| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Meegle S Mathew, Ananya Baksi, T Pradeep, Kuruvilla Josep. Choline-induced selective fluorescence quenching of acetylcholinesterase conjugated Au@BSA clusters. Biosensors & bioelectronics. vol 81. 2016-12-28. PMID:26921554. |
the gold quantum clusters (auqc@bsa) synthesized using bovine serum albumin and conjugated with acetylcholinesterase (ache), an enzyme specific for acetylcholine, resulting in auqc@bsa-ache. |
2016-12-28 |
2023-08-13 |
cattle |
| Meegle S Mathew, Ananya Baksi, T Pradeep, Kuruvilla Josep. Choline-induced selective fluorescence quenching of acetylcholinesterase conjugated Au@BSA clusters. Biosensors & bioelectronics. vol 81. 2016-12-28. PMID:26921554. |
the enzyme, ache hydrolyzes acetylcholine (ach) to choline (ch) which in turn interacts with auqc@bsa-ache and quenches its fluorescence, enabling sensing. |
2016-12-28 |
2023-08-13 |
cattle |
| Adel El-Terras, Mohamed Mohamed Soliman, Adel Alkhedaide, Hossam Fouad Attia, Abdullah Alharthy, Abdel Elah Banaj. Carbonated soft drinks induce oxidative stress and alter the expression of certain genes in the brains of Wistar rats. Molecular medicine reports. vol 13. issue 4. 2016-12-28. PMID:26936207. |
rats administered carbonated soft drinks also exhibited decreased monoamine oxidase a (mao‑a) and acetylcholine esterase (ache) serum and mrna levels in the brain. |
2016-12-28 |
2023-08-13 |
rat |
| Pedro Teixeira, Patrícia Napoleão, Carlota Saldanh. S-nitrosoglutathione efflux in the erythrocyte. Clinical hemorheology and microcirculation. vol 60. issue 4. 2016-12-19. PMID:24958331. |
gsno has been regarded as a store and transporter of no, with significant interest as a potential therapeutic agent, acting as an no donor.no metabolism inside the erythrocyte generates several derivatives, which can be altered by external and internal stimuli such as acetylcholine (ach), a natural substrate of acetylcholinesterase (ache). |
2016-12-19 |
2023-08-13 |
Not clear |
| Samanta Oliveira Loureiro, Daniele Susana Volkart Sidegum, Helena Biasibetti, Mery Stefani Leivas Pereira, Diogo Losch de Oliveira, Regina Pessoa-Pureur, Angela T S Wys. Crosstalk Among Disrupted Glutamatergic and Cholinergic Homeostasis and Inflammatory Response in Mechanisms Elicited by Proline in Astrocytes. Molecular neurobiology. vol 53. issue 2. 2016-12-13. PMID:25579384. |
we also evidenced misregulation of cholinergic anti-inflammatory system with increased acetylcholinesterase (ache) activity and decreased acetylcholine (ach) levels, contributing to the inflammatory status in pro-treated astrocytes. |
2016-12-13 |
2023-08-13 |
rat |
| Jean Froment, Katherine Langford, Knut Erik Tollefsen, Inger Lise N Bråte, Steven J Brooks, Kevin V Thoma. Identification of petrogenic produced water components as acetylcholine esterase inhibitors. Environmental pollution (Barking, Essex : 1987). vol 215. 2016-12-13. PMID:27176761. |
effect-directed analysis (eda) was applied to identify acetylcholine esterase (ache) inhibitors in produced water. |
2016-12-13 |
2023-08-13 |
Not clear |
| Susimaire P Mantoani, Talita P C Chierrito, Adriana F L Vilela, Carmen L Cardoso, Ana Martínez, Ivone Carvalh. Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors. Molecules (Basel, Switzerland). vol 21. issue 2. 2016-11-07. PMID:26861273. |
currently, the only strategy for palliative treatment of ad is to inhibit acetylcholinesterase (ache) in order to increase the concentration of acetylcholine in the synaptic cleft. |
2016-11-07 |
2023-08-13 |
Not clear |
| Susimaire P Mantoani, Talita P C Chierrito, Adriana F L Vilela, Carmen L Cardoso, Ana Martínez, Ivone Carvalh. Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors. Molecules (Basel, Switzerland). vol 21. issue 2. 2016-11-07. PMID:26861273. |
it is known that ache has two binding sites: the peripheral site, responsible for the interactions with aβ, and the catalytic site, related with acetylcholine hydrolysis. |
2016-11-07 |
2023-08-13 |
Not clear |
| Jie-Qiong Ma, Rong-Zhen Luo, Hai-Xia Jiang, Chan-Min Li. Quercitrin offers protection against brain injury in mice by inhibiting oxidative stress and inflammation. Food & function. vol 7. issue 1. 2016-10-19. PMID:26510118. |
quercitrin also prevented ccl4 induced cerebral function disorders associated with its ability to inhibit the activities of monoamine oxidase (mao), acetylcholine esterase (ache) and the n-methyl-d-aspartate receptor 2b subunit (nr2b). |
2016-10-19 |
2023-08-13 |
mouse |
| Cui Ye, Min-Qiang Wang, Xia Zhong, Shihong Chen, Yaqin Chai, Ruo Yua. Highly sensitive electrochemiluminescenc assay of acetylcholinesterase activity based on dual biomarkers using Pd-Au nanowires as immobilization platform. Biosensors & bioelectronics. vol 79. 2016-10-19. PMID:26686921. |
in the presence of ache and choline oxidase (chox), acetylcholine (atcl) is hydrolyzed by ache to generate thiocholine, then thiocholine is catalyzed by chox to produce h2o2 in situ, which serves as the coreactant to effectively enhance the ecl intensity in luminol-ecl system. |
2016-10-19 |
2023-08-13 |
Not clear |
| Parham Taslimi, Ilhami Gulcin, Bunyamin Ozgeris, Suleyman Goksu, Ferhan Tumer, Saleh H Alwasel, Claudiu T Supura. The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives. Journal of enzyme inhibition and medicinal chemistry. vol 31. issue 1. 2016-10-06. PMID:25697270. |
acetylcholine esterase (ache. |
2016-10-06 |
2023-08-13 |
human |
| Zhuo Qu, Jingze Zhang, Honggai Yang, Liqin Huo, Jing Gao, Hong Chen, Wenyuan Ga. Protective effect of tetrahydropalmatine against d-galactose induced memory impairment in rat. Physiology & behavior. vol 154. 2016-09-30. PMID:26592138. |
thp treatment was also found to reverse the abnormality of acetylcholine (ach) levels and acetylcholinesterase (ache) activities. |
2016-09-30 |
2023-08-13 |
rat |
| Nan Zhang, Zheng-Yuan Ma, Yi-Fan Ruan, Wei-Wei Zhao, Jing-Juan Xu, Hong-Yuan Che. Simultaneous Photoelectrochemical Immunoassay of Dual Cardiac Markers Using Specific Enzyme Tags: A Proof of Principle for Multiplexed Bioanalysis. Analytical chemistry. vol 88. issue 4. 2016-09-28. PMID:26841098. |
in this letter, on the basis of the cds quantum dots functionalized tio2 nanotubes electrode, we proposed a simultaneous photoelectrochemical (pec) immunoassay of dual cardiac markers using specific enzyme tags of alkaline phosphatase (alp) and acetylcholine esterase (ache). |
2016-09-28 |
2023-08-13 |
Not clear |
| Nadia Khan, Ali Saad, Syed M Nurulain, Fouad H Darras, Michael Decker, Bassem Sade. The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats. Behavioural brain research. vol 297. 2016-09-20. PMID:26467607. |
both the histamine h3 receptor (h3r) and acetylcholine esterase (ache) are involved in the regulation of release and metabolism of acetylcholine and several other central neurotransmitters. |
2016-09-20 |
2023-08-13 |
rat |
| Gamal Mohamed Mors. Bioaccumulation and neurotoxicity of dithiopyridine herbicide in the brain of freshwater fish, Cyprinus carpio. Toxicology and industrial health. vol 31. issue 12. 2016-09-16. PMID:23681548. |
one-way analysis of variance revealed that the acute and sublethal exposure to the herbicide as well as the experimental periods caused significant reduction in the concentrations of catecholamines (dopamine (da) and norepinephrine (ne)), elevation of acetylcholine (ach), and was associated with a marked decrease in the activity of acetylcholinesterase (ache). |
2016-09-16 |
2023-08-12 |
Not clear |
| Ana Cristina Castillo-González, Juan Pablo Pelegrín-Hernández, Susana Nieto-Cerón, Antonio Piñero Madrona, José Antonio Noguera, María Fuensanta López-Moreno, José Neptuno Rodríguez-López, Cecilio J Vidal, Diego Hellín-Meseguer, Juan Cabezas-Herrer. Unbalanced acetylcholinesterase activity in larynx squamous cell carcinoma. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:26002584. |
the ache activity in non-cancerous tissues (0.248 ± 0.030 milliunits per milligram of wet tissue; mu/mg) demonstrates that upper respiratory tissues express sufficient ache activity for controlling the level of acetylcholine (ach). |
2016-09-14 |
2023-08-13 |
Not clear |
| Malte Haupt, Vivien Kauschke, Jonas Sender, Marian Kampschulte, Anna Kovtun, Lutz Dürselen, Christian Heiss, Katrin Susanne Lip. Bone status of adult female butyrylcholinesterase gene-deficient mice. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:26138460. |
butyrylcholinesterase (bche) degrades acetylcholine in addition to acetylcholinesterase (ache) which is involved in embryonic development of limbs. |
2016-09-14 |
2023-08-13 |
mouse |
| Vivien Kauschke, Mathias Kneffel, Wolfgang Floel, Sonja Hartmann, Marian Kampschulte, Lutz Dürselen, Anita Ignatius, Reinhard Schnettler, Christian Heiss, Katrin Susanne Lip. Bone status of acetylcholinesterase-knockout mice. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:26250336. |
acetylcholinesterase (ache) hydrolyzes acetylcholine (ach) to acetate and choline and thereby terminates nerve impulse transmission. |
2016-09-14 |
2023-08-13 |
mouse |
| Christina Nassenstein, Silke Wiegand, Katrin S Lips, Guanfeng Li, Jochen Klein, Wolfgang Kumme. Cholinergic activation of the murine trachealis muscle via non-vesicular acetylcholine release involving low-affinity choline transporters. International immunopharmacology. vol 29. issue 1. 2016-09-14. PMID:26278668. |
in addition to quantal, vesicular release of acetylcholine (ach), there is also non-quantal release at the motor endplate which is insufficient to evoke postsynaptic responses unless acetylcholinesterase (ache) is inhibited. |
2016-09-14 |
2023-08-13 |
mouse |
| b' Danijela B Vu\\xc4\\x8devi\\xc4\\x87, Ivana B Cerovi\\xc4\\x87, Du\\xc5\\xa1an R Mladenovi\\xc4\\x87, Milena N Veskovi\\xc4\\x87, Ivana Stevanovi\\xc4\\x87, Bojan Z Jorga\\xc4\\x8devi\\xc4\\x87, Rada Je\\xc5\\xa1i\\xc4\\x87 Vuki\\xc4\\x87evi\\xc4\\x87, Tatjana S Radosavljevi\\xc4\\x8. Methionine-choline deprivation alters liver and brain acetylcholinesterase activity in C57BL6 mice. General physiology and biophysics. vol 35. issue 3. 2016-09-13. PMID:27174897.' |
choline and methionine are precursors of acetylcholine, whose hydrolysis is catalyzed by acetylcholinesterase (ache). |
2016-09-13 |
2023-08-13 |
mouse |