| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carsten Eggers, Karl Herholz, Elke Kalbe, Wolf-Dieter Heis. Cortical acetylcholine esterase activity and ApoE4-genotype in Alzheimer disease. Neuroscience letters. vol 408. issue 1. 2007-04-03. PMID:16996687. |
positron emission tomography (pet) studies have demonstrated reduced acetylcholine esterase (ache) activity as an indicator of cholinergic impairment, which is a main pathogenic process in alzheimer's disease (ad). |
2007-04-03 |
2023-08-12 |
human |
| Joachim Hartmann, Cornelia Kiewert, Ellen G Duysen, Oksana Lockridge, Nigel H Greig, Jochen Klei. Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity. Journal of neurochemistry. vol 100. issue 5. 2007-04-02. PMID:17212694. |
we have used in vivo microdialysis to investigate the regulation of hippocampal acetylcholine (ach) levels in mice that are devoid of ache (ache-/- mice). |
2007-04-02 |
2023-08-12 |
mouse |
| Bernd Kallmünzer, Björn Sörensen, Winfried L Neuhuber, Jürgen Wör. Heterogeneity of neuromuscular junctions in striated muscle of human esophagus demonstrated by triple staining for the vesicular acetylcholine transporter, alpha-bungarotoxin, and acetylcholinesterase. Cell and tissue research. vol 324. issue 2. 2007-03-28. PMID:16437206. |
during studies on enteric co-innervation in the human esophagus, we found that not all acetylcholinesterase (ache)-positive motor endplates stained for alpha-bungarotoxin (alpha-bt) and the vesicular acetylcholine transporter (vacht), respectively. |
2007-03-28 |
2023-08-12 |
human |
| Bernd Kallmünzer, Björn Sörensen, Winfried L Neuhuber, Jürgen Wör. Heterogeneity of neuromuscular junctions in striated muscle of human esophagus demonstrated by triple staining for the vesicular acetylcholine transporter, alpha-bungarotoxin, and acetylcholinesterase. Cell and tissue research. vol 324. issue 2. 2007-03-28. PMID:16437206. |
based on these results, we suggest that, in human esophagus, (1) the most reliable method for staining motor endplates is presently ache histochemistry, (2) alpha-bt-sensitive and alpha-bt-resistant nicotinic acetylcholine receptors exist in neuromuscular junctions, and (3) different types of vacht or transport mechanisms for acetylcholine probably exist in neuromuscular junctions. |
2007-03-28 |
2023-08-12 |
human |
| Ulrike Holzgrabe, Petra Kapková, Vildan Alptüzün, Josef Scheiber, Eva Kugelman. Targeting acetylcholinesterase to treat neurodegeneration. Expert opinion on therapeutic targets. vol 11. issue 2. 2007-03-22. PMID:17227232. |
thus, the aim of many treatment regimens is to support this system either by means of muscarinic agonists or by inhibitors of acetylcholinesterase (ache), the latter being able to increase the concentration of acetylcholine. |
2007-03-22 |
2023-08-12 |
Not clear |
| Slawomir Gralewic. [Possible consequences of acetylcholinesterase inhibition in organophosphate poisoning. Discussion continued]. Medycyna pracy. vol 57. issue 3. 2007-03-20. PMID:17125036. |
numerous toxicologists still believe that the only function of acetylcholinesterase (ache) is to catalyse the hydrolysis of acetylcholine (ach), and that the toxicity of organophosphorous pesticides (op) results from their ability to switch this function off. |
2007-03-20 |
2023-08-12 |
Not clear |
| Ana-Lourdes Oropesa, Marcos Pérez-López, David Hernández, Jesús-Pablo García, Luis-Eusebio Fidalgo, Ana López-Beceiro, Francisco Sole. Acetylcholinesterase activity in seabirds affected by the Prestige oil spill on the Galician coast (NW Spain). The Science of the total environment. vol 372. issue 2-3. 2007-03-15. PMID:17113132. |
physiological levels of brain ache, expressed in nmol acetylcholine hydrolysed min(-1) mg(-1) protein were similar in non-exposed common guillemot (388.6+/-95.0) and atlantic puffin (474.0+/-60.7), however, razorbill values were higher (644.6+/-66.9). |
2007-03-15 |
2023-08-12 |
Not clear |
| Tomoko Koike, Shigeyuki Uno, Michiyasu Ishizawa, Hideo Takahashi, Kazumasa Ikeda, Shinichi Yokota, Makoto Makishim. The heat shock protein inhibitor KNK437 induces neurite outgrowth in PC12 cells. Neuroscience letters. vol 410. issue 3. 2007-02-27. PMID:17055158. |
ngf, and not knk437, induced acetylcholine esterase (ache) activity, a functional differentiation marker, indicating that knk437 utilizes a mechanism distinct from that of ngf. |
2007-02-27 |
2023-08-12 |
rat |
| Silvia Ravera, Carla Falugi, Daniela Calzia, Isidoro M Pepe, Isabella Panfoli, Alessandro Morell. First cell cycles of sea urchin Paracentrotus lividus are dramatically impaired by exposure to extremely low-frequency electromagnetic field. Biology of reproduction. vol 75. issue 6. 2007-02-26. PMID:16957026. |
moreover, ache inhibitors seem to induce the same teratological effects as those caused by the field, while blockers of acetylcholine (ach) receptors are able to antagonize those effects. |
2007-02-26 |
2023-08-12 |
Not clear |
| Susana Nieto-Cerón, Luis F Sánchez del Campo, Encarnación Muñoz Delgado, Cecilio J Vidal, Francisco Javier Campo. Thymus acetylcholinesterase activity is reduced in mice with congenital muscular dystrophy. Journal of molecular neuroscience : MN. vol 30. issue 1-2. 2007-02-23. PMID:17192623. |
ache and bche are involved through catalytic and noncatalytic actions in multiple processes, such as hydrolysis of acetylcholine (ach), morphogenesis, hematopoiesis, and tumorigenesis (soreq and seidman, 2001). |
2007-02-23 |
2023-08-12 |
mouse |
| María Fernanda Montenegro, Francisco Ruiz-Espejo, Francisco Javier Campoy, Encarnación Muñoz-Delgado, María Páez de la Cadena, Juan Cabezas-Herrera, Cecilio J Vida. Acetyl- and butyrylcholinesterase activities decrease in human colon adenocarcinoma. Journal of molecular neuroscience : MN. vol 30. issue 1-2. 2007-02-23. PMID:17192624. |
apart from the hydrolysis of acetylcholine (ach), acetyl- (ache) and butyrylcholinesterase (bche), through noncatalytic mechanisms, intervene in hematopoiesis, morphogenesis, and neurogenesis (layer and willbold, 1995; soreq and seidman, 2001). |
2007-02-23 |
2023-08-12 |
human |
| Maria-Ximena Silveyra, Maria-Salud García-Ayllón, Miguel Calero, Javier Sáez-Valer. Altered glycosylation of acetylcholinesterase in the Creutzfeldt-Jakob cerebrospinal fluid. Journal of molecular neuroscience : MN. vol 30. issue 1-2. 2007-02-23. PMID:17192630. |
the potential importance of these variants is increased by the possibility that ache has roles other than acetylcholine hydrolysis. |
2007-02-23 |
2023-08-12 |
Not clear |
| b' Emmanuelle Girard, V\\xc3\\xa9ronique Bernard, Shelley Camp, Palmer Taylor, Eric Krejci, Jordi Molg\\xc3\\xb. Remodeling of the neuromuscular junction in mice with deleted exons 5 and 6 of acetylcholinesterase. Journal of molecular neuroscience : MN. vol 30. issue 1-2. 2007-02-23. PMID:17192646.' |
at the vertebrate skeletal neuromuscular junction (nmj), two closely related enzymes can hydrolyze acetylcholine (ach): acetylcholinesterase (ache) and butyrylcholinesterase (bche). |
2007-02-23 |
2023-08-12 |
mouse |
| Laura E Paraoanu, Gunnar Steinert, Janine Klaczinski, Michaela Becker-Röck, Afrim Bytyqi, Paul G Laye. On functions of cholinesterases during embryonic development. Journal of molecular neuroscience : MN. vol 30. issue 1-2. 2007-02-23. PMID:17192676. |
this means that che functioning during development fits into the classical cholinergic neurotransmitter system: acetylcholine (ach), as a signal, binds to ach receptors and then is degraded by acetylcholinesterase (ache) as the terminating enzyme. |
2007-02-23 |
2023-08-12 |
Not clear |
| Laura Paleari, Sonya Trombino, Carla Falugi, Lorenzo Gallus, Sebastiano Carlone, Cristiano Angelini, Kristina Sepcic, Tom Turk, Marco Faimali, Douglas M Noonan, Adriana Albin. Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors. International journal of oncology. vol 29. issue 6. 2007-02-22. PMID:17088975. |
cholino-acetyltransferase (chat), vesicular acetylcholine transporter (vacht) and acetylcholinesterase (ache) were observed in nsclc tumor biopsies and in nsclc cell lines. |
2007-02-22 |
2023-08-12 |
mouse |
| Itamar Willner, Bilha Willner, Eugenii Kat. Biomolecule-nanoparticle hybrid systems for bioelectronic applications. Bioelectrochemistry (Amsterdam, Netherlands). vol 70. issue 1. 2007-02-20. PMID:16750941. |
a hybrid system consisting of acetylcholine esterase (ache)/cds-nps is immobilized in a monolayer configuration on an electrode. |
2007-02-20 |
2023-08-12 |
Not clear |
| Björn Schilström, Vladimir B Ivanov, Charlotte Wiker, Torgny H Svensso. Galantamine enhances dopaminergic neurotransmission in vivo via allosteric potentiation of nicotinic acetylcholine receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 1. 2007-02-09. PMID:16641937. |
galantamine is an allosteric modulator of nicotinic acetylcholine receptors (nachrs) and, at higher doses, an acetylcholine esterase (ache) inhibitor. |
2007-02-09 |
2023-08-12 |
rat |
| Jun-ichi Anza. [Use of biosensors for detecting organophosphorus agents]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 126. issue 12. 2007-02-07. PMID:17139155. |
acetylcholine esterase (ache)-immobilized electrodes have been used for detecting ache inhibitors including organophosphorus and carbamate pesticides. |
2007-02-07 |
2023-08-12 |
Not clear |
| Saharudin Haron, Asim K Ra. Optical biodetection of cadmium and lead ions in water. Medical engineering & physics. vol 28. issue 10. 2007-01-30. PMID:17018258. |
the catalytic activities of urease and acetylcholine esterase (ache) were inhibited by the presence of cadmium (cd(2+)) and lead (pb(2+)) ions. |
2007-01-30 |
2023-08-12 |
Not clear |
| Gabriel Zimmerman, Hermona Sore. Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission. Cell and tissue research. vol 326. issue 2. 2007-01-23. PMID:16802134. |
this unique termination mechanism makes acetylcholinesterase (ache), the enzyme in charge of executing acetylcholine breakdown, a key component of cholinergic signaling. |
2007-01-23 |
2023-08-12 |
Not clear |