations in BDNF Protein Concentrations in the Hippocampus do not Explain the Pro-Neurogenic Effect of Citalopram on Adult Neurogenesis. Pharmacopsychiatry. vol 54. issue 3. 2021-10-28. PMID:33197939. |
alterations in bdnf protein concentrations in the hippocampus do not explain the pro-neurogenic effect of citalopram on adult neurogenesis. |
2021-10-28 |
2023-08-13 |
Not clear |
| Björn H Schott, Golo Kronenberg, Ulrike Schmidt, Henning P Düsedau, Stefanie Ehrentraut, Olga Geisel, Oliver von Bohlen Und Halbach, Peter Gass, Ildiko Rita Dunay, Rainer Hellwe. Robustly High Hippocampal BDNF levels under Acute Stress in Mice Lacking the Full-length p75 Neurotrophin Receptor. Pharmacopsychiatry. vol 54. issue 5. 2021-10-28. PMID:33592642. |
robustly high hippocampal bdnf levels under acute stress in mice lacking the full-length p75 neurotrophin receptor. |
2021-10-28 |
2023-08-13 |
mouse |
| Björn H Schott, Golo Kronenberg, Ulrike Schmidt, Henning P Düsedau, Stefanie Ehrentraut, Olga Geisel, Oliver von Bohlen Und Halbach, Peter Gass, Ildiko Rita Dunay, Rainer Hellwe. Robustly High Hippocampal BDNF levels under Acute Stress in Mice Lacking the Full-length p75 Neurotrophin Receptor. Pharmacopsychiatry. vol 54. issue 5. 2021-10-28. PMID:33592642. |
acute and chronic stress have been associated with suppression of hippocampal bdnf expression and impaired hippocampal plasticity. |
2021-10-28 |
2023-08-13 |
mouse |
| Björn H Schott, Golo Kronenberg, Ulrike Schmidt, Henning P Düsedau, Stefanie Ehrentraut, Olga Geisel, Oliver von Bohlen Und Halbach, Peter Gass, Ildiko Rita Dunay, Rainer Hellwe. Robustly High Hippocampal BDNF levels under Acute Stress in Mice Lacking the Full-length p75 Neurotrophin Receptor. Pharmacopsychiatry. vol 54. issue 5. 2021-10-28. PMID:33592642. |
we hypothesized that p75ntr might be involved in the hippocampal stress response, in particular in stress-induced bdnf suppression, which might be accompanied by increased neuroinflammation. |
2021-10-28 |
2023-08-13 |
mouse |