| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongxin Zhang, Xuegang Li, Xue Zhou, Pengqi Gong, Yong Zha. U-fiber-based biosensor for temperature-compensated acetylcholine-specific measurement. Optics letters. vol 48. issue 8. 2023-04-14. PMID:37058661. |
label-free detection of acetylcholine (ach) was achieved by immobilizing acetylcholinesterase (ache) on optical fibers. |
2023-04-14 |
2023-08-14 |
Not clear |
| Mohammad Ashafaq, Sohail Hussain, Saeed Alshahrani, Rahimullah Siddiqui, Mohammad Intakhab Alam, Manal Mohamed Elhassan Taha, Yosif Almoshari, Saad S Alqahtani, Abdulmajeed M Jali, Hashim M Aljohan. Neuroprotective Effects of Nano-Curcumin against Cypermethrin Associated Oxidative Stress and Up-Regulation of Apoptotic and Inflammatory Gene Expression in Rat Brains. Antioxidants (Basel, Switzerland). vol 12. issue 3. 2023-03-29. PMID:36978892. |
the toxic effects are supposed to be mediated by modifying the sodium channels, reducing na-k atpase, acetylcholine esterase (ache), and monoamine oxidase (mao). |
2023-03-29 |
2023-08-14 |
rat |
| Wonn Shweyi Thet Tun, Apichart Saenchoopa, Sakda Daduang, Jureerat Daduang, Sirinan Kulchat, Rina Patramano. Electrochemical biosensor based on cellulose nanofibers/graphene oxide and acetylcholinesterase for the detection of chlorpyrifos pesticide in water and fruit juice. RSC advances. vol 13. issue 14. 2023-03-27. PMID:36968027. |
ache is an enzyme that is essential for neurotransmission and catalyzes the conversion of acetylcholine (atch) into thiocholine and acetic acid. |
2023-03-27 |
2023-08-14 |
Not clear |
| Vahulabaranan Rajagopalan, Swethaa Venkataraman, Devi Sri Rajendran, Vaidyanathan Vinoth Kumar, Vaithyanathan Vasanth Kumar, Gayathri Rangasam. Acetylcholinesterase biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine neurotransmitter: A literature review. Environmental research. 2023-03-22. PMID:36948285. |
over the past few decades, acetylcholinesterase (ache) biosensors have emerged as a sensitive and reliable tool for the electrochemical detection of neurotoxic pesticides and acetylcholine. |
2023-03-22 |
2023-08-14 |
human |
| Vahulabaranan Rajagopalan, Swethaa Venkataraman, Devi Sri Rajendran, Vaidyanathan Vinoth Kumar, Vaithyanathan Vasanth Kumar, Gayathri Rangasam. Acetylcholinesterase biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine neurotransmitter: A literature review. Environmental research. 2023-03-22. PMID:36948285. |
this review summarizes the advancements in ache biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine over the past two decades. |
2023-03-22 |
2023-08-14 |
human |
| Jeyaraj Jeyavani, Baskaralingam Vaseehara. Combined toxic effects of environmental predominant microplastics and ZnO nanoparticles in freshwater snail Pomaceae paludosa. Environmental pollution (Barking, Essex : 1987). 2023-03-12. PMID:36907240. |
where alteration in acetylcholine esterase (ache) activity and decreased digestive enzymes (esterase and alkaline phosphatase) activities were observed in both individual and combined exposed groups. |
2023-03-12 |
2023-08-14 |
cat |
| b' Rudolf Vrabec, Gerald Blunden, Lucie Cahl\\xc3\\xadkov\\xc3\\xa. Natural Alkaloids as Multi-Target Compounds towards Factors Implicated in Alzheimer\'s Disease. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36901826.' |
the current treatment, based on the cholinergic hypothesis, is only symptomatic and mainly involves the restoration of acetylcholine (ach) levels through the inhibition of acetylcholinesterase (ache). |
2023-03-11 |
2023-08-14 |
Not clear |
| Abdussamat Güze. Relationship Between Phenolic Content Determined by LC-MS/MS and Antioxidant Capacity and Enzyme Inhibition of Cyclotrichium Niveum L. Chemistry & biodiversity. 2023-03-09. PMID:36891984. |
the phytochemical composition of the plant, inhibition of acetylcholinesterase (ache) (which hydrolyzes the neurotransmitter acetylcholine), inhibition of paraoxonase for antiatherosclerotic activity (hpon 1) (which detoxifies organophosphates), and antioxidant capacity of this plant. |
2023-03-09 |
2023-08-14 |
Not clear |
| Sanjay Yadav, Punita Aggarwal, Faiz Khan, Gopal Khodve, Dibyasundar Padhy, Poonam Yadav, Sugato Banerje. β-sitosterol protects against Aluminium chloride-mediated neurotoxicity. Current Alzheimer research. 2023-03-09. PMID:36892031. |
the corticohippocampal region of the brain was isolated for acetylcholinesterase (ache), acetylcholine (ach), and gsh estimation. |
2023-03-09 |
2023-08-14 |
mouse |
| Atallah F Ahmed, Zhi-Hong Wen, Ahmed H Bakheit, Omer A Basudan, Hazem A Ghabbour, Abdullah Al-Ahmari, Chien-Wei Fen. A Major Plants (Basel, Switzerland). vol 11. issue 5. 2023-03-08. PMID:35270118. |
a study of molecular docking and molecular dynamic (md) simulation of ir3g and its aglycone isorhamnetin (ir) against human acetylcholine esterase (ache), monoamine oxidase b (mao-b), and polo-like kinase-2 (plk2) was performed and further outlined a putative mechanism in modulating neurodegenerative diseases such as pd. |
2023-03-08 |
2023-08-16 |
human |
| Long Sun, Xian Li, Chenjing Ma, Zhao He, Xin Zhang, Chengye Wang, Min Zhao, Jin Gan, Ying Fen. Improving Effect of the Policosanol from Foods (Basel, Switzerland). vol 11. issue 14. 2023-03-08. PMID:35885338. |
after mwm testing, the levels of acetylcholine (ach), acetylcholinesterase (ache), superoxide dismutase (sod), malondialdehyde (mda), and glutathione (gsh) that were present in brain tissue were determined using assay kits. |
2023-03-08 |
2023-08-16 |
mouse |
| Marlene Valentino, Anna Imbriano, Angelo Tricase, Flavio Della Pelle, Dario Compagnone, Eleonora Macchia, Luisa Torsi, Paolo Bollella, Nicoletta Ditarant. Electropolymerized molecularly imprinted polypyrrole film for dimethoate sensing: investigation on template removal after the imprinting process. Analytical methods : advancing methods and applications. 2023-03-02. PMID:36861684. |
dmt is an inhibitor of acetylcholinesterase (ache), which can lead to the accumulation of acetylcholine and result in symptoms related to the autonomous and central nervous systems. |
2023-03-02 |
2023-08-14 |
Not clear |
| Aleksandar R Zivkovic, Georgina M Paul, Stefan Hofer, Karsten Schmidt, Thorsten Brenner, Markus A Weigand, Sebastian O Decke. Increased Enzymatic Activity of Acetylcholinesterase Indicates the Severity of the Sterile Inflammation and Predicts Patient Outcome following Traumatic Injury. Biomolecules. vol 13. issue 2. 2023-02-25. PMID:36830636. |
acetylcholinesterase (ache), an enzyme responsible for the hydrolysis of acetylcholine, plays an essential role in controlling cholinergic activity. |
2023-02-25 |
2023-08-14 |
Not clear |
| Preeti Bhatt, Manju Solra, Smarak Islam Chaudhury, Subinoy Ran. Metal Coordination-Driven Supramolecular Nanozyme as an Effective Colorimetric Biosensor for Neurotransmitters and Organophosphorus Pesticides. Biosensors. vol 13. issue 2. 2023-02-25. PMID:36832043. |
the detection strategy for op chemicals was based on the inhibition of acetylcholine esterase (ache) activity: a key enzyme that is responsible for the hydrolysis of acetylthiocholine (atch). |
2023-02-25 |
2023-08-14 |
Not clear |
| Aravinda Babu, Mathew John, M J Liji, E Maria, S J Bhaskar, B K Binukmar, Ayyiliath M Sajith, Eeda Koti Reddy, K V Dileep, K Suni. Sub-pocket-focused designing of tacrine derivatives as potential acetylcholinesterase inhibitors. Computers in biology and medicine. vol 155. 2023-02-25. PMID:36841058. |
human acetylcholinesterase (hache) has a potential role in the management of acetylcholine, one of the neurotransmitters that modulate the overall activity of cholinergic system, ache inhibitors have a greater impact in the therapeutics. |
2023-02-25 |
2023-08-14 |
human |
| Christina Rabeler, TaiXi Gong, Danielle Ireland, Olivier Cochet-Escartin, Eva-Maria S Collin. Acetylcholinesterase Activity Staining in Freshwater Planarians. Current protocols. vol 3. issue 2. 2023-02-17. PMID:36799654. |
the serine hydrolase acetylcholinesterase (ache) is an important neuronal enzyme which catalyzes the hydrolysis of the neurotransmitter acetylcholine and other choline esters. |
2023-02-17 |
2023-08-14 |
Not clear |
| Christina Rabeler, TaiXi Gong, Danielle Ireland, Olivier Cochet-Escartin, Eva-Maria S Collin. Acetylcholinesterase Activity Staining in Freshwater Planarians. Current protocols. vol 3. issue 2. 2023-02-17. PMID:36799654. |
the breakdown of acetylcholine by ache terminates synaptic transmission and regulates neuromuscular communication. |
2023-02-17 |
2023-08-14 |
Not clear |
| Stergiani-Chrysovalanti Peitzika, Eleni Pontik. A Review on Recent Approaches on Molecular Docking Studies of Novel Compounds Targeting Acetylcholinesterase in Alzheimer Disease. Molecules (Basel, Switzerland). vol 28. issue 3. 2023-02-11. PMID:36770750. |
low levels of acetylcholine and abnormal levels of beta-amyloid, t protein aggregation, inflammation, and oxidative stress, have been associated with ad, and therefore, research has been oriented towards the cholinergic system and primarily on acetylcholinesterase (ache) inhibitors. |
2023-02-11 |
2023-08-14 |
Not clear |
| Hisashi Inoue, Teruyuki Tachibana, Tomohiro Bito, Jiro Arim. Acetylation of amines and alcohols catalyzed by acetylcholinesterase from Pseudomonas aeruginosa PAO1. Enzyme and microbial technology. vol 165. 2023-02-08. PMID:36753877. |
therefore, we evaluated acetylation of the amine and hydroxyl group by ache, using acetylcholine and ethyl acetate as the acetyl donor. |
2023-02-08 |
2023-08-14 |
Not clear |
| Melvin Selim Atay, Suat Sari, Ebru Bodu. Molecular and Computational Analysis Identify Statins as Selective Inhibitors of Human Butyrylcholinesterase. The protein journal. 2023-01-17. PMID:36648628. |
cholinesterase enzyme family consists of acetylcholinesterase (ache, 3.1.1.7), the major enzyme responsible for hydrolysis of acetylcholine at cholinergic synapses, and butyrylcholinesterase (bche, 3.1.1.8) a detoxification enzyme of plasma. |
2023-01-17 |
2023-08-14 |
human |