| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shangyan Gao, Xueling Zhang, Hui Xu, Dongjin Miao, Jiaoni Qian, Zhonghua Wu, Weihua Sh. Promoting the hippocampal PPARα expression participates in the antidepressant mechanism of reboxetine, a selective norepinephrine reuptake inhibitor. Behavioural brain research. vol 416. 2021-10-05. PMID:34416301. |
our results showed that repeated reboxetine treatment markedly restored the decreasing effects of csds on the expression of hippocampal pparα, brain-derived neurotrophic factor (bdnf) and phosphorylated camp response element binding protein (pcreb). |
2021-10-05 |
2023-08-13 |
Not clear |
| Luciana Taschetto Vey, Higor Zuquetto Rosa, Raquel Cristine Silva Barcelos, Verônica Tironi Dias, Maria Izabel Ugalde Marques da Rocha, Marilise Escobar Burge. Neonatal handling increases neurogenesis, BDNF and GR in the hippocampus favoring memory acquisition in rats. Brain research. vol 1745. 2021-10-04. PMID:32505752. |
neonatal handling increases neurogenesis, bdnf and gr in the hippocampus favoring memory acquisition in rats. |
2021-10-04 |
2023-08-13 |
rat |
| Luciana Taschetto Vey, Higor Zuquetto Rosa, Raquel Cristine Silva Barcelos, Verônica Tironi Dias, Maria Izabel Ugalde Marques da Rocha, Marilise Escobar Burge. Neonatal handling increases neurogenesis, BDNF and GR in the hippocampus favoring memory acquisition in rats. Brain research. vol 1745. 2021-10-04. PMID:32505752. |
animals exposed to nh showed: i) increased levels of probdnf and brain-derived neurotrophic factor (bdnf); ii) increased memory performance; iii) decreased lipid peroxidation (lp) in plasma and hippocampus; iv) increased antioxidant defenses; v) increased glucocorticoids receptor (gr) levels. |
2021-10-04 |
2023-08-13 |
rat |
| Wakana Sakuma, Osamu Nakagawasai, Wataru Nemoto, Takayo Odaira, Takumi Ogawa, Kiminori Ohta, Yasuyuki Endo, Koichi Tan-N. Antidepressant effect of BE360, a new selective estrogen receptor modulator, activated via CREB/BDNF, Bcl-2 signaling pathways in ovariectomized mice. Behavioural brain research. vol 393. 2021-10-04. PMID:32535181. |
be360 treatment in ovx + stress-exposed mice increased p-creb, bdnf, and bcl-2 expressions in the hippocampus. |
2021-10-04 |
2023-08-13 |
mouse |
| Cinthia R Correa, Claudia Schena, Samantha C Lopes, Rui D Prediger, E L Silva, Débora K R Venske, L C Ribeiro, J D Moreir. Combined effects of caloric restriction and fish oil attenuated anti-depressant and anxiolytic-like effects of fish oil: association with hippocampal BDNF concentrations. Behavioural brain research. vol 393. 2021-10-04. PMID:32561388. |
combined effects of caloric restriction and fish oil attenuated anti-depressant and anxiolytic-like effects of fish oil: association with hippocampal bdnf concentrations. |
2021-10-04 |
2023-08-13 |
rat |
| Cinthia R Correa, Claudia Schena, Samantha C Lopes, Rui D Prediger, E L Silva, Débora K R Venske, L C Ribeiro, J D Moreir. Combined effects of caloric restriction and fish oil attenuated anti-depressant and anxiolytic-like effects of fish oil: association with hippocampal BDNF concentrations. Behavioural brain research. vol 393. 2021-10-04. PMID:32561388. |
here, we investigate the synergic effects of both therapeutic approaches combined (cr + fo) on behavior (memory, anxiety-like behavior, antidepressant-like behavior), as well as its association with hippocampal brain-derived neurotrophic factor (bdnf) concentrations. |
2021-10-04 |
2023-08-13 |
rat |
| Cinthia R Correa, Claudia Schena, Samantha C Lopes, Rui D Prediger, E L Silva, Débora K R Venske, L C Ribeiro, J D Moreir. Combined effects of caloric restriction and fish oil attenuated anti-depressant and anxiolytic-like effects of fish oil: association with hippocampal BDNF concentrations. Behavioural brain research. vol 393. 2021-10-04. PMID:32561388. |
after 12 weeks of dietary treatment, behavioural analysis set was conducted, and hippocampal bdnf concentrations were measured. |
2021-10-04 |
2023-08-13 |
rat |
| Cinthia R Correa, Claudia Schena, Samantha C Lopes, Rui D Prediger, E L Silva, Débora K R Venske, L C Ribeiro, J D Moreir. Combined effects of caloric restriction and fish oil attenuated anti-depressant and anxiolytic-like effects of fish oil: association with hippocampal BDNF concentrations. Behavioural brain research. vol 393. 2021-10-04. PMID:32561388. |
there was a positive association between the number of entries in the platform quadrant in the mwm and hippocampal bdnf concentrations (β = 0.39; r² = 0.15; p = 0.042) and an inverse association between forced swim immobility time and bdnf concentrations (β = -0.39; r² = 0.15; p = 0.041). |
2021-10-04 |
2023-08-13 |
rat |
| Cinthia R Correa, Claudia Schena, Samantha C Lopes, Rui D Prediger, E L Silva, Débora K R Venske, L C Ribeiro, J D Moreir. Combined effects of caloric restriction and fish oil attenuated anti-depressant and anxiolytic-like effects of fish oil: association with hippocampal BDNF concentrations. Behavioural brain research. vol 393. 2021-10-04. PMID:32561388. |
synergic effects of interventions attenuated fo-related behavioral responses and bdnf concentrations and probably reduced hippocampal neuroplasticity. |
2021-10-04 |
2023-08-13 |
rat |
| Majid Motaghinejad, Roya Mashayekh, Manijeh Motevalian, Sepideh Safar. The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences. Fundamental & clinical pharmacology. vol 35. issue 1. 2021-10-04. PMID:32579730. |
hippocampal neurodegenerative and histological parameters as well as cyclic amp response element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) levels were assessed. |
2021-10-04 |
2023-08-13 |
human |
| Majid Motaghinejad, Roya Mashayekh, Manijeh Motevalian, Sepideh Safar. The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences. Fundamental & clinical pharmacology. vol 35. issue 1. 2021-10-04. PMID:32579730. |
additionally, alcohol administration boosted lipid peroxidation and levels of glutathione in oxidized form (gssg), tumor necrosis factor alpha (tnf-α), interleukin 1 beta (il-1β), and bax protein, while decreased reducing type of glutathione (gsh), bcl-2 protein, phosphorylated creb, and bdnf levels in rat hippocampus. |
2021-10-04 |
2023-08-13 |
human |
| Majid Motaghinejad, Roya Mashayekh, Manijeh Motevalian, Sepideh Safar. The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences. Fundamental & clinical pharmacology. vol 35. issue 1. 2021-10-04. PMID:32579730. |
in comparison, minocycline attenuated alcohol-induced neurodegeneration; elevating expression levels of p-creb and bdnf and inhibited alcohol induced histopathological changes in both dentate gyrus (dg) and ca1 of hippocampus. |
2021-10-04 |
2023-08-13 |
human |
| Farimah Beheshti, Hamid Reza Akbari, Yousef Baghcheghi, Fatemeh Mansouritorghabeh, Sakineh Sadat Mortazavi Sani, Mahmoud Hossein. Beneficial effects of angiotensin converting enzyme inhibition on scopolamine-induced learning and memory impairment in rats, the roles of brain-derived neurotrophic factor, nitric oxide and neuroinflammation. Clinical and experimental hypertension (New York, N.Y. : 1993). vol 43. issue 6. 2021-10-04. PMID:33724113. |
in this study, the effects of ras inhibitor captopril (capto) on hippocampal bdnf, interleukin -6 (il-6), oxidative stress indicators, and nitric oxide (no) in scopolamine (sco)-induced memory impairment in rats were examined. |
2021-10-04 |
2023-08-13 |
rat |
| Blanca Marin Bosch, Aurélien Bringard, Maria G Logrieco, Estelle Lauer, Nathalie Imobersteg, Aurélien Thomas, Guido Ferretti, Sophie Schwartz, Kinga Iglo. A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34257382. |
regular physical exercise enhances memory functions, synaptic plasticity in the hippocampus, and brain derived neurotrophic factor (bdnf) levels. |
2021-10-04 |
2023-08-13 |
human |
| Blanca Marin Bosch, Aurélien Bringard, Maria G Logrieco, Estelle Lauer, Nathalie Imobersteg, Aurélien Thomas, Guido Ferretti, Sophie Schwartz, Kinga Iglo. A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34257382. |
likewise, short periods of exercise, or acute exercise, benefit hippocampal plasticity in rodents, via increased endocannabinoids (especially anandamide, aea) and bdnf release. |
2021-10-04 |
2023-08-13 |
human |
| Blanca Marin Bosch, Aurélien Bringard, Maria G Logrieco, Estelle Lauer, Nathalie Imobersteg, Aurélien Thomas, Guido Ferretti, Sophie Schwartz, Kinga Iglo. A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34257382. |
memory after moderate intensity exercise correlated with exercise-induced increases in both aea and bndf levels: while aea was associated with hippocampal activity during memory recall, bdnf enhanced hippocampal memory representations and long-term performance. |
2021-10-04 |
2023-08-13 |
human |
| Xiuli Zhai, Jinying Li, Liya Li, Ye Sun, Xiaonan Zhang, Ying Xue, Jiaxin Lv, Ye Gao, Shouxin Li, Wei Yan, Shengming Yin, Zhaoyang Xia. L-lactate preconditioning promotes plasticity-related proteins expression and reduces neurological deficits by potentiating GPR81 signaling in rat traumatic brain injury model. Brain research. vol 1746. 2021-10-01. PMID:32531223. |
l-lactate preconditioning significantly increased the expression of gpr81, psd95, gap43, bdnf, and mct2 24 h after tbi in the cortex and hippocampus compared with the sham group. |
2021-10-01 |
2023-08-13 |
rat |
| Hajime Miyanishi, Atsumi Nitt. A Role of BDNF in the Depression Pathogenesis and a Potential Target as Antidepressant: The Modulator of Stress Sensitivity "Shati/Nat8l-BDNF System" in the Dorsal Striatum. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577589. |
we reviewed a novel finding of bdnf function in the dorsal striatum, which induces vulnerability to social stress, in addition to recent research progress regarding the brain regional functions of bdnf, including the prefrontal cortex, hippocampus, and nucleus accumbens. |
2021-10-01 |
2023-08-13 |
Not clear |
| Ruizhuo Chen, Aidan S Weitzner, Lara A McKennon, Laura K Fonke. Chronic circadian phase advance in male mice induces depressive-like responses and suppresses neuroimmune activation. Brain, behavior, & immunity - health. vol 17. 2021-10-01. PMID:34589820. |
further, cpa suppressed expression of brain-derived neurotrophic factor (bdnf) and pro-inflammatory cytokine interleukin-1 beta in the hippocampus. |
2021-10-01 |
2023-08-13 |
mouse |
| Yangliang Yang, Jing Yi, Mengzhi Pan, Baoji Hu, Hongwei Dua. Edaravone alleviated propofol-induced neural injury in developing rats by BDNF/TrkB pathway. Journal of cellular and molecular medicine. vol 25. issue 11. 2021-09-30. PMID:33932098. |
additionally, the intraperitoneal injection of edaravone, the intraperitoneal injection of the brain-derived neurotrophic factor (bdnf)-mimicking small compound (7,8 dihydroxyflavone) and the intracranial injection of the exogenous bdnf were all respectively effective in alleviating the propofol-induced neural apoptosis and inflammation in the hippocampus. |
2021-09-30 |
2023-08-13 |
rat |