| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenbo Xu, Xiaoxiao Yao, Fangyi Zhao, Haisheng Zhao, Ziqian Cheng, Wei Yang, Ranji Cui, Songbai Xu, Bingjin L. Changes in Hippocampal Plasticity in Depression and Therapeutic Approaches Influencing These Changes. Neural plasticity. vol 2020. 2021-10-14. PMID:33293948. |
in this review, we summarize the latest research, focusing on changes in the plasticity of hippocampal neurons and glial cells in depression and the role of bdnf in the changes in hippocampal plasticity in depression, as well as caloric restriction and mitochondrial plasticity. |
2021-10-14 |
2023-08-13 |
human |
| Lorena Henn, Natália C Zanta, Carlos Eduardo N Girardi, Deborah Sucheck. Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33063280. |
chronic escitalopram treatment does not alter the effects of neonatal stress on hippocampal bdnf levels, 5-ht early life stress is considered a risk factor for the development of long-term psychiatric disorders. |
2021-10-13 |
2023-08-13 |
Not clear |
| Lorena Henn, Natália C Zanta, Carlos Eduardo N Girardi, Deborah Sucheck. Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33063280. |
the goal of the present study was to examine the effects of a chronic treatment with escitalopram (esc) on the hippocampal levels of bdnf and neuropeptide y (npy), expression of serotonin type 1a receptor (5-ht |
2021-10-13 |
2023-08-13 |
Not clear |
| Machhindra Garad, Elke Edelmann, Volkmar Leßman. Long-term depression at hippocampal mossy fiber-CA3 synapses involves BDNF but is not mediated by p75NTR signaling. Scientific reports. vol 11. issue 1. 2021-10-13. PMID:33879805. |
long-term depression at hippocampal mossy fiber-ca3 synapses involves bdnf but is not mediated by p75ntr signaling. |
2021-10-13 |
2023-08-13 |
Not clear |
| Machhindra Garad, Elke Edelmann, Volkmar Leßman. Long-term depression at hippocampal mossy fiber-CA3 synapses involves BDNF but is not mediated by p75NTR signaling. Scientific reports. vol 11. issue 1. 2021-10-13. PMID:33879805. |
while most experimental evidence for this bdnf dependence of synaptic plasticity in the hippocampus was derived from schaffer collateral (sc)-ca1 synapses, much less is known about the mechanisms of synaptic plasticity, in particular ltd, at hippocampal mossy fiber (mf) synapses onto ca3 neurons. |
2021-10-13 |
2023-08-13 |
Not clear |
| Yuan Li, Yufeng Jia, Dongdong Wang, Xiao Zhuang, Yan Li, Chun Guo, Hongxia Chu, Faliang Zhu, Jianing Wang, Xiaoyan Wang, Qun Wang, Wei Zhao, Yongyu Shi, Wanjun Chen, Lining Zhan. Programmed cell death 4 as an endogenous suppressor of BDNF translation is involved in stress-induced depression. Molecular psychiatry. vol 26. issue 6. 2021-10-11. PMID:32203159. |
chronic restraint stress (crs) up-regulated pdcd4 expression in hippocampus via decreasing mtorc1-mediated proteasomes degradation pathway, which resulted in the reduction of bdnf protein expression. |
2021-10-11 |
2023-08-13 |
mouse |
| Zhen Kang, Haimin Ye, Tao Chen, Peng Zhan. Effect of Electroacupuncture at Siguan Acupoints on Expression of BDNF and TrkB Proteins in the Hippocampus of Post-Stroke Depression Rats. Journal of molecular neuroscience : MN. vol 71. issue 10. 2021-10-11. PMID:34041688. |
effect of electroacupuncture at siguan acupoints on expression of bdnf and trkb proteins in the hippocampus of post-stroke depression rats. |
2021-10-11 |
2023-08-13 |
rat |
| Zhen Kang, Haimin Ye, Tao Chen, Peng Zhan. Effect of Electroacupuncture at Siguan Acupoints on Expression of BDNF and TrkB Proteins in the Hippocampus of Post-Stroke Depression Rats. Journal of molecular neuroscience : MN. vol 71. issue 10. 2021-10-11. PMID:34041688. |
to study the effect of electroacupuncture at the siguan acupoints on the expression of hippocampal brain-derived neurotrophic factor (bdnf) and tyrosine receptor kinase b (trkb) in post-stroke depression (psd) rats, in order to explore its possible mechanism fifty specific pathogen-free (spf)-grade adult male sprague-dawley (sd) rats were randomly divided into a blank group, stroke group, psd group, siguan acupoint group and fluoxetine group according to the random number method. |
2021-10-11 |
2023-08-13 |
rat |
| Zhen Kang, Haimin Ye, Tao Chen, Peng Zhan. Correction to: Effect of Electroacupuncture at Siguan Acupoints on Expression of BDNF and TrkB Proteins in the Hippocampus of Post-Stroke Depression Rats. Journal of molecular neuroscience : MN. vol 71. issue 10. 2021-10-11. PMID:34184198. |
correction to: effect of electroacupuncture at siguan acupoints on expression of bdnf and trkb proteins in the hippocampus of post-stroke depression rats. |
2021-10-11 |
2023-08-13 |
rat |
| Moshe Hagar, Gersner Roman, Okun Eitan, Barnea-Ygael Noam, Zangen Abrham, Sredni Benjami. A Tellurium-Based Small Immunomodulatory Molecule Ameliorates Depression-Like Behavior in Two Distinct Rat Models. Neuromolecular medicine. vol 22. issue 3. 2021-10-07. PMID:32638207. |
3 to attain insight into the mechanism we knocked down bdnf in the hippocampus, and demonstrated that the beneficial effect of as101 was abrogated. |
2021-10-07 |
2023-08-13 |
rat |
| Xuncui Wang, Wen Xu, Hejuntao Chen, Weizu Li, Weiping Li, Guoqi Zh. Astragaloside IV prevents Aβ Brain research. vol 1747. 2021-10-07. PMID:32739157. |
in this study, we found that amyloid β protein fragment 1-42 oligomers (aβo) suppressed bdnf and pparγ expression, and inhibited tyrosine receptor kinase b (trkb) phosphorylation in cultured hippocampal neurons; these changes were ameliorated by treatment with as-iv. |
2021-10-07 |
2023-08-13 |
Not clear |
| Xuncui Wang, Wen Xu, Hejuntao Chen, Weizu Li, Weiping Li, Guoqi Zh. Astragaloside IV prevents Aβ Brain research. vol 1747. 2021-10-07. PMID:32739157. |
moreover, as-iv suppressed the aβo-induced reduction in bdnf by promoting pparγ activation in the hippocampus. |
2021-10-07 |
2023-08-13 |
Not clear |
| Mayur Kale, Nitin Nimje, Manish M Aglawe, Milind Umekar, Brijesh Taksande, Nandkishor Kotagal. Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats. Brain research. vol 1747. 2021-10-07. PMID:32758481. |
it was associated with increased expression of pro-inflammatory cytokines like il-6 and tnf-α, and reduced bdnf immunocontent in the hippocampal tissues. |
2021-10-07 |
2023-08-13 |
rat |
| Reza Sardar, Zahra Zandieh, Zeinab Namjoo, Mansoureh Soleimani, Reza Shirazi, Javad Ham. Laterality and sex differences in the expression of brain-derived neurotrophic factor in developing rat hippocampus. Metabolic brain disease. vol 36. issue 1. 2021-10-07. PMID:32975719. |
bdnf is strongly expressed in the hippocampus, where has been associated with memory consolidation, learning, and cognition. |
2021-10-07 |
2023-08-13 |
rat |
| Reza Sardar, Zahra Zandieh, Zeinab Namjoo, Mansoureh Soleimani, Reza Shirazi, Javad Ham. Laterality and sex differences in the expression of brain-derived neurotrophic factor in developing rat hippocampus. Metabolic brain disease. vol 36. issue 1. 2021-10-07. PMID:32975719. |
in this study, real-time pcr, immunohistochemistry, and stereology were used to evaluate the gender differences and left-right asymmetries in the expression of bdnf in the developing rat hippocampus during the neurogenesis-active period, at postnatal days p0, p7 and p14. |
2021-10-07 |
2023-08-13 |
rat |
| Reza Sardar, Zahra Zandieh, Zeinab Namjoo, Mansoureh Soleimani, Reza Shirazi, Javad Ham. Laterality and sex differences in the expression of brain-derived neurotrophic factor in developing rat hippocampus. Metabolic brain disease. vol 36. issue 1. 2021-10-07. PMID:32975719. |
at the same time, there were significant differences in the hippocampal expression of bdnf between males and females (p ≤ 0.05 each). |
2021-10-07 |
2023-08-13 |
rat |
| Reza Sardar, Zahra Zandieh, Zeinab Namjoo, Mansoureh Soleimani, Reza Shirazi, Javad Ham. Laterality and sex differences in the expression of brain-derived neurotrophic factor in developing rat hippocampus. Metabolic brain disease. vol 36. issue 1. 2021-10-07. PMID:32975719. |
no important differences in the number of bdnf expressing neurons in different subregions of right/left hippocampus were observed between male and female animals at p0 and p7 (p > 0.05). |
2021-10-07 |
2023-08-13 |
rat |
| Reza Sardar, Zahra Zandieh, Zeinab Namjoo, Mansoureh Soleimani, Reza Shirazi, Javad Ham. Laterality and sex differences in the expression of brain-derived neurotrophic factor in developing rat hippocampus. Metabolic brain disease. vol 36. issue 1. 2021-10-07. PMID:32975719. |
furthermore, the highest numerical density of bdnf positive cells was detected in the both sides hippocampal ca |
2021-10-07 |
2023-08-13 |
rat |
| Rafael Tamborena Malheiros, Helena Oliveira Delgado, Daniel Tassinari Felber, Scheila Iria Kraus, Adair Roberto Soares Dos Santos, Vanusa Manfredini, Morgana Duarte da Silv. Mood disorders are associated with the reduction of brain derived neurotrophic factor in the hypocampus in rats submitted to the hipercaloric diet. Metabolic brain disease. vol 36. issue 1. 2021-10-07. PMID:33025299. |
here, we investigated the effects of a hypercaloric diet on depression- and anxiety-like behaviors in young rats along with concomitant changes in bdnf expression levels in the hippocampus. |
2021-10-07 |
2023-08-13 |
rat |
| Rafael Tamborena Malheiros, Helena Oliveira Delgado, Daniel Tassinari Felber, Scheila Iria Kraus, Adair Roberto Soares Dos Santos, Vanusa Manfredini, Morgana Duarte da Silv. Mood disorders are associated with the reduction of brain derived neurotrophic factor in the hypocampus in rats submitted to the hipercaloric diet. Metabolic brain disease. vol 36. issue 1. 2021-10-07. PMID:33025299. |
changes in mood disposition were evaluated using forced swim test and the elevated plus-maze, whereas hippocampal bdnf expression levels were quantified by elisa. |
2021-10-07 |
2023-08-13 |
rat |