| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhuo Qu, Jingze Zhang, Honggai Yang, Liqin Huo, Jing Gao, Hong Chen, Wenyuan Ga. Protective effect of tetrahydropalmatine against d-galactose induced memory impairment in rat. Physiology & behavior. vol 154. 2016-09-30. PMID:26592138. |
thp treatment was also found to reverse the abnormality of acetylcholine (ach) levels and acetylcholinesterase (ache) activities. |
2016-09-30 |
2023-08-13 |
rat |
| Nan Zhang, Zheng-Yuan Ma, Yi-Fan Ruan, Wei-Wei Zhao, Jing-Juan Xu, Hong-Yuan Che. Simultaneous Photoelectrochemical Immunoassay of Dual Cardiac Markers Using Specific Enzyme Tags: A Proof of Principle for Multiplexed Bioanalysis. Analytical chemistry. vol 88. issue 4. 2016-09-28. PMID:26841098. |
in this letter, on the basis of the cds quantum dots functionalized tio2 nanotubes electrode, we proposed a simultaneous photoelectrochemical (pec) immunoassay of dual cardiac markers using specific enzyme tags of alkaline phosphatase (alp) and acetylcholine esterase (ache). |
2016-09-28 |
2023-08-13 |
Not clear |
| Nadia Khan, Ali Saad, Syed M Nurulain, Fouad H Darras, Michael Decker, Bassem Sade. The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats. Behavioural brain research. vol 297. 2016-09-20. PMID:26467607. |
both the histamine h3 receptor (h3r) and acetylcholine esterase (ache) are involved in the regulation of release and metabolism of acetylcholine and several other central neurotransmitters. |
2016-09-20 |
2023-08-13 |
rat |
| Gamal Mohamed Mors. Bioaccumulation and neurotoxicity of dithiopyridine herbicide in the brain of freshwater fish, Cyprinus carpio. Toxicology and industrial health. vol 31. issue 12. 2016-09-16. PMID:23681548. |
one-way analysis of variance revealed that the acute and sublethal exposure to the herbicide as well as the experimental periods caused significant reduction in the concentrations of catecholamines (dopamine (da) and norepinephrine (ne)), elevation of acetylcholine (ach), and was associated with a marked decrease in the activity of acetylcholinesterase (ache). |
2016-09-16 |
2023-08-12 |
Not clear |
| Ana Cristina Castillo-González, Juan Pablo Pelegrín-Hernández, Susana Nieto-Cerón, Antonio Piñero Madrona, José Antonio Noguera, María Fuensanta López-Moreno, José Neptuno Rodríguez-López, Cecilio J Vidal, Diego Hellín-Meseguer, Juan Cabezas-Herrer. Unbalanced acetylcholinesterase activity in larynx squamous cell carcinoma. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:26002584. |
the ache activity in non-cancerous tissues (0.248 ± 0.030 milliunits per milligram of wet tissue; mu/mg) demonstrates that upper respiratory tissues express sufficient ache activity for controlling the level of acetylcholine (ach). |
2016-09-14 |
2023-08-13 |
Not clear |
| Malte Haupt, Vivien Kauschke, Jonas Sender, Marian Kampschulte, Anna Kovtun, Lutz Dürselen, Christian Heiss, Katrin Susanne Lip. Bone status of adult female butyrylcholinesterase gene-deficient mice. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:26138460. |
butyrylcholinesterase (bche) degrades acetylcholine in addition to acetylcholinesterase (ache) which is involved in embryonic development of limbs. |
2016-09-14 |
2023-08-13 |
mouse |
| Vivien Kauschke, Mathias Kneffel, Wolfgang Floel, Sonja Hartmann, Marian Kampschulte, Lutz Dürselen, Anita Ignatius, Reinhard Schnettler, Christian Heiss, Katrin Susanne Lip. Bone status of acetylcholinesterase-knockout mice. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:26250336. |
acetylcholinesterase (ache) hydrolyzes acetylcholine (ach) to acetate and choline and thereby terminates nerve impulse transmission. |
2016-09-14 |
2023-08-13 |
mouse |
| Christina Nassenstein, Silke Wiegand, Katrin S Lips, Guanfeng Li, Jochen Klein, Wolfgang Kumme. Cholinergic activation of the murine trachealis muscle via non-vesicular acetylcholine release involving low-affinity choline transporters. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:26278668. |
in addition to quantal, vesicular release of acetylcholine (ach), there is also non-quantal release at the motor endplate which is insufficient to evoke postsynaptic responses unless acetylcholinesterase (ache) is inhibited. |
2016-09-14 |
2023-08-13 |
mouse |
| b' Danijela B Vu\\xc4\\x8devi\\xc4\\x87, Ivana B Cerovi\\xc4\\x87, Du\\xc5\\xa1an R Mladenovi\\xc4\\x87, Milena N Veskovi\\xc4\\x87, Ivana Stevanovi\\xc4\\x87, Bojan Z Jorga\\xc4\\x8devi\\xc4\\x87, Rada Je\\xc5\\xa1i\\xc4\\x87 Vuki\\xc4\\x87evi\\xc4\\x87, Tatjana S Radosavljevi\\xc4\\x8. Methionine-choline deprivation alters liver and brain acetylcholinesterase activity in C57BL6 mice. General physiology and biophysics. vol 35. issue 3. 2016-09-13. PMID:27174897.' |
choline and methionine are precursors of acetylcholine, whose hydrolysis is catalyzed by acetylcholinesterase (ache). |
2016-09-13 |
2023-08-13 |
mouse |
| Michael F Santillo, Yitong Li. A fluorescence assay for measuring acetylcholinesterase activity in rat blood and a human neuroblastoma cell line (SH-SY5Y). Journal of pharmacological and toxicological methods. vol 76. 2016-09-12. PMID:26165232. |
acetylcholinesterase (ache) is an enzyme responsible for metabolism of the neurotransmitter acetylcholine, and inhibition of ache can have therapeutic applications (e.g., drugs for alzheimer's disease) or neurotoxic consequences (e.g., pesticides). |
2016-09-12 |
2023-08-13 |
human |
| Michael F Santillo, Yitong Li. A fluorescence assay for measuring acetylcholinesterase activity in rat blood and a human neuroblastoma cell line (SH-SY5Y). Journal of pharmacological and toxicological methods. vol 76. 2016-09-12. PMID:26165232. |
therefore, an alternative assay was developed, in which ache activity was determined by measuring fluorescence of resorufin produced from coupled enzyme reactions involving acetylcholine and amplex red (10-acetyl-3,7-dihydroxyphenoxazine). |
2016-09-12 |
2023-08-13 |
human |
| Saw Simeon, Nuttapat Anuwongcharoen, Watshara Shoombuatong, Aijaz Ahmad Malik, Virapong Prachayasittikul, Jarl E S Wikberg, Chanin Nantasenama. Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking. PeerJ. vol 4. 2016-09-07. PMID:27602288. |
acetylcholinesterase (ache) is an enzyme that catalyzes the breakdown of the neurotransmitter acetylcholine that is essential for cognition and memory. |
2016-09-07 |
2023-08-13 |
human |
| Heng-Wen Chen, Xuan-Hui He, Rong Yuan, Ben-Jun Wei, Zhong Chen, Jun-Xing Dong, Jie Wan. Sesquiterpenes and a monoterpenoid with acetylcholinesterase (AchE) inhibitory activity from Valeriana officinalis var. latiofolia in vitro and in vivo. Fitoterapia. vol 110. 2016-09-06. PMID:26976216. |
the contents of acetylcholine (ach), acetylcholine transferase (chat) and ache in mice brains were determined by colorimetry. |
2016-09-06 |
2023-08-13 |
mouse |
| Allister Vale, Marcello Lott. Organophosphorus and carbamate insecticide poisoning. Handbook of clinical neurology. vol 131. 2016-08-18. PMID:26563788. |
both organophosphorus (op) and carbamate insecticides inhibit acetylcholinesterase (ache), which results in accumulation of acetylcholine (ach) at autonomic and some central synapses and at autonomic postganglionic and neuromuscular junctions. |
2016-08-18 |
2023-08-13 |
human |
| Sehan Lee, Mace G Barro. Development of 3D-QSAR Model for Acetylcholinesterase Inhibitors Using a Combination of Fingerprint, Molecular Docking, and Structure-Based Pharmacophore Approaches. Toxicological sciences : an official journal of the Society of Toxicology. vol 148. issue 1. 2016-08-16. PMID:26202430. |
acetylcholinesterase (ache), a serine hydrolase vital for regulating the neurotransmitter acetylcholine in animals, has been used as a target for drugs and pesticides. |
2016-08-16 |
2023-08-13 |
Not clear |
| Huan Qu, Min Lv, Xiang Yu, Xihong Lian, Hui X. Discovery of Some Piperine-Based Phenylsulfonylhydrazone Derivatives as Potent Botanically Narcotic Agents. Scientific reports. vol 5. 2016-08-08. PMID:26268805. |
more importantly, 6c selectively displayed the inhibition activity on acetylcholine esterase (ache) of m. separata. |
2016-08-08 |
2023-08-13 |
Not clear |
| Chand D Basha, Rajarami G Redd. Long-term changes in brain cholinergic system and behavior in rats following gestational exposure to lead: protective effect of calcium supplement. Interdisciplinary toxicology. vol 8. issue 4. 2016-08-03. PMID:27486377. |
biochemical analysis showed decrease in synaptosomal acetylcholinesterase (ache) activity and an increase in acetylcholine (ach) levels in the cortex, cerebellum and hippocampus on pnd 14, pnd 21, pnd 28 and in the four-month age group of rats following pb exposure. |
2016-08-03 |
2023-08-13 |
rat |
| K V Niessen, S Muschik, F Langguth, S Rappenglück, T Seeger, H Thiermann, F Wore. Functional analysis of Torpedo californica nicotinic acetylcholine receptors in multiple activation states by SSM-based electrophysiology. Toxicology letters. vol 247. 2016-07-25. PMID:26851639. |
inhibited ache results in accumulation of acetylcholine in the synaptic cleft and thus the desensitisation of the nicotinic acetylcholine receptor (nachr) in the postsynaptic membrane is provoked. |
2016-07-25 |
2023-08-13 |
Not clear |
| Gökhan Demirci, Yasemin İspirli Doğaç, Mustafa Tek. A selective molecularly imprinted polymer for immobilization of acetylcholinesterase (AChE): an active enzyme targeted and efficient method. Journal of molecular recognition : JMR. vol 28. issue 11. 2016-07-19. PMID:25857716. |
in the present study, we immobilized acetylcholinesterase (ache) enzyme onto acetylcholine removed imprinted polymer and acetylcholine containing polymer. |
2016-07-19 |
2023-08-13 |
Not clear |
| Gökhan Demirci, Yasemin İspirli Doğaç, Mustafa Tek. A selective molecularly imprinted polymer for immobilization of acetylcholinesterase (AChE): an active enzyme targeted and efficient method. Journal of molecular recognition : JMR. vol 28. issue 11. 2016-07-19. PMID:25857716. |
first, the polymers were produced with acetylcholine, substrate of ache, by dispersion polymerization. |
2016-07-19 |
2023-08-13 |
Not clear |