| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bin Zhu, Zhi-Gang Wang, Jie Ding, Ning Liu, DA-Ming Wang, Liang-Cai Ding, Chun Yan. Chronic lipopolysaccharide exposure induces cognitive dysfunction without affecting BDNF expression in the rat hippocampus. Experimental and therapeutic medicine. vol 7. issue 3. 2021-10-21. PMID:24520281. |
chronic lipopolysaccharide exposure induces cognitive dysfunction without affecting bdnf expression in the rat hippocampus. |
2021-10-21 |
2023-08-12 |
rat |
| Bin Zhu, Zhi-Gang Wang, Jie Ding, Ning Liu, DA-Ming Wang, Liang-Cai Ding, Chun Yan. Chronic lipopolysaccharide exposure induces cognitive dysfunction without affecting BDNF expression in the rat hippocampus. Experimental and therapeutic medicine. vol 7. issue 3. 2021-10-21. PMID:24520281. |
therefore, the present study aimed to investigate the behavioral performance of rats receiving intraperitoneal injections of lps and to determine the expression levels of amyloid-β (aβ), brain-derived neurotrophic factor (bdnf) and pro-inflammatory cytokines in the hippocampus. |
2021-10-21 |
2023-08-12 |
rat |
| Bin Zhu, Zhi-Gang Wang, Jie Ding, Ning Liu, DA-Ming Wang, Liang-Cai Ding, Chun Yan. Chronic lipopolysaccharide exposure induces cognitive dysfunction without affecting BDNF expression in the rat hippocampus. Experimental and therapeutic medicine. vol 7. issue 3. 2021-10-21. PMID:24520281. |
however, the administration of lps did not elicit a statistically significant change in the expression level of bdnf in the hippocampus, compared with that in the control group (p>0.05). |
2021-10-21 |
2023-08-12 |
rat |
| Bin Zhu, Zhi-Gang Wang, Jie Ding, Ning Liu, DA-Ming Wang, Liang-Cai Ding, Chun Yan. Chronic lipopolysaccharide exposure induces cognitive dysfunction without affecting BDNF expression in the rat hippocampus. Experimental and therapeutic medicine. vol 7. issue 3. 2021-10-21. PMID:24520281. |
the results indicate that lps induces cognitive dysfunction, which is associated with increased expression levels of pro-inflammatory cytokines and aβ, but does not affect the expression of bdnf in the hippocampus. |
2021-10-21 |
2023-08-12 |
rat |
| Fan Zhang, Zhao-Qiong Zhu, DE-Xing Liu, Chao Zhang, Qi-Hai Gong, Yu-Hang Zh. Emulsified isoflurane anesthesia decreases brain-derived neurotrophic factor expression and induces cognitive dysfunction in adult rats. Experimental and therapeutic medicine. vol 8. issue 2. 2021-10-21. PMID:25009603. |
samples were taken in order to detect the plasma corticosterone concentration and the levels of hippocampal brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf), as well as the expression of bdnf and ngf in the hippocampal region. |
2021-10-21 |
2023-08-13 |
rat |
| Olubukola Kalejaiye, Babur H Bhatti, Robert E Taylor, Yousef Tizab. Nicotine Blocks the Depressogenic Effects of Alcohol: Implications for Drinking-Smoking Co-Morbidity. Journal of drug and alcohol research. vol 2. 2021-10-21. PMID:25309774. |
moreover, since hippocampal brain-derived neurotrophic factor (bdnf) has been strongly implicated in mood regulation and effectiveness of antidepressants, the level of this neurotrophic factor in the hippocampus was also evaluated. |
2021-10-21 |
2023-08-13 |
rat |
| Olubukola Kalejaiye, Babur H Bhatti, Robert E Taylor, Yousef Tizab. Nicotine Blocks the Depressogenic Effects of Alcohol: Implications for Drinking-Smoking Co-Morbidity. Journal of drug and alcohol research. vol 2. 2021-10-21. PMID:25309774. |
parallel to the behavioral changes, chronic alcohol resulted in a significant decrease in hippocampal bdnf, which was normalized by nicotine. |
2021-10-21 |
2023-08-13 |
rat |
| Asia Afzal, Zehra Batool, Sadia Sadir, Laraib Liaquat, Sidrah Shahzad, Saiqa Tabassum, Saara Ahmad, Noor Kamil, Tahira Perveen, Saida Haide. Therapeutic Potential of Curcumin in Reversing the Depression and Associated Pseudodementia via Modulating Stress Hormone, Hippocampal Neurotransmitters, and BDNF Levels in Rats. Neurochemical research. vol 46. issue 12. 2021-10-21. PMID:34409523. |
therapeutic potential of curcumin in reversing the depression and associated pseudodementia via modulating stress hormone, hippocampal neurotransmitters, and bdnf levels in rats. |
2021-10-21 |
2023-08-13 |
rat |
| Asia Afzal, Zehra Batool, Sadia Sadir, Laraib Liaquat, Sidrah Shahzad, Saiqa Tabassum, Saara Ahmad, Noor Kamil, Tahira Perveen, Saida Haide. Therapeutic Potential of Curcumin in Reversing the Depression and Associated Pseudodementia via Modulating Stress Hormone, Hippocampal Neurotransmitters, and BDNF Levels in Rats. Neurochemical research. vol 46. issue 12. 2021-10-21. PMID:34409523. |
in addition to this, high corticosterone levels and decreased hippocampal bdnf, 5-ht, dopamine (da), and acetylcholine (ach) levels were also observed in depressed animals. |
2021-10-21 |
2023-08-13 |
rat |
| Yousef Baghcheghi, Farimah Beheshti, Hossein Salmani, Mahmoud Hossein. Brain‑derived neurotrophic factor and nitric oxide contribute to protective effects of rosiglitazone on learning and memory in hypothyroid rats. Acta neurobiologiae experimentalis. vol 81. issue 3. 2021-10-21. PMID:34672293. |
hypothyroidism also decreased hippocampal bdnf levels, increased no metabolites, and induced oxidative damage in the brain. |
2021-10-21 |
2023-08-13 |
rat |
| Philip W Gol. The PPARg System in Major Depression: Pathophysiologic and Therapeutic Implications. International journal of molecular sciences. vol 22. issue 17. 2021-10-20. PMID:34502154. |
brain-derived neurotrophic factor (bdnf) is markedly depleted in these areas, and is thought to contribute to the neurodegeneration of the subgenual prefrontal cortex and the hippocampus. |
2021-10-20 |
2023-08-13 |
Not clear |
| Pablo J Lituma, Hyung-Bae Kwon, Karina Alviña, Rafael Luján, Pablo E Castill. Presynaptic NMDA receptors facilitate short-term plasticity and BDNF release at hippocampal mossy fiber synapses. eLife. vol 10. 2021-10-19. PMID:34061025. |
presynaptic nmda receptors facilitate short-term plasticity and bdnf release at hippocampal mossy fiber synapses. |
2021-10-19 |
2023-08-13 |
Not clear |
| M Kusmider, A Faron-Górecka, J Solich, P Pabian, M Dziedzicka-Wasylewsk. Time-course of changes in key catecholaminergic receptors and trophic systems in rat brain after antidepressant administration. Neurochemistry international. vol 141. 2021-10-18. PMID:33132141. |
these alterations include the downregulation of β1, β2, and α1 adrenergic receptors, upregulation of α2-adrenergic receptors and dopamine d2 receptors, and increased expression of bdnf in the hippocampus. |
2021-10-18 |
2023-08-13 |
rat |
| Kensuke Nakajima, Shigeru Ois. Upregulating Effect of Wheat on Brain-Derived Neurotrophic Factor in Human Lung Adenocarcinoma A549 Cells. Journal of oleo science. vol 70. issue 6. 2021-10-15. PMID:33967169. |
the neurotrophic hypothesis of depression, that is, a deficiency in hippocampal brain-derived neurotrophic factor (bdnf) leads to depression, has gained widespread acceptance. |
2021-10-15 |
2023-08-13 |
human |
| Kensuke Nakajima, Shigeru Ois. Upregulating Effect of Wheat on Brain-Derived Neurotrophic Factor in Human Lung Adenocarcinoma A549 Cells. Journal of oleo science. vol 70. issue 6. 2021-10-15. PMID:33967169. |
peripheral bdnf can traverse the blood-brain barrier and reach the hippocampus; accordingly, substances that upregulate bdnf production in peripheral tissues may be useful in the treatment of depression. |
2021-10-15 |
2023-08-13 |
human |
| Yao-Ching Fang, Jia-Yu Hsieh, Amelia Nur Vidyanti, Chih-Hao Yang, Jing-Shiun Jan, Kang-Wei Chang, Chaur-Jong Hu, Yong-Kwang T. HDACi protects against vascular cognitive impairment from CCH injury via induction of BDNF-related AMPA receptor activation. Journal of cellular and molecular medicine. vol 25. issue 15. 2021-10-15. PMID:34216182. |
the cortex and hippocampus of mice were harvested at 3 months after bccao, and levels of bdnf, ampa receptor and dopamine receptors (d1, d2 and d3) were studied using western blotting analysis or immunohistochemistry. |
2021-10-15 |
2023-08-13 |
mouse |
| Zhijun Jiang, Zemeng Zhu, Mingyue Zhao, Wei Wang, Haonan Li, Dexiang Liu, Fang Pa. H3K9me2 regulation of BDNF expression in the hippocampus and medial prefrontal cortex is involved in the depressive-like phenotype induced by maternal separation in male rats. Psychopharmacology. vol 238. issue 10. 2021-10-15. PMID:34328517. |
h3k9me2 regulation of bdnf expression in the hippocampus and medial prefrontal cortex is involved in the depressive-like phenotype induced by maternal separation in male rats. |
2021-10-15 |
2023-08-13 |
rat |
| Ermelinda De Meo, Emilio Portaccio, Elio Prestipino, Benedetta Nacmias, Silvia Bagnoli, Lorenzo Razzolini, Luisa Pastò, Claudia Niccolai, Benedetta Goretti, Angelo Bellinvia, Mattia Fonderico, Antonio Giorgio, Maria Laura Stromillo, Massimo Filippi, Sandro Sorbi, Nicola De Stefano, Maria Pia Amat. Effect of BDNF Val66Met polymorphism on hippocampal subfields in multiple sclerosis patients. Molecular psychiatry. 2021-10-15. PMID:34650209. |
effect of bdnf val66met polymorphism on hippocampal subfields in multiple sclerosis patients. |
2021-10-15 |
2023-08-13 |
Not clear |
| Ermelinda De Meo, Emilio Portaccio, Elio Prestipino, Benedetta Nacmias, Silvia Bagnoli, Lorenzo Razzolini, Luisa Pastò, Claudia Niccolai, Benedetta Goretti, Angelo Bellinvia, Mattia Fonderico, Antonio Giorgio, Maria Laura Stromillo, Massimo Filippi, Sandro Sorbi, Nicola De Stefano, Maria Pia Amat. Effect of BDNF Val66Met polymorphism on hippocampal subfields in multiple sclerosis patients. Molecular psychiatry. 2021-10-15. PMID:34650209. |
given bdnf relevance on the hippocampus, we aimed to explore bdnf val66met polymorphism effect on hippocampal subfield volumes and its role in cognitive functioning in ms patients. |
2021-10-15 |
2023-08-13 |
Not clear |
| Ermelinda De Meo, Emilio Portaccio, Elio Prestipino, Benedetta Nacmias, Silvia Bagnoli, Lorenzo Razzolini, Luisa Pastò, Claudia Niccolai, Benedetta Goretti, Angelo Bellinvia, Mattia Fonderico, Antonio Giorgio, Maria Laura Stromillo, Massimo Filippi, Sandro Sorbi, Nicola De Stefano, Maria Pia Amat. Effect of BDNF Val66Met polymorphism on hippocampal subfields in multiple sclerosis patients. Molecular psychiatry. 2021-10-15. PMID:34650209. |
compared to bdnf val66val, val66met ms patients had higher volume in bilateral hippocampal tail; ca1, ml, ca3, ca4, and gcl-dg of left hippocampal head; ca1, ml, and ca3 of the left hippocampal body; left hata and presubiculum of the right hippocampal head. |
2021-10-15 |
2023-08-13 |
Not clear |