| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Koilmani Emmanuvel Raja. Olfactory learning and memory in the greater short-nosed fruit bat Cynopterus sphinx: the influence of conspecifics distress calls. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 207. issue 5. 2021-11-10. PMID:34426872. |
further, protein phosphatase-1 (pp-1) expression was significantly lower, and the expression levels of e1a homologue of creb-binding protein (cbp) (p300), brain-derived neurotrophic factor (bdnf) and its tyrosine kinase b1 (trkb1) receptor were significantly higher in the hippocampus of control/bats exposed to modified calls compared to distress calls/pbs of distress call-exposed bats. |
2021-11-10 |
2023-08-13 |
human |
| Koilmani Emmanuvel Raja. Olfactory learning and memory in the greater short-nosed fruit bat Cynopterus sphinx: the influence of conspecifics distress calls. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 207. issue 5. 2021-11-10. PMID:34426872. |
exposure to the call possibly alters the reciprocal interaction between the amygdala and the hippocampus, accordingly regulating the expression levels of pp1, p300 and bdnf and its receptor trkb1 following training to the novel odor. |
2021-11-10 |
2023-08-13 |
human |
| Wen-Zhu Wang, Xu Liu, Zheng-Yi Yang, Yi-Zheng Wang, Hai-Tao L. Diffusion tensor imaging of the hippocampus reflects the severity of hippocampal injury induced by global cerebral ischemia/reperfusion injury. Neural regeneration research. vol 17. issue 4. 2021-11-10. PMID:34472484. |
although hippocampal microstructure, brain-derived neurotrophic factor (bdnf), and tropomyosin-related kinase b (trkb) levels are closely related to nerve injury and the repair process after gci/ri, whether these indicators can reflect the severity of such hippocampal injury remains unknown. |
2021-11-10 |
2023-08-13 |
rat |
| Wen-Zhu Wang, Xu Liu, Zheng-Yi Yang, Yi-Zheng Wang, Hai-Tao L. Diffusion tensor imaging of the hippocampus reflects the severity of hippocampal injury induced by global cerebral ischemia/reperfusion injury. Neural regeneration research. vol 17. issue 4. 2021-11-10. PMID:34472484. |
the results revealed that after gci/ri, while neurological function was not related to bdnf and trkb levels, it was related to hippocampal fractional anisotropy. |
2021-11-10 |
2023-08-13 |
rat |
| Mythri Chittilla, Nuraly S Akimbekov, Mohammed S Razzaqu. High-fat diet-associated cognitive decline: Is zinc finger protein 1 (ZPR1) the molecular connection? Current research in physiology. vol 4. 2021-11-10. PMID:34746842. |
the two modalities of cognitive decline caused by low concentrations of zpr1 are reduced brain-derived growth factor (bdnf) synthesis and neuron death, both occurring in the hippocampus. |
2021-11-10 |
2023-08-13 |
Not clear |
| Juandré Lambertus Bernardus Saayman, Stephanus Frederik Steyn, Christiaan Beyers Brin. The long-term bio-behavioural effects of juvenile sildenafil treatment in Sprague-Dawley versus flinders sensitive line rats. Acta neuropsychiatrica. vol 33. issue 4. 2021-11-09. PMID:33593460. |
to investigate the long-term effects of juvenile sub-chronic sildenafil (sil) treatment on the depressive-like behaviour and hippocampal brain-derived neurotrophic factor (bdnf) levels of adult sprague-dawley (sd) versus flinders sensitive line (fsl) rats. |
2021-11-09 |
2023-08-13 |
rat |
| Yosefa Avraham, David Mankuta, Leah Lipsker, Lia Vorobiev, Sigalit Patael, Golda Hassid, Elliot M Berry, Amnon Albec. Beta-Carotene derivatives as novel therapy for the prevention and treatment of autistic symptoms. Bioorganic chemistry. vol 115. 2021-11-09. PMID:34392174. |
the following biochemical and molecular biology parameters were also examined: serum oxt; gene expression in hippocampus and hypothalamus of cd 38, oxt, oxt receptor, bdnf, and retinoic acid receptor. |
2021-11-09 |
2023-08-13 |
mouse |
| Aya Galal, Wesam M El-Bakly, Sara S El-Kilany, Azza A Ali, Ebtehal El-Demerdas. Fenofibrate ameliorates olanzapine's side effects without altering its central effect: emphasis on FGF-21-adiponectin axis. Behavioural pharmacology. vol 32. issue 8. 2021-11-09. PMID:34637209. |
treatment with olanzapine (6 mg/kg, intraperitoneally) or fenofibrate (100 mg/kg, orally) have been started 5 weeks after isolation, then behavioral tests, hippocampal content of neurotransmitters, and brain-derived neurotrophic factor (bdnf) were assessed. |
2021-11-09 |
2023-08-13 |
rat |
| Aya Galal, Wesam M El-Bakly, Sara S El-Kilany, Azza A Ali, Ebtehal El-Demerdas. Fenofibrate ameliorates olanzapine's side effects without altering its central effect: emphasis on FGF-21-adiponectin axis. Behavioural pharmacology. vol 32. issue 8. 2021-11-09. PMID:34637209. |
co-treatment showed additive effects in improving hippocampal bdnf level. |
2021-11-09 |
2023-08-13 |
rat |
| Madhuparna Banerjee, Rekha R Sheno. Emphasizing roles of BDNF promoters and inducers in Alzheimer's disease for improving impaired cognition and memory. Journal of basic and clinical physiology and pharmacology. 2021-11-09. PMID:34751526. |
drugs and herbals promote neuroprotection by increasing the hippocampus' bdnf level in various disease-induced animal models for neurodegeneration. |
2021-11-09 |
2023-08-13 |
Not clear |
| Francisco J Flores-Ramirez, Anapaula Themann, Jorge A Sierra-Fonseca, Israel Garcia-Carachure, Samuel A Castillo, Minerva Rodriguez, Omar Lira, Joshua Preciado-Piña, Brandon L Warren, Alfred J Robison, Sergio D Iñigue. Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33833356. |
an additional goal was to assess the impact of adolescent flx pretreatment, and its re-exposure in adulthood, on serotonin transporters (5-htt) and brain-derived-neurotrophic-factor (bdnf)-related signaling markers (trkb-erk1/2-creb-probdnf-mbdnf) within the hippocampus and prefrontal cortex. |
2021-11-08 |
2023-08-13 |
mouse |
| Shanshan Liu, Qing Liu, Yanjie Ju, Lei Li. Downregulation of miR-383 reduces depression-like behavior through targeting Wnt family member 2 (Wnt2) in rats. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33927285. |
downregulation of mir-383 significantly inhibited the apoptosis and inflammatory response of hippocampal neurons, and increased the expression levels of gfap, bdnf and creb which were impacted in depression, as well as neurotransmitters, then attenuated neural injury in rats induced by cums. |
2021-11-08 |
2023-08-13 |
rat |
| Haidar Tafner Curi, Clarissa Tavares Dias, Maria Laura Monteiro da Luz Camargo, Paula Dos Santos Gomez, Moisés Felipe Pereira Gomes, José Ivo Araujo Beserra-Filho, Alessandra Medeiros, Alessandra Mussi Ribeiro, Fernando Moreira Simabuco, Rafael Herling Lambertucci, Cristiano Mendes-da-Silv. Maternal high-fat diet increases anhedonic behavior and modulates hippocampal Mash1 and BDNF expression in adult offspring. Neuroscience letters. vol 764. 2021-11-08. PMID:34509569. |
maternal high-fat diet increases anhedonic behavior and modulates hippocampal mash1 and bdnf expression in adult offspring. |
2021-11-08 |
2023-08-13 |
Not clear |
| Ke-Zhuo Chen, Shi Chen, Jie-Yi Ren, Shi Lin, Ming-Jun Xiao, Li Cheng, Xiao-Chuan Y. [Antidepressant effect of acidic polysaccharides from Poria and their regulation of neurotransmitters and NLRP3 pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 19. 2021-11-08. PMID:34738405. |
the results showed that compared with the model group, acidic polysaccharides from poria at the low-, medium-, and high-doses(0.1, 0.3 and 0.5 g·kg~(-1)·d~(-1)) all improved the depression-like behavior of rats, increased the number of neurons and the levels of bdnf, 5-ht, 5-hiaa, da, and ne in the hippocampus, and reduced glu and serum il-1β, il-18, and tnf-α levels. |
2021-11-08 |
2023-08-13 |
rat |
| Ping Zheng, He Bin, Wei Che. Inhibition of microRNA-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating BDNF. Cancer cell international. vol 19. issue 1. 2021-11-05. PMID:31049031. |
inhibition of microrna-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating bdnf. |
2021-11-05 |
2023-08-13 |
rat |
| Ping Zheng, He Bin, Wei Che. Inhibition of microRNA-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating BDNF. Cancer cell international. vol 19. issue 1. 2021-11-05. PMID:31049031. |
the aim of this study is to explore the effect of microrna-103a (mir-103a) on astrocytes activation and hippocampal neuron injury in epilepsy rats by targeting brain-derived neurotrophic factor (bdnf). |
2021-11-05 |
2023-08-13 |
rat |
| Simon Couly, Allison Carles, Morgane Denus, Lorraine Benigno-Anton, Florence Maschat, Tangui Mauric. Exposure of R6/2 mice in an enriched environment augments P42 therapy efficacy on Huntington's disease progression. Neuropharmacology. vol 186. 2021-11-05. PMID:33516737. |
the p42 + ee combination also significantly decreased aggregated htt levels in the hippocampus, striatum and cortex, and increased bdnf levels in the cortex and striatum. |
2021-11-05 |
2023-08-13 |
mouse |
| Gwo-Ching Sun, Yi-Ju Lee, Yi-Ching Lee, Hsien-Fu Yu, Dean-Chuan Wan. Exercise prevents the impairment of learning and memory in prenatally phthalate-exposed male rats by improving the expression of plasticity-related proteins. Behavioural brain research. vol 413. 2021-11-04. PMID:34245761. |
the activity-regulated cytoskeleton associated protein (arc) is induced by bdnf and n-methyl-d-aspartic acid receptor (nmdar), contributing to functional modification of neuroplasticity in the hippocampus. |
2021-11-04 |
2023-08-13 |
rat |
| Sheng Wang, Guilan Huang, Jie Yan, Changxi Li, Jianwen Feng, Qi Chen, Xiaomeng Zheng, Haobin Li, Jiangchao Li, Lijing Wang, Huimin L. Influence of aging on chronic unpredictable mild stress-induced depression-like behavior in male C57BL/6J mice. Behavioural brain research. vol 414. 2021-11-04. PMID:34302872. |
moreover, lessening and impairment of hippocampal neurons was found in stressed mice at the age of 18 weeks, which was correlated with increased relative mrna expression levels of inflammatory cytokines bdnf, htr1a, and il-6 in the hippocampus. |
2021-11-04 |
2023-08-13 |
mouse |
| Samantha T Reyes, Robert M J Deacon, Scarlett G Guo, Francisco J Altimiras, Jessa B Castillo, Berend van der Wildt, Aimara P Morales, Jun Hyung Park, Daniel Klamer, Jarrett Rosenberg, Lindsay M Oberman, Nell Rebowe, Jeffrey Sprouse, Christopher U Missling, Christopher R McCurdy, Patricia Cogram, Walter E Kaufmann, Frederick T Chi. Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy. Scientific reports. vol 11. issue 1. 2021-11-04. PMID:34433831. |
it also restored levels of bdnf, a converging point of many synaptic regulators, in the hippocampus. |
2021-11-04 |
2023-08-13 |
mouse |